| UniProt: | Q46791 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13041 | ||
| Length: | 210 (202) | ||
| Sequences: | 30161 | ||
| Seq/Len: | 149.31 |
| YGEK
Paralog alert: 0.94 [within 20: 0.58] - ratio of genomes with paralogs Cluster includes: ARCA BAER BASR BGLJ CPXR CREB CSGD CUSR DCUR DPIA EVGA FIMZ KDPE NARL NARP OMPR PHOB PHOP QSEB RCSB RSTA TORR UHPA UVRY YEDW YGEK YHJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 16_I | 35_G | 3.634 | 1.00 | |
| 16_I | 37_K | 2.989 | 1.00 | |
| 40_K | 62_G | 2.655 | 1.00 | |
| 20_I | 35_G | 2.611 | 1.00 | |
| 38_D | 62_G | 2.454 | 1.00 | |
| 11_Q | 42_A | 2.441 | 1.00 | |
| 165_N | 180_E | 2.426 | 1.00 | |
| 151_R | 154_E | 2.4 | 1.00 | |
| 177_K | 180_E | 2.35 | 1.00 | |
| 63_M | 71_W | 2.336 | 1.00 | |
| 20_I | 24_G | 2.27 | 1.00 | |
| 93_S | 113_K | 2.264 | 1.00 | |
| 90_Y | 110_H | 2.254 | 1.00 | |
| 39_L | 63_M | 2.223 | 1.00 | |
| 152_E | 189_K | 2.149 | 1.00 | |
| 38_D | 41_K | 2.104 | 1.00 | |
| 22_F | 111_P | 2.067 | 1.00 | |
| 47_N | 75_H | 2.021 | 1.00 | |
| 43_I | 71_W | 1.99 | 1.00 | |
| 7_V | 31_E | 1.95 | 1.00 | |
| 64_M | 67_E | 1.927 | 1.00 | |
| 182_H | 185_N | 1.87 | 1.00 | |
| 36_Y | 45_E | 1.857 | 1.00 | |
| 37_K | 41_K | 1.833 | 1.00 | |
| 157_Q | 161_D | 1.821 | 1.00 | |
| 69_V | 81_I | 1.744 | 1.00 | |
| 53_I | 118_I | 1.719 | 1.00 | |
| 136_E | 142_Y | 1.719 | 1.00 | |
| 83_T | 96_L | 1.718 | 1.00 | |
| 56_L | 68_L | 1.708 | 1.00 | |
| 23_L | 118_I | 1.704 | 1.00 | |
| 82_I | 121_I | 1.68 | 1.00 | |
| 98_E | 119_D | 1.653 | 1.00 | |
| 58_E | 83_T | 1.652 | 1.00 | |
| 59_F | 87_K | 1.628 | 1.00 | |
| 56_L | 69_V | 1.608 | 1.00 | |
| 9_S | 36_Y | 1.567 | 1.00 | |
| 34_G | 51_A | 1.565 | 1.00 | |
| 158_L | 168_I | 1.548 | 1.00 | |
| 102_K | 124_G | 1.539 | 1.00 | |
| 83_T | 101_A | 1.539 | 1.00 | |
| 69_V | 83_T | 1.531 | 1.00 | |
| 71_W | 74_S | 1.524 | 1.00 | |
| 164_T | 167_E | 1.518 | 1.00 | |
| 33_V | 51_A | 1.507 | 1.00 | |
| 12_Q | 16_I | 1.477 | 1.00 | |
| 158_L | 171_F | 1.475 | 1.00 | |
| 87_K | 92_D | 1.456 | 1.00 | |
| 11_Q | 60_A | 1.437 | 1.00 | |
| 192_V | 201_T | 1.424 | 1.00 | |
| 63_M | 67_E | 1.419 | 1.00 | |
| 54_F | 79_A | 1.408 | 1.00 | |
| 39_L | 68_L | 1.406 | 0.99 | |
| 43_I | 68_L | 1.387 | 0.99 | |
| 163_K | 171_F | 1.377 | 0.99 | |
| 103_G | 117_A | 1.373 | 0.99 | |
| 73_K | 102_K | 1.369 | 0.99 | |
| 66_A | 99_A | 1.349 | 0.99 | |
| 26_Y | 115_N | 1.314 | 0.99 | |
| 40_K | 63_M | 1.271 | 0.99 | |
| 58_E | 66_A | 1.27 | 0.99 | |
| 71_W | 75_H | 1.268 | 0.99 | |
| 45_E | 49_S | 1.264 | 0.99 | |
| 7_V | 33_V | 1.264 | 0.99 | |
| 44_A | 48_K | 1.256 | 0.99 | |
| 67_E | 70_K | 1.25 | 0.99 | |
| 28_D | 119_D | 1.237 | 0.98 | |
| 158_L | 163_K | 1.225 | 0.98 | |
| 40_K | 44_A | 1.222 | 0.98 | |
| 43_I | 63_M | 1.22 | 0.98 | |
| 178_T | 182_H | 1.215 | 0.98 | |
| 45_E | 48_K | 1.202 | 0.98 | |
| 149_T | 189_K | 1.198 | 0.98 | |
| 183_R | 187_M | 1.189 | 0.98 | |
| 30_Y | 119_D | 1.188 | 0.98 | |
| 89_P | 92_D | 1.183 | 0.98 | |
| 46_C | 72_V | 1.178 | 0.98 | |
| 181_T | 184_L | 1.171 | 0.98 | |
| 36_Y | 42_A | 1.17 | 0.97 | |
| 70_K | 95_K | 1.162 | 0.97 | |
| 53_I | 122_S | 1.131 | 0.97 | |
| 166_K | 176_R | 1.129 | 0.97 | |
| 201_T | 205_M | 1.127 | 0.97 | |
| 34_G | 49_S | 1.12 | 0.96 | |
| 26_Y | 119_D | 1.118 | 0.96 | |
| 13_P | 57_G | 1.117 | 0.96 | |
| 42_A | 46_C | 1.097 | 0.96 | |
| 8_V | 30_Y | 1.093 | 0.96 | |
| 91_I | 95_K | 1.093 | 0.96 | |
| 166_K | 170_N | 1.084 | 0.96 | |
| 156_L | 198_L | 1.08 | 0.95 | |
| 19_I | 84_F | 1.073 | 0.95 | |
| 41_K | 44_A | 1.071 | 0.95 | |
| 140_S | 157_Q | 1.062 | 0.95 | |
| 66_A | 95_K | 1.058 | 0.95 | |
| 11_Q | 54_F | 1.056 | 0.95 | |
| 41_K | 45_E | 1.051 | 0.94 | |
| 9_S | 42_A | 1.038 | 0.94 | |
| 121_I | 124_G | 1.036 | 0.94 | |
| 60_A | 68_L | 1.035 | 0.94 | |
| 59_F | 86_A | 1.035 | 0.94 | |
| 134_D | 138_I | 1.033 | 0.94 | |
| 12_Q | 60_A | 1.032 | 0.94 | |
| 163_K | 167_E | 1.027 | 0.94 | |
| 154_E | 157_Q | 1.015 | 0.93 | |
| 120_S | 125_Y | 1.007 | 0.93 | |
| 45_E | 51_A | 1.002 | 0.92 | |
| 177_K | 181_T | 1.001 | 0.92 | |
| 19_I | 114_L | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3c3wA | 2 | 0.9714 | 100 | 0.085 | Contact Map | 0.627 |
| 4gvpA | 4 | 0.9667 | 100 | 0.096 | Contact Map | 0.815 |
| 4hyeA | 2 | 0.9619 | 100 | 0.109 | Contact Map | 0.819 |
| 1a04A | 2 | 0.981 | 100 | 0.118 | Contact Map | 0.704 |
| 3kloA | 4 | 0.9857 | 100 | 0.14 | Contact Map | 0.454 |
| 1yioA | 1 | 0.9667 | 100 | 0.154 | Contact Map | 0.706 |
| 1ys7A | 2 | 0.981 | 100 | 0.173 | Contact Map | 0.764 |
| 3q9sA | 1 | 0.9524 | 100 | 0.183 | Contact Map | 0.667 |
| 4b09A | 12 | 0.981 | 100 | 0.191 | Contact Map | 0.665 |
| 2gwrA | 1 | 0.9762 | 100 | 0.214 | Contact Map | 0.691 |
Sequence Conservation (Image Generated using WebLogo v3)