| UniProt: | P0A9E0 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10054 | ||
| Length: | 292 (246) | ||
| Sequences: | 11517 | ||
| Seq/Len: | 46.82 |
| ARAC
Paralog alert: 0.76 [within 20: 0.19] - ratio of genomes with paralogs Cluster includes: ADIY APPY ARAC CHBR ENVY EUTR FEAR GADW GADX MARA MELR RHAR RHAS SOXS YBCM YDEO YDIP YEAM YIDL YIJO YKGD YPDC YQHC |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 232_I | 269_T | 3.455 | 1.00 | |
| 189_H | 192_D | 3.249 | 1.00 | |
| 244_M | 252_N | 3.088 | 1.00 | |
| 198_A | 208_P | 3.056 | 1.00 | |
| 185_Y | 189_H | 3.054 | 1.00 | |
| 221_I | 229_D | 3.003 | 1.00 | |
| 234_Q | 237_L | 2.873 | 1.00 | |
| 236_K | 269_T | 2.847 | 1.00 | |
| 265_F | 276_F | 2.83 | 1.00 | |
| 187_S | 230_Q | 2.724 | 1.00 | |
| 235_A | 261_F | 2.407 | 1.00 | |
| 238_L | 252_N | 2.357 | 1.00 | |
| 229_D | 268_C | 2.349 | 1.00 | |
| 186_I | 227_R | 2.318 | 1.00 | |
| 196_D | 199_S | 2.18 | 1.00 | |
| 215_F | 226_W | 2.152 | 1.00 | |
| 56_V | 63_E | 2.068 | 1.00 | |
| 238_L | 244_M | 2.049 | 1.00 | |
| 244_M | 248_T | 2.017 | 1.00 | |
| 239_L | 246_I | 2.006 | 1.00 | |
| 45_Y | 76_P | 2.003 | 1.00 | |
| 232_I | 268_C | 1.962 | 1.00 | |
| 54_Q | 65_V | 1.891 | 1.00 | |
| 245_P | 248_T | 1.878 | 1.00 | |
| 56_V | 65_V | 1.874 | 1.00 | |
| 182_A | 211_L | 1.869 | 1.00 | |
| 234_Q | 238_L | 1.868 | 1.00 | |
| 238_L | 253_V | 1.847 | 1.00 | |
| 186_I | 230_Q | 1.842 | 1.00 | |
| 190_L | 230_Q | 1.821 | 1.00 | |
| 206_L | 211_L | 1.82 | 1.00 | |
| 179_V | 219_L | 1.787 | 1.00 | |
| 52_R | 92_Y | 1.783 | 1.00 | |
| 184_Q | 188_D | 1.768 | 1.00 | |
| 155_L | 158_Q | 1.767 | 1.00 | |
| 185_Y | 203_H | 1.764 | 1.00 | |
| 271_A | 279_G | 1.751 | 1.00 | |
| 54_Q | 67_R | 1.75 | 1.00 | |
| 67_R | 70_D | 1.749 | 1.00 | |
| 224_L | 228_E | 1.707 | 1.00 | |
| 58_K | 63_E | 1.706 | 1.00 | |
| 185_Y | 195_F | 1.69 | 1.00 | |
| 182_A | 204_V | 1.629 | 1.00 | |
| 197_I | 212_S | 1.628 | 1.00 | |
| 274_S | 278_A | 1.619 | 1.00 | |
| 187_S | 226_W | 1.615 | 1.00 | |
| 200_V | 223_V | 1.601 | 1.00 | |
| 51_I | 94_Q | 1.593 | 1.00 | |
| 248_T | 252_N | 1.584 | 1.00 | |
| 236_K | 276_F | 1.575 | 1.00 | |
| 210_R | 214_L | 1.567 | 1.00 | |
| 247_A | 258_Q | 1.561 | 1.00 | |
| 235_A | 253_V | 1.537 | 1.00 | |
| 242_T | 277_R | 1.522 | 1.00 | |
| 183_C | 219_L | 1.514 | 1.00 | |
| 190_L | 234_Q | 1.485 | 1.00 | |
| 46_I | 80_H | 1.466 | 1.00 | |
| 262_S | 272_S | 1.462 | 1.00 | |
| 198_A | 202_Q | 1.458 | 1.00 | |
| 247_A | 251_R | 1.44 | 1.00 | |
| 211_L | 223_V | 1.439 | 1.00 | |
| 131_S | 135_G | 1.427 | 1.00 | |
| 60_Q | 78_E | 1.423 | 1.00 | |
| 248_T | 251_R | 1.418 | 1.00 | |
| 222_S | 225_S | 1.411 | 1.00 | |
| 192_D | 199_S | 1.404 | 0.99 | |
| 249_V | 253_V | 1.402 | 0.99 | |
| 206_L | 210_R | 1.4 | 0.99 | |
| 58_K | 81_H | 1.399 | 0.99 | |
| 210_R | 213_H | 1.397 | 0.99 | |
| 208_P | 212_S | 1.393 | 0.99 | |
| 237_L | 241_T | 1.387 | 0.99 | |
| 271_A | 275_E | 1.378 | 0.99 | |
| 56_V | 83_G | 1.369 | 0.99 | |
| 154_N | 158_Q | 1.361 | 0.99 | |
| 154_N | 161_L | 1.359 | 0.99 | |
| 42_M | 80_H | 1.352 | 0.99 | |
| 221_I | 225_S | 1.346 | 0.99 | |
| 262_S | 274_S | 1.33 | 0.99 | |
| 230_Q | 234_Q | 1.329 | 0.99 | |
| 182_A | 200_V | 1.329 | 0.99 | |
| 223_V | 227_R | 1.321 | 0.99 | |
| 264_V | 267_K | 1.313 | 0.99 | |
| 199_S | 203_H | 1.309 | 0.99 | |
| 258_Q | 262_S | 1.304 | 0.99 | |
| 260_Y | 264_V | 1.29 | 0.99 | |
| 259_L | 262_S | 1.276 | 0.99 | |
| 185_Y | 200_V | 1.269 | 0.99 | |
| 40_L | 80_H | 1.268 | 0.99 | |
| 52_R | 68_P | 1.262 | 0.99 | |
| 272_S | 275_E | 1.254 | 0.99 | |
| 244_M | 249_V | 1.254 | 0.99 | |
| 151_L | 158_Q | 1.248 | 0.99 | |
| 75_P | 78_E | 1.231 | 0.98 | |
| 209_S | 213_H | 1.23 | 0.98 | |
| 234_Q | 253_V | 1.222 | 0.98 | |
| 178_R | 204_V | 1.202 | 0.98 | |
| 200_V | 203_H | 1.193 | 0.98 | |
| 140_A | 165_E | 1.189 | 0.98 | |
| 242_T | 249_V | 1.188 | 0.98 | |
| 257_D | 263_R | 1.188 | 0.98 | |
| 178_R | 206_L | 1.181 | 0.98 | |
| 144_E | 148_S | 1.156 | 0.97 | |
| 246_I | 249_V | 1.154 | 0.97 | |
| 255_F | 264_V | 1.142 | 0.97 | |
| 50_T | 53_G | 1.134 | 0.97 | |
| 197_I | 223_V | 1.131 | 0.97 | |
| 158_Q | 162_R | 1.11 | 0.96 | |
| 183_C | 187_S | 1.105 | 0.96 | |
| 263_R | 267_K | 1.095 | 0.96 | |
| 154_N | 157_E | 1.094 | 0.96 | |
| 199_S | 202_Q | 1.093 | 0.96 | |
| 212_S | 223_V | 1.047 | 0.94 | |
| 39_P | 79_I | 1.047 | 0.94 | |
| 204_V | 211_L | 1.045 | 0.94 | |
| 229_D | 233_S | 1.04 | 0.94 | |
| 201_A | 208_P | 1.037 | 0.94 | |
| 55_G | 66_C | 1.033 | 0.94 | |
| 207_S | 210_R | 1.027 | 0.94 | |
| 42_M | 46_I | 1.018 | 0.93 | |
| 269_T | 276_F | 1.017 | 0.93 | |
| 176_D | 218_Q | 1.011 | 0.93 | |
| 132_D | 136_Q | 1.003 | 0.93 | |
| 231_R | 253_V | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3gbgA | 1 | 0.9075 | 100 | 0.313 | Contact Map | 0.648 |
| 3oouA | 1 | 0.3699 | 100 | 0.53 | Contact Map | 0.782 |
| 3mn2A | 2 | 0.363 | 100 | 0.534 | Contact Map | 0.763 |
| 1bl0A | 1 | 0.4281 | 100 | 0.536 | Contact Map | 0.734 |
| 3oioA | 1 | 0.387 | 100 | 0.536 | Contact Map | 0.799 |
| 2k9sA | 1 | 0.3664 | 100 | 0.54 | Contact Map | 0.551 |
| 3mklA | 2 | 0.4041 | 100 | 0.544 | Contact Map | 0.804 |
| 3lsgA | 5 | 0.3527 | 99.9 | 0.547 | Contact Map | 0.878 |
| 3w6vA | 1 | 0.4829 | 99.9 | 0.548 | Contact Map | 0.767 |
| 1d5yA | 4 | 0.4007 | 99.9 | 0.556 | Contact Map | 0.693 |
Sequence Conservation (Image Generated using WebLogo v3)