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OPENSEQ.org
YEBQ - Uncharacterized transporter YebQ
UniProt: P76269 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14019
Length: 457 (434)
Sequences: 60802
Seq/Len: 140.10
YEBQ
Paralog alert: 0.90 [within 20: 0.61] - ratio of genomes with paralogs
Cluster includes: AMPG ARAE ARAJ BCR CYNX DGOT DTPA DTPB DTPD EMRB EMRD EMRY ENTS EXUT FSR FUCP GALP GARP GLPT GUDP HCAT HSRA KGTP LACY LPLT MDFA MDTD MDTG MDTH MDTL MDTM MELB MHPT NANT NARK NARU NEPI NUPG PROP RHMT SETA SETB SETC SHIA SOTB TSGA UHPC UHPT UIDB XAPB XYLE YAAU YAGG YAJR YBJJ YCAD YDEE YDFJ YDHC YDHP YDIM YDIN YDJE YDJK YEAN YEBQ YEGT YFCJ YGAY YGCS YHHS YHJE YHJX YICJ YIHN YIHO YIHP YJDL YJHB YJIJ YJJL YNFM YQCE
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
102_D 106_M 4.378 1.00
90_V 117_G 3.635 1.00
97_F 110_A 3.427 1.00
99_A 174_L 3.391 1.00
105_Q 109_L 3.061 1.00
92_L 180_G 3.042 1.00
94_S 110_A 3.018 1.00
63_A 112_V 2.938 1.00
103_S 106_M 2.773 1.00
80_Y 131_L 2.747 1.00
71_F 120_A 2.71 1.00
104_L 108_T 2.611 1.00
302_S 305_E 2.584 1.00
139_G 329_E 2.567 1.00
389_A 397_A 2.558 1.00
49_T 52_S 2.438 1.00
94_S 117_G 2.429 1.00
87_G 120_A 2.427 1.00
137_F 140_R 2.352 1.00
133_Y 141_G 2.328 1.00
278_V 408_G 2.315 1.00
76_D 395_G 2.285 1.00
343_I 373_G 2.276 1.00
67_S 116_F 2.274 1.00
320_M 372_A 2.232 1.00
316_A 368_I 2.21 1.00
282_C 412_G 2.188 1.00
94_S 113_I 2.188 1.00
202_R 205_L 2.148 1.00
134_P 137_F 2.14 1.00
390_P 393_R 2.087 1.00
350_S 366_P 2.07 1.00
96_L 177_V 2.062 1.00
101_S 106_M 2.035 1.00
81_R 85_K 2.015 1.00
347_G 366_P 2.008 1.00
167_A 171_W 1.982 1.00
101_S 110_A 1.979 1.00
67_S 119_A 1.955 1.00
85_K 184_L 1.896 1.00
92_L 184_L 1.892 1.00
262_V 266_R 1.875 1.00
85_K 188_M 1.852 1.00
59_A 108_T 1.802 1.00
75_G 124_V 1.775 1.00
59_A 112_V 1.772 1.00
94_S 114_Q 1.763 1.00
52_S 104_L 1.761 1.00
48_A 104_L 1.749 1.00
286_L 416_V 1.743 1.00
98_C 110_A 1.732 1.00
347_G 373_G 1.726 1.00
433_M 437_I 1.72 1.00
333_A 387_T 1.705 1.00
63_A 67_S 1.694 1.00
361_I 365_W 1.688 1.00
56_V 107_L 1.686 1.00
73_F 77_M 1.671 1.00
89_V 184_L 1.665 1.00
22_V 148_I 1.664 1.00
345_A 443_A 1.655 1.00
185_L 189_R 1.644 1.00
345_A 440_V 1.629 1.00
98_C 107_L 1.615 1.00
74_L 83_I 1.6 1.00
332_H 335_L 1.599 1.00
79_G 82_R 1.573 1.00
48_A 52_S 1.572 1.00
92_L 177_V 1.564 1.00
14_R 137_F 1.548 1.00
96_L 100_L 1.527 1.00
72_S 76_D 1.524 1.00
326_Y 330_R 1.508 1.00
296_Q 306_T 1.506 1.00
325_G 329_E 1.504 1.00
263_D 266_R 1.494 1.00
97_F 100_L 1.487 1.00
274_I 404_A 1.479 1.00
168_S 171_W 1.476 1.00
62_I 410_S 1.473 1.00
316_A 320_M 1.46 1.00
340_G 376_L 1.458 1.00
106_M 110_A 1.457 1.00
82_R 86_C 1.451 1.00
74_L 78_F 1.444 1.00
301_R 305_E 1.432 1.00
78_F 83_I 1.425 1.00
174_L 178_P 1.413 1.00
263_D 393_R 1.41 1.00
86_C 90_V 1.4 0.99
99_A 177_V 1.398 0.99
349_F 436_A 1.388 0.99
140_R 329_E 1.381 0.99
135_Q 138_L 1.378 0.99
313_W 371_G 1.371 0.99
383_H 387_T 1.35 0.99
67_S 70_S 1.341 0.99
345_A 349_F 1.334 0.99
90_V 94_S 1.326 0.99
345_A 436_A 1.318 0.99
305_E 308_L 1.317 0.99
41_T 44_T 1.314 0.99
163_I 171_W 1.307 0.99
342_F 443_A 1.304 0.99
105_Q 108_T 1.3 0.99
347_G 370_C 1.297 0.99
29_V 149_V 1.288 0.99
342_F 346_A 1.284 0.99
294_Y 299_L 1.283 0.99
87_G 117_G 1.274 0.99
338_A 443_A 1.271 0.99
109_L 113_I 1.269 0.99
296_Q 303_E 1.257 0.99
129_I 145_N 1.248 0.99
63_A 115_G 1.234 0.98
340_G 377_F 1.232 0.98
158_T 311_T 1.231 0.98
210_M 251_R 1.23 0.98
130_R 138_L 1.229 0.98
352_V 433_M 1.225 0.98
60_Y 64_I 1.225 0.98
334_G 338_A 1.224 0.98
327_L 331_V 1.223 0.98
82_R 85_K 1.222 0.98
323_L 326_Y 1.219 0.98
171_W 174_L 1.212 0.98
340_G 373_G 1.208 0.98
24_G 121_L 1.206 0.98
92_L 181_I 1.202 0.98
58_N 410_S 1.199 0.98
43_A 53_S 1.199 0.98
408_G 412_G 1.198 0.98
83_I 86_C 1.197 0.98
234_I 238_L 1.196 0.98
270_F 274_I 1.194 0.98
99_A 170_K 1.19 0.98
75_G 80_Y 1.187 0.98
76_D 396_G 1.185 0.98
187_A 191_L 1.183 0.98
418_L 422_Q 1.183 0.98
186_L 190_F 1.182 0.98
128_L 191_L 1.179 0.98
320_M 323_L 1.178 0.98
60_Y 118_G 1.174 0.98
285_M 409_Q 1.169 0.97
51_A 421_N 1.166 0.97
437_I 441_I 1.164 0.97
38_A 164_L 1.158 0.97
76_D 80_Y 1.156 0.97
265_L 271_S 1.154 0.97
65_V 403_T 1.154 0.97
93_L 97_F 1.148 0.97
165_S 304_V 1.145 0.97
97_F 106_M 1.144 0.97
214_T 244_V 1.137 0.97
78_F 82_R 1.137 0.97
335_L 339_L 1.136 0.97
335_L 338_A 1.134 0.97
359_A 362_N 1.132 0.97
50_P 421_N 1.127 0.97
72_S 395_G 1.126 0.97
82_R 193_P 1.125 0.97
324_A 376_L 1.124 0.97
79_G 83_I 1.117 0.96
339_L 343_I 1.116 0.96
100_L 174_L 1.113 0.96
315_L 319_V 1.109 0.96
30_L 176_N 1.099 0.96
347_G 369_L 1.093 0.96
159_I 162_A 1.091 0.96
178_P 182_I 1.088 0.96
41_T 45_D 1.085 0.96
26_S 152_S 1.085 0.96
419_M 423_F 1.083 0.96
88_L 184_L 1.083 0.96
417_A 421_N 1.08 0.95
271_S 275_C 1.079 0.95
131_L 394_S 1.078 0.95
283_A 439_A 1.074 0.95
140_R 144_I 1.072 0.95
106_M 109_L 1.06 0.95
70_S 73_F 1.058 0.95
58_N 414_A 1.057 0.95
204_D 207_S 1.056 0.95
268_P 272_L 1.056 0.95
277_S 401_L 1.053 0.95
181_I 185_L 1.053 0.95
295_L 301_R 1.046 0.94
361_I 364_I 1.045 0.94
60_Y 115_G 1.045 0.94
317_T 375_G 1.039 0.94
430_V 434_A 1.038 0.94
102_D 170_K 1.038 0.94
308_L 312_P 1.038 0.94
45_D 170_K 1.036 0.94
55_W 59_A 1.032 0.94
177_V 181_I 1.032 0.94
80_Y 193_P 1.026 0.94
280_S 377_F 1.025 0.93
81_R 193_P 1.023 0.93
85_K 89_V 1.022 0.93
111_R 115_G 1.022 0.93
18_I 133_Y 1.021 0.93
235_A 239_V 1.019 0.93
301_R 309_L 1.019 0.93
161_A 307_G 1.017 0.93
162_A 166_I 1.015 0.93
30_L 156_G 1.011 0.93
158_T 162_A 1.007 0.93
331_V 336_L 1.004 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1pw4A10.9191000.257Contact Map0.491
4j05A20.96721000.279Contact Map0.615
3wdoA10.85561000.296Contact Map0.643
4gc0A10.931000.296Contact Map0.717
2gfpA20.82061000.307Contact Map0.172
3o7qA10.86871000.312Contact Map0.626
4ldsA20.91471000.314Contact Map0.635
2cfqA10.86211000.326Contact Map0.508
2xutA30.99121000.336Contact Map0.538
4jr9A10.861000.357Contact Map0.615
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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