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YJJL - L-galactonate transporter
UniProt: P39398 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12588
Length: 453 (401)
Sequences: 62154
Seq/Len: 155.00
YJJL
Paralog alert: 0.90 [within 20: 0.65] - ratio of genomes with paralogs
Cluster includes: AMPG ARAE ARAJ BCR CYNX DGOT DTPA DTPB DTPD EMRB EMRD EMRY ENTS EXUT FSR FUCP GALP GARP GLPT GUDP HCAT HSRA KGTP LACY LPLT MDFA MDTD MDTG MDTH MDTL MDTM MELB MHPT NANT NARK NARU NEPI NUPG PROP RHMT SETA SETB SETC SHIA SOTB TSGA UHPC UHPT UIDB XAPB XYLE YAAU YAGG YAJR YBJJ YCAD YDEE YDFJ YDHC YDHP YDIM YDIN YDJE YDJK YEAN YEBQ YEGT YFCJ YGAY YGCS YHHS YHJE YHJX YICJ YIHN YIHO YIHP YJDL YJHB YJIJ YJJL YNFM YQCE
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
128_H 132_Q 4.179 1.00
116_F 143_G 3.547 1.00
123_M 136_V 3.364 1.00
125_G 200_I 3.15 1.00
89_A 138_I 2.892 1.00
118_S 206_G 2.856 1.00
131_T 135_L 2.853 1.00
120_F 136_V 2.819 1.00
97_C 146_P 2.736 1.00
106_P 157_D 2.708 1.00
129_N 132_Q 2.657 1.00
165_G 318_D 2.554 1.00
384_V 392_V 2.502 1.00
159_F 167_P 2.495 1.00
113_G 146_P 2.476 1.00
130_F 134_V 2.462 1.00
291_D 294_S 2.454 1.00
267_S 403_C 2.429 1.00
75_S 78_E 2.327 1.00
120_F 143_G 2.315 1.00
120_F 139_G 2.304 1.00
163_E 166_R 2.303 1.00
102_D 390_A 2.263 1.00
93_A 142_I 2.25 1.00
251_R 255_R 2.232 1.00
271_Y 407_A 2.214 1.00
309_G 367_F 2.082 1.00
341_C 368_C 2.053 1.00
305_F 363_G 2.038 1.00
348_I 361_L 2.004 1.00
160_N 163_E 1.983 1.00
127_V 132_Q 1.954 1.00
122_A 203_G 1.931 1.00
127_V 136_V 1.924 1.00
385_A 388_M 1.923 1.00
193_M 197_G 1.921 1.00
426_I 430_C 1.915 1.00
85_V 138_I 1.838 1.00
82_L 133_F 1.815 1.00
107_R 111_G 1.814 1.00
211_I 215_M 1.81 1.00
101_L 150_C 1.807 1.00
78_E 130_F 1.804 1.00
93_A 145_A 1.792 1.00
120_F 140_M 1.778 1.00
85_V 134_V 1.744 1.00
322_K 382_V 1.717 1.00
111_G 214_Y 1.717 1.00
124_S 136_V 1.704 1.00
231_A 234_N 1.701 1.00
111_G 210_A 1.7 1.00
48_F 174_A 1.697 1.00
343_A 436_A 1.644 1.00
275_L 411_T 1.641 1.00
74_L 130_F 1.633 1.00
315_Y 319_W 1.627 1.00
321_V 324_G 1.614 1.00
99_P 103_R 1.606 1.00
89_A 93_A 1.597 1.00
343_A 433_A 1.596 1.00
345_F 361_L 1.592 1.00
105_G 108_L 1.575 1.00
115_F 210_A 1.572 1.00
252_S 255_R 1.569 1.00
356_M 360_L 1.562 1.00
118_S 210_A 1.535 1.00
74_L 78_E 1.531 1.00
252_S 388_M 1.517 1.00
124_S 133_F 1.515 1.00
132_Q 136_V 1.511 1.00
263_M 399_A 1.51 1.00
213_W 217_Y 1.5 1.00
108_L 112_L 1.469 1.00
123_M 126_M 1.457 1.00
338_G 371_F 1.455 1.00
100_L 109_M 1.434 1.00
166_R 318_D 1.432 1.00
314_G 318_D 1.428 1.00
112_L 116_F 1.426 1.00
118_S 203_G 1.425 1.00
104_K 109_M 1.423 1.00
67_T 70_E 1.42 1.00
40_Q 163_E 1.415 1.00
290_L 294_S 1.41 1.00
345_F 368_C 1.406 0.99
274_W 404_A 1.397 0.99
200_I 204_V 1.396 0.99
336_I 436_A 1.396 0.99
122_A 126_M 1.38 0.99
100_L 104_K 1.375 0.99
161_I 164_R 1.366 0.99
93_A 96_P 1.365 0.99
98_G 102_D 1.352 0.99
294_S 297_L 1.35 0.99
194_G 197_G 1.347 0.99
305_F 309_G 1.347 0.99
413_F 417_T 1.347 0.99
302_P 366_L 1.331 0.99
340_F 436_A 1.33 0.99
88_L 405_S 1.316 0.99
125_G 203_G 1.311 0.99
116_F 120_F 1.31 0.99
316_V 320_L 1.309 0.99
135_L 139_G 1.298 0.99
285_Q 292_L 1.285 0.99
285_Q 295_T 1.271 0.99
312_V 315_Y 1.265 0.99
113_G 143_G 1.264 0.99
156_N 164_R 1.256 0.99
108_L 111_G 1.255 0.99
226_T 231_A 1.254 0.99
131_T 134_V 1.252 0.99
125_G 196_R 1.247 0.99
212_G 216_L 1.241 0.98
102_D 391_S 1.24 0.98
104_K 108_L 1.235 0.98
184_P 300_A 1.226 0.98
343_A 429_G 1.222 0.98
340_F 344_A 1.221 0.98
343_A 347_L 1.209 0.98
84_S 405_S 1.202 0.98
118_S 207_I 1.195 0.98
155_I 171_F 1.194 0.98
347_L 429_G 1.188 0.98
108_L 219_N 1.18 0.98
189_M 197_G 1.176 0.98
350_P 426_I 1.171 0.98
119_L 123_M 1.17 0.97
55_Y 175_S 1.168 0.97
272_T 432_T 1.167 0.97
76_A 416_D 1.167 0.97
197_G 200_I 1.158 0.97
157_D 389_T 1.154 0.97
260_W 264_L 1.148 0.97
259_M 263_M 1.146 0.97
309_G 312_V 1.145 0.97
283_Y 288_Y 1.144 0.97
337_A 341_C 1.142 0.97
50_A 147_M 1.141 0.97
101_L 106_P 1.14 0.97
69_R 79_I 1.14 0.97
86_F 90_Y 1.139 0.97
96_P 99_P 1.128 0.97
230_Q 234_N 1.128 0.97
89_A 141_G 1.126 0.97
356_M 359_V 1.12 0.96
109_M 112_L 1.119 0.96
111_G 213_W 1.117 0.96
64_A 190_M 1.115 0.96
52_V 178_G 1.114 0.96
191_L 293_K 1.112 0.96
46_L 212_G 1.111 0.96
123_M 132_Q 1.111 0.96
313_N 371_F 1.11 0.96
304_L 308_A 1.102 0.96
132_Q 135_L 1.101 0.96
56_L 182_S 1.101 0.96
67_T 71_E 1.094 0.96
164_R 382_V 1.09 0.96
210_A 214_Y 1.089 0.96
98_G 390_A 1.088 0.96
430_C 434_A 1.088 0.96
423_L 426_I 1.084 0.96
350_P 429_G 1.084 0.96
360_L 364_M 1.082 0.96
226_T 229_E 1.082 0.96
50_A 110_L 1.079 0.95
317_T 375_S 1.079 0.95
77_T 416_D 1.073 0.95
166_R 170_F 1.072 0.95
347_L 351_Q 1.066 0.95
204_V 208_F 1.063 0.95
128_H 196_R 1.062 0.95
412_G 416_D 1.062 0.95
315_Y 318_D 1.059 0.95
91_G 398_F 1.058 0.95
245_L 249_E 1.056 0.95
86_F 144_E 1.055 0.95
297_L 301_I 1.053 0.95
284_L 290_L 1.052 0.95
184_P 188_A 1.049 0.94
81_A 409_I 1.044 0.94
403_C 407_A 1.044 0.94
357_T 360_L 1.041 0.94
102_D 106_P 1.04 0.94
422_R 426_I 1.037 0.94
81_A 85_V 1.035 0.94
266_F 396_Q 1.032 0.94
105_G 219_N 1.03 0.94
380_I 396_Q 1.027 0.94
84_S 409_I 1.021 0.93
106_P 219_N 1.02 0.93
354_T 357_T 1.016 0.93
126_M 200_I 1.015 0.93
71_E 196_R 1.013 0.93
111_G 115_F 1.011 0.93
207_I 211_I 1.01 0.93
105_G 109_M 1.005 0.93
293_K 297_L 1.002 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1pw4A10.9471000.343Contact Map0.501
4j05A20.95141000.375Contact Map0.615
3wdoA10.86981000.382Contact Map0.643
3o7qA10.89851000.393Contact Map0.63
2gfpA20.81681000.412Contact Map0.174
2cfqA10.87641000.412Contact Map0.49
4ldsA20.89621000.426Contact Map0.623
4gc0A10.90731000.43Contact Map0.706
4jr9A10.90511000.433Contact Map0.616
2xutA30.92721000.436Contact Map0.522
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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