| UniProt: | P52108 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13190 | ||
| Length: | 239 (226) | ||
| Sequences: | 27571 | ||
| Seq/Len: | 122.00 |
| RSTA
Paralog alert: 0.94 [within 20: 0.55] - ratio of genomes with paralogs Cluster includes: ARCA BAER BASR BGLJ CPXR CREB CSGD CUSR DCUR DPIA EVGA FIMZ KDPE NARL NARP OMPR PHOB PHOP QSEB RCSB RSTA TORR UHPA UVRY YEDW YGEK YHJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 14_G | 30_V | 3.58 | 1.00 | |
| 14_G | 32_P | 2.81 | 1.00 | |
| 35_D | 57_G | 2.638 | 1.00 | |
| 7_V | 37_A | 2.575 | 1.00 | |
| 33_R | 57_G | 2.532 | 1.00 | |
| 18_A | 30_V | 2.477 | 1.00 | |
| 29_T | 46_P | 2.392 | 1.00 | |
| 58_K | 66_D | 2.382 | 1.00 | |
| 183_R | 203_D | 2.38 | 1.00 | |
| 200_R | 203_D | 2.367 | 1.00 | |
| 165_A | 168_E | 2.277 | 1.00 | |
| 18_A | 22_A | 2.269 | 1.00 | |
| 84_D | 104_P | 2.268 | 1.00 | |
| 34_G | 58_K | 2.152 | 1.00 | |
| 87_H | 107_V | 2.15 | 1.00 | |
| 166_D | 212_K | 2.145 | 1.00 | |
| 33_R | 36_Q | 2.118 | 1.00 | |
| 20_Y | 105_P | 2.014 | 1.00 | |
| 3_T | 27_Q | 2.006 | 1.00 | |
| 59_D | 62_T | 1.983 | 1.00 | |
| 38_E | 66_D | 1.963 | 1.00 | |
| 143_T | 156_A | 1.953 | 1.00 | |
| 32_P | 36_Q | 1.882 | 1.00 | |
| 224_K | 234_A | 1.859 | 1.00 | |
| 3_T | 29_T | 1.843 | 1.00 | |
| 171_W | 175_T | 1.829 | 1.00 | |
| 31_E | 40_T | 1.827 | 1.00 | |
| 48_L | 112_L | 1.809 | 1.00 | |
| 53_I | 77_L | 1.799 | 1.00 | |
| 140_H | 145_T | 1.796 | 1.00 | |
| 77_L | 90_A | 1.789 | 1.00 | |
| 205_A | 208_R | 1.771 | 1.00 | |
| 224_K | 232_L | 1.766 | 1.00 | |
| 152_V | 159_E | 1.735 | 1.00 | |
| 21_L | 112_L | 1.717 | 1.00 | |
| 146_I | 174_A | 1.715 | 1.00 | |
| 51_L | 63_I | 1.702 | 1.00 | |
| 92_E | 113_R | 1.698 | 1.00 | |
| 64_C | 75_I | 1.69 | 1.00 | |
| 76_V | 115_H | 1.683 | 1.00 | |
| 51_L | 64_C | 1.672 | 1.00 | |
| 96_C | 118_Q | 1.651 | 1.00 | |
| 172_E | 186_L | 1.637 | 1.00 | |
| 54_M | 81_L | 1.62 | 1.00 | |
| 42_L | 70_K | 1.608 | 1.00 | |
| 176_H | 179_Q | 1.579 | 1.00 | |
| 145_T | 154_T | 1.576 | 1.00 | |
| 7_V | 55_L | 1.556 | 1.00 | |
| 5_V | 31_E | 1.524 | 1.00 | |
| 24_H | 109_L | 1.523 | 1.00 | |
| 66_D | 69_A | 1.517 | 1.00 | |
| 97_D | 111_R | 1.516 | 1.00 | |
| 172_E | 189_N | 1.515 | 1.00 | |
| 81_L | 86_N | 1.512 | 1.00 | |
| 64_C | 77_L | 1.508 | 1.00 | |
| 49_V | 73_G | 1.501 | 1.00 | |
| 77_L | 95_A | 1.468 | 1.00 | |
| 8_E | 14_G | 1.449 | 1.00 | |
| 38_E | 63_I | 1.436 | 1.00 | |
| 34_G | 63_I | 1.413 | 1.00 | |
| 182_D | 185_A | 1.404 | 0.99 | |
| 58_K | 62_T | 1.401 | 0.99 | |
| 29_T | 40_T | 1.398 | 0.99 | |
| 61_M | 93_M | 1.354 | 0.99 | |
| 68_R | 96_C | 1.342 | 0.99 | |
| 147_D | 150_N | 1.325 | 0.99 | |
| 53_I | 61_M | 1.306 | 0.99 | |
| 62_T | 65_R | 1.301 | 0.99 | |
| 177_A | 181_M | 1.301 | 0.99 | |
| 39_E | 43_R | 1.263 | 0.99 | |
| 206_I | 210_R | 1.262 | 0.99 | |
| 35_D | 58_K | 1.259 | 0.99 | |
| 40_T | 44_E | 1.258 | 0.99 | |
| 40_T | 43_R | 1.257 | 0.99 | |
| 226_V | 232_L | 1.226 | 0.98 | |
| 151_R | 168_E | 1.224 | 0.98 | |
| 41_I | 67_L | 1.223 | 0.98 | |
| 48_L | 116_L | 1.213 | 0.98 | |
| 172_E | 181_M | 1.207 | 0.98 | |
| 35_D | 39_E | 1.205 | 0.98 | |
| 26_M | 113_R | 1.191 | 0.98 | |
| 31_E | 37_A | 1.184 | 0.98 | |
| 181_M | 189_N | 1.181 | 0.98 | |
| 83_S | 86_N | 1.158 | 0.97 | |
| 201_S | 205_A | 1.153 | 0.97 | |
| 11_A | 32_P | 1.152 | 0.97 | |
| 38_E | 58_K | 1.147 | 0.97 | |
| 36_Q | 39_E | 1.147 | 0.97 | |
| 148_P | 171_W | 1.147 | 0.97 | |
| 115_H | 118_Q | 1.144 | 0.97 | |
| 65_R | 89_L | 1.135 | 0.97 | |
| 151_R | 229_K | 1.128 | 0.97 | |
| 25_D | 113_R | 1.127 | 0.97 | |
| 29_T | 44_E | 1.122 | 0.97 | |
| 24_H | 113_R | 1.113 | 0.96 | |
| 204_V | 207_S | 1.107 | 0.96 | |
| 184_D | 199_D | 1.098 | 0.96 | |
| 54_M | 80_S | 1.096 | 0.96 | |
| 17_I | 78_L | 1.095 | 0.96 | |
| 6_F | 28_V | 1.093 | 0.96 | |
| 179_Q | 185_A | 1.083 | 0.96 | |
| 7_V | 49_V | 1.078 | 0.95 | |
| 37_A | 41_I | 1.077 | 0.95 | |
| 154_T | 159_E | 1.072 | 0.95 | |
| 9_D | 52_D | 1.071 | 0.95 | |
| 146_I | 167_F | 1.069 | 0.95 | |
| 216_N | 219_E | 1.064 | 0.95 | |
| 4_I | 26_M | 1.064 | 0.95 | |
| 5_V | 37_A | 1.055 | 0.95 | |
| 36_Q | 40_T | 1.053 | 0.95 | |
| 138_A | 145_T | 1.05 | 0.94 | |
| 85_M | 89_L | 1.047 | 0.94 | |
| 88_I | 106_A | 1.046 | 0.94 | |
| 55_L | 63_I | 1.046 | 0.94 | |
| 5_V | 46_P | 1.042 | 0.94 | |
| 163_S | 212_K | 1.035 | 0.94 | |
| 84_D | 88_I | 1.026 | 0.94 | |
| 149_I | 179_Q | 1.017 | 0.93 | |
| 40_T | 46_P | 1.015 | 0.93 | |
| 172_E | 176_H | 1.014 | 0.93 | |
| 49_V | 67_L | 1.008 | 0.93 | |
| 8_E | 55_L | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2gwrA | 1 | 0.9498 | 100 | 0.146 | Contact Map | 0.684 |
| 1ys7A | 2 | 0.9456 | 100 | 0.156 | Contact Map | 0.777 |
| 2oqrA | 1 | 0.9498 | 100 | 0.159 | Contact Map | 0.572 |
| 3r0jA | 2 | 0.9498 | 100 | 0.162 | Contact Map | 0.687 |
| 4b09A | 12 | 0.9582 | 100 | 0.187 | Contact Map | 0.682 |
| 1kgsA | 1 | 0.9331 | 100 | 0.196 | Contact Map | 0.732 |
| 1p2fA | 1 | 0.9121 | 100 | 0.212 | Contact Map | 0.751 |
| 2hqrA | 2 | 0.9121 | 100 | 0.214 | Contact Map | 0.685 |
| 3q9sA | 1 | 0.8912 | 100 | 0.23 | Contact Map | 0.668 |
| 3c3wA | 2 | 0.8954 | 100 | 0.312 | Contact Map | 0.631 |
Sequence Conservation (Image Generated using WebLogo v3)