| UniProt: | P39831 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12345 | ||
| Length: | 248 (231) | ||
| Sequences: | 52561 | ||
| Seq/Len: | 227.54 |
| YDFG
Paralog alert: 0.88 [within 20: 0.48] - ratio of genomes with paralogs Cluster includes: BDCA ENTA FABG FABI FOLM HCAB HDHA IDNO KDUD SRLD UCPA YBBO YCIK YDFG YGCW YGFF YGHA YOHF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 100_E | 108_K | 3.215 | 1.00 | |
| 100_E | 104_D | 2.933 | 1.00 | |
| 152_A | 156_Q | 2.846 | 1.00 | |
| 57_N | 60_A | 2.729 | 1.00 | |
| 131_N | 158_S | 2.667 | 1.00 | |
| 128_H | 171_R | 2.481 | 1.00 | |
| 69_P | 120_G | 2.373 | 1.00 | |
| 3_V | 77_I | 2.366 | 1.00 | |
| 14_E | 18_R | 2.294 | 1.00 | |
| 133_G | 155_R | 2.253 | 1.00 | |
| 114_T | 161_L | 2.232 | 1.00 | |
| 62_E | 116_A | 2.229 | 1.00 | |
| 122_V | 168_T | 2.182 | 1.00 | |
| 34_Q | 38_Q | 2.177 | 1.00 | |
| 80_N | 131_N | 2.131 | 1.00 | |
| 19_R | 214_E | 2.121 | 1.00 | |
| 182_G | 208_T | 2.064 | 1.00 | |
| 104_D | 108_K | 1.995 | 1.00 | |
| 118_L | 165_L | 1.982 | 1.00 | |
| 77_I | 220_S | 1.963 | 1.00 | |
| 65_L | 117_V | 1.96 | 1.00 | |
| 26_K | 47_N | 1.914 | 1.00 | |
| 19_R | 217_W | 1.885 | 1.00 | |
| 19_R | 23_Q | 1.883 | 1.00 | |
| 58_R | 96_V | 1.882 | 1.00 | |
| 2_I | 26_K | 1.866 | 1.00 | |
| 30_T | 53_L | 1.834 | 1.00 | |
| 12_F | 180_V | 1.784 | 1.00 | |
| 110_L | 154_V | 1.765 | 1.00 | |
| 106_N | 150_T | 1.736 | 1.00 | |
| 16_I | 216_V | 1.724 | 1.00 | |
| 158_S | 174_D | 1.695 | 1.00 | |
| 25_H | 77_I | 1.688 | 1.00 | |
| 18_R | 43_E | 1.686 | 1.00 | |
| 8_A | 29_A | 1.678 | 1.00 | |
| 67_S | 71_E | 1.673 | 1.00 | |
| 14_E | 40_L | 1.647 | 1.00 | |
| 9_T | 31_G | 1.644 | 1.00 | |
| 33_R | 36_R | 1.619 | 1.00 | |
| 28_I | 72_W | 1.606 | 1.00 | |
| 128_H | 173_T | 1.59 | 1.00 | |
| 107_N | 153_F | 1.585 | 1.00 | |
| 23_Q | 217_W | 1.576 | 1.00 | |
| 14_E | 43_E | 1.574 | 1.00 | |
| 49_Y | 71_E | 1.559 | 1.00 | |
| 28_I | 68_L | 1.557 | 1.00 | |
| 20_F | 220_S | 1.551 | 1.00 | |
| 37_L | 50_I | 1.549 | 1.00 | |
| 66_A | 70_A | 1.538 | 1.00 | |
| 103_I | 107_N | 1.514 | 1.00 | |
| 30_T | 64_M | 1.506 | 1.00 | |
| 19_R | 22_Q | 1.503 | 1.00 | |
| 79_V | 132_I | 1.5 | 1.00 | |
| 2_I | 74_N | 1.493 | 1.00 | |
| 63_E | 67_S | 1.476 | 1.00 | |
| 53_L | 60_A | 1.471 | 1.00 | |
| 96_V | 112_Y | 1.44 | 1.00 | |
| 3_V | 20_F | 1.44 | 1.00 | |
| 34_Q | 52_Q | 1.429 | 1.00 | |
| 95_S | 98_D | 1.429 | 1.00 | |
| 78_L | 113_M | 1.419 | 1.00 | |
| 62_E | 66_A | 1.415 | 1.00 | |
| 10_A | 184_E | 1.397 | 0.99 | |
| 67_S | 70_A | 1.394 | 0.99 | |
| 58_R | 112_Y | 1.355 | 0.99 | |
| 38_Q | 42_D | 1.352 | 0.99 | |
| 61_I | 113_M | 1.349 | 0.99 | |
| 58_R | 62_E | 1.318 | 0.99 | |
| 53_L | 64_M | 1.316 | 0.99 | |
| 51_A | 67_S | 1.304 | 0.99 | |
| 15_C | 210_E | 1.302 | 0.99 | |
| 80_N | 114_T | 1.292 | 0.99 | |
| 3_V | 25_H | 1.29 | 0.99 | |
| 133_G | 174_D | 1.289 | 0.99 | |
| 60_A | 63_E | 1.287 | 0.99 | |
| 108_K | 112_Y | 1.276 | 0.99 | |
| 15_C | 18_R | 1.275 | 0.99 | |
| 20_F | 25_H | 1.269 | 0.99 | |
| 17_T | 29_A | 1.262 | 0.99 | |
| 120_G | 124_R | 1.252 | 0.99 | |
| 114_T | 129_I | 1.249 | 0.99 | |
| 41_K | 50_I | 1.221 | 0.98 | |
| 2_I | 28_I | 1.216 | 0.98 | |
| 158_S | 172_V | 1.213 | 0.98 | |
| 175_I | 216_V | 1.209 | 0.98 | |
| 75_I | 117_V | 1.187 | 0.98 | |
| 19_R | 213_S | 1.179 | 0.98 | |
| 161_L | 172_V | 1.163 | 0.97 | |
| 10_A | 36_R | 1.157 | 0.97 | |
| 78_L | 117_V | 1.151 | 0.97 | |
| 103_I | 108_K | 1.134 | 0.97 | |
| 26_K | 46_D | 1.132 | 0.97 | |
| 18_R | 22_Q | 1.131 | 0.97 | |
| 92_H | 122_V | 1.131 | 0.97 | |
| 74_N | 124_R | 1.112 | 0.96 | |
| 59_A | 63_E | 1.111 | 0.96 | |
| 49_Y | 72_W | 1.108 | 0.96 | |
| 96_V | 108_K | 1.098 | 0.96 | |
| 97_E | 101_T | 1.096 | 0.96 | |
| 81_N | 132_I | 1.095 | 0.96 | |
| 38_Q | 41_K | 1.094 | 0.96 | |
| 147_Y | 151_K | 1.088 | 0.96 | |
| 16_I | 213_S | 1.088 | 0.96 | |
| 51_A | 64_M | 1.086 | 0.96 | |
| 111_V | 157_F | 1.085 | 0.96 | |
| 173_T | 219_V | 1.082 | 0.96 | |
| 84_L | 105_T | 1.081 | 0.95 | |
| 63_E | 66_A | 1.079 | 0.95 | |
| 26_K | 49_Y | 1.071 | 0.95 | |
| 138_S | 176_E | 1.064 | 0.95 | |
| 56_R | 101_T | 1.056 | 0.95 | |
| 4_L | 64_M | 1.045 | 0.94 | |
| 132_I | 216_V | 1.042 | 0.94 | |
| 20_F | 217_W | 1.039 | 0.94 | |
| 90_P | 93_K | 1.029 | 0.94 | |
| 89_E | 98_D | 1.027 | 0.94 | |
| 110_L | 131_N | 1.023 | 0.93 | |
| 19_R | 210_E | 1.021 | 0.93 | |
| 15_C | 209_P | 1.016 | 0.93 | |
| 12_F | 16_I | 1.014 | 0.93 | |
| 114_T | 157_F | 1.008 | 0.93 | |
| 29_A | 48_L | 1.005 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2et6A | 1 | 0.9516 | 100 | 0.127 | Contact Map | 0.732 |
| 3asuA | 2 | 0.996 | 100 | 0.136 | Contact Map | 0.833 |
| 3op4A | 2 | 0.9597 | 100 | 0.145 | Contact Map | 0.743 |
| 2c07A | 1 | 0.9556 | 100 | 0.146 | Contact Map | 0.769 |
| 2nwqA | 4 | 0.996 | 100 | 0.146 | Contact Map | 0.834 |
| 1vl8A | 2 | 0.9597 | 100 | 0.149 | Contact Map | 0.798 |
| 4fn4A | 4 | 0.9637 | 100 | 0.151 | Contact Map | 0.923 |
| 3grpA | 4 | 0.9597 | 100 | 0.152 | Contact Map | 0.865 |
| 1zemA | 8 | 0.9476 | 100 | 0.153 | Contact Map | 0.848 |
| 3v8bA | 4 | 0.9677 | 100 | 0.155 | Contact Map | 0.834 |
Sequence Conservation (Image Generated using WebLogo v3)