| UniProt: | P77379 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13581 | ||
| Length: | 284 (255) | ||
| Sequences: | 11594 | ||
| Seq/Len: | 45.47 |
| YKGD
Paralog alert: 0.78 [within 20: 0.19] - ratio of genomes with paralogs Cluster includes: ADIY APPY ARAC CHBR ENVY EUTR FEAR GADW GADX MARA MELR RHAR RHAS SOXS YBCM YDEO YDIP YEAM YIDL YIJO YKGD YPDC YQHC |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 231_L | 268_F | 3.709 | 1.00 | |
| 189_M | 192_H | 3.277 | 1.00 | |
| 243_L | 251_S | 3.252 | 1.00 | |
| 197_E | 207_R | 3.182 | 1.00 | |
| 185_Q | 189_M | 3.174 | 1.00 | |
| 220_T | 228_K | 3.105 | 1.00 | |
| 187_L | 229_L | 3.017 | 1.00 | |
| 235_A | 268_F | 2.932 | 1.00 | |
| 264_F | 275_Y | 2.883 | 1.00 | |
| 233_I | 236_Q | 2.851 | 1.00 | |
| 234_A | 260_F | 2.545 | 1.00 | |
| 237_M | 251_S | 2.462 | 1.00 | |
| 228_K | 267_E | 2.46 | 1.00 | |
| 186_M | 226_L | 2.419 | 1.00 | |
| 195_T | 198_S | 2.289 | 1.00 | |
| 214_F | 225_V | 2.244 | 1.00 | |
| 237_M | 243_L | 2.053 | 1.00 | |
| 50_K | 58_I | 2.05 | 1.00 | |
| 238_F | 245_V | 2.04 | 1.00 | |
| 243_L | 247_V | 2.036 | 1.00 | |
| 244_P | 247_V | 1.999 | 1.00 | |
| 231_L | 267_E | 1.998 | 1.00 | |
| 50_K | 60_T | 1.947 | 1.00 | |
| 237_M | 252_V | 1.939 | 1.00 | |
| 48_A | 60_T | 1.924 | 1.00 | |
| 182_V | 210_F | 1.905 | 1.00 | |
| 147_Q | 154_T | 1.902 | 1.00 | |
| 233_I | 237_M | 1.896 | 1.00 | |
| 185_Q | 202_I | 1.884 | 1.00 | |
| 190_P | 229_L | 1.868 | 1.00 | |
| 40_R | 75_H | 1.868 | 1.00 | |
| 186_M | 229_L | 1.862 | 1.00 | |
| 270_C | 278_R | 1.816 | 1.00 | |
| 62_R | 65_N | 1.809 | 1.00 | |
| 184_Q | 188_E | 1.796 | 1.00 | |
| 205_M | 210_F | 1.79 | 1.00 | |
| 39_I | 71_Q | 1.786 | 1.00 | |
| 223_L | 227_T | 1.771 | 1.00 | |
| 179_L | 218_S | 1.767 | 1.00 | |
| 273_G | 277_E | 1.722 | 1.00 | |
| 52_E | 58_I | 1.719 | 1.00 | |
| 196_V | 211_A | 1.683 | 1.00 | |
| 48_A | 62_R | 1.672 | 1.00 | |
| 182_V | 203_A | 1.663 | 1.00 | |
| 185_Q | 194_W | 1.651 | 1.00 | |
| 246_V | 257_E | 1.632 | 1.00 | |
| 209_S | 213_L | 1.624 | 1.00 | |
| 199_L | 222_P | 1.614 | 1.00 | |
| 247_V | 251_S | 1.61 | 1.00 | |
| 187_L | 225_V | 1.596 | 1.00 | |
| 234_A | 252_V | 1.592 | 1.00 | |
| 235_A | 275_Y | 1.579 | 1.00 | |
| 241_E | 276_R | 1.578 | 1.00 | |
| 148_I | 151_T | 1.544 | 1.00 | |
| 133_E | 158_R | 1.542 | 1.00 | |
| 192_H | 198_S | 1.534 | 1.00 | |
| 124_R | 128_P | 1.523 | 1.00 | |
| 50_K | 78_S | 1.51 | 1.00 | |
| 52_E | 76_R | 1.504 | 1.00 | |
| 183_I | 218_S | 1.494 | 1.00 | |
| 46_Q | 86_C | 1.492 | 1.00 | |
| 197_E | 201_S | 1.491 | 1.00 | |
| 261_H | 273_G | 1.48 | 1.00 | |
| 54_P | 73_S | 1.472 | 1.00 | |
| 209_S | 212_Q | 1.471 | 1.00 | |
| 270_C | 274_E | 1.461 | 1.00 | |
| 182_V | 199_L | 1.456 | 1.00 | |
| 205_M | 209_S | 1.449 | 1.00 | |
| 236_Q | 240_R | 1.444 | 1.00 | |
| 247_V | 250_E | 1.434 | 1.00 | |
| 207_R | 211_A | 1.43 | 1.00 | |
| 259_S | 263_A | 1.428 | 1.00 | |
| 246_V | 250_E | 1.415 | 1.00 | |
| 261_H | 271_T | 1.41 | 1.00 | |
| 221_T | 224_A | 1.398 | 0.99 | |
| 190_P | 233_I | 1.396 | 0.99 | |
| 147_Q | 150_A | 1.392 | 0.99 | |
| 248_I | 252_V | 1.39 | 0.99 | |
| 222_P | 226_L | 1.355 | 0.99 | |
| 257_E | 261_H | 1.348 | 0.99 | |
| 185_Q | 199_L | 1.341 | 0.99 | |
| 220_T | 224_A | 1.34 | 0.99 | |
| 198_S | 202_I | 1.339 | 0.99 | |
| 210_F | 222_P | 1.335 | 0.99 | |
| 229_L | 233_I | 1.332 | 0.99 | |
| 70_P | 73_S | 1.329 | 0.99 | |
| 208_A | 212_Q | 1.315 | 0.99 | |
| 258_S | 261_H | 1.295 | 0.99 | |
| 233_I | 252_V | 1.291 | 0.99 | |
| 243_L | 248_I | 1.287 | 0.99 | |
| 271_T | 274_E | 1.279 | 0.99 | |
| 263_A | 266_R | 1.278 | 0.99 | |
| 46_Q | 63_P | 1.275 | 0.99 | |
| 154_T | 158_R | 1.271 | 0.99 | |
| 254_Y | 263_A | 1.231 | 0.98 | |
| 178_R | 205_M | 1.225 | 0.98 | |
| 245_V | 248_I | 1.222 | 0.98 | |
| 241_E | 248_I | 1.217 | 0.98 | |
| 147_Q | 151_T | 1.212 | 0.98 | |
| 230_R | 252_V | 1.198 | 0.98 | |
| 45_T | 88_V | 1.185 | 0.98 | |
| 125_E | 128_P | 1.179 | 0.98 | |
| 199_L | 202_I | 1.17 | 0.97 | |
| 196_V | 222_P | 1.169 | 0.97 | |
| 206_S | 209_S | 1.161 | 0.97 | |
| 137_A | 141_V | 1.142 | 0.97 | |
| 183_I | 187_L | 1.142 | 0.97 | |
| 262_K | 266_R | 1.131 | 0.97 | |
| 44_L | 49_A | 1.127 | 0.97 | |
| 178_R | 203_A | 1.122 | 0.97 | |
| 211_A | 222_P | 1.121 | 0.97 | |
| 268_F | 275_Y | 1.115 | 0.96 | |
| 198_S | 201_S | 1.114 | 0.96 | |
| 256_S | 262_K | 1.113 | 0.96 | |
| 200_A | 207_R | 1.111 | 0.96 | |
| 229_L | 232_Q | 1.101 | 0.96 | |
| 49_A | 61_L | 1.071 | 0.95 | |
| 61_L | 67_V | 1.066 | 0.95 | |
| 261_H | 265_V | 1.05 | 0.94 | |
| 194_W | 199_L | 1.047 | 0.94 | |
| 52_E | 78_S | 1.045 | 0.94 | |
| 176_H | 217_V | 1.027 | 0.94 | |
| 228_K | 232_Q | 1.025 | 0.93 | |
| 182_V | 202_I | 1.017 | 0.93 | |
| 248_I | 276_R | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3gbgA | 1 | 0.9225 | 100 | 0.249 | Contact Map | 0.647 |
| 3oouA | 1 | 0.3803 | 100 | 0.469 | Contact Map | 0.782 |
| 3oioA | 1 | 0.3979 | 100 | 0.47 | Contact Map | 0.789 |
| 3mn2A | 2 | 0.3732 | 100 | 0.472 | Contact Map | 0.766 |
| 1bl0A | 1 | 0.4155 | 100 | 0.474 | Contact Map | 0.728 |
| 3w6vA | 1 | 0.5106 | 99.9 | 0.48 | Contact Map | 0.767 |
| 2k9sA | 1 | 0.3732 | 99.9 | 0.481 | Contact Map | 0.553 |
| 3mklA | 2 | 0.3979 | 99.9 | 0.484 | Contact Map | 0.805 |
| 3lsgA | 5 | 0.3592 | 99.9 | 0.488 | Contact Map | 0.876 |
| 1d5yA | 4 | 0.3873 | 99.9 | 0.494 | Contact Map | 0.686 |
Sequence Conservation (Image Generated using WebLogo v3)