| UniProt: | P52106 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13410 | ||
| Length: | 216 (203) | ||
| Sequences: | 29865 | ||
| Seq/Len: | 147.12 |
| CSGD
Paralog alert: 0.94 [within 20: 0.58] - ratio of genomes with paralogs Cluster includes: ARCA BAER BASR BGLJ CPXR CREB CSGD CUSR DCUR DPIA EVGA FIMZ KDPE NARL NARP OMPR PHOB PHOP QSEB RCSB RSTA TORR UHPA UVRY YEDW YGEK YHJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 23_A | 40_L | 3.236 | 1.00 | |
| 44_Q | 64_D | 2.7 | 1.00 | |
| 16_I | 46_S | 2.483 | 1.00 | |
| 23_A | 42_N | 2.48 | 1.00 | |
| 65_K | 74_T | 2.423 | 1.00 | |
| 159_R | 162_E | 2.412 | 1.00 | |
| 93_Y | 113_D | 2.355 | 1.00 | |
| 27_L | 31_K | 2.33 | 1.00 | |
| 173_N | 188_K | 2.321 | 1.00 | |
| 39_K | 53_G | 2.287 | 1.00 | |
| 185_N | 188_K | 2.27 | 1.00 | |
| 43_I | 65_K | 2.257 | 1.00 | |
| 96_R | 116_R | 2.246 | 1.00 | |
| 160_E | 197_K | 2.171 | 1.00 | |
| 29_H | 114_Q | 2.107 | 1.00 | |
| 47_L | 74_T | 2.092 | 1.00 | |
| 12_T | 37_T | 2.015 | 1.00 | |
| 66_K | 69_H | 1.977 | 1.00 | |
| 165_N | 169_I | 1.945 | 1.00 | |
| 27_L | 40_L | 1.866 | 1.00 | |
| 12_T | 39_K | 1.846 | 1.00 | |
| 142_H | 150_S | 1.838 | 1.00 | |
| 30_L | 121_L | 1.804 | 1.00 | |
| 190_H | 193_N | 1.802 | 1.00 | |
| 72_Q | 84_I | 1.795 | 1.00 | |
| 55_I | 121_L | 1.793 | 1.00 | |
| 86_L | 99_E | 1.785 | 1.00 | |
| 85_L | 124_V | 1.751 | 1.00 | |
| 58_L | 71_W | 1.703 | 1.00 | |
| 61_M | 90_P | 1.67 | 1.00 | |
| 101_W | 122_Q | 1.655 | 1.00 | |
| 166_K | 179_S | 1.651 | 1.00 | |
| 60_M | 86_L | 1.636 | 1.00 | |
| 166_K | 176_I | 1.627 | 1.00 | |
| 58_L | 72_Q | 1.609 | 1.00 | |
| 72_Q | 86_L | 1.6 | 1.00 | |
| 172_S | 175_E | 1.592 | 1.00 | |
| 74_T | 77_R | 1.578 | 1.00 | |
| 105_N | 127_G | 1.574 | 1.00 | |
| 17_T | 23_A | 1.529 | 1.00 | |
| 65_K | 69_H | 1.503 | 1.00 | |
| 200_V | 209_W | 1.501 | 1.00 | |
| 86_L | 104_I | 1.501 | 1.00 | |
| 171_A | 179_S | 1.482 | 1.00 | |
| 56_I | 82_I | 1.48 | 1.00 | |
| 90_P | 95_Y | 1.479 | 1.00 | |
| 43_I | 71_W | 1.461 | 1.00 | |
| 47_L | 71_W | 1.449 | 1.00 | |
| 16_I | 62_E | 1.427 | 1.00 | |
| 76_S | 105_N | 1.409 | 1.00 | |
| 39_K | 49_D | 1.405 | 0.99 | |
| 106_G | 120_G | 1.397 | 0.99 | |
| 68_I | 102_P | 1.352 | 0.99 | |
| 42_N | 45_R | 1.348 | 0.99 | |
| 23_A | 41_H | 1.335 | 0.99 | |
| 69_H | 73_D | 1.334 | 0.99 | |
| 44_Q | 65_K | 1.312 | 0.99 | |
| 60_M | 68_I | 1.308 | 0.99 | |
| 74_T | 78_K | 1.299 | 0.99 | |
| 41_H | 49_D | 1.288 | 0.99 | |
| 166_K | 171_A | 1.281 | 0.99 | |
| 44_Q | 48_D | 1.271 | 0.99 | |
| 35_A | 122_Q | 1.269 | 0.99 | |
| 47_L | 65_K | 1.266 | 0.99 | |
| 92_D | 95_Y | 1.254 | 0.99 | |
| 36_I | 122_Q | 1.249 | 0.99 | |
| 50_I | 75_L | 1.228 | 0.98 | |
| 73_D | 98_I | 1.228 | 0.98 | |
| 14_L | 41_H | 1.216 | 0.98 | |
| 157_T | 197_K | 1.211 | 0.98 | |
| 46_S | 50_I | 1.2 | 0.98 | |
| 34_L | 118_V | 1.199 | 0.98 | |
| 189_T | 192_Y | 1.194 | 0.98 | |
| 55_I | 125_L | 1.181 | 0.98 | |
| 27_L | 41_H | 1.181 | 0.98 | |
| 164_L | 206_A | 1.181 | 0.98 | |
| 186_T | 190_H | 1.174 | 0.98 | |
| 18_K | 59_D | 1.171 | 0.98 | |
| 174_N | 184_E | 1.168 | 0.97 | |
| 191_L | 195_F | 1.16 | 0.97 | |
| 174_N | 178_R | 1.159 | 0.97 | |
| 13_L | 36_I | 1.154 | 0.97 | |
| 148_Y | 162_E | 1.15 | 0.97 | |
| 209_W | 213_N | 1.146 | 0.97 | |
| 94_P | 98_I | 1.144 | 0.97 | |
| 171_A | 175_E | 1.121 | 0.97 | |
| 162_E | 165_N | 1.105 | 0.96 | |
| 20_S | 42_N | 1.102 | 0.96 | |
| 26_L | 87_L | 1.1 | 0.96 | |
| 45_R | 49_D | 1.098 | 0.96 | |
| 14_L | 46_S | 1.098 | 0.96 | |
| 39_K | 51_S | 1.097 | 0.96 | |
| 124_V | 127_G | 1.079 | 0.95 | |
| 145_N | 165_N | 1.077 | 0.95 | |
| 61_M | 89_T | 1.077 | 0.95 | |
| 17_T | 62_E | 1.074 | 0.95 | |
| 68_I | 98_I | 1.073 | 0.95 | |
| 97_D | 115_E | 1.072 | 0.95 | |
| 16_I | 56_I | 1.069 | 0.95 | |
| 45_R | 48_D | 1.067 | 0.95 | |
| 49_D | 53_G | 1.059 | 0.95 | |
| 62_E | 71_W | 1.052 | 0.95 | |
| 123_G | 128_E | 1.049 | 0.94 | |
| 161_K | 165_N | 1.043 | 0.94 | |
| 175_E | 179_S | 1.041 | 0.94 | |
| 14_L | 53_G | 1.038 | 0.94 | |
| 26_L | 117_V | 1.023 | 0.93 | |
| 15_L | 38_G | 1.02 | 0.93 | |
| 93_Y | 97_D | 1.013 | 0.93 | |
| 14_L | 49_D | 1.011 | 0.93 | |
| 56_I | 75_L | 1.007 | 0.93 | |
| 185_N | 189_T | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3c3wA | 2 | 0.9537 | 100 | 0.118 | Contact Map | 0.59 |
| 4gvpA | 4 | 0.9398 | 100 | 0.137 | Contact Map | 0.762 |
| 1a04A | 2 | 0.9722 | 100 | 0.151 | Contact Map | 0.683 |
| 3kloA | 4 | 0.9769 | 100 | 0.156 | Contact Map | 0.504 |
| 4hyeA | 2 | 0.9491 | 100 | 0.158 | Contact Map | 0.802 |
| 1yioA | 1 | 0.9259 | 100 | 0.192 | Contact Map | 0.698 |
| 4b09A | 12 | 0.9861 | 100 | 0.197 | Contact Map | 0.652 |
| 1ys7A | 2 | 0.9769 | 100 | 0.199 | Contact Map | 0.748 |
| 2gwrA | 1 | 0.9537 | 100 | 0.224 | Contact Map | 0.645 |
| 3q9sA | 1 | 0.9722 | 100 | 0.226 | Contact Map | 0.659 |
Sequence Conservation (Image Generated using WebLogo v3)