| UniProt: | P0AE88 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10020 | ||
| Length: | 232 (225) | ||
| Sequences: | 27290 | ||
| Seq/Len: | 121.29 |
| CPXR
Paralog alert: 0.94 [within 20: 0.55] - ratio of genomes with paralogs Cluster includes: ARCA BAER BASR BGLJ CPXR CREB CSGD CUSR DCUR DPIA EVGA FIMZ KDPE NARL NARP OMPR PHOB PHOP QSEB RCSB RSTA TORR UHPA UVRY YEDW YGEK YHJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 14_T | 30_V | 3.543 | 1.00 | |
| 14_T | 32_H | 2.838 | 1.00 | |
| 35_E | 56_K | 2.601 | 1.00 | |
| 18_K | 30_V | 2.598 | 1.00 | |
| 7_V | 37_A | 2.466 | 1.00 | |
| 33_D | 56_K | 2.462 | 1.00 | |
| 160_T | 163_T | 2.415 | 1.00 | |
| 57_K | 65_A | 2.344 | 1.00 | |
| 195_R | 198_D | 2.34 | 1.00 | |
| 161_E | 207_K | 2.322 | 1.00 | |
| 29_I | 45_I | 2.315 | 1.00 | |
| 83_E | 103_N | 2.311 | 1.00 | |
| 178_R | 198_D | 2.307 | 1.00 | |
| 18_K | 22_E | 2.283 | 1.00 | |
| 34_G | 57_K | 2.155 | 1.00 | |
| 86_R | 106_E | 2.152 | 1.00 | |
| 33_D | 36_Q | 2.084 | 1.00 | |
| 138_A | 151_D | 2.005 | 1.00 | |
| 20_L | 104_D | 1.999 | 1.00 | |
| 3_K | 27_N | 1.974 | 1.00 | |
| 38_L | 65_A | 1.955 | 1.00 | |
| 135_E | 140_V | 1.905 | 1.00 | |
| 58_N | 61_D | 1.884 | 1.00 | |
| 166_Y | 170_Q | 1.857 | 1.00 | |
| 147_E | 154_T | 1.854 | 1.00 | |
| 219_K | 229_V | 1.818 | 1.00 | |
| 32_H | 36_Q | 1.811 | 1.00 | |
| 200_H | 203_N | 1.803 | 1.00 | |
| 47_L | 111_I | 1.792 | 1.00 | |
| 3_K | 29_I | 1.772 | 1.00 | |
| 31_A | 40_L | 1.763 | 1.00 | |
| 76_M | 89_G | 1.757 | 1.00 | |
| 21_L | 111_I | 1.73 | 1.00 | |
| 141_L | 169_A | 1.727 | 1.00 | |
| 75_I | 114_I | 1.71 | 1.00 | |
| 63_L | 74_V | 1.689 | 1.00 | |
| 219_K | 227_L | 1.684 | 1.00 | |
| 52_V | 76_M | 1.669 | 1.00 | |
| 95_D | 117_R | 1.662 | 1.00 | |
| 91_E | 112_R | 1.657 | 1.00 | |
| 140_V | 149_S | 1.618 | 1.00 | |
| 53_M | 80_R | 1.618 | 1.00 | |
| 171_H | 174_Q | 1.61 | 1.00 | |
| 167_L | 181_L | 1.608 | 1.00 | |
| 50_L | 62_T | 1.604 | 1.00 | |
| 50_L | 63_L | 1.6 | 1.00 | |
| 24_E | 108_V | 1.569 | 1.00 | |
| 5_L | 31_A | 1.548 | 1.00 | |
| 63_L | 76_M | 1.523 | 1.00 | |
| 65_A | 68_Q | 1.509 | 1.00 | |
| 48_L | 72_T | 1.495 | 1.00 | |
| 80_R | 85_D | 1.491 | 1.00 | |
| 167_L | 184_E | 1.483 | 1.00 | |
| 177_S | 180_H | 1.476 | 1.00 | |
| 7_V | 54_M | 1.451 | 1.00 | |
| 76_M | 94_A | 1.446 | 1.00 | |
| 34_G | 62_T | 1.421 | 1.00 | |
| 57_K | 61_D | 1.407 | 0.99 | |
| 8_D | 14_T | 1.393 | 0.99 | |
| 60_I | 92_L | 1.38 | 0.99 | |
| 29_I | 40_L | 1.376 | 0.99 | |
| 67_R | 95_D | 1.37 | 0.99 | |
| 38_L | 62_T | 1.366 | 0.99 | |
| 142_N | 145_R | 1.325 | 0.99 | |
| 61_D | 64_K | 1.323 | 0.99 | |
| 96_D | 110_R | 1.295 | 0.99 | |
| 172_L | 176_V | 1.287 | 0.99 | |
| 35_E | 57_K | 1.281 | 0.99 | |
| 146_Q | 163_T | 1.278 | 0.99 | |
| 52_V | 60_I | 1.27 | 0.99 | |
| 42_D | 69_T | 1.248 | 0.99 | |
| 40_L | 43_D | 1.241 | 0.98 | |
| 167_L | 176_V | 1.237 | 0.98 | |
| 26_F | 112_R | 1.227 | 0.98 | |
| 201_I | 205_R | 1.218 | 0.98 | |
| 221_L | 227_L | 1.214 | 0.98 | |
| 143_P | 166_Y | 1.211 | 0.98 | |
| 47_L | 115_L | 1.204 | 0.98 | |
| 35_E | 39_D | 1.2 | 0.98 | |
| 25_G | 112_R | 1.194 | 0.98 | |
| 114_I | 117_R | 1.19 | 0.98 | |
| 149_S | 154_T | 1.18 | 0.98 | |
| 141_L | 162_F | 1.163 | 0.97 | |
| 196_A | 200_H | 1.163 | 0.97 | |
| 38_L | 57_K | 1.163 | 0.97 | |
| 82_S | 85_D | 1.151 | 0.97 | |
| 174_Q | 180_H | 1.146 | 0.97 | |
| 36_Q | 39_D | 1.134 | 0.97 | |
| 31_A | 37_A | 1.133 | 0.97 | |
| 41_L | 66_L | 1.133 | 0.97 | |
| 176_V | 184_E | 1.124 | 0.97 | |
| 11_R | 32_H | 1.124 | 0.97 | |
| 64_K | 88_L | 1.123 | 0.97 | |
| 29_I | 43_D | 1.111 | 0.96 | |
| 158_T | 207_K | 1.102 | 0.96 | |
| 160_T | 186_L | 1.098 | 0.96 | |
| 133_T | 140_V | 1.097 | 0.96 | |
| 144_G | 174_Q | 1.094 | 0.96 | |
| 4_I | 26_F | 1.094 | 0.96 | |
| 24_E | 112_R | 1.09 | 0.96 | |
| 199_M | 202_S | 1.088 | 0.96 | |
| 9_D | 51_D | 1.087 | 0.96 | |
| 84_L | 88_L | 1.086 | 0.96 | |
| 146_Q | 224_R | 1.085 | 0.96 | |
| 179_E | 194_D | 1.074 | 0.95 | |
| 5_L | 45_I | 1.072 | 0.95 | |
| 7_V | 48_L | 1.069 | 0.95 | |
| 36_Q | 40_L | 1.064 | 0.95 | |
| 87_V | 105_R | 1.061 | 0.95 | |
| 113_A | 118_S | 1.061 | 0.95 | |
| 17_L | 77_L | 1.061 | 0.95 | |
| 5_L | 37_A | 1.054 | 0.95 | |
| 60_I | 88_L | 1.053 | 0.95 | |
| 136_V | 228_M | 1.044 | 0.94 | |
| 53_M | 79_A | 1.034 | 0.94 | |
| 6_L | 28_V | 1.034 | 0.94 | |
| 83_E | 87_V | 1.02 | 0.93 | |
| 54_M | 62_T | 1.006 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1ys7A | 2 | 0.9698 | 100 | 0.059 | Contact Map | 0.778 |
| 2gwrA | 1 | 0.9655 | 100 | 0.068 | Contact Map | 0.687 |
| 3r0jA | 2 | 0.9741 | 100 | 0.071 | Contact Map | 0.684 |
| 2oqrA | 1 | 0.9741 | 100 | 0.072 | Contact Map | 0.572 |
| 4b09A | 12 | 0.9741 | 100 | 0.095 | Contact Map | 0.679 |
| 1kgsA | 1 | 0.9569 | 100 | 0.108 | Contact Map | 0.723 |
| 1p2fA | 1 | 0.9353 | 100 | 0.121 | Contact Map | 0.744 |
| 2hqrA | 2 | 0.9267 | 100 | 0.125 | Contact Map | 0.684 |
| 3q9sA | 1 | 0.9138 | 100 | 0.134 | Contact Map | 0.688 |
| 3c3wA | 2 | 0.9052 | 100 | 0.217 | Contact Map | 0.64 |
Sequence Conservation (Image Generated using WebLogo v3)