| UniProt: | P21866 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10517 | ||
| Length: | 225 (223) | ||
| Sequences: | 29101 | ||
| Seq/Len: | 130.50 |
| KDPE
Paralog alert: 0.94 [within 20: 0.58] - ratio of genomes with paralogs Cluster includes: ARCA BAER BASR BGLJ CPXR CREB CSGD CUSR DCUR DPIA EVGA FIMZ KDPE NARL NARP OMPR PHOB PHOP QSEB RCSB RSTA TORR UHPA UVRY YEDW YGEK YHJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 14_R | 30_E | 3.533 | 1.00 | |
| 14_R | 32_E | 2.823 | 1.00 | |
| 35_Q | 57_D | 2.63 | 1.00 | |
| 18_R | 30_E | 2.574 | 1.00 | |
| 33_T | 57_D | 2.537 | 1.00 | |
| 7_V | 37_G | 2.512 | 1.00 | |
| 58_G | 66_D | 2.348 | 1.00 | |
| 29_F | 46_P | 2.323 | 1.00 | |
| 190_H | 193_R | 2.318 | 1.00 | |
| 155_I | 158_R | 2.274 | 1.00 | |
| 173_Q | 193_R | 2.264 | 1.00 | |
| 18_R | 22_E | 2.259 | 1.00 | |
| 84_E | 104_G | 2.19 | 1.00 | |
| 34_L | 58_G | 2.187 | 1.00 | |
| 33_T | 36_R | 2.179 | 1.00 | |
| 156_E | 202_K | 2.081 | 1.00 | |
| 87_K | 107_E | 2.048 | 1.00 | |
| 59_D | 62_E | 2.021 | 1.00 | |
| 3_N | 27_R | 1.996 | 1.00 | |
| 42_A | 70_W | 1.987 | 1.00 | |
| 20_A | 105_I | 1.984 | 1.00 | |
| 38_L | 66_D | 1.971 | 1.00 | |
| 32_E | 36_R | 1.881 | 1.00 | |
| 31_A | 40_E | 1.836 | 1.00 | |
| 133_D | 146_G | 1.826 | 1.00 | |
| 3_N | 29_F | 1.807 | 1.00 | |
| 130_K | 135_T | 1.795 | 1.00 | |
| 48_L | 112_L | 1.79 | 1.00 | |
| 214_I | 224_M | 1.783 | 1.00 | |
| 161_A | 165_N | 1.776 | 1.00 | |
| 64_I | 75_V | 1.766 | 1.00 | |
| 214_I | 222_R | 1.762 | 1.00 | |
| 77_V | 90_A | 1.743 | 1.00 | |
| 195_Y | 198_H | 1.72 | 1.00 | |
| 21_L | 112_L | 1.717 | 1.00 | |
| 51_L | 63_F | 1.711 | 1.00 | |
| 76_I | 115_A | 1.709 | 1.00 | |
| 53_L | 77_V | 1.702 | 1.00 | |
| 142_V | 149_E | 1.697 | 1.00 | |
| 51_L | 64_I | 1.664 | 1.00 | |
| 136_V | 164_L | 1.648 | 1.00 | |
| 162_V | 176_L | 1.629 | 1.00 | |
| 92_D | 113_R | 1.62 | 1.00 | |
| 54_G | 81_R | 1.605 | 1.00 | |
| 166_N | 169_K | 1.572 | 1.00 | |
| 5_L | 31_A | 1.567 | 1.00 | |
| 96_D | 118_R | 1.547 | 1.00 | |
| 66_D | 69_Q | 1.54 | 1.00 | |
| 135_T | 144_H | 1.515 | 1.00 | |
| 64_I | 77_V | 1.496 | 1.00 | |
| 162_V | 179_Q | 1.491 | 1.00 | |
| 7_V | 55_L | 1.482 | 1.00 | |
| 81_R | 86_D | 1.48 | 1.00 | |
| 77_V | 95_A | 1.461 | 1.00 | |
| 49_I | 73_V | 1.44 | 1.00 | |
| 38_L | 63_F | 1.432 | 1.00 | |
| 34_L | 63_F | 1.428 | 1.00 | |
| 8_E | 14_R | 1.426 | 1.00 | |
| 97_D | 111_R | 1.423 | 1.00 | |
| 172_T | 175_Q | 1.399 | 0.99 | |
| 58_G | 62_E | 1.37 | 0.99 | |
| 29_F | 40_E | 1.338 | 0.99 | |
| 61_I | 93_A | 1.324 | 0.99 | |
| 171_L | 179_Q | 1.324 | 0.99 | |
| 68_R | 96_D | 1.322 | 0.99 | |
| 196_M | 200_R | 1.317 | 0.99 | |
| 53_L | 61_I | 1.311 | 0.99 | |
| 137_D | 140_A | 1.305 | 0.99 | |
| 62_E | 65_R | 1.289 | 0.99 | |
| 167_A | 171_L | 1.281 | 0.99 | |
| 25_G | 113_R | 1.274 | 0.99 | |
| 40_E | 44_R | 1.26 | 0.99 | |
| 24_D | 109_Q | 1.257 | 0.99 | |
| 66_D | 70_W | 1.246 | 0.98 | |
| 35_Q | 58_G | 1.246 | 0.98 | |
| 39_L | 43_T | 1.245 | 0.98 | |
| 40_E | 43_T | 1.235 | 0.98 | |
| 35_Q | 39_L | 1.232 | 0.98 | |
| 41_A | 67_L | 1.205 | 0.98 | |
| 26_M | 113_R | 1.202 | 0.98 | |
| 38_L | 58_G | 1.197 | 0.98 | |
| 48_L | 116_L | 1.195 | 0.98 | |
| 216_E | 222_R | 1.177 | 0.98 | |
| 162_V | 171_L | 1.169 | 0.97 | |
| 141_R | 158_R | 1.167 | 0.97 | |
| 31_A | 37_G | 1.165 | 0.97 | |
| 65_R | 89_A | 1.147 | 0.97 | |
| 4_V | 26_M | 1.144 | 0.97 | |
| 9_D | 52_D | 1.143 | 0.97 | |
| 83_E | 86_D | 1.141 | 0.97 | |
| 191_Y | 195_Y | 1.119 | 0.96 | |
| 11_Q | 32_E | 1.116 | 0.96 | |
| 141_R | 219_I | 1.114 | 0.96 | |
| 54_G | 80_A | 1.113 | 0.96 | |
| 36_R | 39_L | 1.106 | 0.96 | |
| 37_G | 41_A | 1.103 | 0.96 | |
| 169_K | 175_Q | 1.091 | 0.96 | |
| 194_I | 197_G | 1.084 | 0.96 | |
| 17_L | 78_L | 1.074 | 0.95 | |
| 7_V | 49_I | 1.065 | 0.95 | |
| 5_L | 37_G | 1.063 | 0.95 | |
| 55_L | 63_F | 1.057 | 0.95 | |
| 6_I | 28_V | 1.054 | 0.95 | |
| 5_L | 46_P | 1.049 | 0.94 | |
| 115_A | 118_R | 1.047 | 0.94 | |
| 8_E | 55_L | 1.045 | 0.94 | |
| 155_I | 181_W | 1.044 | 0.94 | |
| 61_I | 89_A | 1.041 | 0.94 | |
| 138_L | 161_A | 1.04 | 0.94 | |
| 29_F | 44_R | 1.036 | 0.94 | |
| 17_L | 108_L | 1.035 | 0.94 | |
| 153_T | 202_K | 1.033 | 0.94 | |
| 174_R | 189_S | 1.033 | 0.94 | |
| 174_R | 178_N | 1.031 | 0.94 | |
| 85_S | 89_A | 1.029 | 0.94 | |
| 144_H | 149_E | 1.026 | 0.94 | |
| 36_R | 40_E | 1.02 | 0.93 | |
| 162_V | 166_N | 1.017 | 0.93 | |
| 84_E | 88_I | 1.017 | 0.93 | |
| 87_K | 100_S | 1.003 | 0.93 | |
| 40_E | 46_P | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2gwrA | 1 | 0.9911 | 100 | 0.102 | Contact Map | 0.678 |
| 1ys7A | 2 | 0.9911 | 100 | 0.103 | Contact Map | 0.787 |
| 3r0jA | 2 | 0.9911 | 100 | 0.106 | Contact Map | 0.686 |
| 2oqrA | 1 | 0.9956 | 100 | 0.117 | Contact Map | 0.569 |
| 4b09A | 12 | 0.9956 | 100 | 0.137 | Contact Map | 0.678 |
| 1kgsA | 1 | 0.9867 | 100 | 0.139 | Contact Map | 0.724 |
| 2hqrA | 2 | 0.9511 | 100 | 0.154 | Contact Map | 0.686 |
| 1p2fA | 1 | 0.9556 | 100 | 0.154 | Contact Map | 0.754 |
| 3q9sA | 1 | 0.9467 | 100 | 0.172 | Contact Map | 0.681 |
| 3c3wA | 2 | 0.9333 | 100 | 0.266 | Contact Map | 0.629 |
Sequence Conservation (Image Generated using WebLogo v3)