| UniProt: | P31449 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11707 | ||
| Length: | 297 (244) | ||
| Sequences: | 6132 | ||
| Seq/Len: | 25.13 |
| YIDL
Paralog alert: 0.72 [within 20: 0.11] - ratio of genomes with paralogs Cluster includes: ADIY APPY ARAC CHBR ENVY EUTR FEAR GADW GADX MARA MELR RHAR RHAS SOXS YBCM YDEO YDIP YEAM YIDL YIJO YKGD YPDC YQHC |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 238_L | 275_F | 4.016 | 1.00 | |
| 196_S | 199_Q | 3.33 | 1.00 | |
| 242_L | 275_F | 3.069 | 1.00 | |
| 194_H | 236_A | 3.055 | 1.00 | |
| 192_T | 196_S | 2.902 | 1.00 | |
| 227_K | 235_D | 2.805 | 1.00 | |
| 250_N | 258_T | 2.801 | 1.00 | |
| 240_L | 243_S | 2.757 | 1.00 | |
| 241_A | 267_F | 2.749 | 1.00 | |
| 193_L | 233_Y | 2.738 | 1.00 | |
| 204_A | 214_E | 2.66 | 1.00 | |
| 271_F | 282_V | 2.472 | 1.00 | |
| 221_F | 232_Y | 2.445 | 1.00 | |
| 235_D | 274_K | 2.429 | 1.00 | |
| 245_L | 252_V | 2.236 | 1.00 | |
| 73_K | 81_Q | 2.226 | 1.00 | |
| 192_T | 201_W | 2.111 | 1.00 | |
| 71_C | 83_T | 2.065 | 1.00 | |
| 244_L | 258_T | 2.011 | 1.00 | |
| 244_L | 259_L | 2.004 | 1.00 | |
| 193_L | 236_A | 1.975 | 1.00 | |
| 238_L | 274_K | 1.942 | 1.00 | |
| 244_L | 250_N | 1.931 | 1.00 | |
| 63_V | 98_H | 1.923 | 1.00 | |
| 280_S | 284_K | 1.92 | 1.00 | |
| 186_I | 225_T | 1.919 | 1.00 | |
| 189_L | 217_L | 1.918 | 1.00 | |
| 212_C | 217_L | 1.913 | 1.00 | |
| 68_V | 110_Y | 1.911 | 1.00 | |
| 191_A | 195_A | 1.891 | 1.00 | |
| 69_Q | 108_E | 1.851 | 1.00 | |
| 197_L | 236_A | 1.843 | 1.00 | |
| 62_W | 94_P | 1.838 | 1.00 | |
| 194_H | 232_Y | 1.838 | 1.00 | |
| 250_N | 254_E | 1.833 | 1.00 | |
| 75_L | 81_Q | 1.809 | 1.00 | |
| 73_K | 83_T | 1.804 | 1.00 | |
| 277_Y | 285_N | 1.771 | 1.00 | |
| 161_F | 164_K | 1.769 | 1.00 | |
| 189_L | 210_I | 1.755 | 1.00 | |
| 230_K | 234_L | 1.734 | 1.00 | |
| 71_C | 85_H | 1.686 | 1.00 | |
| 206_M | 229_P | 1.683 | 1.00 | |
| 203_V | 218_R | 1.674 | 1.00 | |
| 202_S | 205_D | 1.655 | 1.00 | |
| 248_Q | 283_L | 1.654 | 1.00 | |
| 241_A | 259_L | 1.654 | 1.00 | |
| 199_Q | 205_D | 1.652 | 1.00 | |
| 251_S | 254_E | 1.646 | 1.00 | |
| 85_H | 88_C | 1.62 | 1.00 | |
| 268_S | 278_A | 1.607 | 1.00 | |
| 59_A | 98_H | 1.6 | 1.00 | |
| 73_K | 101_H | 1.596 | 1.00 | |
| 192_T | 209_T | 1.572 | 1.00 | |
| 206_M | 209_T | 1.568 | 1.00 | |
| 242_L | 282_V | 1.565 | 1.00 | |
| 204_A | 208_A | 1.561 | 1.00 | |
| 216_W | 219_R | 1.545 | 1.00 | |
| 190_I | 225_T | 1.542 | 1.00 | |
| 240_L | 244_L | 1.533 | 1.00 | |
| 217_L | 229_P | 1.513 | 1.00 | |
| 78_N | 96_D | 1.493 | 1.00 | |
| 265_F | 268_S | 1.482 | 1.00 | |
| 75_L | 99_S | 1.472 | 1.00 | |
| 229_P | 233_Y | 1.471 | 1.00 | |
| 212_C | 216_W | 1.458 | 1.00 | |
| 189_L | 206_M | 1.457 | 1.00 | |
| 197_L | 240_L | 1.457 | 1.00 | |
| 185_Q | 210_I | 1.424 | 1.00 | |
| 214_E | 218_R | 1.4 | 0.99 | |
| 266_H | 270_A | 1.394 | 0.99 | |
| 69_Q | 86_G | 1.391 | 0.99 | |
| 248_Q | 255_V | 1.343 | 0.99 | |
| 277_Y | 281_A | 1.327 | 0.99 | |
| 185_Q | 212_C | 1.326 | 0.99 | |
| 205_D | 209_T | 1.324 | 0.99 | |
| 216_W | 220_L | 1.314 | 0.99 | |
| 253_G | 264_S | 1.309 | 0.99 | |
| 255_V | 283_L | 1.305 | 0.99 | |
| 228_T | 231_E | 1.303 | 0.99 | |
| 227_K | 231_E | 1.296 | 0.99 | |
| 137_N | 141_T | 1.276 | 0.99 | |
| 268_S | 280_S | 1.273 | 0.99 | |
| 250_N | 255_V | 1.273 | 0.99 | |
| 237_R | 259_L | 1.223 | 0.98 | |
| 210_I | 217_L | 1.223 | 0.98 | |
| 254_E | 258_T | 1.215 | 0.98 | |
| 201_W | 206_M | 1.206 | 0.98 | |
| 245_L | 283_L | 1.204 | 0.98 | |
| 93_K | 96_D | 1.197 | 0.98 | |
| 263_D | 269_K | 1.192 | 0.98 | |
| 243_S | 247_Q | 1.187 | 0.98 | |
| 218_R | 228_T | 1.186 | 0.98 | |
| 57_L | 98_H | 1.186 | 0.98 | |
| 150_P | 154_K | 1.183 | 0.98 | |
| 264_S | 268_S | 1.183 | 0.98 | |
| 72_G | 107_W | 1.166 | 0.97 | |
| 203_V | 229_P | 1.15 | 0.97 | |
| 164_K | 168_Q | 1.148 | 0.97 | |
| 238_L | 270_A | 1.148 | 0.97 | |
| 261_F | 270_A | 1.139 | 0.97 | |
| 252_V | 255_V | 1.129 | 0.97 | |
| 205_D | 208_A | 1.114 | 0.96 | |
| 215_A | 219_R | 1.111 | 0.96 | |
| 236_A | 239_D | 1.107 | 0.96 | |
| 64_A | 91_F | 1.104 | 0.96 | |
| 213_S | 216_W | 1.099 | 0.96 | |
| 238_L | 261_F | 1.096 | 0.96 | |
| 278_A | 281_A | 1.087 | 0.96 | |
| 269_K | 273_H | 1.083 | 0.96 | |
| 270_A | 273_H | 1.081 | 0.95 | |
| 88_C | 132_N | 1.08 | 0.95 | |
| 67_T | 70_G | 1.079 | 0.95 | |
| 253_G | 257_D | 1.07 | 0.95 | |
| 67_T | 72_G | 1.069 | 0.95 | |
| 192_T | 206_M | 1.069 | 0.95 | |
| 197_L | 233_Y | 1.058 | 0.95 | |
| 59_A | 63_V | 1.049 | 0.94 | |
| 218_R | 229_P | 1.047 | 0.94 | |
| 236_A | 240_L | 1.047 | 0.94 | |
| 198_Q | 258_T | 1.042 | 0.94 | |
| 255_V | 259_L | 1.037 | 0.94 | |
| 75_L | 101_H | 1.036 | 0.94 | |
| 240_L | 259_L | 1.036 | 0.94 | |
| 254_E | 257_D | 1.03 | 0.94 | |
| 189_L | 209_T | 1.029 | 0.94 | |
| 242_L | 271_F | 1.018 | 0.93 | |
| 189_L | 192_T | 1.006 | 0.93 | |
| 268_S | 272_K | 1.005 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3gbgA | 1 | 0.8519 | 100 | 0.333 | Contact Map | 0.641 |
| 3oouA | 1 | 0.3636 | 100 | 0.524 | Contact Map | 0.78 |
| 1bl0A | 1 | 0.4175 | 100 | 0.526 | Contact Map | 0.727 |
| 3mn2A | 2 | 0.3569 | 100 | 0.526 | Contact Map | 0.758 |
| 3oioA | 1 | 0.3805 | 100 | 0.529 | Contact Map | 0.787 |
| 2k9sA | 1 | 0.3569 | 100 | 0.532 | Contact Map | 0.536 |
| 3mklA | 2 | 0.4007 | 100 | 0.538 | Contact Map | 0.796 |
| 3lsgA | 5 | 0.3434 | 100 | 0.539 | Contact Map | 0.863 |
| 3w6vA | 1 | 0.4848 | 100 | 0.541 | Contact Map | 0.763 |
| 1d5yA | 4 | 0.3906 | 99.9 | 0.547 | Contact Map | 0.707 |
Sequence Conservation (Image Generated using WebLogo v3)