| UniProt: | P23836 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10731 | ||
| Length: | 223 (221) | ||
| Sequences: | 28481 | ||
| Seq/Len: | 128.87 |
| PHOP
Paralog alert: 0.94 [within 20: 0.56] - ratio of genomes with paralogs Cluster includes: ARCA BAER BASR BGLJ CPXR CREB CSGD CUSR DCUR DPIA EVGA FIMZ KDPE NARL NARP OMPR PHOB PHOP QSEB RCSB RSTA TORR UHPA UVRY YEDW YGEK YHJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 13_R | 29_D | 3.451 | 1.00 | |
| 13_R | 31_E | 2.805 | 1.00 | |
| 34_K | 56_D | 2.571 | 1.00 | |
| 6_V | 36_A | 2.547 | 1.00 | |
| 17_K | 29_D | 2.48 | 1.00 | |
| 188_H | 191_D | 2.445 | 1.00 | |
| 32_D | 56_D | 2.439 | 1.00 | |
| 153_F | 156_T | 2.351 | 1.00 | |
| 57_E | 65_R | 2.344 | 1.00 | |
| 171_K | 191_D | 2.333 | 1.00 | |
| 28_D | 45_P | 2.306 | 1.00 | |
| 17_K | 21_Q | 2.24 | 1.00 | |
| 84_W | 104_H | 2.185 | 1.00 | |
| 154_E | 200_K | 2.164 | 1.00 | |
| 33_A | 57_E | 2.159 | 1.00 | |
| 87_K | 107_E | 2.077 | 1.00 | |
| 32_D | 35_E | 2.066 | 1.00 | |
| 41_N | 69_N | 2.02 | 1.00 | |
| 37_D | 65_R | 1.98 | 1.00 | |
| 19_Q | 105_I | 1.977 | 1.00 | |
| 2_R | 26_Q | 1.945 | 1.00 | |
| 131_P | 144_N | 1.919 | 1.00 | |
| 211_T | 221_E | 1.885 | 1.00 | |
| 58_D | 61_S | 1.868 | 1.00 | |
| 31_E | 35_E | 1.844 | 1.00 | |
| 159_E | 163_R | 1.81 | 1.00 | |
| 77_V | 90_V | 1.805 | 1.00 | |
| 128_S | 133_Q | 1.786 | 1.00 | |
| 30_A | 39_Y | 1.781 | 1.00 | |
| 140_E | 147_V | 1.768 | 1.00 | |
| 211_T | 219_L | 1.757 | 1.00 | |
| 2_R | 28_D | 1.743 | 1.00 | |
| 193_L | 196_R | 1.736 | 1.00 | |
| 47_I | 112_M | 1.733 | 1.00 | |
| 20_I | 112_M | 1.731 | 1.00 | |
| 63_I | 75_I | 1.689 | 1.00 | |
| 50_V | 62_L | 1.658 | 1.00 | |
| 76_L | 115_L | 1.65 | 1.00 | |
| 96_D | 118_R | 1.634 | 1.00 | |
| 53_G | 81_R | 1.617 | 1.00 | |
| 52_L | 77_V | 1.611 | 1.00 | |
| 160_T | 174_L | 1.61 | 1.00 | |
| 50_V | 63_I | 1.588 | 1.00 | |
| 4_L | 30_A | 1.571 | 1.00 | |
| 133_Q | 142_S | 1.566 | 1.00 | |
| 92_S | 113_Q | 1.555 | 1.00 | |
| 134_V | 162_I | 1.55 | 1.00 | |
| 160_T | 177_Q | 1.549 | 1.00 | |
| 65_R | 68_S | 1.531 | 1.00 | |
| 63_I | 77_V | 1.523 | 1.00 | |
| 164_N | 167_K | 1.511 | 1.00 | |
| 81_R | 86_D | 1.488 | 1.00 | |
| 6_V | 54_L | 1.481 | 1.00 | |
| 77_V | 95_A | 1.47 | 1.00 | |
| 48_A | 73_L | 1.443 | 1.00 | |
| 170_S | 173_S | 1.432 | 1.00 | |
| 7_E | 13_R | 1.428 | 1.00 | |
| 33_A | 62_L | 1.416 | 1.00 | |
| 57_E | 61_S | 1.392 | 0.99 | |
| 67_R | 96_D | 1.389 | 0.99 | |
| 37_D | 62_L | 1.375 | 0.99 | |
| 165_N | 169_V | 1.372 | 0.99 | |
| 194_M | 198_R | 1.359 | 0.99 | |
| 23_A | 109_M | 1.354 | 0.99 | |
| 28_D | 39_Y | 1.338 | 0.99 | |
| 97_D | 111_R | 1.335 | 0.99 | |
| 60_L | 93_A | 1.311 | 0.99 | |
| 167_K | 177_Q | 1.3 | 0.99 | |
| 65_R | 69_N | 1.295 | 0.99 | |
| 61_S | 64_R | 1.288 | 0.99 | |
| 39_Y | 43_H | 1.265 | 0.99 | |
| 39_Y | 42_E | 1.261 | 0.99 | |
| 34_K | 57_E | 1.258 | 0.99 | |
| 135_D | 138_R | 1.253 | 0.99 | |
| 38_Y | 42_E | 1.251 | 0.99 | |
| 52_L | 60_L | 1.247 | 0.99 | |
| 213_V | 219_L | 1.23 | 0.98 | |
| 25_H | 113_Q | 1.212 | 0.98 | |
| 24_G | 113_Q | 1.201 | 0.98 | |
| 34_K | 38_Y | 1.197 | 0.98 | |
| 83_S | 86_D | 1.17 | 0.97 | |
| 40_L | 66_W | 1.169 | 0.97 | |
| 47_I | 116_M | 1.164 | 0.97 | |
| 64_R | 89_E | 1.151 | 0.97 | |
| 139_R | 216_Q | 1.141 | 0.97 | |
| 37_D | 57_E | 1.137 | 0.97 | |
| 139_R | 156_T | 1.134 | 0.97 | |
| 10_A | 31_E | 1.131 | 0.97 | |
| 167_K | 173_S | 1.12 | 0.96 | |
| 30_A | 36_A | 1.119 | 0.96 | |
| 160_T | 169_V | 1.115 | 0.96 | |
| 35_E | 38_Y | 1.108 | 0.96 | |
| 8_D | 51_D | 1.108 | 0.96 | |
| 189_T | 193_L | 1.107 | 0.96 | |
| 136_L | 159_E | 1.104 | 0.96 | |
| 115_L | 118_R | 1.104 | 0.96 | |
| 192_V | 195_G | 1.093 | 0.96 | |
| 126_V | 133_Q | 1.09 | 0.96 | |
| 53_G | 80_A | 1.085 | 0.96 | |
| 28_D | 43_H | 1.079 | 0.95 | |
| 3_V | 25_H | 1.079 | 0.95 | |
| 16_L | 78_L | 1.074 | 0.95 | |
| 172_D | 187_S | 1.072 | 0.95 | |
| 160_T | 164_N | 1.071 | 0.95 | |
| 142_S | 147_V | 1.07 | 0.95 | |
| 85_Q | 89_E | 1.07 | 0.95 | |
| 60_L | 89_E | 1.063 | 0.95 | |
| 153_F | 179_Y | 1.063 | 0.95 | |
| 6_V | 48_A | 1.058 | 0.95 | |
| 54_L | 62_L | 1.056 | 0.95 | |
| 4_L | 36_A | 1.054 | 0.95 | |
| 4_L | 45_P | 1.051 | 0.94 | |
| 151_T | 200_K | 1.05 | 0.94 | |
| 134_V | 155_Y | 1.048 | 0.94 | |
| 5_V | 27_V | 1.039 | 0.94 | |
| 172_D | 176_L | 1.024 | 0.93 | |
| 84_W | 88_V | 1.022 | 0.93 | |
| 114_A | 119_N | 1.021 | 0.93 | |
| 35_E | 39_Y | 1.02 | 0.93 | |
| 88_V | 106_E | 1.011 | 0.93 | |
| 129_L | 220_F | 1.007 | 0.93 | |
| 188_H | 192_V | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3r0jA | 2 | 0.9955 | 100 | 0.127 | Contact Map | 0.695 |
| 1ys7A | 2 | 1 | 100 | 0.129 | Contact Map | 0.776 |
| 2gwrA | 1 | 0.9955 | 100 | 0.132 | Contact Map | 0.672 |
| 1kgsA | 1 | 1 | 100 | 0.15 | Contact Map | 0.719 |
| 2oqrA | 1 | 0.991 | 100 | 0.159 | Contact Map | 0.579 |
| 2hqrA | 2 | 0.9686 | 100 | 0.16 | Contact Map | 0.683 |
| 4b09A | 12 | 0.9955 | 100 | 0.165 | Contact Map | 0.662 |
| 1p2fA | 1 | 0.9641 | 100 | 0.187 | Contact Map | 0.747 |
| 3q9sA | 1 | 0.9507 | 100 | 0.193 | Contact Map | 0.693 |
| 4hyeA | 2 | 0.8834 | 100 | 0.269 | Contact Map | 0.81 |
Sequence Conservation (Image Generated using WebLogo v3)