| UniProt: | P52076 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13026 | ||
| Length: | 219 (217) | ||
| Sequences: | 28941 | ||
| Seq/Len: | 133.37 |
| QSEB
Paralog alert: 0.93 [within 20: 0.57] - ratio of genomes with paralogs Cluster includes: ARCA BAER BASR BGLJ CPXR CREB CSGD CUSR DCUR DPIA EVGA FIMZ KDPE NARL NARP OMPR PHOB PHOP QSEB RCSB RSTA TORR UHPA UVRY YEDW YGEK YHJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 13_G | 29_W | 3.509 | 1.00 | |
| 13_G | 31_T | 2.795 | 1.00 | |
| 34_R | 56_G | 2.626 | 1.00 | |
| 17_K | 29_W | 2.555 | 1.00 | |
| 6_I | 36_G | 2.47 | 1.00 | |
| 32_Q | 56_G | 2.464 | 1.00 | |
| 188_N | 191_E | 2.409 | 1.00 | |
| 57_M | 65_E | 2.35 | 1.00 | |
| 153_K | 156_A | 2.304 | 1.00 | |
| 171_R | 191_E | 2.29 | 1.00 | |
| 28_D | 45_Y | 2.275 | 1.00 | |
| 17_K | 21_S | 2.214 | 1.00 | |
| 33_G | 57_M | 2.158 | 1.00 | |
| 84_L | 104_A | 2.137 | 1.00 | |
| 154_E | 200_K | 2.12 | 1.00 | |
| 32_Q | 35_Q | 2.08 | 1.00 | |
| 87_R | 107_E | 2.049 | 1.00 | |
| 2_R | 26_S | 2.001 | 1.00 | |
| 19_G | 105_L | 1.996 | 1.00 | |
| 41_Y | 69_K | 1.979 | 1.00 | |
| 37_K | 65_E | 1.955 | 1.00 | |
| 58_D | 61_D | 1.902 | 1.00 | |
| 31_T | 35_Q | 1.876 | 1.00 | |
| 207_R | 217_G | 1.85 | 1.00 | |
| 131_N | 144_A | 1.848 | 1.00 | |
| 30_F | 39_A | 1.774 | 1.00 | |
| 47_A | 112_L | 1.765 | 1.00 | |
| 207_R | 215_T | 1.753 | 1.00 | |
| 2_R | 28_D | 1.741 | 1.00 | |
| 159_E | 163_R | 1.736 | 1.00 | |
| 193_H | 196_H | 1.728 | 1.00 | |
| 77_I | 90_G | 1.728 | 1.00 | |
| 128_R | 133_M | 1.72 | 1.00 | |
| 20_L | 112_L | 1.706 | 1.00 | |
| 63_L | 75_V | 1.697 | 1.00 | |
| 50_L | 62_I | 1.674 | 1.00 | |
| 76_L | 115_L | 1.647 | 1.00 | |
| 50_L | 63_L | 1.625 | 1.00 | |
| 52_L | 77_I | 1.619 | 1.00 | |
| 140_I | 147_P | 1.619 | 1.00 | |
| 53_T | 81_R | 1.587 | 1.00 | |
| 164_N | 167_R | 1.579 | 1.00 | |
| 134_L | 162_M | 1.568 | 1.00 | |
| 160_L | 174_I | 1.566 | 1.00 | |
| 96_D | 118_R | 1.549 | 1.00 | |
| 4_L | 30_F | 1.542 | 1.00 | |
| 92_R | 113_E | 1.538 | 1.00 | |
| 133_M | 142_T | 1.523 | 1.00 | |
| 160_L | 177_K | 1.495 | 1.00 | |
| 65_E | 68_E | 1.49 | 1.00 | |
| 81_R | 86_E | 1.476 | 1.00 | |
| 63_L | 77_I | 1.471 | 1.00 | |
| 77_I | 95_A | 1.463 | 1.00 | |
| 7_E | 13_G | 1.459 | 1.00 | |
| 6_I | 54_L | 1.451 | 1.00 | |
| 33_G | 62_I | 1.439 | 1.00 | |
| 48_V | 73_E | 1.417 | 1.00 | |
| 169_L | 177_K | 1.394 | 0.99 | |
| 97_D | 111_R | 1.387 | 0.99 | |
| 57_M | 61_D | 1.381 | 0.99 | |
| 170_S | 173_L | 1.373 | 0.99 | |
| 37_K | 62_I | 1.371 | 0.99 | |
| 67_R | 96_D | 1.36 | 0.99 | |
| 28_D | 39_A | 1.353 | 0.99 | |
| 23_M | 109_A | 1.342 | 0.99 | |
| 194_V | 198_R | 1.339 | 0.99 | |
| 60_R | 93_L | 1.329 | 0.99 | |
| 61_D | 64_R | 1.28 | 0.99 | |
| 52_L | 60_R | 1.263 | 0.99 | |
| 165_A | 169_L | 1.262 | 0.99 | |
| 39_A | 43_A | 1.26 | 0.99 | |
| 65_E | 69_K | 1.25 | 0.99 | |
| 135_D | 138_K | 1.244 | 0.98 | |
| 34_R | 57_M | 1.232 | 0.98 | |
| 38_E | 42_S | 1.232 | 0.98 | |
| 24_G | 113_E | 1.219 | 0.98 | |
| 209_V | 215_T | 1.217 | 0.98 | |
| 39_A | 42_S | 1.213 | 0.98 | |
| 34_R | 38_E | 1.212 | 0.98 | |
| 25_F | 113_E | 1.19 | 0.98 | |
| 160_L | 169_L | 1.183 | 0.98 | |
| 37_K | 57_M | 1.182 | 0.98 | |
| 40_L | 66_W | 1.171 | 0.98 | |
| 47_A | 116_M | 1.16 | 0.97 | |
| 28_D | 43_A | 1.158 | 0.97 | |
| 3_I | 25_F | 1.152 | 0.97 | |
| 139_R | 212_I | 1.151 | 0.97 | |
| 139_R | 156_A | 1.139 | 0.97 | |
| 30_F | 36_G | 1.139 | 0.97 | |
| 83_A | 86_E | 1.135 | 0.97 | |
| 10_M | 31_T | 1.124 | 0.97 | |
| 8_D | 51_D | 1.123 | 0.97 | |
| 189_A | 193_H | 1.122 | 0.97 | |
| 64_R | 89_E | 1.115 | 0.96 | |
| 35_Q | 38_E | 1.105 | 0.96 | |
| 53_T | 80_A | 1.093 | 0.96 | |
| 192_V | 195_H | 1.089 | 0.96 | |
| 54_L | 62_I | 1.065 | 0.95 | |
| 136_P | 159_E | 1.062 | 0.95 | |
| 153_K | 179_Y | 1.057 | 0.95 | |
| 167_R | 173_L | 1.057 | 0.95 | |
| 172_K | 187_S | 1.055 | 0.95 | |
| 85_A | 89_E | 1.053 | 0.95 | |
| 115_L | 118_R | 1.048 | 0.94 | |
| 16_I | 78_L | 1.046 | 0.94 | |
| 4_L | 36_G | 1.045 | 0.94 | |
| 172_K | 176_E | 1.042 | 0.94 | |
| 126_E | 133_M | 1.034 | 0.94 | |
| 4_L | 45_Y | 1.033 | 0.94 | |
| 60_R | 89_E | 1.032 | 0.94 | |
| 160_L | 164_N | 1.03 | 0.94 | |
| 36_G | 40_L | 1.029 | 0.94 | |
| 6_I | 48_V | 1.028 | 0.94 | |
| 5_L | 27_V | 1.027 | 0.94 | |
| 35_Q | 39_A | 1.026 | 0.94 | |
| 142_T | 147_P | 1.02 | 0.93 | |
| 137_G | 167_R | 1.015 | 0.93 | |
| 151_K | 200_K | 1.013 | 0.93 | |
| 84_L | 88_V | 1.012 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3r0jA | 2 | 1 | 100 | 0.084 | Contact Map | 0.693 |
| 2gwrA | 1 | 0.9954 | 100 | 0.085 | Contact Map | 0.682 |
| 1ys7A | 2 | 1 | 100 | 0.093 | Contact Map | 0.784 |
| 2oqrA | 1 | 0.9909 | 100 | 0.111 | Contact Map | 0.575 |
| 1kgsA | 1 | 1 | 100 | 0.117 | Contact Map | 0.719 |
| 4b09A | 12 | 0.9954 | 100 | 0.127 | Contact Map | 0.675 |
| 2hqrA | 2 | 0.968 | 100 | 0.131 | Contact Map | 0.687 |
| 1p2fA | 1 | 0.9635 | 100 | 0.149 | Contact Map | 0.752 |
| 3q9sA | 1 | 0.9498 | 100 | 0.165 | Contact Map | 0.696 |
| 3c3wA | 2 | 0.9452 | 100 | 0.248 | Contact Map | 0.643 |
Sequence Conservation (Image Generated using WebLogo v3)