| UniProt: | P05707 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10971 | ||
| Length: | 259 (251) | ||
| Sequences: | 47348 | ||
| Seq/Len: | 188.64 |
| SRLD
Paralog alert: 0.89 [within 20: 0.47] - ratio of genomes with paralogs Cluster includes: BDCA ENTA FABG FABI FOLM HCAB HDHA IDNO KDUD SRLD UCPA YBBO YCIK YDFG YGCW YGFF YGHA YOHF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 106_D | 114_V | 3.262 | 1.00 | |
| 106_D | 110_Q | 2.91 | 1.00 | |
| 64_S | 67_S | 2.781 | 1.00 | |
| 159_F | 163_G | 2.758 | 1.00 | |
| 138_Q | 165_T | 2.584 | 1.00 | |
| 135_R | 178_T | 2.549 | 1.00 | |
| 16_A | 20_H | 2.343 | 1.00 | |
| 5_A | 84_L | 2.339 | 1.00 | |
| 76_D | 126_L | 2.322 | 1.00 | |
| 120_A | 168_L | 2.233 | 1.00 | |
| 183_M | 249_S | 2.226 | 1.00 | |
| 36_S | 40_A | 2.203 | 1.00 | |
| 140_N | 162_V | 2.19 | 1.00 | |
| 69_L | 122_E | 2.182 | 1.00 | |
| 128_I | 175_Y | 2.163 | 1.00 | |
| 189_K | 226_D | 2.148 | 1.00 | |
| 84_L | 238_A | 2.097 | 1.00 | |
| 87_Y | 138_Q | 2.055 | 1.00 | |
| 21_G | 232_N | 2.015 | 1.00 | |
| 72_S | 123_F | 1.956 | 1.00 | |
| 28_R | 54_M | 1.915 | 1.00 | |
| 65_E | 102_L | 1.906 | 1.00 | |
| 124_S | 172_L | 1.905 | 1.00 | |
| 110_Q | 114_V | 1.9 | 1.00 | |
| 21_G | 235_L | 1.876 | 1.00 | |
| 232_N | 241_K | 1.851 | 1.00 | |
| 21_G | 25_E | 1.829 | 1.00 | |
| 4_V | 28_R | 1.826 | 1.00 | |
| 32_V | 60_A | 1.818 | 1.00 | |
| 18_L | 234_L | 1.817 | 1.00 | |
| 248_Q | 251_N | 1.803 | 1.00 | |
| 116_Y | 161_G | 1.778 | 1.00 | |
| 2_N | 27_Y | 1.776 | 1.00 | |
| 112_N | 157_A | 1.774 | 1.00 | |
| 14_L | 188_L | 1.759 | 1.00 | |
| 20_H | 45_E | 1.737 | 1.00 | |
| 233_M | 250_I | 1.709 | 1.00 | |
| 165_T | 181_S | 1.7 | 1.00 | |
| 11_G | 33_D | 1.65 | 1.00 | |
| 74_G | 78_I | 1.648 | 1.00 | |
| 22_L | 238_A | 1.64 | 1.00 | |
| 10_G | 31_V | 1.62 | 1.00 | |
| 73_R | 77_E | 1.618 | 1.00 | |
| 16_A | 42_V | 1.615 | 1.00 | |
| 27_Y | 84_L | 1.601 | 1.00 | |
| 25_E | 235_L | 1.599 | 1.00 | |
| 16_A | 45_E | 1.584 | 1.00 | |
| 109_L | 113_L | 1.58 | 1.00 | |
| 30_A | 75_V | 1.572 | 1.00 | |
| 39_A | 57_G | 1.567 | 1.00 | |
| 113_L | 160_G | 1.56 | 1.00 | |
| 32_V | 71_L | 1.548 | 1.00 | |
| 30_A | 79_F | 1.541 | 1.00 | |
| 35_Q | 38_K | 1.499 | 1.00 | |
| 56_Y | 78_I | 1.498 | 1.00 | |
| 70_A | 74_G | 1.491 | 1.00 | |
| 182_L | 234_L | 1.491 | 1.00 | |
| 69_L | 73_R | 1.483 | 1.00 | |
| 101_Q | 104_D | 1.483 | 1.00 | |
| 60_A | 67_S | 1.477 | 1.00 | |
| 4_V | 81_R | 1.468 | 1.00 | |
| 85_L | 119_C | 1.457 | 1.00 | |
| 21_G | 24_A | 1.455 | 1.00 | |
| 225_C | 244_Y | 1.448 | 1.00 | |
| 102_L | 118_L | 1.433 | 1.00 | |
| 5_A | 22_L | 1.426 | 1.00 | |
| 40_A | 44_Q | 1.414 | 1.00 | |
| 74_G | 77_E | 1.404 | 0.99 | |
| 86_V | 139_I | 1.401 | 0.99 | |
| 12_Q | 191_P | 1.371 | 0.99 | |
| 135_R | 180_H | 1.366 | 0.99 | |
| 188_L | 225_C | 1.349 | 0.99 | |
| 68_V | 119_C | 1.338 | 0.99 | |
| 36_S | 59_G | 1.328 | 0.99 | |
| 65_E | 118_L | 1.327 | 0.99 | |
| 19_C | 31_V | 1.308 | 0.99 | |
| 60_A | 71_L | 1.303 | 0.99 | |
| 87_Y | 120_A | 1.264 | 0.99 | |
| 67_S | 70_A | 1.264 | 0.99 | |
| 65_E | 69_L | 1.256 | 0.99 | |
| 233_M | 252_V | 1.253 | 0.99 | |
| 140_N | 181_S | 1.245 | 0.98 | |
| 126_L | 130_D | 1.242 | 0.98 | |
| 114_V | 118_L | 1.239 | 0.98 | |
| 22_L | 27_Y | 1.235 | 0.98 | |
| 82_V | 123_F | 1.234 | 0.98 | |
| 28_R | 52_E | 1.231 | 0.98 | |
| 58_F | 74_G | 1.223 | 0.98 | |
| 168_L | 179_V | 1.223 | 0.98 | |
| 5_A | 27_Y | 1.205 | 0.98 | |
| 102_L | 114_V | 1.194 | 0.98 | |
| 17_F | 228_Q | 1.19 | 0.98 | |
| 120_A | 136_I | 1.185 | 0.98 | |
| 56_Y | 79_F | 1.153 | 0.97 | |
| 20_H | 24_A | 1.152 | 0.97 | |
| 165_T | 179_V | 1.149 | 0.97 | |
| 43_A | 57_G | 1.147 | 0.97 | |
| 17_F | 20_H | 1.145 | 0.97 | |
| 98_S | 128_I | 1.142 | 0.97 | |
| 66_Q | 70_A | 1.138 | 0.97 | |
| 21_G | 231_L | 1.129 | 0.97 | |
| 85_L | 123_F | 1.129 | 0.97 | |
| 93_K | 107_R | 1.123 | 0.97 | |
| 145_K | 251_N | 1.115 | 0.96 | |
| 4_V | 30_A | 1.11 | 0.96 | |
| 81_R | 130_D | 1.098 | 0.96 | |
| 109_L | 114_V | 1.096 | 0.96 | |
| 181_S | 249_S | 1.089 | 0.96 | |
| 91_I | 111_V | 1.081 | 0.95 | |
| 70_A | 73_R | 1.079 | 0.95 | |
| 236_F | 245_C | 1.078 | 0.95 | |
| 95_A | 104_D | 1.075 | 0.95 | |
| 139_I | 234_L | 1.067 | 0.95 | |
| 18_L | 86_V | 1.063 | 0.95 | |
| 105_F | 114_V | 1.062 | 0.95 | |
| 40_A | 43_A | 1.056 | 0.95 | |
| 117_F | 164_L | 1.055 | 0.95 | |
| 103_G | 107_R | 1.053 | 0.95 | |
| 88_S | 139_I | 1.049 | 0.94 | |
| 162_V | 249_S | 1.046 | 0.94 | |
| 31_V | 55_A | 1.042 | 0.94 | |
| 6_V | 71_L | 1.038 | 0.94 | |
| 154_Y | 158_K | 1.033 | 0.94 | |
| 44_Q | 48_A | 1.026 | 0.94 | |
| 58_F | 71_L | 1.023 | 0.93 | |
| 12_Q | 38_K | 1.021 | 0.93 | |
| 96_F | 99_D | 1.01 | 0.93 | |
| 223_R | 229_D | 1.002 | 0.92 | |
| 63_T | 107_R | 1 | 0.92 | |
| 14_L | 18_L | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1vl8A | 2 | 0.9537 | 100 | 0.054 | Contact Map | 0.805 |
| 2c07A | 1 | 0.9382 | 100 | 0.058 | Contact Map | 0.754 |
| 3sjuA | 2 | 0.9846 | 100 | 0.061 | Contact Map | 0.759 |
| 2z1nA | 2 | 0.9807 | 100 | 0.061 | Contact Map | 0.793 |
| 2rhcB | 2 | 0.9846 | 100 | 0.062 | Contact Map | 0.817 |
| 1zemA | 8 | 0.9691 | 100 | 0.064 | Contact Map | 0.861 |
| 4j2hA | 1 | 0.9498 | 100 | 0.064 | Contact Map | 0.742 |
| 1gegA | 8 | 0.9884 | 100 | 0.065 | Contact Map | 0.893 |
| 4fc7A | 4 | 0.9575 | 100 | 0.065 | Contact Map | 0.882 |
| 4iboA | 4 | 0.9498 | 100 | 0.066 | Contact Map | 0.843 |
Sequence Conservation (Image Generated using WebLogo v3)