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ENTS - Enterobactin exporter EntS
UniProt: P24077 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11104
Length: 416 (382)
Sequences: 67270
Seq/Len: 176.10
ENTS
Paralog alert: 0.91 [within 20: 0.66] - ratio of genomes with paralogs
Cluster includes: AMPG ARAE ARAJ BCR CYNX DGOT DTPA DTPB DTPD EMRB EMRD EMRY ENTS EXUT FSR FUCP GALP GARP GLPT GUDP HCAT HSRA KGTP LACY LPLT MDFA MDTD MDTG MDTH MDTL MDTM MELB MHPT NANT NARK NARU NEPI NUPG PROP RHMT SETA SETB SETC SHIA SOTB TSGA UHPC UHPT UIDB XAPB XYLE YAAU YAGG YAJR YBJJ YCAD YDEE YDFJ YDHC YDHP YDIM YDIN YDJE YDJK YEAN YEBQ YEGT YFCJ YGAY YGCS YHHS YHJE YHJX YICJ YIHN YIHO YIHP YJDL YJHB YJIJ YJJL YNFM YQCE
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
108_P 112_A 3.84 1.00
91_T 123_F 3.445 1.00
98_G 116_L 3.362 1.00
100_C 180_G 3.197 1.00
64_A 118_L 3.067 1.00
111_L 115_L 3.021 1.00
95_G 116_L 2.998 1.00
81_R 137_A 2.849 1.00
93_G 186_T 2.774 1.00
109_S 112_A 2.767 1.00
72_G 126_L 2.701 1.00
340_T 348_I 2.67 1.00
139_V 147_A 2.539 1.00
256_S 259_Q 2.457 1.00
110_L 114_Y 2.448 1.00
145_M 283_H 2.441 1.00
95_G 123_F 2.426 1.00
50_S 53_Q 2.409 1.00
88_A 126_L 2.336 1.00
68_G 122_F 2.32 1.00
77_D 346_G 2.272 1.00
143_N 146_Q 2.265 1.00
304_L 317_C 2.232 1.00
95_G 119_W 2.205 1.00
297_G 324_L 2.128 1.00
270_G 319_A 2.092 1.00
140_G 143_N 2.066 1.00
82_K 86_L 2.049 1.00
287_P 338_T 2.033 1.00
234_G 359_G 2.001 1.00
341_P 344_M 1.998 1.00
274_G 323_W 1.961 1.00
68_G 125_S 1.95 1.00
97_I 183_A 1.895 1.00
173_G 177_W 1.895 1.00
238_M 363_G 1.891 1.00
218_R 222_A 1.887 1.00
53_Q 110_L 1.85 1.00
312_I 316_V 1.807 1.00
60_L 118_L 1.805 1.00
381_S 385_F 1.788 1.00
76_A 130_A 1.788 1.00
93_G 190_L 1.788 1.00
49_H 110_L 1.779 1.00
301_A 317_C 1.762 1.00
107_E 112_A 1.756 1.00
60_L 114_Y 1.748 1.00
301_A 324_L 1.734 1.00
299_F 391_G 1.722 1.00
95_G 120_D 1.716 1.00
57_S 113_I 1.716 1.00
294_S 327_V 1.707 1.00
107_E 116_L 1.689 1.00
286_R 289_L 1.672 1.00
74_V 78_R 1.663 1.00
64_A 68_G 1.663 1.00
86_L 190_L 1.653 1.00
241_A 367_L 1.613 1.00
299_F 388_L 1.6 1.00
80_E 83_K 1.587 1.00
49_H 53_Q 1.58 1.00
90_G 190_L 1.577 1.00
280_K 284_S 1.556 1.00
99_L 116_L 1.541 1.00
93_G 183_A 1.531 1.00
255_M 259_Q 1.525 1.00
279_G 283_H 1.522 1.00
100_C 183_A 1.51 1.00
180_G 184_A 1.487 1.00
267_I 322_G 1.485 1.00
73_G 77_D 1.46 1.00
83_K 87_L 1.459 1.00
79_Y 84_V 1.444 1.00
75_L 84_V 1.438 1.00
230_A 355_Q 1.429 1.00
99_L 113_I 1.429 1.00
112_A 116_L 1.429 1.00
75_L 79_Y 1.393 0.99
310_M 313_L 1.393 0.99
174_G 177_W 1.381 0.99
270_G 274_G 1.377 0.99
296_L 391_G 1.375 0.99
141_R 144_L 1.367 0.99
259_Q 262_F 1.361 0.99
88_A 123_F 1.359 0.99
98_G 101_L 1.358 0.99
23_F 154_T 1.351 0.99
68_G 71_V 1.348 0.99
115_L 119_W 1.329 0.99
63_G 361_A 1.324 0.99
251_D 257_A 1.322 0.99
91_T 95_G 1.319 0.99
146_Q 283_H 1.311 0.99
42_V 45_Q 1.296 0.99
87_L 91_T 1.289 0.99
191_L 194_L 1.279 0.99
292_L 391_G 1.277 0.99
281_L 285_A 1.277 0.99
306_G 381_S 1.276 0.99
111_L 114_Y 1.276 0.99
97_I 101_L 1.273 0.99
137_A 345_L 1.264 0.99
296_L 300_L 1.26 0.99
177_W 180_G 1.259 0.99
136_P 144_L 1.256 0.99
51_T 372_A 1.255 0.99
135_T 151_T 1.254 0.99
83_K 86_L 1.252 0.99
79_Y 83_K 1.237 0.98
303_G 384_G 1.236 0.98
369_G 373_M 1.234 0.98
277_T 280_K 1.234 0.98
73_G 346_G 1.232 0.98
71_V 74_V 1.226 0.98
299_F 303_G 1.224 0.98
164_M 265_A 1.222 0.98
224_P 227_G 1.215 0.98
359_G 363_G 1.208 0.98
93_G 187_F 1.206 0.98
385_F 389_I 1.206 0.98
76_A 81_R 1.201 0.98
64_A 121_G 1.19 0.98
77_D 347_R 1.187 0.98
294_S 324_L 1.185 0.98
80_E 84_V 1.182 0.98
289_L 292_L 1.181 0.98
299_F 384_G 1.179 0.98
169_L 177_W 1.173 0.98
100_C 176_A 1.164 0.97
171_A 258_A 1.155 0.97
336_L 352_W 1.155 0.97
289_L 293_L 1.154 0.97
274_G 277_T 1.148 0.97
84_V 87_L 1.146 0.97
312_I 315_V 1.144 0.97
374_M 378_A 1.138 0.97
370_L 374_M 1.136 0.97
94_I 98_G 1.134 0.97
301_A 321_F 1.127 0.97
219_F 222_A 1.118 0.96
240_S 360_D 1.118 0.96
293_L 297_G 1.117 0.96
251_D 260_I 1.115 0.96
227_G 231_L 1.112 0.96
52_W 372_A 1.112 0.96
83_K 198_A 1.109 0.96
184_A 188_I 1.108 0.96
59_T 361_A 1.108 0.96
278_S 327_V 1.106 0.96
39_A 170_L 1.1 0.96
221_L 227_G 1.093 0.96
187_F 191_L 1.09 0.96
269_L 273_I 1.088 0.96
297_G 301_A 1.086 0.96
249_L 253_W 1.082 0.96
112_A 115_L 1.079 0.95
288_G 292_L 1.075 0.95
301_A 320_L 1.074 0.95
117_G 121_G 1.073 0.95
98_G 112_A 1.067 0.95
164_M 168_L 1.066 0.95
43_Q 175_V 1.064 0.95
368_G 372_A 1.063 0.95
30_I 155_V 1.062 0.95
144_L 338_T 1.053 0.95
44_I 54_V 1.051 0.94
86_L 193_L 1.048 0.94
27_F 158_G 1.046 0.94
56_L 60_L 1.045 0.94
294_S 328_S 1.044 0.94
77_D 81_R 1.044 0.94
167_G 261_G 1.041 0.94
192_P 195_S 1.041 0.94
101_L 180_G 1.039 0.94
146_Q 150_I 1.038 0.94
316_V 319_A 1.036 0.94
59_T 365_A 1.032 0.94
316_V 320_L 1.026 0.94
168_L 172_T 1.026 0.94
226_V 230_A 1.025 0.93
306_G 384_G 1.023 0.93
86_L 90_G 1.021 0.93
90_G 94_I 1.02 0.93
89_R 190_L 1.018 0.93
344_M 347_R 1.015 0.93
60_L 64_A 1.012 0.93
56_L 365_A 1.009 0.93
61_T 124_A 1.008 0.93
165_I 168_L 1.005 0.93
42_V 46_M 1.005 0.93
300_L 304_L 1.004 0.93
285_A 289_L 1.004 0.93
250_A 255_M 1.004 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3wdoA10.95911000.233Contact Map0.648
1pw4A10.99281000.241Contact Map0.489
4j05A20.98321000.249Contact Map0.621
2cfqA10.96631000.255Contact Map0.523
3o7qA10.94711000.27Contact Map0.637
2gfpA20.8871000.278Contact Map0.185
2xutA30.9761000.285Contact Map0.537
4ldsA20.96391000.298Contact Map0.634
4gc0A10.9881000.303Contact Map0.753
4apsA20.9761000.315Contact Map0.556
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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