| UniProt: | P0AEF4 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13544 | ||
| Length: | 226 (201) | ||
| Sequences: | 17634 | ||
| Seq/Len: | 87.73 |
| DPIA
Paralog alert: 0.87 [within 20: 0.36] - ratio of genomes with paralogs Cluster includes: ARCA BAER BASR BGLJ CPXR CREB CSGD CUSR DCUR DPIA EVGA FIMZ KDPE NARL NARP OMPR PHOB PHOP QSEB RCSB RSTA TORR UHPA UVRY YEDW YGEK YHJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 17_A | 35_L | 3.41 | 1.00 | |
| 21_A | 35_L | 2.775 | 1.00 | |
| 10_V | 42_A | 2.7 | 1.00 | |
| 38_N | 62_D | 2.691 | 1.00 | |
| 40_A | 62_D | 2.658 | 1.00 | |
| 17_A | 37_G | 2.499 | 1.00 | |
| 39_L | 63_G | 2.403 | 1.00 | |
| 38_N | 41_Q | 2.34 | 1.00 | |
| 63_G | 71_E | 2.273 | 1.00 | |
| 178_H | 186_A | 2.22 | 1.00 | |
| 47_E | 75_A | 2.172 | 1.00 | |
| 37_G | 41_Q | 2.17 | 1.00 | |
| 64_R | 67_N | 2.08 | 1.00 | |
| 43_R | 71_E | 2.058 | 1.00 | |
| 6_T | 31_S | 2.056 | 1.00 | |
| 82_V | 121_F | 2.053 | 1.00 | |
| 83_F | 96_A | 2.023 | 1.00 | |
| 21_A | 25_R | 2.017 | 1.00 | |
| 56_L | 68_L | 1.938 | 1.00 | |
| 36_A | 45_M | 1.864 | 1.00 | |
| 23_Y | 111_Y | 1.855 | 1.00 | |
| 24_I | 118_L | 1.821 | 1.00 | |
| 69_L | 81_V | 1.819 | 1.00 | |
| 73_V | 102_F | 1.809 | 1.00 | |
| 180_A | 195_R | 1.783 | 1.00 | |
| 192_T | 195_R | 1.777 | 1.00 | |
| 29_G | 119_T | 1.737 | 1.00 | |
| 56_L | 69_L | 1.728 | 1.00 | |
| 197_Y | 200_Y | 1.719 | 1.00 | |
| 179_T | 182_T | 1.691 | 1.00 | |
| 160_D | 163_T | 1.673 | 1.00 | |
| 53_L | 118_L | 1.665 | 1.00 | |
| 162_L | 165_N | 1.614 | 1.00 | |
| 59_Y | 87_A | 1.604 | 1.00 | |
| 8_L | 36_A | 1.577 | 1.00 | |
| 87_A | 92_T | 1.549 | 1.00 | |
| 189_I | 194_A | 1.545 | 1.00 | |
| 45_M | 49_F | 1.528 | 1.00 | |
| 58_N | 83_F | 1.514 | 1.00 | |
| 71_E | 75_A | 1.496 | 1.00 | |
| 69_L | 83_F | 1.482 | 1.00 | |
| 45_M | 48_R | 1.474 | 1.00 | |
| 33_I | 51_P | 1.468 | 1.00 | |
| 63_G | 67_N | 1.458 | 1.00 | |
| 90_M | 110_A | 1.438 | 1.00 | |
| 27_I | 115_G | 1.434 | 1.00 | |
| 120_R | 125_K | 1.431 | 1.00 | |
| 93_V | 113_R | 1.414 | 1.00 | |
| 39_L | 68_L | 1.414 | 1.00 | |
| 71_E | 74_Q | 1.398 | 0.99 | |
| 67_N | 70_H | 1.397 | 0.99 | |
| 198_L | 202_A | 1.38 | 0.99 | |
| 7_L | 30_F | 1.376 | 0.99 | |
| 34_L | 49_F | 1.355 | 0.99 | |
| 193_T | 197_Y | 1.354 | 0.99 | |
| 8_L | 45_M | 1.351 | 0.99 | |
| 103_D | 117_T | 1.349 | 0.99 | |
| 43_R | 68_L | 1.349 | 0.99 | |
| 10_V | 60_L | 1.341 | 0.99 | |
| 6_T | 33_I | 1.316 | 0.99 | |
| 191_R | 195_R | 1.294 | 0.99 | |
| 165_N | 169_K | 1.293 | 0.99 | |
| 54_I | 79_G | 1.287 | 0.99 | |
| 42_A | 46_I | 1.284 | 0.99 | |
| 40_A | 63_G | 1.272 | 0.99 | |
| 40_A | 44_M | 1.27 | 0.99 | |
| 173_E | 176_V | 1.255 | 0.99 | |
| 27_I | 119_T | 1.252 | 0.99 | |
| 192_T | 199_E | 1.25 | 0.99 | |
| 196_R | 199_E | 1.248 | 0.99 | |
| 12_D | 57_D | 1.245 | 0.98 | |
| 24_I | 30_F | 1.243 | 0.98 | |
| 30_F | 119_T | 1.242 | 0.98 | |
| 66_I | 99_C | 1.233 | 0.98 | |
| 113_R | 116_Q | 1.233 | 0.98 | |
| 76_H | 79_G | 1.229 | 0.98 | |
| 181_E | 185_Q | 1.228 | 0.98 | |
| 44_M | 48_R | 1.221 | 0.98 | |
| 8_L | 34_L | 1.22 | 0.98 | |
| 5_L | 122_R | 1.216 | 0.98 | |
| 195_R | 198_L | 1.213 | 0.98 | |
| 70_H | 95_E | 1.211 | 0.98 | |
| 46_I | 72_L | 1.211 | 0.98 | |
| 8_L | 42_A | 1.21 | 0.98 | |
| 181_E | 191_R | 1.194 | 0.98 | |
| 53_L | 122_R | 1.177 | 0.98 | |
| 90_M | 94_S | 1.17 | 0.97 | |
| 168_R | 172_K | 1.167 | 0.97 | |
| 82_V | 103_D | 1.161 | 0.97 | |
| 43_R | 63_G | 1.152 | 0.97 | |
| 41_Q | 44_M | 1.147 | 0.97 | |
| 192_T | 196_R | 1.143 | 0.97 | |
| 8_L | 46_I | 1.142 | 0.97 | |
| 89_D | 92_T | 1.142 | 0.97 | |
| 58_N | 66_I | 1.132 | 0.97 | |
| 11_E | 60_L | 1.131 | 0.97 | |
| 115_G | 119_T | 1.108 | 0.96 | |
| 196_R | 200_Y | 1.092 | 0.96 | |
| 102_F | 124_R | 1.088 | 0.96 | |
| 34_L | 51_P | 1.088 | 0.96 | |
| 116_Q | 120_R | 1.084 | 0.96 | |
| 59_Y | 86_A | 1.072 | 0.95 | |
| 167_V | 170_L | 1.066 | 0.95 | |
| 34_L | 45_M | 1.061 | 0.95 | |
| 11_E | 17_A | 1.06 | 0.95 | |
| 10_V | 36_A | 1.056 | 0.95 | |
| 8_L | 51_P | 1.045 | 0.94 | |
| 54_I | 72_L | 1.024 | 0.93 | |
| 41_Q | 45_M | 1.022 | 0.93 | |
| 98_R | 119_T | 1.018 | 0.93 | |
| 69_L | 101_V | 1.013 | 0.93 | |
| 36_A | 42_A | 1.01 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3c3wA | 2 | 0.9381 | 100 | 0.237 | Contact Map | 0.662 |
| 4gvpA | 4 | 0.8894 | 100 | 0.246 | Contact Map | 0.84 |
| 4hyeA | 2 | 0.8673 | 100 | 0.258 | Contact Map | 0.852 |
| 1a04A | 2 | 0.9115 | 100 | 0.261 | Contact Map | 0.686 |
| 1yioA | 1 | 0.8894 | 100 | 0.287 | Contact Map | 0.683 |
| 3kloA | 4 | 0.9425 | 100 | 0.287 | Contact Map | 0.46 |
| 1ys7A | 2 | 0.9558 | 100 | 0.314 | Contact Map | 0.778 |
| 2oqrA | 1 | 0.9425 | 100 | 0.323 | Contact Map | 0.549 |
| 3r0jA | 2 | 0.9602 | 100 | 0.324 | Contact Map | 0.671 |
| 4b09A | 12 | 0.969 | 100 | 0.325 | Contact Map | 0.671 |
Sequence Conservation (Image Generated using WebLogo v3)