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NARP - Nitrate/nitrite response regulator protein NarP
UniProt: P31802 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11527
Length: 215 (202)
Sequences: 29934
Seq/Len: 148.19

NARP
Paralog alert: 0.94 [within 20: 0.58] - ratio of genomes with paralogs
Cluster includes: ARCA BAER BASR BGLJ CPXR CREB CSGD CUSR DCUR DPIA EVGA FIMZ KDPE NARL NARP OMPR PHOB PHOP QSEB RCSB RSTA TORR UHPA UVRY YEDW YGEK YHJB
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
19_R 37_E 3.574 1.00
19_R 39_G 2.891 1.00
42_A 64_G 2.598 1.00
23_R 37_E 2.595 1.00
183_Q 186_K 2.465 1.00
12_V 44_A 2.452 1.00
40_D 64_G 2.405 1.00
157_R 160_D 2.381 1.00
65_M 73_A 2.325 1.00
92_S 112_D 2.259 1.00
23_R 27_E 2.224 1.00
36_A 53_I 2.216 1.00
158_E 195_K 2.213 1.00
41_G 65_M 2.184 1.00
95_V 115_V 2.16 1.00
171_N 186_K 2.126 1.00
25_L 113_P 2.056 1.00
40_D 43_S 2.044 1.00
45_I 73_A 1.981 1.00
8_Q 33_E 1.915 1.00
49_N 77_D 1.888 1.00
66_S 69_D 1.888 1.00
188_H 191_N 1.842 1.00
39_G 43_S 1.813 1.00
38_A 47_L 1.806 1.00
163_H 167_Q 1.801 1.00
71_L 83_I 1.716 1.00
84_I 123_G 1.71 1.00
55_V 120_I 1.709 1.00
26_L 120_I 1.707 1.00
85_I 98_L 1.696 1.00
8_Q 36_A 1.658 1.00
58_L 70_T 1.655 1.00
170_S 173_Q 1.654 1.00
61_N 89_S 1.642 1.00
60_L 85_I 1.618 1.00
100_D 121_R 1.614 1.00
104_D 126_G 1.581 1.00
36_A 47_L 1.58 1.00
58_L 71_L 1.562 1.00
29_D 117_L 1.537 1.00
36_A 51_L 1.527 1.00
71_L 85_I 1.525 1.00
10_M 38_A 1.521 1.00
145_G 150_P 1.517 1.00
85_I 103_A 1.479 1.00
73_A 76_R 1.465 1.00
89_S 94_D 1.452 1.00
13_D 19_R 1.444 1.00
56_I 81_A 1.434 1.00
12_V 62_M 1.425 1.00
65_M 69_D 1.41 1.00
164_E 174_I 1.409 1.00
41_G 70_T 1.401 0.99
75_R 104_D 1.362 0.99
45_I 70_T 1.358 0.99
105_G 119_A 1.347 0.99
68_L 101_A 1.329 0.99
144_F 160_D 1.297 0.99
169_L 177_V 1.296 0.99
164_E 177_V 1.267 0.99
47_L 51_L 1.257 0.99
60_L 68_L 1.257 0.99
42_A 65_M 1.257 0.99
162_L 204_A 1.251 0.99
171_N 175_A 1.244 0.98
69_D 72_N 1.235 0.98
46_D 50_R 1.234 0.98
73_A 77_D 1.234 0.98
184_T 188_H 1.209 0.98
47_L 50_R 1.203 0.98
32_S 121_R 1.201 0.98
189_I 193_L 1.192 0.98
187_V 190_R 1.19 0.98
45_I 65_M 1.182 0.98
198_V 207_L 1.179 0.98
31_G 121_R 1.178 0.98
42_A 46_D 1.174 0.98
38_A 44_A 1.174 0.98
48_A 74_L 1.166 0.97
16_P 39_G 1.157 0.97
91_A 94_D 1.152 0.97
155_T 195_K 1.148 0.97
140_E 143_M 1.141 0.97
29_D 121_R 1.129 0.97
72_N 97_A 1.124 0.97
14_D 59_D 1.121 0.97
141_R 163_H 1.111 0.96
55_V 124_A 1.108 0.96
43_S 46_D 1.096 0.96
9_V 32_S 1.094 0.96
62_M 70_T 1.084 0.96
44_A 48_A 1.078 0.95
93_S 97_A 1.073 0.95
160_D 163_H 1.057 0.95
123_G 126_G 1.055 0.95
22_V 86_L 1.046 0.94
68_L 97_A 1.036 0.94
43_S 47_L 1.035 0.94
183_Q 187_V 1.024 0.93
164_E 169_L 1.017 0.93
172_K 176_S 1.013 0.93
12_V 56_I 1.01 0.93
22_V 116_L 1.009 0.93
137_Y 147_E 1.003 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3c3wA20.97211000.148Contact Map0.595
4gvpA40.96281000.161Contact Map0.782
1a04A20.99071000.162Contact Map0.685
4hyeA20.95351000.174Contact Map0.819
3kloA411000.184Contact Map0.427
1yioA10.94421000.216Contact Map0.689
4b09A120.9861000.216Contact Map0.66
1ys7A20.98141000.222Contact Map0.783
3q9sA10.96281000.228Contact Map0.693
1p2fA10.95351000.237Contact Map0.765

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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