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TORR - TorCAD operon transcriptional regulatory protein TorR
UniProt: P38684 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12615
Length: 230 (221)
Sequences: 28103
Seq/Len: 127.16

TORR
Paralog alert: 0.94 [within 20: 0.55] - ratio of genomes with paralogs
Cluster includes: ARCA BAER BASR BGLJ CPXR CREB CSGD CUSR DCUR DPIA EVGA FIMZ KDPE NARL NARP OMPR PHOB PHOP QSEB RCSB RSTA TORR UHPA UVRY YEDW YGEK YHJB
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
15_Q 31_V 3.585 1.00
15_Q 33_A 2.801 1.00
19_Q 31_V 2.619 1.00
36_A 58_D 2.615 1.00
8_V 38_L 2.538 1.00
34_S 58_D 2.457 1.00
197_R 200_D 2.377 1.00
59_E 67_A 2.365 1.00
179_R 200_D 2.342 1.00
161_A 164_E 2.319 1.00
30_S 47_V 2.298 1.00
85_R 105_E 2.247 1.00
19_Q 23_T 2.227 1.00
162_E 209_K 2.15 1.00
88_R 108_E 2.132 1.00
35_G 59_E 2.121 1.00
34_S 37_G 2.069 1.00
39_R 67_A 1.994 1.00
21_Y 106_L 1.989 1.00
4_H 28_T 1.968 1.00
139_G 152_D 1.926 1.00
60_N 63_M 1.892 1.00
216_V 226_A 1.88 1.00
33_A 37_G 1.836 1.00
4_H 30_S 1.823 1.00
167_V 171_T 1.806 1.00
32_T 41_I 1.798 1.00
136_R 141_C 1.794 1.00
78_L 91_G 1.782 1.00
216_V 224_F 1.752 1.00
49_L 113_V 1.744 1.00
22_F 113_V 1.726 1.00
202_L 205_R 1.724 1.00
148_T 155_P 1.707 1.00
54_I 78_L 1.703 1.00
65_T 76_I 1.69 1.00
52_L 64_L 1.68 1.00
77_I 116_L 1.657 1.00
142_L 170_V 1.65 1.00
55_N 82_R 1.636 1.00
168_A 182_L 1.595 1.00
93_E 114_K 1.581 1.00
172_N 175_E 1.56 1.00
6_V 32_T 1.558 1.00
168_A 185_M 1.555 1.00
52_L 65_T 1.549 1.00
97_D 119_R 1.543 1.00
141_C 150_E 1.543 1.00
65_T 78_L 1.54 1.00
8_V 56_L 1.528 1.00
82_R 87_D 1.526 1.00
67_A 70_E 1.506 1.00
78_L 96_A 1.472 1.00
98_D 112_R 1.461 1.00
50_I 74_V 1.438 1.00
178_S 181_R 1.436 1.00
25_E 110_V 1.414 1.00
9_E 15_Q 1.409 1.00
69_R 97_D 1.401 0.99
59_E 63_M 1.393 0.99
30_S 41_I 1.391 0.99
35_G 64_L 1.389 0.99
39_R 64_L 1.356 0.99
177_L 185_M 1.335 0.99
63_M 66_R 1.301 0.99
173_P 177_L 1.3 0.99
62_L 94_M 1.295 0.99
203_I 207_R 1.29 0.99
36_A 59_E 1.279 0.99
41_I 45_Q 1.268 0.99
40_E 44_N 1.263 0.99
143_N 146_R 1.26 0.99
41_I 44_N 1.252 0.99
218_Q 224_F 1.249 0.99
54_I 62_L 1.244 0.98
30_S 45_Q 1.219 0.98
168_A 177_L 1.219 0.98
27_Y 114_K 1.216 0.98
43_Q 71_R 1.198 0.98
147_H 164_E 1.194 0.98
36_A 40_E 1.184 0.98
26_G 114_K 1.172 0.98
42_M 68_L 1.159 0.97
32_T 38_L 1.154 0.97
147_H 221_E 1.152 0.97
39_R 59_E 1.151 0.97
84_D 87_D 1.148 0.97
66_R 90_V 1.146 0.97
116_L 119_R 1.142 0.97
144_V 167_V 1.135 0.97
201_V 204_R 1.133 0.97
37_G 40_E 1.132 0.97
12_P 33_A 1.13 0.97
49_L 117_L 1.128 0.97
55_N 81_G 1.105 0.96
198_T 202_L 1.103 0.96
134_C 141_C 1.1 0.96
10_D 53_D 1.097 0.96
180_E 196_L 1.097 0.96
18_L 79_V 1.093 0.96
175_E 181_R 1.092 0.96
150_E 155_P 1.083 0.96
5_I 27_Y 1.082 0.96
8_V 50_I 1.082 0.96
86_I 90_V 1.068 0.95
6_V 38_L 1.063 0.95
142_L 163_Y 1.058 0.95
115_N 120_I 1.044 0.94
6_V 47_V 1.042 0.94
62_L 90_V 1.042 0.94
85_R 89_I 1.028 0.94
7_I 29_V 1.026 0.94
89_I 107_R 1.025 0.93
168_A 172_N 1.024 0.93
38_L 42_M 1.023 0.93
145_S 175_E 1.022 0.93
180_E 184_R 1.022 0.93
37_G 41_I 1.013 0.93
137_F 225_L 1.004 0.93
56_L 64_L 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2gwrA10.96521000.124Contact Map0.671
1ys7A20.96961000.125Contact Map0.774
3r0jA20.97831000.125Contact Map0.68
2oqrA10.96961000.131Contact Map0.565
4b09A120.97391000.152Contact Map0.681
1kgsA10.95651000.153Contact Map0.712
1p2fA10.93041000.176Contact Map0.745
2hqrA20.92611000.184Contact Map0.683
3q9sA10.9131000.212Contact Map0.685
4hyeA20.84351000.285Contact Map0.803

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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