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NARU - Nitrate/nitrite transporter NarU
UniProt: P37758 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12153
Length: 462 (385)
Sequences: 44671
Seq/Len: 116.03

NARU
Paralog alert: 0.90 [within 20: 0.57] - ratio of genomes with paralogs
Cluster includes: AMPG ARAE ARAJ BCR CYNX DGOT DTPA DTPB DTPD EMRB EMRD EMRY ENTS EXUT FSR FUCP GALP GARP GLPT GUDP HCAT HSRA KGTP LACY LPLT MDFA MDTD MDTG MDTH MDTL MDTM MELB MHPT NANT NARK NARU NEPI NUPG PROP RHMT SETA SETB SETC SHIA SOTB TSGA UHPC UHPT UIDB XAPB XYLE YAAU YAGG YAJR YBJJ YCAD YDEE YDFJ YDHC YDHP YDIM YDIN YDJE YDJK YEAN YEBQ YEGT YFCJ YGAY YGCS YHHS YHJE YHJX YICJ YIHN YIHO YIHP YJDL YJHB YJIJ YJJL YNFM YQCE
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
126_T 130_I 3.974 1.00
109_I 141_A 3.669 1.00
118_G 215_W 3.169 1.00
116_W 134_I 3.016 1.00
82_S 136_L 3.014 1.00
129_G 133_V 2.999 1.00
111_I 221_L 2.823 1.00
113_P 134_I 2.725 1.00
162_G 311_D 2.663 1.00
127_P 130_I 2.632 1.00
99_G 154_F 2.548 1.00
128_F 132_I 2.505 1.00
90_Y 143_A 2.378 1.00
325_F 358_T 2.363 1.00
68_T 71_Q 2.293 1.00
160_K 163_S 2.275 1.00
156_F 164_A 2.246 1.00
113_P 137_L 2.229 1.00
95_P 401_A 2.181 1.00
113_P 141_A 2.145 1.00
262_L 414_G 2.144 1.00
374_F 403_A 2.134 1.00
157_P 160_K 2.115 1.00
332_L 351_V 2.091 1.00
86_L 140_F 2.075 1.00
106_S 143_A 2.052 1.00
246_L 250_Q 2.011 1.00
437_K 441_I 1.991 1.00
120_A 134_I 1.922 1.00
302_A 357_L 1.913 1.00
104_V 225_T 1.908 1.00
266_G 418_I 1.873 1.00
100_R 104_V 1.865 1.00
346_I 350_A 1.857 1.00
78_L 136_L 1.841 1.00
120_A 130_I 1.829 1.00
329_F 351_V 1.818 1.00
78_L 132_I 1.805 1.00
108_A 225_T 1.792 1.00
115_V 218_V 1.782 1.00
298_I 353_M 1.762 1.00
113_P 138_C 1.757 1.00
104_V 229_W 1.749 1.00
75_L 131_F 1.721 1.00
327_A 444_I 1.718 1.00
226_I 230_S 1.707 1.00
327_A 447_V 1.695 1.00
315_G 372_V 1.691 1.00
314_G 317_R 1.684 1.00
71_Q 128_F 1.667 1.00
92_F 96_I 1.658 1.00
94_V 147_S 1.6 1.00
111_I 225_T 1.599 1.00
324_I 447_V 1.586 1.00
308_A 312_K 1.58 1.00
270_G 422_F 1.568 1.00
67_F 128_F 1.562 1.00
82_S 86_L 1.558 1.00
424_M 428_M 1.543 1.00
93_M 102_W 1.539 1.00
101_R 105_F 1.535 1.00
91_S 95_P 1.534 1.00
247_P 250_Q 1.528 1.00
81_V 416_F 1.523 1.00
307_G 311_D 1.523 1.00
98_G 101_R 1.522 1.00
40_V 171_L 1.517 1.00
195_L 212_N 1.511 1.00
117_L 134_I 1.509 1.00
375_R 399_E 1.488 1.00
320_L 447_V 1.475 1.00
32_A 160_K 1.468 1.00
189_V 195_L 1.464 1.00
67_F 71_Q 1.454 1.00
334_F 437_K 1.453 1.00
344_N 347_A 1.448 1.00
93_M 97_F 1.445 1.00
117_L 131_F 1.44 1.00
441_I 445_V 1.436 1.00
116_W 119_I 1.427 1.00
97_F 102_W 1.424 1.00
97_F 101_R 1.416 1.00
77_A 416_F 1.407 0.99
59_N 62_K 1.402 0.99
86_L 142_G 1.382 0.99
163_S 311_D 1.379 0.99
181_L 185_L 1.367 0.99
158_K 161_Q 1.354 0.99
152_I 168_N 1.353 0.99
324_I 328_I 1.339 0.99
86_L 89_P 1.338 0.99
329_F 358_T 1.336 0.99
298_I 302_A 1.326 0.99
327_A 331_A 1.316 0.99
130_I 134_I 1.316 0.99
258_S 410_I 1.314 0.99
115_V 119_I 1.309 0.99
227_A 231_G 1.308 0.99
309_I 313_F 1.305 0.99
331_A 335_L 1.298 0.99
105_F 109_I 1.298 0.99
109_I 113_P 1.297 0.99
269_I 415_G 1.295 0.99
305_V 308_A 1.293 0.99
69_T 427_N 1.292 0.99
101_R 104_V 1.291 0.99
287_N 290_R 1.289 0.99
331_A 440_L 1.288 0.99
181_L 293_F 1.281 0.99
133_V 137_L 1.268 0.99
327_A 440_L 1.268 0.99
267_S 443_Y 1.252 0.99
101_R 234_D 1.252 0.99
375_R 398_T 1.248 0.99
280_K 285_D 1.244 0.98
106_S 141_A 1.231 0.98
334_F 440_L 1.228 0.98
215_W 219_P 1.224 0.98
120_A 126_T 1.222 0.98
317_R 321_I 1.215 0.98
316_V 320_L 1.215 0.98
95_P 402_A 1.214 0.98
111_I 218_V 1.207 0.98
375_R 397_V 1.206 0.98
196_G 212_N 1.203 0.98
322_N 361_L 1.194 0.98
350_A 354_G 1.188 0.98
118_G 218_V 1.176 0.98
112_I 116_W 1.174 0.98
295_G 356_F 1.171 0.98
130_I 133_V 1.17 0.97
91_S 401_A 1.165 0.97
36_L 156_F 1.164 0.97
247_P 399_E 1.161 0.97
368_Q 372_V 1.157 0.97
444_I 448_L 1.146 0.97
185_L 189_V 1.142 0.97
118_G 211_A 1.14 0.97
280_K 288_I 1.14 0.97
423_G 427_N 1.138 0.97
151_N 232_M 1.129 0.97
212_N 215_W 1.124 0.97
129_G 132_I 1.124 0.97
414_G 418_I 1.119 0.96
434_G 437_K 1.115 0.96
425_S 429_T 1.112 0.96
48_C 179_M 1.109 0.96
218_V 222_A 1.106 0.96
59_N 63_I 1.1 0.96
61_N 72_L 1.099 0.96
75_L 128_F 1.099 0.96
433_V 437_K 1.098 0.96
302_A 305_V 1.094 0.96
253_H 256_L 1.092 0.96
323_F 446_C 1.085 0.96
244_D 247_P 1.085 0.96
74_L 420_Q 1.084 0.96
196_G 211_A 1.08 0.95
228_A 232_M 1.072 0.95
347_A 350_A 1.072 0.95
120_A 127_P 1.067 0.95
182_V 185_L 1.066 0.95
321_I 325_F 1.065 0.95
102_W 105_F 1.063 0.95
304_S 308_A 1.06 0.95
89_P 92_F 1.059 0.95
329_F 354_G 1.059 0.95
126_T 211_A 1.059 0.95
154_F 400_T 1.057 0.95
186_V 212_N 1.057 0.95
252_L 255_W 1.056 0.95
438_V 442_F 1.056 0.95
82_S 139_G 1.052 0.95
346_I 349_Y 1.051 0.94
70_D 427_N 1.043 0.94
290_R 294_F 1.039 0.94
94_V 99_G 1.039 0.94
364_G 368_Q 1.038 0.94
438_V 441_I 1.033 0.94
98_G 234_D 1.032 0.94
325_F 329_F 1.032 0.94
152_I 164_A 1.022 0.93
162_G 307_G 1.022 0.93
153_S 161_Q 1.021 0.93
320_L 451_W 1.02 0.93
99_G 234_D 1.019 0.93
249_L 255_W 1.018 0.93
188_F 286_V 1.018 0.93
299_G 360_G 1.014 0.93
42_C 144_N 1.012 0.93
119_I 215_W 1.009 0.93
350_A 353_M 1.004 0.93
328_I 332_L 1.003 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
1pw4A10.87881000.355Contact Map0.5
4j05A20.91561000.364Contact Map0.645
3wdoA10.83331000.369Contact Map0.643
4jr9A10.97621000.374Contact Map0.628
3o7qA10.88531000.389Contact Map0.622
2gfpA20.79221000.404Contact Map0.164
2cfqA10.83331000.422Contact Map0.522
4ldsA20.83771000.432Contact Map0.642
4gc0A10.85711000.438Contact Map0.728
2xutA30.85061000.438Contact Map0.527

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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