| UniProt: | P77634 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13629 | ||
| Length: | 265 (246) | ||
| Sequences: | 13035 | ||
| Seq/Len: | 52.99 |
| YBCM
Paralog alert: 0.81 [within 20: 0.31] - ratio of genomes with paralogs Cluster includes: ADIY APPY ARAC CHBR ENVY EUTR FEAR GADW GADX MARA MELR RHAR RHAS SOXS YBCM YDEO YDIP YEAM YIDL YIJO YKGD YPDC YQHC |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 215_L | 252_F | 3.391 | 1.00 | |
| 227_K | 235_E | 3.242 | 1.00 | |
| 170_L | 174_E | 3.2 | 1.00 | |
| 174_E | 177_T | 3.159 | 1.00 | |
| 204_V | 212_D | 3.148 | 1.00 | |
| 182_N | 192_V | 3.146 | 1.00 | |
| 172_L | 213_V | 3.094 | 1.00 | |
| 219_L | 252_F | 2.974 | 1.00 | |
| 217_N | 220_S | 2.903 | 1.00 | |
| 248_F | 259_I | 2.758 | 1.00 | |
| 212_D | 251_R | 2.415 | 1.00 | |
| 218_A | 244_F | 2.409 | 1.00 | |
| 221_A | 235_E | 2.31 | 1.00 | |
| 199_L | 209_I | 2.272 | 1.00 | |
| 171_L | 210_L | 2.25 | 1.00 | |
| 180_T | 183_K | 2.235 | 1.00 | |
| 227_K | 231_E | 2.114 | 1.00 | |
| 215_L | 251_R | 2.11 | 1.00 | |
| 221_A | 227_K | 2.074 | 1.00 | |
| 30_P | 61_C | 2.064 | 1.00 | |
| 138_L | 141_G | 2.06 | 1.00 | |
| 221_A | 236_N | 2.026 | 1.00 | |
| 31_A | 65_F | 1.997 | 1.00 | |
| 222_I | 229_I | 1.975 | 1.00 | |
| 228_P | 231_E | 1.948 | 1.00 | |
| 175_P | 213_V | 1.932 | 1.00 | |
| 170_L | 187_Y | 1.911 | 1.00 | |
| 41_V | 48_T | 1.905 | 1.00 | |
| 171_L | 213_V | 1.876 | 1.00 | |
| 217_N | 221_A | 1.859 | 1.00 | |
| 39_K | 50_T | 1.853 | 1.00 | |
| 36_R | 79_E | 1.829 | 1.00 | |
| 41_V | 50_T | 1.816 | 1.00 | |
| 190_I | 195_L | 1.773 | 1.00 | |
| 207_Q | 211_D | 1.758 | 1.00 | |
| 169_N | 173_S | 1.756 | 1.00 | |
| 254_I | 262_A | 1.754 | 1.00 | |
| 167_C | 195_L | 1.751 | 1.00 | |
| 181_A | 196_H | 1.742 | 1.00 | |
| 257_R | 261_K | 1.726 | 1.00 | |
| 219_L | 259_I | 1.724 | 1.00 | |
| 37_Q | 77_L | 1.709 | 1.00 | |
| 184_V | 206_F | 1.696 | 1.00 | |
| 52_D | 55_Q | 1.674 | 1.00 | |
| 170_L | 179_W | 1.657 | 1.00 | |
| 43_N | 48_T | 1.645 | 1.00 | |
| 230_S | 241_P | 1.638 | 1.00 | |
| 167_C | 188_L | 1.621 | 1.00 | |
| 194_T | 197_R | 1.597 | 1.00 | |
| 39_K | 52_D | 1.588 | 1.00 | |
| 192_V | 196_H | 1.581 | 1.00 | |
| 231_E | 235_E | 1.563 | 1.00 | |
| 218_A | 236_N | 1.56 | 1.00 | |
| 177_T | 183_K | 1.531 | 1.00 | |
| 194_T | 198_R | 1.521 | 1.00 | |
| 245_T | 255_T | 1.504 | 1.00 | |
| 225_T | 260_R | 1.502 | 1.00 | |
| 172_L | 209_I | 1.493 | 1.00 | |
| 205_S | 208_S | 1.489 | 1.00 | |
| 231_E | 234_R | 1.477 | 1.00 | |
| 220_S | 224_T | 1.474 | 1.00 | |
| 167_C | 184_V | 1.471 | 1.00 | |
| 254_I | 258_E | 1.464 | 1.00 | |
| 41_V | 68_E | 1.455 | 1.00 | |
| 182_N | 186_R | 1.451 | 1.00 | |
| 190_I | 194_T | 1.443 | 1.00 | |
| 243_R | 247_R | 1.434 | 1.00 | |
| 43_N | 66_Y | 1.422 | 1.00 | |
| 230_S | 234_R | 1.407 | 0.99 | |
| 45_E | 63_Y | 1.406 | 0.99 | |
| 204_V | 208_S | 1.393 | 0.99 | |
| 195_L | 206_F | 1.383 | 0.99 | |
| 241_P | 245_T | 1.382 | 0.99 | |
| 206_F | 210_L | 1.373 | 0.99 | |
| 217_N | 236_N | 1.369 | 0.99 | |
| 247_R | 250_N | 1.358 | 0.99 | |
| 245_T | 257_R | 1.353 | 0.99 | |
| 60_P | 63_Y | 1.345 | 0.99 | |
| 213_V | 217_N | 1.316 | 0.99 | |
| 168_Y | 172_L | 1.312 | 0.99 | |
| 141_G | 145_S | 1.309 | 0.99 | |
| 175_P | 217_N | 1.308 | 0.99 | |
| 184_V | 187_Y | 1.298 | 0.99 | |
| 232_I | 236_N | 1.287 | 0.99 | |
| 137_H | 144_L | 1.281 | 0.99 | |
| 117_Y | 120_E | 1.279 | 0.99 | |
| 255_T | 258_E | 1.276 | 0.99 | |
| 193_S | 197_R | 1.273 | 0.99 | |
| 242_S | 245_T | 1.249 | 0.99 | |
| 240_C | 246_E | 1.248 | 0.99 | |
| 227_K | 232_I | 1.233 | 0.98 | |
| 229_I | 232_I | 1.224 | 0.98 | |
| 37_Q | 53_N | 1.216 | 0.98 | |
| 116_I | 120_E | 1.209 | 0.98 | |
| 183_K | 187_Y | 1.208 | 0.98 | |
| 170_L | 184_V | 1.206 | 0.98 | |
| 238_Y | 247_R | 1.194 | 0.98 | |
| 181_A | 206_F | 1.177 | 0.98 | |
| 246_E | 250_N | 1.149 | 0.97 | |
| 225_T | 232_I | 1.132 | 0.97 | |
| 212_D | 216_N | 1.123 | 0.97 | |
| 191_S | 194_T | 1.115 | 0.96 | |
| 213_V | 216_N | 1.11 | 0.96 | |
| 163_L | 188_L | 1.105 | 0.96 | |
| 214_R | 236_N | 1.101 | 0.96 | |
| 29_M | 82_Y | 1.098 | 0.96 | |
| 35_I | 38_G | 1.098 | 0.96 | |
| 134_I | 138_L | 1.091 | 0.96 | |
| 245_T | 249_H | 1.09 | 0.96 | |
| 211_D | 247_R | 1.087 | 0.96 | |
| 185_A | 192_V | 1.081 | 0.95 | |
| 196_H | 206_F | 1.077 | 0.95 | |
| 36_R | 77_L | 1.041 | 0.94 | |
| 163_L | 190_I | 1.033 | 0.94 | |
| 176_G | 217_N | 1.028 | 0.94 | |
| 120_E | 124_T | 1.022 | 0.93 | |
| 252_F | 259_I | 1.019 | 0.93 | |
| 39_K | 70_Y | 1.019 | 0.93 | |
| 176_G | 235_E | 1.015 | 0.93 | |
| 183_K | 186_R | 1.008 | 0.93 | |
| 215_L | 247_R | 1.008 | 0.93 | |
| 164_I | 167_C | 1.003 | 0.93 | |
| 175_P | 210_L | 1.002 | 0.92 | |
| 51_V | 57_I | 1.002 | 0.92 | |
| 165_S | 169_N | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3gbgA | 1 | 0.9811 | 100 | 0.228 | Contact Map | 0.637 |
| 3oouA | 1 | 0.4038 | 100 | 0.46 | Contact Map | 0.773 |
| 3oioA | 1 | 0.4151 | 100 | 0.46 | Contact Map | 0.777 |
| 1bl0A | 1 | 0.4302 | 99.9 | 0.465 | Contact Map | 0.728 |
| 3mklA | 2 | 0.4151 | 99.9 | 0.466 | Contact Map | 0.802 |
| 3mn2A | 2 | 0.3962 | 99.9 | 0.468 | Contact Map | 0.751 |
| 2k9sA | 1 | 0.3962 | 99.9 | 0.472 | Contact Map | 0.556 |
| 3w6vA | 1 | 0.5283 | 99.9 | 0.476 | Contact Map | 0.773 |
| 3lsgA | 5 | 0.3811 | 99.9 | 0.481 | Contact Map | 0.871 |
| 4fe7A | 1 | 0.9019 | 99.9 | 0.484 | Contact Map | 0.776 |
Sequence Conservation (Image Generated using WebLogo v3)