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YDJK - Putative metabolite transport protein YdjK
UniProt: P76230 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13487
Length: 459 (431)
Sequences: 48080
Seq/Len: 111.55
YDJK
Paralog alert: 0.89 [within 20: 0.55] - ratio of genomes with paralogs
Cluster includes: AMPG ARAE ARAJ BCR CYNX DGOT DTPA DTPB DTPD EMRB EMRD EMRY ENTS EXUT FSR FUCP GALP GARP GLPT GUDP HCAT HSRA KGTP LACY LPLT MDFA MDTD MDTG MDTH MDTL MDTM MELB MHPT NANT NARK NARU NEPI NUPG PROP RHMT SETA SETB SETC SHIA SOTB TSGA UHPC UHPT UIDB XAPB XYLE YAAU YAGG YAJR YBJJ YCAD YDEE YDFJ YDHC YDHP YDIM YDIN YDJE YDJK YEAN YEBQ YEGT YFCJ YGAY YGCS YHHS YHJE YHJX YICJ YIHN YIHO YIHP YJDL YJHB YJIJ YJJL YNFM YQCE
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
109_P 113_F 4.799 1.00
97_I 124_G 3.763 1.00
106_A 185_L 3.507 1.00
112_D 116_A 3.487 1.00
104_V 117_C 3.362 1.00
99_I 191_S 3.178 1.00
70_G 119_F 3.174 1.00
101_S 117_C 3.09 1.00
110_N 113_F 3.021 1.00
111_M 115_I 2.96 1.00
78_G 127_A 2.906 1.00
146_G 324_D 2.9 1.00
214_R 217_E 2.746 1.00
382_W 390_G 2.745 1.00
297_N 300_D 2.641 1.00
87_R 138_E 2.55 1.00
94_Y 127_A 2.545 1.00
83_D 388_L 2.499 1.00
101_S 120_V 2.476 1.00
423_I 427_A 2.459 1.00
140_M 148_W 2.435 1.00
74_G 123_V 2.342 1.00
101_S 124_G 2.334 1.00
144_N 147_T 2.319 1.00
141_P 144_N 2.171 1.00
108_S 113_F 2.171 1.00
274_I 401_S 2.156 1.00
66_I 119_F 2.088 1.00
108_S 117_C 2.073 1.00
383_P 386_A 2.064 1.00
74_G 126_G 2.035 1.00
88_R 92_I 1.994 1.00
66_I 115_I 1.97 1.00
101_S 121_M 1.968 1.00
55_T 59_T 1.956 1.00
80_I 84_K 1.953 1.00
92_I 195_T 1.951 1.00
328_R 380_E 1.936 1.00
63_F 114_L 1.905 1.00
103_V 188_A 1.904 1.00
92_I 199_W 1.894 1.00
278_V 405_A 1.88 1.00
99_I 195_T 1.878 1.00
96_A 195_T 1.874 1.00
178_W 182_V 1.853 1.00
81_I 90_A 1.831 1.00
82_G 131_T 1.811 1.00
255_S 259_T 1.804 1.00
105_G 117_C 1.75 1.00
327_P 330_T 1.743 1.00
59_T 111_M 1.72 1.00
104_V 107_F 1.714 1.00
311_G 361_F 1.693 1.00
103_V 107_F 1.673 1.00
315_G 365_F 1.671 1.00
86_G 89_N 1.643 1.00
89_N 93_L 1.636 1.00
79_G 83_D 1.632 1.00
85_T 90_A 1.625 1.00
54_W 111_M 1.625 1.00
105_G 114_L 1.618 1.00
321_L 325_K 1.615 1.00
320_M 324_D 1.603 1.00
70_G 74_G 1.582 1.00
354_L 358_I 1.58 1.00
116_A 120_V 1.558 1.00
113_F 117_C 1.553 1.00
147_T 324_D 1.548 1.00
216_Q 219_E 1.545 1.00
74_G 77_V 1.538 1.00
282_T 409_V 1.534 1.00
196_A 200_R 1.533 1.00
69_A 403_I 1.531 1.00
97_I 101_S 1.52 1.00
65_A 403_I 1.488 1.00
85_T 89_N 1.476 1.00
338_L 366_V 1.475 1.00
179_N 182_V 1.462 1.00
81_I 85_T 1.455 1.00
54_W 59_T 1.443 1.00
411_V 415_S 1.418 1.00
99_I 188_A 1.415 1.00
427_A 431_I 1.409 1.00
106_A 188_A 1.404 0.99
93_L 97_I 1.367 0.99
89_N 92_I 1.362 0.99
311_G 315_G 1.353 0.99
79_G 388_L 1.332 0.99
300_D 303_V 1.326 0.99
106_A 181_R 1.323 0.99
198_A 202_F 1.32 0.99
318_I 321_L 1.318 0.99
72_F 396_A 1.313 0.99
322_V 326_I 1.308 0.99
292_M 301_S 1.307 0.99
112_D 115_I 1.307 0.99
412_L 416_Y 1.306 0.99
333_V 433_A 1.302 0.99
342_L 366_V 1.298 0.99
340_A 433_A 1.297 0.99
256_A 386_A 1.297 0.99
142_G 145_R 1.296 0.99
109_P 181_R 1.296 0.99
185_L 189_I 1.285 0.99
70_G 122_G 1.284 0.99
401_S 405_A 1.282 0.99
296_I 300_D 1.282 0.99
406_P 410_A 1.28 0.99
270_S 397_V 1.275 0.99
340_A 430_I 1.275 0.99
138_E 387_K 1.273 0.99
86_G 204_E 1.267 0.99
22_H 144_N 1.267 0.99
310_F 314_F 1.267 0.99
308_S 364_T 1.265 0.99
279_V 429_S 1.263 0.99
89_N 204_E 1.256 0.99
82_G 87_R 1.255 0.99
342_L 359_G 1.254 0.99
338_L 342_L 1.243 0.98
83_D 389_R 1.241 0.98
197_L 201_Y 1.239 0.98
182_V 185_L 1.235 0.98
340_A 426_G 1.234 0.98
430_I 434_I 1.23 0.98
30_A 155_I 1.23 0.98
410_A 414_S 1.23 0.98
113_F 116_A 1.228 0.98
337_I 341_V 1.226 0.98
94_Y 124_G 1.222 0.98
100_A 104_V 1.221 0.98
215_Y 219_E 1.221 0.98
57_N 414_S 1.218 0.98
87_R 204_E 1.215 0.98
261_V 264_K 1.212 0.98
187_P 190_L 1.206 0.98
420_G 423_I 1.205 0.98
420_G 424_L 1.204 0.98
136_F 152_V 1.193 0.98
104_V 113_F 1.192 0.98
292_M 298_L 1.191 0.98
260_G 263_L 1.189 0.98
163_C 168_M 1.185 0.98
67_T 125_L 1.184 0.98
345_I 359_G 1.176 0.98
281_Y 402_G 1.171 0.98
269_G 394_A 1.171 0.98
83_D 87_R 1.168 0.97
219_E 223_R 1.168 0.97
90_A 93_L 1.162 0.97
86_G 90_A 1.156 0.97
189_I 193_I 1.149 0.97
424_L 427_A 1.146 0.97
424_L 428_V 1.144 0.97
261_V 265_R 1.139 0.97
416_Y 420_G 1.138 0.97
147_T 151_R 1.138 0.97
63_F 111_M 1.135 0.97
315_G 318_I 1.129 0.97
275_A 432_V 1.129 0.97
165_L 169_G 1.126 0.97
61_A 65_A 1.123 0.97
342_L 363_I 1.123 0.97
327_P 331_M 1.115 0.96
192_L 196_A 1.111 0.96
446_V 450_S 1.111 0.96
136_F 148_W 1.108 0.96
419_T 423_I 1.103 0.96
290_I 294_Q 1.102 0.96
256_A 259_T 1.1 0.96
99_I 192_L 1.097 0.96
408_A 411_V 1.096 0.96
337_I 433_A 1.091 0.96
137_T 145_R 1.086 0.96
146_G 320_M 1.084 0.96
135_G 202_F 1.082 0.96
91_F 135_G 1.077 0.95
145_R 380_E 1.073 0.95
317_F 321_L 1.072 0.95
188_A 192_L 1.071 0.95
95_E 195_T 1.067 0.95
92_I 96_A 1.064 0.95
291_F 294_Q 1.062 0.95
182_V 186_I 1.062 0.95
147_T 321_L 1.062 0.95
286_W 410_A 1.059 0.95
329_K 333_V 1.05 0.94
277_N 280_Q 1.05 0.94
291_F 296_I 1.049 0.94
71_M 399_R 1.049 0.94
234_G 237_L 1.043 0.94
51_A 181_R 1.032 0.94
330_T 334_G 1.032 0.94
118_R 122_G 1.028 0.94
335_L 366_V 1.028 0.94
58_S 414_S 1.026 0.94
67_T 71_M 1.026 0.94
62_T 66_I 1.025 0.93
326_I 331_M 1.02 0.93
72_F 403_I 1.016 0.93
377_Y 440_G 1.015 0.93
400_I 404_A 1.007 0.93
187_P 191_S 1.007 0.93
263_L 267_I 1.005 0.93
210_E 215_Y 1.002 0.92
270_S 393_L 1.002 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4j05A20.99351000.285Contact Map0.616
4gc0A10.95641000.295Contact Map0.696
1pw4A10.93251000.309Contact Map0.46
4ldsA20.93681000.319Contact Map0.631
3wdoA10.87151000.341Contact Map0.623
3o7qA10.88451000.376Contact Map0.623
2gfpA20.80611000.386Contact Map0.173
2cfqA10.87361000.387Contact Map0.447
2xutA30.95641000.398Contact Map0.517
4lepA20.9631000.428Contact Map0.577
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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