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YJHB - Putative metabolite transport protein YjhB
UniProt: P39352 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12544
Length: 405 (379)
Sequences: 64796
Seq/Len: 170.97
YJHB
Paralog alert: 0.90 [within 20: 0.67] - ratio of genomes with paralogs
Cluster includes: AMPG ARAE ARAJ BCR CYNX DGOT DTPA DTPB DTPD EMRB EMRD EMRY ENTS EXUT FSR FUCP GALP GARP GLPT GUDP HCAT HSRA KGTP LACY LPLT MDFA MDTD MDTG MDTH MDTL MDTM MELB MHPT NANT NARK NARU NEPI NUPG PROP RHMT SETA SETB SETC SHIA SOTB TSGA UHPC UHPT UIDB XAPB XYLE YAAU YAGG YAJR YBJJ YCAD YDEE YDFJ YDHC YDHP YDIM YDIN YDJE YDJK YEAN YEBQ YEGT YFCJ YGAY YGCS YHHS YHJE YHJX YICJ YIHN YIHO YIHP YJDL YJHB YJIJ YJJL YNFM YQCE
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
101_T 105_M 4.261 1.00
89_I 116_G 3.693 1.00
96_L 109_C 3.671 1.00
98_G 173_F 3.38 1.00
62_A 111_F 3.164 1.00
93_G 109_C 3.086 1.00
70_F 119_G 2.962 1.00
79_R 130_E 2.951 1.00
91_S 179_V 2.825 1.00
102_N 105_M 2.781 1.00
104_Y 108_V 2.772 1.00
138_S 276_D 2.645 1.00
86_A 119_G 2.634 1.00
132_W 140_A 2.599 1.00
103_L 107_A 2.548 1.00
335_F 343_G 2.547 1.00
249_N 252_V 2.53 1.00
136_L 139_K 2.468 1.00
48_T 51_Q 2.406 1.00
93_G 112_I 2.339 1.00
93_G 116_G 2.334 1.00
66_G 115_L 2.322 1.00
75_D 341_G 2.308 1.00
80_K 84_M 2.176 1.00
133_P 136_L 2.172 1.00
280_V 333_D 2.103 1.00
166_Y 170_N 2.063 1.00
100_A 105_M 2.03 1.00
336_P 339_L 2.017 1.00
207_L 211_R 1.95 1.00
100_A 109_C 1.922 1.00
66_G 118_S 1.88 1.00
74_A 123_C 1.88 1.00
93_G 113_V 1.844 1.00
51_Q 103_L 1.831 1.00
72_A 76_K 1.826 1.00
95_G 176_L 1.812 1.00
58_V 107_A 1.801 1.00
47_I 103_L 1.796 1.00
55_I 106_L 1.782 1.00
58_V 111_F 1.782 1.00
78_G 81_P 1.751 1.00
97_S 109_C 1.739 1.00
62_A 66_G 1.724 1.00
279_G 282_K 1.704 1.00
21_W 147_G 1.701 1.00
97_S 106_L 1.622 1.00
47_I 51_Q 1.608 1.00
273_F 277_K 1.605 1.00
234_P 362_A 1.598 1.00
84_M 186_R 1.594 1.00
248_V 252_V 1.544 1.00
230_G 358_A 1.543 1.00
91_S 176_L 1.533 1.00
290_T 319_T 1.519 1.00
105_M 109_C 1.511 1.00
73_M 82_M 1.505 1.00
139_K 276_D 1.499 1.00
98_G 176_L 1.497 1.00
81_P 85_W 1.486 1.00
71_G 75_D 1.483 1.00
208_S 339_L 1.462 1.00
208_S 211_R 1.461 1.00
40_I 43_A 1.461 1.00
73_M 77_Y 1.454 1.00
66_G 69_F 1.449 1.00
77_Y 82_M 1.441 1.00
170_N 173_F 1.407 0.99
272_G 276_D 1.403 0.99
173_F 177_L 1.402 0.99
263_G 267_G 1.397 0.99
184_W 188_S 1.396 0.99
85_W 89_I 1.392 0.99
134_K 137_Q 1.391 0.99
61_I 356_M 1.387 0.99
167_G 170_N 1.385 0.99
86_A 116_G 1.385 0.99
244_A 253_I 1.385 0.99
294_F 319_T 1.373 0.99
274_V 278_I 1.361 0.99
312_C 315_G 1.358 0.99
96_L 99_I 1.358 0.99
89_I 93_G 1.357 0.99
104_Y 107_A 1.348 0.99
95_G 99_I 1.345 0.99
270_F 273_F 1.342 0.99
267_G 270_F 1.336 0.99
128_A 144_L 1.336 0.99
13_Q 136_L 1.322 0.99
263_G 314_F 1.322 0.99
81_P 84_M 1.321 0.99
252_V 255_T 1.318 0.99
244_A 250_T 1.317 0.99
28_G 148_F 1.308 0.99
130_E 340_R 1.304 0.99
157_Q 258_T 1.303 0.99
37_I 163_A 1.297 0.99
49_D 367_G 1.296 0.99
77_Y 81_P 1.282 0.99
281_K 285_V 1.279 0.99
364_Y 368_Y 1.278 0.99
287_G 322_G 1.275 0.99
311_L 315_G 1.272 0.99
69_F 72_A 1.272 0.99
129_V 137_Q 1.269 0.99
289_I 293_I 1.268 0.99
42_K 52_A 1.267 0.99
108_V 112_I 1.258 0.99
292_F 296_C 1.248 0.99
75_D 342_L 1.244 0.98
365_I 369_Y 1.208 0.98
162_F 170_N 1.205 0.98
50_I 367_G 1.204 0.98
282_K 286_V 1.204 0.98
98_G 169_R 1.196 0.98
92_V 96_L 1.191 0.98
23_G 120_E 1.19 0.98
78_G 82_M 1.184 0.98
82_M 85_W 1.181 0.98
62_A 114_G 1.18 0.98
57_T 356_M 1.176 0.98
74_A 79_R 1.17 0.97
243_L 248_V 1.162 0.97
25_V 151_G 1.161 0.97
267_G 318_F 1.161 0.97
242_Y 246_N 1.159 0.97
59_A 117_M 1.154 0.97
157_Q 161_Q 1.152 0.97
282_K 285_V 1.149 0.97
164_E 251_V 1.149 0.97
137_Q 333_D 1.137 0.97
71_G 341_G 1.134 0.97
29_F 155_A 1.131 0.97
210_F 216_S 1.128 0.97
99_I 173_F 1.128 0.97
273_F 276_D 1.126 0.97
262_L 266_T 1.126 0.97
339_L 342_L 1.118 0.96
290_T 294_F 1.112 0.96
40_I 44_D 1.11 0.96
354_G 358_A 1.103 0.96
64_P 349_N 1.096 0.96
225_C 229_F 1.091 0.96
139_K 143_F 1.089 0.96
75_D 79_R 1.085 0.96
57_T 360_V 1.085 0.96
42_K 47_I 1.084 0.96
54_L 360_V 1.083 0.96
127_Y 189_A 1.081 0.95
44_D 169_R 1.079 0.95
23_G 83_M 1.079 0.95
255_T 259_I 1.077 0.95
81_P 191_E 1.074 0.95
307_S 311_L 1.073 0.95
297_P 312_C 1.071 0.95
266_T 269_I 1.068 0.95
279_G 283_A 1.067 0.95
294_F 312_C 1.067 0.95
213_P 216_S 1.064 0.95
296_C 300_F 1.064 0.95
84_M 88_F 1.064 0.95
96_L 105_M 1.06 0.95
152_N 261_G 1.059 0.95
161_Q 165_V 1.056 0.95
110_R 114_G 1.053 0.95
54_L 58_V 1.052 0.95
331_I 347_I 1.051 0.94
278_I 283_A 1.049 0.94
105_M 108_V 1.045 0.94
297_P 300_F 1.045 0.94
30_D 33_M 1.044 0.94
292_F 384_A 1.044 0.94
286_V 290_T 1.043 0.94
64_P 356_M 1.041 0.94
233_W 355_G 1.041 0.94
266_T 270_F 1.025 0.93
226_F 354_G 1.022 0.93
37_I 41_I 1.021 0.93
363_T 367_G 1.019 0.93
139_K 273_F 1.018 0.93
42_K 49_D 1.013 0.93
278_I 282_K 1.012 0.93
37_I 171_S 1.008 0.93
127_Y 131_S 1.005 0.93
17_L 132_W 1.003 0.93
129_V 340_R 1.003 0.93
68_G 72_A 1.002 0.92
269_I 273_F 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1pw4A10.99011000.201Contact Map0.478
4j05A20.99751000.208Contact Map0.62
3wdoA10.97041000.217Contact Map0.611
2gfpA20.91111000.249Contact Map0.193
4ldsA20.98021000.253Contact Map0.607
4gc0A10.99261000.253Contact Map0.71
2cfqA10.96051000.259Contact Map0.477
3o7qA10.96051000.259Contact Map0.604
2xutA30.99261000.282Contact Map0.52
4apsA20.99261000.313Contact Map0.511
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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