| UniProt: | P77396 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG14150 | ||
| Length: | 285 (245) | ||
| Sequences: | 12234 | ||
| Seq/Len: | 49.93 |
| YPDC
Paralog alert: 0.80 [within 20: 0.21] - ratio of genomes with paralogs Cluster includes: ADIY APPY ARAC CHBR ENVY EUTR FEAR GADW GADX MARA MELR RHAR RHAS SOXS YBCM YDEO YDIP YEAM YIDL YIJO YKGD YPDC YQHC |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 235_M | 272_F | 3.383 | 1.00 | |
| 193_N | 196_Q | 3.264 | 1.00 | |
| 201_E | 211_P | 3.148 | 1.00 | |
| 189_W | 193_N | 3.119 | 1.00 | |
| 247_L | 255_R | 3.079 | 1.00 | |
| 191_Q | 233_V | 2.954 | 1.00 | |
| 224_M | 232_W | 2.947 | 1.00 | |
| 239_R | 272_F | 2.927 | 1.00 | |
| 237_K | 240_M | 2.884 | 1.00 | |
| 268_F | 279_Y | 2.744 | 1.00 | |
| 238_A | 264_F | 2.456 | 1.00 | |
| 241_I | 255_R | 2.394 | 1.00 | |
| 232_W | 271_Q | 2.376 | 1.00 | |
| 190_V | 230_V | 2.373 | 1.00 | |
| 218_F | 229_Y | 2.223 | 1.00 | |
| 199_T | 202_S | 2.187 | 1.00 | |
| 247_L | 251_E | 2.104 | 1.00 | |
| 60_G | 67_Q | 2.087 | 1.00 | |
| 156_L | 159_S | 2.08 | 1.00 | |
| 242_L | 249_I | 2.071 | 1.00 | |
| 241_I | 247_L | 2.04 | 1.00 | |
| 235_M | 271_Q | 2.02 | 1.00 | |
| 189_W | 206_F | 1.976 | 1.00 | |
| 49_P | 80_A | 1.967 | 1.00 | |
| 248_S | 251_E | 1.963 | 1.00 | |
| 241_I | 256_C | 1.947 | 1.00 | |
| 194_Y | 233_V | 1.943 | 1.00 | |
| 58_E | 69_R | 1.921 | 1.00 | |
| 60_G | 69_R | 1.916 | 1.00 | |
| 237_K | 241_I | 1.872 | 1.00 | |
| 183_Y | 222_G | 1.855 | 1.00 | |
| 186_I | 214_L | 1.837 | 1.00 | |
| 190_V | 233_V | 1.804 | 1.00 | |
| 71_V | 74_E | 1.769 | 1.00 | |
| 188_N | 192_D | 1.752 | 1.00 | |
| 58_E | 71_V | 1.728 | 1.00 | |
| 227_I | 231_R | 1.721 | 1.00 | |
| 186_I | 207_F | 1.719 | 1.00 | |
| 62_L | 67_Q | 1.715 | 1.00 | |
| 209_I | 214_L | 1.713 | 1.00 | |
| 55_L | 95_L | 1.713 | 1.00 | |
| 189_W | 198_L | 1.7 | 1.00 | |
| 56_R | 93_M | 1.691 | 1.00 | |
| 200_R | 215_S | 1.675 | 1.00 | |
| 277_G | 281_A | 1.645 | 1.00 | |
| 250_H | 261_S | 1.64 | 1.00 | |
| 203_V | 226_F | 1.635 | 1.00 | |
| 274_L | 282_R | 1.624 | 1.00 | |
| 251_E | 255_R | 1.586 | 1.00 | |
| 238_A | 256_C | 1.58 | 1.00 | |
| 187_C | 222_G | 1.571 | 1.00 | |
| 213_H | 216_K | 1.553 | 1.00 | |
| 239_R | 279_Y | 1.552 | 1.00 | |
| 191_Q | 229_Y | 1.549 | 1.00 | |
| 245_Y | 280_S | 1.53 | 1.00 | |
| 213_H | 217_L | 1.497 | 1.00 | |
| 265_C | 275_T | 1.485 | 1.00 | |
| 196_Q | 202_S | 1.476 | 1.00 | |
| 201_E | 205_Q | 1.461 | 1.00 | |
| 251_E | 254_Q | 1.444 | 1.00 | |
| 214_L | 226_F | 1.444 | 1.00 | |
| 252_V | 256_C | 1.439 | 1.00 | |
| 134_E | 138_T | 1.438 | 1.00 | |
| 274_L | 278_E | 1.434 | 1.00 | |
| 225_R | 228_E | 1.427 | 1.00 | |
| 240_M | 244_K | 1.426 | 1.00 | |
| 211_P | 215_S | 1.422 | 1.00 | |
| 64_E | 82_A | 1.421 | 1.00 | |
| 186_I | 203_V | 1.418 | 1.00 | |
| 209_I | 213_H | 1.411 | 1.00 | |
| 250_H | 254_Q | 1.404 | 0.99 | |
| 194_Y | 237_K | 1.396 | 0.99 | |
| 224_M | 228_E | 1.355 | 0.99 | |
| 189_W | 203_V | 1.345 | 0.99 | |
| 45_C | 84_N | 1.345 | 0.99 | |
| 233_V | 237_K | 1.335 | 0.99 | |
| 62_L | 85_L | 1.324 | 0.99 | |
| 267_V | 270_R | 1.31 | 0.99 | |
| 212_N | 216_K | 1.305 | 0.99 | |
| 261_S | 265_C | 1.304 | 0.99 | |
| 47_D | 84_N | 1.299 | 0.99 | |
| 265_C | 277_G | 1.298 | 0.99 | |
| 263_Y | 267_V | 1.296 | 0.99 | |
| 247_L | 252_V | 1.295 | 0.99 | |
| 237_K | 256_C | 1.29 | 0.99 | |
| 202_S | 206_F | 1.288 | 0.99 | |
| 226_F | 230_V | 1.284 | 0.99 | |
| 262_D | 265_C | 1.252 | 0.99 | |
| 182_L | 207_F | 1.239 | 0.98 | |
| 249_I | 252_V | 1.234 | 0.98 | |
| 187_C | 191_Q | 1.23 | 0.98 | |
| 56_R | 72_E | 1.221 | 0.98 | |
| 203_V | 206_F | 1.212 | 0.98 | |
| 258_F | 267_V | 1.208 | 0.98 | |
| 182_L | 209_I | 1.203 | 0.98 | |
| 260_D | 266_R | 1.203 | 0.98 | |
| 275_T | 278_E | 1.199 | 0.98 | |
| 79_P | 82_A | 1.184 | 0.98 | |
| 155_P | 162_H | 1.167 | 0.97 | |
| 60_G | 87_V | 1.163 | 0.97 | |
| 232_W | 236_A | 1.146 | 0.97 | |
| 266_R | 270_R | 1.14 | 0.97 | |
| 50_R | 84_N | 1.133 | 0.97 | |
| 44_L | 83_A | 1.118 | 0.96 | |
| 200_R | 226_F | 1.117 | 0.96 | |
| 245_Y | 252_V | 1.114 | 0.96 | |
| 55_L | 93_M | 1.104 | 0.96 | |
| 234_R | 256_C | 1.102 | 0.96 | |
| 265_C | 269_R | 1.101 | 0.96 | |
| 210_T | 213_H | 1.09 | 0.96 | |
| 135_A | 139_A | 1.088 | 0.96 | |
| 47_D | 50_R | 1.087 | 0.96 | |
| 233_V | 236_A | 1.079 | 0.95 | |
| 195_A | 237_K | 1.079 | 0.95 | |
| 54_V | 57_G | 1.06 | 0.95 | |
| 48_F | 98_V | 1.058 | 0.95 | |
| 204_A | 211_P | 1.048 | 0.94 | |
| 215_S | 226_F | 1.043 | 0.94 | |
| 54_V | 59_Y | 1.024 | 0.93 | |
| 202_S | 205_Q | 1.016 | 0.93 | |
| 180_D | 221_H | 1.016 | 0.93 | |
| 155_P | 159_S | 1.009 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3gbgA | 1 | 0.9123 | 100 | 0.291 | Contact Map | 0.647 |
| 3oouA | 1 | 0.3789 | 100 | 0.5 | Contact Map | 0.776 |
| 3oioA | 1 | 0.3895 | 100 | 0.5 | Contact Map | 0.787 |
| 1bl0A | 1 | 0.4035 | 100 | 0.505 | Contact Map | 0.739 |
| 3mn2A | 2 | 0.3719 | 100 | 0.507 | Contact Map | 0.767 |
| 3mklA | 2 | 0.386 | 100 | 0.511 | Contact Map | 0.808 |
| 2k9sA | 1 | 0.3719 | 100 | 0.511 | Contact Map | 0.549 |
| 3w6vA | 1 | 0.4842 | 100 | 0.515 | Contact Map | 0.766 |
| 3lsgA | 5 | 0.3579 | 99.9 | 0.521 | Contact Map | 0.875 |
| 4fe7A | 1 | 0.8982 | 99.9 | 0.526 | Contact Map | 0.789 |
Sequence Conservation (Image Generated using WebLogo v3)