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YFCJ - UPF0226 protein YfcJ
UniProt: P77549 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14113
Length: 392 (366)
Sequences: 64414
Seq/Len: 175.99
YFCJ
Paralog alert: 0.90 [within 20: 0.65] - ratio of genomes with paralogs
Cluster includes: AMPG ARAE ARAJ BCR CYNX DGOT DTPA DTPB DTPD EMRB EMRD EMRY ENTS EXUT FSR FUCP GALP GARP GLPT GUDP HCAT HSRA KGTP LACY LPLT MDFA MDTD MDTG MDTH MDTL MDTM MELB MHPT NANT NARK NARU NEPI NUPG PROP RHMT SETA SETB SETC SHIA SOTB TSGA UHPC UHPT UIDB XAPB XYLE YAAU YAGG YAJR YBJJ YCAD YDEE YDFJ YDHC YDHP YDIM YDIN YDJE YDJK YEAN YEBQ YEGT YFCJ YGAY YGCS YHHS YHJE YHJX YICJ YIHN YIHO YIHP YJDL YJHB YJIJ YJJL YNFM YQCE
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
90_A 125_G 3.45 1.00
102_A 114_L 3.249 1.00
97_A 118_G 3.05 1.00
63_A 120_L 3.018 1.00
71_A 128_Q 2.877 1.00
99_L 182_I 2.861 1.00
80_A 139_G 2.848 1.00
92_G 188_P 2.846 1.00
94_A 118_G 2.832 1.00
111_K 114_L 2.796 1.00
113_A 117_V 2.776 1.00
331_V 339_A 2.67 1.00
141_V 149_V 2.582 1.00
112_F 116_V 2.557 1.00
147_G 274_D 2.501 1.00
87_G 128_Q 2.45 1.00
145_H 148_K 2.43 1.00
49_G 52_M 2.395 1.00
67_T 124_F 2.303 1.00
94_A 125_G 2.294 1.00
142_G 145_H 2.198 1.00
76_D 337_G 2.186 1.00
261_A 310_A 2.156 1.00
94_A 121_I 2.155 1.00
81_K 85_L 2.133 1.00
295_L 308_G 2.128 1.00
175_Y 179_A 2.089 1.00
265_M 314_A 2.03 1.00
288_V 315_G 2.007 1.00
332_P 335_V 1.973 1.00
278_G 329_K 1.956 1.00
52_M 112_F 1.915 1.00
48_Y 112_F 1.849 1.00
96_G 185_M 1.842 1.00
67_T 127_S 1.803 1.00
59_I 120_L 1.793 1.00
292_G 308_G 1.79 1.00
75_A 132_G 1.789 1.00
230_V 354_S 1.78 1.00
56_A 115_L 1.73 1.00
79_G 82_R 1.71 1.00
101_A 118_G 1.698 1.00
63_A 67_T 1.689 1.00
59_I 116_V 1.679 1.00
292_G 315_G 1.672 1.00
226_A 350_A 1.671 1.00
30_T 34_P 1.671 1.00
73_R 77_Q 1.668 1.00
101_A 114_L 1.661 1.00
234_V 358_A 1.659 1.00
372_L 376_I 1.645 1.00
285_S 318_L 1.63 1.00
290_T 382_I 1.625 1.00
94_A 122_L 1.622 1.00
85_L 192_W 1.605 1.00
48_Y 52_M 1.602 1.00
303_W 307_A 1.563 1.00
105_P 114_L 1.561 1.00
277_G 280_K 1.552 1.00
92_G 185_M 1.552 1.00
182_I 186_V 1.544 1.00
92_G 192_W 1.542 1.00
212_W 216_G 1.539 1.00
271_W 275_R 1.531 1.00
98_L 118_G 1.496 1.00
270_G 274_D 1.46 1.00
82_R 86_Q 1.448 1.00
72_G 76_D 1.443 1.00
258_F 313_G 1.439 1.00
114_L 118_G 1.438 1.00
176_G 179_A 1.436 1.00
148_K 274_D 1.435 1.00
74_L 83_S 1.431 1.00
74_L 78_Y 1.418 1.00
40_L 44_H 1.408 1.00
62_L 352_G 1.395 0.99
78_Y 83_S 1.395 0.99
143_P 146_S 1.394 0.99
261_A 265_M 1.391 0.99
89_L 192_W 1.388 0.99
102_A 111_K 1.38 0.99
137_G 153_N 1.359 0.99
67_T 70_Y 1.34 0.99
290_T 379_V 1.332 0.99
90_A 94_A 1.32 0.99
113_A 116_V 1.309 0.99
98_L 115_L 1.307 0.99
166_P 256_T 1.304 0.99
86_Q 90_A 1.301 0.99
87_G 125_G 1.299 0.99
272_M 276_F 1.293 0.99
99_L 185_M 1.291 0.99
222_G 346_F 1.286 0.99
179_A 182_I 1.271 0.99
138_L 146_S 1.269 0.99
297_W 372_L 1.267 0.99
92_G 189_V 1.262 0.99
287_L 291_V 1.261 0.99
268_M 271_W 1.26 0.99
30_T 33_L 1.259 0.99
82_R 85_L 1.257 0.99
37_V 172_H 1.257 0.99
97_A 100_L 1.255 0.99
70_Y 73_R 1.253 0.99
117_V 121_I 1.252 0.99
139_G 336_R 1.251 0.99
360_M 364_T 1.24 0.98
50_N 363_T 1.235 0.98
96_G 100_L 1.234 0.98
76_D 338_T 1.232 0.98
265_M 268_M 1.227 0.98
78_Y 82_R 1.216 0.98
21_A 156_A 1.215 0.98
290_T 294_L 1.203 0.98
250_M 253_F 1.196 0.98
83_S 86_Q 1.194 0.98
361_L 365_F 1.194 0.98
292_G 312_T 1.187 0.98
75_A 80_A 1.181 0.98
171_I 179_A 1.18 0.98
376_I 380_L 1.177 0.98
63_A 123_G 1.176 0.98
285_S 315_G 1.17 0.97
85_L 195_N 1.165 0.97
279_V 283_I 1.162 0.97
365_F 369_S 1.157 0.97
79_G 83_S 1.153 0.97
58_G 352_G 1.152 0.97
280_K 283_I 1.152 0.97
294_L 298_Q 1.144 0.97
350_A 354_S 1.134 0.97
327_V 343_Y 1.126 0.97
243_F 248_W 1.12 0.96
280_K 284_V 1.116 0.96
76_D 80_A 1.115 0.96
271_W 274_D 1.111 0.96
43_H 53_V 1.11 0.96
284_V 288_V 1.104 0.96
72_G 337_G 1.102 0.96
231_G 378_A 1.099 0.96
288_V 292_G 1.098 0.96
287_L 382_I 1.098 0.96
93_L 97_A 1.095 0.96
55_I 356_P 1.093 0.96
244_A 251_A 1.09 0.96
193_A 196_G 1.086 0.96
55_I 59_I 1.086 0.96
166_P 170_L 1.081 0.95
51_T 363_T 1.076 0.95
65_V 345_A 1.075 0.95
148_K 152_W 1.074 0.95
303_W 306_L 1.074 0.95
43_H 50_N 1.074 0.95
359_G 363_T 1.072 0.95
97_A 114_L 1.072 0.95
136_W 198_V 1.065 0.95
186_V 190_L 1.065 0.95
114_L 117_V 1.061 0.95
260_G 264_V 1.059 0.95
335_V 338_T 1.059 0.95
60_Q 126_E 1.057 0.95
292_G 311_L 1.054 0.95
146_S 329_K 1.049 0.94
30_T 35_L 1.045 0.94
276_F 281_V 1.044 0.94
283_I 382_I 1.043 0.94
294_L 375_A 1.042 0.94
290_T 375_A 1.041 0.94
170_L 174_H 1.041 0.94
161_L 259_G 1.036 0.94
269_F 318_L 1.029 0.94
54_G 58_G 1.021 0.93
40_L 45_E 1.014 0.93
99_L 178_A 1.013 0.93
59_I 63_A 1.012 0.93
307_A 311_L 1.007 0.93
85_L 89_L 1.005 0.93
167_L 170_L 1.004 0.93
189_V 193_A 1.003 0.93
119_R 123_G 1.002 0.92
185_M 189_V 1.001 0.92
45_E 178_A 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3wdoA10.95921000.185Contact Map0.642
1pw4A10.97451000.189Contact Map0.482
4j05A20.9771000.199Contact Map0.604
3o7qA10.96941000.208Contact Map0.656
2gfpA20.92351000.213Contact Map0.172
2xutA30.96941000.229Contact Map0.54
2cfqA10.97191000.231Contact Map0.508
4gc0A10.96941000.259Contact Map0.733
4lepA20.96941000.267Contact Map0.633
4apsA20.96941000.273Contact Map0.546
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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