| UniProt: | P09378 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10842 | ||
| Length: | 282 (252) | ||
| Sequences: | 12795 | ||
| Seq/Len: | 50.77 |
| RHAR
Paralog alert: 0.80 [within 20: 0.29] - ratio of genomes with paralogs Cluster includes: ADIY APPY ARAC CHBR ENVY EUTR FEAR GADW GADX MARA MELR RHAR RHAS SOXS YBCM YDEO YDIP YEAM YIDL YIJO YKGD YPDC YQHC |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 230_V | 267_T | 3.405 | 1.00 | |
| 188_S | 191_S | 3.214 | 1.00 | |
| 184_R | 188_S | 3.151 | 1.00 | |
| 242_L | 250_E | 3.145 | 1.00 | |
| 196_D | 206_E | 3.095 | 1.00 | |
| 219_M | 227_Q | 3.029 | 1.00 | |
| 186_A | 228_V | 2.99 | 1.00 | |
| 232_H | 235_Y | 2.952 | 1.00 | |
| 234_Q | 267_T | 2.937 | 1.00 | |
| 263_F | 274_W | 2.809 | 1.00 | |
| 233_A | 259_F | 2.449 | 1.00 | |
| 236_L | 250_E | 2.387 | 1.00 | |
| 185_L | 225_L | 2.381 | 1.00 | |
| 227_Q | 266_E | 2.348 | 1.00 | |
| 194_A | 197_K | 2.217 | 1.00 | |
| 213_F | 224_Y | 2.173 | 1.00 | |
| 50_L | 57_P | 2.071 | 1.00 | |
| 242_L | 246_D | 2.051 | 1.00 | |
| 236_L | 242_L | 2.034 | 1.00 | |
| 230_V | 266_E | 2.033 | 1.00 | |
| 237_L | 244_I | 2.004 | 1.00 | |
| 184_R | 201_E | 1.975 | 1.00 | |
| 39_C | 70_A | 1.966 | 1.00 | |
| 243_L | 246_D | 1.951 | 1.00 | |
| 236_L | 251_C | 1.945 | 1.00 | |
| 189_L | 228_V | 1.925 | 1.00 | |
| 50_L | 59_R | 1.914 | 1.00 | |
| 232_H | 236_L | 1.897 | 1.00 | |
| 48_N | 59_R | 1.895 | 1.00 | |
| 178_L | 217_T | 1.878 | 1.00 | |
| 185_L | 228_V | 1.854 | 1.00 | |
| 151_L | 154_Q | 1.845 | 1.00 | |
| 181_L | 209_L | 1.809 | 1.00 | |
| 204_C | 209_L | 1.756 | 1.00 | |
| 46_R | 83_V | 1.742 | 1.00 | |
| 184_R | 193_F | 1.72 | 1.00 | |
| 181_L | 202_A | 1.713 | 1.00 | |
| 48_N | 61_T | 1.711 | 1.00 | |
| 272_S | 276_H | 1.7 | 1.00 | |
| 61_T | 64_D | 1.693 | 1.00 | |
| 269_M | 277_L | 1.686 | 1.00 | |
| 52_V | 57_P | 1.682 | 1.00 | |
| 222_N | 226_R | 1.675 | 1.00 | |
| 195_L | 210_R | 1.673 | 1.00 | |
| 245_S | 256_S | 1.657 | 1.00 | |
| 183_T | 187_A | 1.653 | 1.00 | |
| 234_Q | 274_W | 1.649 | 1.00 | |
| 45_W | 85_Q | 1.634 | 1.00 | |
| 198_F | 221_I | 1.614 | 1.00 | |
| 246_D | 250_E | 1.601 | 1.00 | |
| 186_A | 224_Y | 1.567 | 1.00 | |
| 208_V | 212_Q | 1.553 | 1.00 | |
| 208_V | 211_Q | 1.539 | 1.00 | |
| 240_S | 275_R | 1.537 | 1.00 | |
| 260_S | 270_T | 1.523 | 1.00 | |
| 233_A | 251_C | 1.513 | 1.00 | |
| 182_I | 217_T | 1.503 | 1.00 | |
| 136_E | 161_R | 1.494 | 1.00 | |
| 246_D | 249_T | 1.485 | 1.00 | |
| 191_S | 197_K | 1.47 | 1.00 | |
| 196_D | 200_D | 1.45 | 1.00 | |
| 269_M | 273_Q | 1.449 | 1.00 | |
| 127_R | 131_G | 1.447 | 1.00 | |
| 52_V | 75_S | 1.423 | 1.00 | |
| 206_E | 210_R | 1.421 | 1.00 | |
| 235_Y | 239_H | 1.42 | 1.00 | |
| 245_S | 249_T | 1.42 | 1.00 | |
| 69_H | 72_D | 1.418 | 1.00 | |
| 204_C | 208_V | 1.417 | 1.00 | |
| 220_T | 223_Q | 1.416 | 1.00 | |
| 36_H | 74_H | 1.399 | 0.99 | |
| 181_L | 198_F | 1.382 | 0.99 | |
| 189_L | 232_H | 1.365 | 0.99 | |
| 150_L | 157_M | 1.363 | 0.99 | |
| 221_I | 225_L | 1.334 | 0.99 | |
| 260_S | 272_S | 1.33 | 0.99 | |
| 219_M | 223_Q | 1.326 | 0.99 | |
| 256_S | 260_S | 1.324 | 0.99 | |
| 54_N | 72_D | 1.323 | 0.99 | |
| 232_H | 251_C | 1.322 | 0.99 | |
| 247_I | 251_C | 1.32 | 0.99 | |
| 209_L | 221_I | 1.306 | 0.99 | |
| 258_Y | 262_V | 1.306 | 0.99 | |
| 50_L | 77_A | 1.3 | 0.99 | |
| 262_V | 265_R | 1.299 | 0.99 | |
| 184_R | 198_F | 1.299 | 0.99 | |
| 207_R | 211_Q | 1.286 | 0.99 | |
| 240_S | 247_I | 1.265 | 0.99 | |
| 64_D | 117_R | 1.263 | 0.99 | |
| 270_T | 273_Q | 1.261 | 0.99 | |
| 197_K | 201_E | 1.251 | 0.99 | |
| 147_M | 154_Q | 1.247 | 0.99 | |
| 182_I | 186_A | 1.244 | 0.98 | |
| 40_E | 74_H | 1.239 | 0.98 | |
| 34_H | 74_H | 1.234 | 0.98 | |
| 253_F | 262_V | 1.234 | 0.98 | |
| 228_V | 232_H | 1.222 | 0.98 | |
| 257_N | 260_S | 1.215 | 0.98 | |
| 244_I | 247_I | 1.214 | 0.98 | |
| 128_Q | 132_Q | 1.199 | 0.98 | |
| 255_D | 261_V | 1.197 | 0.98 | |
| 46_R | 62_R | 1.196 | 0.98 | |
| 177_L | 202_A | 1.19 | 0.98 | |
| 198_F | 201_E | 1.188 | 0.98 | |
| 242_L | 247_I | 1.179 | 0.98 | |
| 140_H | 144_A | 1.156 | 0.97 | |
| 195_L | 221_I | 1.156 | 0.97 | |
| 227_Q | 231_C | 1.145 | 0.97 | |
| 228_V | 231_C | 1.138 | 0.97 | |
| 210_R | 221_I | 1.137 | 0.97 | |
| 261_V | 265_R | 1.133 | 0.97 | |
| 205_S | 208_V | 1.133 | 0.97 | |
| 177_L | 204_C | 1.129 | 0.97 | |
| 260_S | 264_T | 1.082 | 0.96 | |
| 199_C | 206_E | 1.066 | 0.95 | |
| 44_V | 47_G | 1.063 | 0.95 | |
| 267_T | 274_W | 1.062 | 0.95 | |
| 229_R | 251_C | 1.06 | 0.95 | |
| 190_K | 232_H | 1.057 | 0.95 | |
| 33_E | 73_K | 1.057 | 0.95 | |
| 36_H | 40_E | 1.056 | 0.95 | |
| 255_D | 258_Y | 1.038 | 0.94 | |
| 150_L | 153_G | 1.034 | 0.94 | |
| 128_Q | 131_G | 1.029 | 0.94 | |
| 45_W | 83_V | 1.028 | 0.94 | |
| 175_E | 216_Q | 1.027 | 0.94 | |
| 247_I | 275_R | 1.023 | 0.93 | |
| 193_F | 198_F | 1.014 | 0.93 | |
| 44_V | 49_G | 1.004 | 0.93 | |
| 60_I | 66_F | 1.002 | 0.92 | |
| 49_G | 60_I | 1.001 | 0.92 | |
| 197_K | 200_D | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3gbgA | 1 | 0.9326 | 100 | 0.24 | Contact Map | 0.651 |
| 3oioA | 1 | 0.4007 | 100 | 0.479 | Contact Map | 0.793 |
| 3oouA | 1 | 0.383 | 100 | 0.479 | Contact Map | 0.783 |
| 1bl0A | 1 | 0.4149 | 100 | 0.484 | Contact Map | 0.735 |
| 3mn2A | 2 | 0.3759 | 99.9 | 0.487 | Contact Map | 0.759 |
| 3w6vA | 1 | 0.5106 | 99.9 | 0.489 | Contact Map | 0.76 |
| 2k9sA | 1 | 0.3759 | 99.9 | 0.492 | Contact Map | 0.548 |
| 3mklA | 2 | 0.3972 | 99.9 | 0.496 | Contact Map | 0.801 |
| 3lsgA | 5 | 0.3617 | 99.9 | 0.5 | Contact Map | 0.88 |
| 1d5yA | 4 | 0.3865 | 99.9 | 0.506 | Contact Map | 0.697 |
Sequence Conservation (Image Generated using WebLogo v3)