| UniProt: | P0ACZ8 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13851 | ||
| Length: | 227 (223) | ||
| Sequences: | 27987 | ||
| Seq/Len: | 125.50 |
| CUSR
Paralog alert: 0.94 [within 20: 0.55] - ratio of genomes with paralogs Cluster includes: ARCA BAER BASR BGLJ CPXR CREB CSGD CUSR DCUR DPIA EVGA FIMZ KDPE NARL NARP OMPR PHOB PHOP QSEB RCSB RSTA TORR UHPA UVRY YEDW YGEK YHJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 13_G | 29_L | 3.523 | 1.00 | |
| 13_G | 31_D | 2.768 | 1.00 | |
| 17_T | 29_L | 2.614 | 1.00 | |
| 34_L | 56_D | 2.58 | 1.00 | |
| 6_V | 36_G | 2.489 | 1.00 | |
| 32_N | 56_D | 2.441 | 1.00 | |
| 172_R | 192_D | 2.346 | 1.00 | |
| 57_V | 65_M | 2.334 | 1.00 | |
| 154_K | 157_T | 2.316 | 1.00 | |
| 28_D | 45_Y | 2.311 | 1.00 | |
| 189_N | 192_D | 2.305 | 1.00 | |
| 17_T | 21_T | 2.255 | 1.00 | |
| 84_I | 104_A | 2.216 | 1.00 | |
| 155_E | 201_K | 2.196 | 1.00 | |
| 32_N | 35_N | 2.085 | 1.00 | |
| 33_G | 57_V | 2.08 | 1.00 | |
| 41_M | 69_A | 2.047 | 1.00 | |
| 87_R | 107_E | 2.037 | 1.00 | |
| 37_Y | 65_M | 1.964 | 1.00 | |
| 19_G | 105_F | 1.951 | 1.00 | |
| 2_K | 26_V | 1.942 | 1.00 | |
| 132_D | 145_S | 1.913 | 1.00 | |
| 58_N | 61_D | 1.906 | 1.00 | |
| 212_Q | 222_E | 1.865 | 1.00 | |
| 31_D | 35_N | 1.849 | 1.00 | |
| 160_E | 164_R | 1.828 | 1.00 | |
| 129_Q | 134_M | 1.825 | 1.00 | |
| 141_K | 148_R | 1.802 | 1.00 | |
| 30_A | 39_L | 1.778 | 1.00 | |
| 2_K | 28_D | 1.77 | 1.00 | |
| 47_L | 112_V | 1.769 | 1.00 | |
| 77_L | 90_G | 1.737 | 1.00 | |
| 212_Q | 220_M | 1.728 | 1.00 | |
| 63_V | 75_I | 1.713 | 1.00 | |
| 76_L | 115_L | 1.711 | 1.00 | |
| 20_L | 112_V | 1.708 | 1.00 | |
| 194_A | 197_R | 1.707 | 1.00 | |
| 161_F | 175_I | 1.662 | 1.00 | |
| 135_V | 163_L | 1.66 | 1.00 | |
| 50_L | 62_I | 1.659 | 1.00 | |
| 52_I | 77_L | 1.626 | 1.00 | |
| 53_M | 81_L | 1.613 | 1.00 | |
| 96_D | 118_R | 1.6 | 1.00 | |
| 165_H | 168_E | 1.595 | 1.00 | |
| 92_E | 113_R | 1.586 | 1.00 | |
| 50_L | 63_V | 1.567 | 1.00 | |
| 161_F | 178_Q | 1.563 | 1.00 | |
| 4_L | 30_A | 1.539 | 1.00 | |
| 134_M | 143_T | 1.537 | 1.00 | |
| 65_M | 68_S | 1.53 | 1.00 | |
| 81_L | 86_H | 1.503 | 1.00 | |
| 63_V | 77_L | 1.487 | 1.00 | |
| 171_P | 174_L | 1.463 | 1.00 | |
| 6_V | 54_L | 1.46 | 1.00 | |
| 48_I | 73_M | 1.445 | 1.00 | |
| 77_L | 95_A | 1.428 | 1.00 | |
| 7_E | 13_G | 1.4 | 0.99 | |
| 67_R | 96_D | 1.4 | 0.99 | |
| 57_V | 61_D | 1.394 | 0.99 | |
| 37_Y | 62_I | 1.392 | 0.99 | |
| 33_G | 62_I | 1.388 | 0.99 | |
| 23_A | 109_L | 1.377 | 0.99 | |
| 28_D | 39_L | 1.373 | 0.99 | |
| 97_D | 111_R | 1.359 | 0.99 | |
| 60_W | 93_L | 1.349 | 0.99 | |
| 170_L | 178_Q | 1.348 | 0.99 | |
| 61_D | 64_R | 1.319 | 0.99 | |
| 195_V | 199_R | 1.299 | 0.99 | |
| 65_M | 69_A | 1.293 | 0.99 | |
| 34_L | 57_V | 1.284 | 0.99 | |
| 39_L | 42_T | 1.282 | 0.99 | |
| 38_H | 42_T | 1.273 | 0.99 | |
| 136_D | 139_S | 1.267 | 0.99 | |
| 52_I | 60_W | 1.266 | 0.99 | |
| 39_L | 43_G | 1.265 | 0.99 | |
| 166_Q | 170_L | 1.264 | 0.99 | |
| 24_G | 113_R | 1.228 | 0.98 | |
| 161_F | 170_L | 1.217 | 0.98 | |
| 214_V | 220_M | 1.214 | 0.98 | |
| 47_L | 116_L | 1.211 | 0.98 | |
| 25_F | 113_R | 1.206 | 0.98 | |
| 34_L | 38_H | 1.186 | 0.98 | |
| 40_A | 66_L | 1.176 | 0.98 | |
| 28_D | 43_G | 1.151 | 0.97 | |
| 140_R | 157_T | 1.15 | 0.97 | |
| 37_Y | 57_V | 1.145 | 0.97 | |
| 83_T | 86_H | 1.142 | 0.97 | |
| 137_L | 160_E | 1.133 | 0.97 | |
| 64_R | 89_K | 1.132 | 0.97 | |
| 140_R | 217_V | 1.124 | 0.97 | |
| 193_V | 196_K | 1.111 | 0.96 | |
| 35_N | 38_H | 1.111 | 0.96 | |
| 30_A | 36_G | 1.11 | 0.96 | |
| 8_D | 51_D | 1.107 | 0.96 | |
| 168_E | 174_L | 1.101 | 0.96 | |
| 10_K | 31_D | 1.101 | 0.96 | |
| 135_V | 156_F | 1.1 | 0.96 | |
| 3_L | 25_F | 1.099 | 0.96 | |
| 143_T | 148_R | 1.098 | 0.96 | |
| 190_A | 194_A | 1.096 | 0.96 | |
| 127_Q | 134_M | 1.094 | 0.96 | |
| 115_L | 118_R | 1.083 | 0.96 | |
| 173_S | 188_T | 1.078 | 0.95 | |
| 16_L | 78_L | 1.074 | 0.95 | |
| 53_M | 80_A | 1.071 | 0.95 | |
| 6_V | 48_I | 1.067 | 0.95 | |
| 152_T | 201_K | 1.059 | 0.95 | |
| 85_E | 89_K | 1.059 | 0.95 | |
| 35_N | 39_L | 1.056 | 0.95 | |
| 4_L | 45_Y | 1.049 | 0.94 | |
| 84_I | 88_V | 1.044 | 0.94 | |
| 5_I | 27_V | 1.042 | 0.94 | |
| 4_L | 36_G | 1.038 | 0.94 | |
| 36_G | 40_A | 1.034 | 0.94 | |
| 60_W | 89_K | 1.032 | 0.94 | |
| 161_F | 165_H | 1.025 | 0.93 | |
| 114_T | 119_G | 1.018 | 0.93 | |
| 88_V | 106_A | 1.013 | 0.93 | |
| 138_V | 168_E | 1.013 | 0.93 | |
| 4_L | 39_L | 1.005 | 0.93 | |
| 70_N | 73_M | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3r0jA | 2 | 0.9868 | 100 | 0.124 | Contact Map | 0.689 |
| 1ys7A | 2 | 0.9868 | 100 | 0.128 | Contact Map | 0.775 |
| 2gwrA | 1 | 0.9912 | 100 | 0.135 | Contact Map | 0.679 |
| 1kgsA | 1 | 0.9824 | 100 | 0.15 | Contact Map | 0.72 |
| 2hqrA | 2 | 0.9648 | 100 | 0.161 | Contact Map | 0.677 |
| 2oqrA | 1 | 0.978 | 100 | 0.162 | Contact Map | 0.576 |
| 4b09A | 12 | 0.9956 | 100 | 0.178 | Contact Map | 0.679 |
| 1p2fA | 1 | 0.9559 | 100 | 0.191 | Contact Map | 0.738 |
| 3q9sA | 1 | 0.9339 | 100 | 0.196 | Contact Map | 0.682 |
| 3c3wA | 2 | 0.9427 | 100 | 0.255 | Contact Map | 0.631 |
Sequence Conservation (Image Generated using WebLogo v3)