May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
YJIJ - Uncharacterized protein YjiJ
UniProt: P39381 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12571
Length: 392 (368)
Sequences: 63586
Seq/Len: 172.79
YJIJ
Paralog alert: 0.90 [within 20: 0.66] - ratio of genomes with paralogs
Cluster includes: AMPG ARAE ARAJ BCR CYNX DGOT DTPA DTPB DTPD EMRB EMRD EMRY ENTS EXUT FSR FUCP GALP GARP GLPT GUDP HCAT HSRA KGTP LACY LPLT MDFA MDTD MDTG MDTH MDTL MDTM MELB MHPT NANT NARK NARU NEPI NUPG PROP RHMT SETA SETB SETC SHIA SOTB TSGA UHPC UHPT UIDB XAPB XYLE YAAU YAGG YAJR YBJJ YCAD YDEE YDFJ YDHC YDHP YDIM YDIN YDJE YDJK YEAN YEBQ YEGT YFCJ YGAY YGCS YHHS YHJE YHJX YICJ YIHN YIHO YIHP YJDL YJHB YJIJ YJJL YNFM YQCE
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
103_P 107_L 4.127 1.00
91_A 118_A 3.495 1.00
98_A 111_I 3.463 1.00
100_A 173_Q 3.244 1.00
106_I 110_L 3.004 1.00
62_G 113_V 2.926 1.00
93_G 179_S 2.844 1.00
95_L 111_I 2.823 1.00
70_F 121_G 2.791 1.00
81_L 132_Q 2.774 1.00
104_P 107_L 2.74 1.00
105_F 109_L 2.504 1.00
137_P 269_K 2.497 1.00
135_R 138_F 2.468 1.00
88_S 121_G 2.456 1.00
48_S 51_Q 2.346 1.00
326_S 333_L 2.267 1.00
66_G 117_V 2.252 1.00
95_L 114_L 2.239 1.00
82_R 86_L 2.232 1.00
95_L 118_A 2.222 1.00
290_L 303_S 2.18 1.00
256_S 305_L 2.152 1.00
283_V 310_T 2.136 1.00
260_G 309_G 2.078 1.00
220_G 344_G 2.045 1.00
166_L 170_T 2.041 1.00
75_F 331_L 2.003 1.00
224_F 348_G 1.974 1.00
102_L 107_L 1.974 1.00
102_L 111_I 1.875 1.00
51_Q 105_F 1.855 1.00
97_L 176_G 1.836 1.00
287_C 303_S 1.825 1.00
86_L 183_L 1.822 1.00
47_F 105_F 1.813 1.00
273_A 324_Q 1.802 1.00
86_L 187_T 1.797 1.00
228_I 352_T 1.792 1.00
93_G 183_L 1.787 1.00
58_G 113_V 1.778 1.00
55_I 108_V 1.768 1.00
74_A 125_F 1.761 1.00
66_G 120_A 1.757 1.00
72_F 76_H 1.754 1.00
287_C 310_T 1.732 1.00
58_G 109_L 1.702 1.00
298_L 302_I 1.698 1.00
184_I 188_L 1.681 1.00
99_M 111_I 1.679 1.00
95_L 115_A 1.663 1.00
367_L 371_A 1.657 1.00
90_L 183_L 1.628 1.00
62_G 66_G 1.624 1.00
280_N 313_G 1.611 1.00
78_P 83_P 1.609 1.00
272_G 275_P 1.604 1.00
47_F 51_Q 1.584 1.00
99_M 108_V 1.575 1.00
266_W 270_R 1.546 1.00
83_P 87_A 1.517 1.00
265_L 269_K 1.504 1.00
40_V 43_A 1.483 1.00
71_S 75_F 1.476 1.00
138_F 269_K 1.467 1.00
173_Q 177_A 1.451 1.00
93_G 176_G 1.442 1.00
21_L 146_G 1.439 1.00
100_A 176_G 1.439 1.00
167_S 170_T 1.439 1.00
216_A 340_I 1.437 1.00
185_A 189_L 1.435 1.00
285_A 377_A 1.432 1.00
107_L 111_I 1.421 1.00
253_V 308_G 1.415 1.00
73_G 84_F 1.411 1.00
256_S 260_G 1.404 0.99
97_L 101_W 1.38 0.99
73_G 77_Q 1.368 0.99
61_A 346_I 1.368 0.99
91_A 95_L 1.368 0.99
77_Q 84_F 1.363 0.99
245_L 248_H 1.356 0.99
87_A 91_A 1.354 0.99
66_G 69_L 1.35 0.99
98_A 101_W 1.349 0.99
242_S 245_L 1.345 0.99
110_L 114_L 1.334 0.99
74_A 81_L 1.314 0.99
267_A 271_W 1.298 0.99
106_I 109_L 1.294 0.99
83_P 86_L 1.282 0.99
263_G 266_W 1.273 0.99
238_K 246_T 1.259 0.99
354_M 358_G 1.252 0.99
69_L 72_F 1.252 0.99
156_E 251_T 1.246 0.98
130_I 143_L 1.236 0.98
260_G 263_G 1.236 0.98
93_G 180_G 1.228 0.98
170_T 173_Q 1.222 0.98
238_K 243_P 1.222 0.98
282_L 286_I 1.219 0.98
62_G 116_G 1.218 0.98
84_F 87_A 1.212 0.98
131_M 136_H 1.208 0.98
42_M 52_L 1.204 0.98
344_G 348_G 1.2 0.98
285_A 374_F 1.198 0.98
77_Q 83_P 1.197 0.98
355_L 359_T 1.197 0.98
285_A 289_L 1.186 0.98
49_F 357_N 1.184 0.98
100_A 169_Q 1.18 0.98
274_L 278_T 1.178 0.98
40_V 44_E 1.176 0.98
287_C 307_F 1.175 0.98
75_F 81_L 1.17 0.97
296_S 299_L 1.158 0.97
129_L 190_M 1.155 0.97
177_A 181_M 1.154 0.97
75_F 332_N 1.151 0.97
275_P 278_T 1.148 0.97
289_L 370_A 1.147 0.97
28_G 147_V 1.138 0.97
282_L 377_A 1.138 0.97
225_G 373_L 1.132 0.97
64_L 339_L 1.129 0.97
88_S 118_A 1.128 0.97
275_P 279_A 1.127 0.97
298_L 301_I 1.121 0.97
287_C 306_G 1.12 0.96
209_I 213_W 1.119 0.96
107_L 110_L 1.118 0.96
98_A 107_L 1.118 0.96
57_S 346_I 1.116 0.96
227_I 345_Q 1.113 0.96
54_W 58_G 1.112 0.96
133_H 136_H 1.105 0.96
59_N 119_S 1.104 0.96
94_L 98_A 1.103 0.96
213_W 217_I 1.098 0.96
101_W 173_Q 1.093 0.96
161_G 170_T 1.092 0.96
54_W 350_A 1.086 0.96
264_W 313_G 1.085 0.96
280_N 310_T 1.085 0.96
50_S 357_N 1.082 0.96
371_A 375_I 1.076 0.95
151_I 254_G 1.07 0.95
25_L 150_G 1.068 0.95
279_A 283_V 1.066 0.95
280_N 314_T 1.065 0.95
266_W 269_K 1.063 0.95
156_E 160_A 1.063 0.95
368_C 372_A 1.063 0.95
59_N 63_Y 1.061 0.95
292_L 367_L 1.061 0.95
255_L 259_P 1.059 0.95
322_A 337_V 1.058 0.95
59_N 116_G 1.054 0.95
37_M 171_L 1.051 0.94
83_P 192_S 1.047 0.94
53_S 57_S 1.037 0.94
112_R 116_G 1.037 0.94
212_W 216_A 1.037 0.94
237_A 242_S 1.032 0.94
186_L 190_M 1.031 0.94
289_L 293_A 1.031 0.94
86_L 90_L 1.026 0.94
259_P 263_G 1.026 0.94
44_E 169_Q 1.026 0.94
138_F 142_A 1.025 0.93
285_A 370_A 1.025 0.93
244_L 248_H 1.02 0.93
81_L 192_S 1.02 0.93
278_T 377_A 1.019 0.93
23_L 122_M 1.019 0.93
222_A 314_T 1.016 0.93
210_M 213_W 1.013 0.93
292_L 370_A 1.013 0.93
363_A 367_L 1.013 0.93
138_F 266_W 1.013 0.93
353_S 357_N 1.008 0.93
57_S 350_A 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1pw4A10.98471000.191Contact Map0.494
3wdoA10.97191000.208Contact Map0.627
4j05A20.98471000.209Contact Map0.637
2gfpA20.9261000.219Contact Map0.181
3o7qA10.9771000.225Contact Map0.625
2cfqA10.96681000.227Contact Map0.491
2xutA30.98211000.259Contact Map0.537
4gc0A10.98211000.259Contact Map0.694
4ldsA20.96681000.262Contact Map0.652
4apsA20.98211000.305Contact Map0.559
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 1.4983 seconds.