| UniProt: | P0AFJ5 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10728 | ||
| Length: | 229 (222) | ||
| Sequences: | 27877 | ||
| Seq/Len: | 125.57 |
| PHOB
Paralog alert: 0.94 [within 20: 0.57] - ratio of genomes with paralogs Cluster includes: ARCA BAER BASR BGLJ CPXR CREB CSGD CUSR DCUR DPIA EVGA FIMZ KDPE NARL NARP OMPR PHOB PHOP QSEB RCSB RSTA TORR UHPA UVRY YEDW YGEK YHJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 15_R | 31_E | 3.456 | 1.00 | |
| 15_R | 33_E | 2.818 | 1.00 | |
| 36_D | 58_G | 2.548 | 1.00 | |
| 19_C | 31_E | 2.489 | 1.00 | |
| 8_V | 38_A | 2.408 | 1.00 | |
| 34_D | 58_G | 2.406 | 1.00 | |
| 158_T | 161_K | 2.393 | 1.00 | |
| 59_G | 67_H | 2.303 | 1.00 | |
| 30_V | 47_P | 2.294 | 1.00 | |
| 19_C | 23_E | 2.286 | 1.00 | |
| 159_E | 205_A | 2.264 | 1.00 | |
| 88_E | 108_S | 2.243 | 1.00 | |
| 193_R | 196_D | 2.241 | 1.00 | |
| 176_R | 196_D | 2.188 | 1.00 | |
| 34_D | 37_S | 2.113 | 1.00 | |
| 35_Y | 59_G | 2.11 | 1.00 | |
| 43_N | 71_E | 2.043 | 1.00 | |
| 91_R | 111_E | 2.032 | 1.00 | |
| 4_R | 28_Q | 1.992 | 1.00 | |
| 39_V | 67_H | 1.976 | 1.00 | |
| 21_V | 109_P | 1.944 | 1.00 | |
| 136_G | 149_G | 1.869 | 1.00 | |
| 60_S | 63_Q | 1.866 | 1.00 | |
| 133_E | 138_S | 1.844 | 1.00 | |
| 164_H | 168_T | 1.833 | 1.00 | |
| 33_E | 37_S | 1.817 | 1.00 | |
| 145_R | 152_P | 1.806 | 1.00 | |
| 216_Q | 226_S | 1.794 | 1.00 | |
| 49_L | 116_I | 1.767 | 1.00 | |
| 198_H | 201_R | 1.744 | 1.00 | |
| 81_M | 94_G | 1.735 | 1.00 | |
| 32_A | 41_Q | 1.731 | 1.00 | |
| 4_R | 30_V | 1.728 | 1.00 | |
| 80_V | 119_V | 1.726 | 1.00 | |
| 22_L | 116_I | 1.689 | 1.00 | |
| 65_I | 79_V | 1.67 | 1.00 | |
| 216_Q | 224_R | 1.656 | 1.00 | |
| 73_M | 77_I | 1.649 | 1.00 | |
| 165_F | 179_L | 1.642 | 1.00 | |
| 100_D | 122_R | 1.619 | 1.00 | |
| 139_L | 167_M | 1.612 | 1.00 | |
| 138_S | 147_M | 1.607 | 1.00 | |
| 96_E | 117_K | 1.596 | 1.00 | |
| 55_M | 85_R | 1.594 | 1.00 | |
| 52_L | 64_F | 1.562 | 1.00 | |
| 54_W | 81_M | 1.558 | 1.00 | |
| 52_L | 65_I | 1.553 | 1.00 | |
| 169_H | 172_R | 1.543 | 1.00 | |
| 67_H | 70_R | 1.528 | 1.00 | |
| 6_L | 32_A | 1.49 | 1.00 | |
| 50_I | 77_I | 1.461 | 1.00 | |
| 65_I | 81_M | 1.457 | 1.00 | |
| 85_R | 90_D | 1.449 | 1.00 | |
| 8_V | 56_L | 1.437 | 1.00 | |
| 35_Y | 64_F | 1.423 | 1.00 | |
| 81_M | 99_A | 1.422 | 1.00 | |
| 25_N | 113_V | 1.393 | 0.99 | |
| 175_S | 178_Q | 1.393 | 0.99 | |
| 59_G | 63_Q | 1.393 | 0.99 | |
| 69_K | 100_D | 1.374 | 0.99 | |
| 39_V | 64_F | 1.357 | 0.99 | |
| 9_E | 15_R | 1.348 | 0.99 | |
| 30_V | 41_Q | 1.348 | 0.99 | |
| 62_I | 97_T | 1.343 | 0.99 | |
| 165_F | 182_H | 1.332 | 0.99 | |
| 63_Q | 66_K | 1.299 | 0.99 | |
| 40_N | 44_E | 1.284 | 0.99 | |
| 170_P | 174_Y | 1.268 | 0.99 | |
| 67_H | 71_E | 1.267 | 0.99 | |
| 36_D | 59_G | 1.258 | 0.99 | |
| 73_M | 76_D | 1.256 | 0.99 | |
| 41_Q | 45_P | 1.244 | 0.98 | |
| 140_D | 143_S | 1.233 | 0.98 | |
| 54_W | 62_I | 1.233 | 0.98 | |
| 26_G | 117_K | 1.224 | 0.98 | |
| 41_Q | 44_E | 1.224 | 0.98 | |
| 101_D | 115_R | 1.222 | 0.98 | |
| 199_I | 203_R | 1.209 | 0.98 | |
| 27_F | 117_K | 1.206 | 0.98 | |
| 174_Y | 187_N | 1.206 | 0.98 | |
| 49_L | 120_M | 1.203 | 0.98 | |
| 165_F | 174_Y | 1.178 | 0.98 | |
| 218_V | 224_R | 1.177 | 0.98 | |
| 36_D | 40_N | 1.167 | 0.97 | |
| 39_V | 59_G | 1.155 | 0.97 | |
| 144_H | 161_K | 1.154 | 0.97 | |
| 194_T | 198_H | 1.151 | 0.97 | |
| 12_A | 33_E | 1.136 | 0.97 | |
| 172_R | 178_Q | 1.131 | 0.97 | |
| 119_V | 122_R | 1.125 | 0.97 | |
| 147_M | 152_P | 1.123 | 0.97 | |
| 87_E | 90_D | 1.123 | 0.97 | |
| 42_L | 68_L | 1.122 | 0.97 | |
| 141_P | 164_H | 1.107 | 0.96 | |
| 66_K | 93_R | 1.104 | 0.96 | |
| 37_S | 40_N | 1.099 | 0.96 | |
| 10_D | 53_D | 1.085 | 0.96 | |
| 32_A | 38_A | 1.081 | 0.95 | |
| 197_V | 200_R | 1.079 | 0.95 | |
| 89_E | 93_R | 1.077 | 0.95 | |
| 5_I | 27_F | 1.074 | 0.95 | |
| 156_G | 205_A | 1.068 | 0.95 | |
| 6_L | 47_P | 1.067 | 0.95 | |
| 139_L | 160_F | 1.062 | 0.95 | |
| 37_S | 41_Q | 1.061 | 0.95 | |
| 131_V | 138_S | 1.057 | 0.95 | |
| 208_P | 217_T | 1.054 | 0.95 | |
| 18_V | 82_L | 1.049 | 0.94 | |
| 92_V | 110_K | 1.04 | 0.94 | |
| 56_L | 64_F | 1.039 | 0.94 | |
| 177_E | 192_D | 1.037 | 0.94 | |
| 134_M | 225_F | 1.034 | 0.94 | |
| 210_G | 213_R | 1.033 | 0.94 | |
| 158_T | 184_W | 1.03 | 0.94 | |
| 6_L | 38_A | 1.03 | 0.94 | |
| 144_H | 221_T | 1.028 | 0.94 | |
| 8_V | 50_I | 1.027 | 0.94 | |
| 62_I | 93_R | 1.027 | 0.94 | |
| 7_V | 29_P | 1.021 | 0.93 | |
| 55_M | 84_A | 1.019 | 0.93 | |
| 177_E | 181_N | 1.018 | 0.93 | |
| 118_A | 123_I | 1.017 | 0.93 | |
| 142_T | 172_R | 1.01 | 0.93 | |
| 88_E | 92_V | 1.009 | 0.93 | |
| 30_V | 45_P | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1ys7A | 2 | 0.9869 | 100 | 0.133 | Contact Map | 0.768 |
| 2gwrA | 1 | 0.9825 | 100 | 0.142 | Contact Map | 0.674 |
| 3r0jA | 2 | 0.9869 | 100 | 0.147 | Contact Map | 0.691 |
| 2oqrA | 1 | 0.9782 | 100 | 0.148 | Contact Map | 0.577 |
| 1kgsA | 1 | 0.9825 | 100 | 0.164 | Contact Map | 0.723 |
| 4b09A | 12 | 0.9869 | 100 | 0.17 | Contact Map | 0.67 |
| 1p2fA | 1 | 0.952 | 100 | 0.184 | Contact Map | 0.73 |
| 3q9sA | 1 | 0.9345 | 100 | 0.188 | Contact Map | 0.693 |
| 2hqrA | 2 | 0.9476 | 100 | 0.191 | Contact Map | 0.67 |
| 3c3wA | 2 | 0.9301 | 100 | 0.262 | Contact Map | 0.61 |
Sequence Conservation (Image Generated using WebLogo v3)