| UniProt: | P69228 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11618 | ||
| Length: | 240 (222) | ||
| Sequences: | 28233 | ||
| Seq/Len: | 127.18 |
| BAER
Paralog alert: 0.94 [within 20: 0.56] - ratio of genomes with paralogs Cluster includes: ARCA BAER BASR BGLJ CPXR CREB CSGD CUSR DCUR DPIA EVGA FIMZ KDPE NARL NARP OMPR PHOB PHOP QSEB RCSB RSTA TORR UHPA UVRY YEDW YGEK YHJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 23_G | 39_L | 3.522 | 1.00 | |
| 23_G | 41_S | 2.865 | 1.00 | |
| 44_D | 66_G | 2.657 | 1.00 | |
| 27_I | 39_L | 2.538 | 1.00 | |
| 42_H | 66_G | 2.494 | 1.00 | |
| 16_V | 46_V | 2.463 | 1.00 | |
| 67_T | 75_E | 2.403 | 1.00 | |
| 38_T | 55_P | 2.345 | 1.00 | |
| 164_A | 167_R | 2.284 | 1.00 | |
| 93_E | 113_S | 2.241 | 1.00 | |
| 27_I | 31_R | 2.228 | 1.00 | |
| 199_R | 202_D | 2.222 | 1.00 | |
| 182_R | 202_D | 2.217 | 1.00 | |
| 43_G | 67_T | 2.142 | 1.00 | |
| 42_H | 45_Q | 2.126 | 1.00 | |
| 165_E | 211_K | 2.075 | 1.00 | |
| 51_R | 79_F | 2.063 | 1.00 | |
| 96_R | 116_E | 2.049 | 1.00 | |
| 29_Y | 114_P | 2.021 | 1.00 | |
| 12_R | 36_A | 2.007 | 1.00 | |
| 47_L | 75_E | 1.999 | 1.00 | |
| 68_D | 71_T | 1.945 | 1.00 | |
| 142_P | 155_R | 1.937 | 1.00 | |
| 41_S | 45_Q | 1.882 | 1.00 | |
| 12_R | 38_T | 1.852 | 1.00 | |
| 170_K | 174_H | 1.838 | 1.00 | |
| 57_L | 121_V | 1.802 | 1.00 | |
| 40_I | 49_Y | 1.787 | 1.00 | |
| 223_R | 233_E | 1.779 | 1.00 | |
| 151_Q | 158_M | 1.767 | 1.00 | |
| 86_M | 99_G | 1.755 | 1.00 | |
| 30_L | 121_V | 1.728 | 1.00 | |
| 73_C | 84_I | 1.727 | 1.00 | |
| 204_H | 207_N | 1.708 | 1.00 | |
| 139_A | 144_I | 1.691 | 1.00 | |
| 85_V | 124_I | 1.685 | 1.00 | |
| 62_L | 86_M | 1.679 | 1.00 | |
| 60_L | 72_L | 1.646 | 1.00 | |
| 144_I | 153_S | 1.629 | 1.00 | |
| 60_L | 73_C | 1.627 | 1.00 | |
| 145_I | 173_S | 1.624 | 1.00 | |
| 223_R | 231_R | 1.623 | 1.00 | |
| 101_E | 122_K | 1.616 | 1.00 | |
| 63_M | 90_K | 1.61 | 1.00 | |
| 175_E | 178_K | 1.604 | 1.00 | |
| 105_D | 127_R | 1.593 | 1.00 | |
| 171_T | 185_L | 1.589 | 1.00 | |
| 33_A | 118_V | 1.587 | 1.00 | |
| 75_E | 78_R | 1.548 | 1.00 | |
| 14_L | 40_I | 1.539 | 1.00 | |
| 171_T | 188_H | 1.521 | 1.00 | |
| 73_C | 86_M | 1.497 | 1.00 | |
| 181_S | 184_Q | 1.465 | 1.00 | |
| 90_K | 95_D | 1.457 | 1.00 | |
| 16_V | 64_L | 1.453 | 1.00 | |
| 86_M | 104_A | 1.451 | 1.00 | |
| 58_I | 82_I | 1.442 | 1.00 | |
| 38_T | 49_Y | 1.41 | 1.00 | |
| 17_E | 23_G | 1.406 | 0.99 | |
| 67_T | 71_T | 1.403 | 0.99 | |
| 43_G | 72_L | 1.398 | 0.99 | |
| 106_D | 120_R | 1.394 | 0.99 | |
| 47_L | 72_L | 1.384 | 0.99 | |
| 77_R | 105_D | 1.373 | 0.99 | |
| 70_L | 102_I | 1.357 | 0.99 | |
| 146_D | 149_R | 1.314 | 0.99 | |
| 180_F | 188_H | 1.312 | 0.99 | |
| 71_T | 74_R | 1.306 | 0.99 | |
| 44_D | 67_T | 1.294 | 0.99 | |
| 75_E | 79_F | 1.287 | 0.99 | |
| 62_L | 70_L | 1.28 | 0.99 | |
| 49_Y | 53_T | 1.276 | 0.99 | |
| 48_P | 52_Q | 1.27 | 0.99 | |
| 49_Y | 52_Q | 1.262 | 0.99 | |
| 176_P | 180_F | 1.251 | 0.99 | |
| 47_L | 67_T | 1.204 | 0.98 | |
| 50_V | 76_I | 1.202 | 0.98 | |
| 44_D | 48_P | 1.2 | 0.98 | |
| 205_I | 209_R | 1.199 | 0.98 | |
| 33_A | 122_K | 1.199 | 0.98 | |
| 35_Y | 122_K | 1.198 | 0.98 | |
| 171_T | 180_F | 1.193 | 0.98 | |
| 225_V | 231_R | 1.185 | 0.98 | |
| 150_F | 167_R | 1.184 | 0.98 | |
| 57_L | 125_L | 1.183 | 0.98 | |
| 20_P | 41_S | 1.178 | 0.98 | |
| 153_S | 158_M | 1.155 | 0.97 | |
| 74_R | 98_L | 1.148 | 0.97 | |
| 40_I | 46_V | 1.144 | 0.97 | |
| 34_S | 122_K | 1.134 | 0.97 | |
| 45_Q | 48_P | 1.133 | 0.97 | |
| 92_E | 95_D | 1.12 | 0.96 | |
| 200_T | 204_H | 1.116 | 0.96 | |
| 18_D | 61_D | 1.112 | 0.96 | |
| 124_I | 127_R | 1.108 | 0.96 | |
| 38_T | 53_T | 1.104 | 0.96 | |
| 178_K | 184_Q | 1.1 | 0.96 | |
| 26_L | 87_V | 1.1 | 0.96 | |
| 147_E | 170_K | 1.099 | 0.96 | |
| 203_S | 206_K | 1.095 | 0.96 | |
| 46_V | 50_V | 1.09 | 0.96 | |
| 13_I | 35_Y | 1.09 | 0.96 | |
| 214_S | 224_A | 1.088 | 0.96 | |
| 94_I | 98_L | 1.06 | 0.95 | |
| 15_I | 37_P | 1.055 | 0.95 | |
| 63_M | 89_A | 1.054 | 0.95 | |
| 45_Q | 49_Y | 1.048 | 0.94 | |
| 16_V | 58_I | 1.047 | 0.94 | |
| 183_E | 198_D | 1.045 | 0.94 | |
| 97_L | 115_R | 1.044 | 0.94 | |
| 183_E | 187_N | 1.043 | 0.94 | |
| 14_L | 46_V | 1.041 | 0.94 | |
| 70_L | 98_L | 1.039 | 0.94 | |
| 14_L | 55_P | 1.039 | 0.94 | |
| 58_I | 76_I | 1.026 | 0.94 | |
| 171_T | 175_E | 1.022 | 0.93 | |
| 49_Y | 55_P | 1.019 | 0.93 | |
| 140_E | 232_W | 1.016 | 0.93 | |
| 64_L | 72_L | 1.015 | 0.93 | |
| 150_F | 228_V | 1.015 | 0.93 | |
| 145_I | 166_F | 1.014 | 0.93 | |
| 148_G | 178_K | 1.014 | 0.93 | |
| 167_R | 170_K | 1.005 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4b09A | 12 | 1 | 100 | 0.155 | Contact Map | 0.676 |
| 2gwrA | 1 | 0.9708 | 100 | 0.179 | Contact Map | 0.676 |
| 1ys7A | 2 | 0.9625 | 100 | 0.181 | Contact Map | 0.765 |
| 3r0jA | 2 | 0.975 | 100 | 0.185 | Contact Map | 0.694 |
| 2oqrA | 1 | 0.95 | 100 | 0.196 | Contact Map | 0.563 |
| 1kgsA | 1 | 0.9333 | 100 | 0.206 | Contact Map | 0.721 |
| 1p2fA | 1 | 0.9125 | 100 | 0.228 | Contact Map | 0.756 |
| 2hqrA | 2 | 0.9167 | 100 | 0.236 | Contact Map | 0.696 |
| 3q9sA | 1 | 0.925 | 100 | 0.245 | Contact Map | 0.669 |
| 3c3wA | 2 | 0.9 | 100 | 0.323 | Contact Map | 0.612 |
Sequence Conservation (Image Generated using WebLogo v3)