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OPENSEQ.org

OMPR - Transcriptional regulatory protein OmpR
UniProt: P0AA16 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10672
Length: 239 (229)
Sequences: 27431
Seq/Len: 119.79

OMPR
Paralog alert: 0.93 [within 20: 0.54] - ratio of genomes with paralogs
Cluster includes: ARCA BAER BASR BGLJ CPXR CREB CSGD CUSR DCUR DPIA EVGA FIMZ KDPE NARL NARP OMPR PHOB PHOP QSEB RCSB RSTA TORR UHPA UVRY YEDW YGEK YHJB
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
17_R 33_S 3.537 1.00
17_R 35_A 2.797 1.00
38_E 60_G 2.565 1.00
21_E 33_S 2.553 1.00
10_V 40_M 2.472 1.00
36_N 60_G 2.467 1.00
164_G 167_A 2.374 1.00
182_R 202_D 2.372 1.00
32_R 49_F 2.328 1.00
199_R 202_D 2.314 1.00
61_E 69_R 2.306 1.00
165_E 211_M 2.294 1.00
88_E 108_N 2.289 1.00
21_E 25_T 2.274 1.00
37_A 61_E 2.148 1.00
36_N 39_Q 2.135 1.00
91_R 111_E 2.12 1.00
142_K 155_E 1.989 1.00
23_Y 109_P 1.965 1.00
6_K 30_Q 1.962 1.00
62_D 65_S 1.926 1.00
41_D 69_R 1.904 1.00
139_A 144_K 1.898 1.00
151_E 158_P 1.859 1.00
223_Q 233_V 1.849 1.00
170_K 174_S 1.835 1.00
35_A 39_Q 1.788 1.00
51_L 116_I 1.787 1.00
34_V 43_L 1.774 1.00
204_Q 207_R 1.756 1.00
81_M 94_G 1.747 1.00
145_L 173_V 1.736 1.00
6_K 32_R 1.736 1.00
223_Q 231_V 1.735 1.00
80_I 119_V 1.719 1.00
67_C 79_I 1.708 1.00
96_E 117_R 1.701 1.00
24_L 116_I 1.683 1.00
56_L 81_M 1.662 1.00
54_L 66_I 1.661 1.00
100_D 122_R 1.657 1.00
171_A 185_L 1.644 1.00
45_T 73_Q 1.639 1.00
54_L 67_C 1.614 1.00
57_M 85_K 1.602 1.00
175_H 179_P 1.601 1.00
175_H 178_E 1.579 1.00
144_K 153_F 1.579 1.00
8_L 34_V 1.548 1.00
67_C 81_M 1.529 1.00
69_R 72_S 1.523 1.00
171_A 188_L 1.518 1.00
27_Q 113_L 1.497 1.00
10_V 58_L 1.496 1.00
85_K 90_D 1.464 1.00
52_M 77_M 1.46 1.00
181_S 184_K 1.457 1.00
81_M 99_A 1.445 1.00
11_D 17_R 1.428 1.00
37_A 66_I 1.426 1.00
41_D 66_I 1.4 0.99
64_L 97_I 1.399 0.99
61_E 65_S 1.393 0.99
32_R 43_L 1.357 0.99
180_L 188_L 1.344 0.99
146_N 149_T 1.313 0.99
71_R 100_D 1.31 0.99
101_D 115_R 1.309 0.99
65_S 68_R 1.3 0.99
176_P 180_L 1.3 0.99
42_R 46_R 1.294 0.99
205_I 209_R 1.279 0.99
56_L 64_L 1.27 0.99
38_E 61_E 1.247 0.99
43_L 46_R 1.227 0.98
43_L 47_E 1.227 0.98
150_R 167_A 1.219 0.98
171_A 180_L 1.216 0.98
29_F 117_R 1.216 0.98
225_V 231_V 1.215 0.98
51_L 120_L 1.212 0.98
38_E 42_R 1.186 0.98
119_V 122_R 1.178 0.98
41_D 61_E 1.17 0.97
28_G 117_R 1.163 0.97
87_E 90_D 1.163 0.97
200_S 204_Q 1.162 0.97
145_L 166_F 1.157 0.97
69_R 73_Q 1.156 0.97
34_V 40_M 1.156 0.97
147_L 170_K 1.15 0.97
178_E 184_K 1.143 0.97
44_L 70_L 1.14 0.97
68_R 93_V 1.126 0.97
150_R 228_L 1.12 0.96
162_T 211_M 1.117 0.96
153_F 158_P 1.116 0.96
39_Q 42_R 1.115 0.96
203_V 206_S 1.105 0.96
7_I 29_F 1.099 0.96
164_G 190_R 1.099 0.96
14_M 35_A 1.096 0.96
137_V 144_K 1.084 0.96
183_D 187_N 1.075 0.95
10_V 52_M 1.075 0.95
20_L 82_V 1.074 0.95
12_D 55_D 1.073 0.95
32_R 47_E 1.062 0.95
40_M 44_L 1.062 0.95
92_I 110_R 1.06 0.95
57_M 84_A 1.058 0.95
8_L 40_M 1.057 0.95
64_L 93_V 1.054 0.95
183_D 198_E 1.053 0.95
89_V 93_V 1.05 0.94
148_G 178_E 1.049 0.94
9_V 31_V 1.043 0.94
27_Q 117_R 1.031 0.94
11_D 58_L 1.024 0.93
58_L 66_I 1.024 0.93
39_Q 43_L 1.022 0.93
8_L 49_F 1.022 0.93
20_L 112_L 1.019 0.93
118_A 123_Q 1.015 0.93
45_T 74_S 1.014 0.93
140_F 232_F 1.008 0.93
88_E 92_I 1.007 0.93
52_M 70_L 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1ys7A20.96231000.127Contact Map0.763
2gwrA10.96651000.132Contact Map0.68
3r0jA20.96231000.137Contact Map0.676
2oqrA10.96231000.141Contact Map0.559
1kgsA10.94141000.166Contact Map0.708
4b09A120.97491000.172Contact Map0.672
2hqrA20.92051000.181Contact Map0.666
1p2fA10.92051000.183Contact Map0.738
3q9sA10.89961000.198Contact Map0.676
3c3wA20.89961000.293Contact Map0.633

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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