| UniProt: | P76633 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13130 | ||
| Length: | 261 (247) | ||
| Sequences: | 49431 | ||
| Seq/Len: | 200.13 |
| YGCW
Paralog alert: 0.89 [within 20: 0.47] - ratio of genomes with paralogs Cluster includes: BDCA ENTA FABG FABI FOLM HCAB HDHA IDNO KDUD SRLD UCPA YBBO YCIK YDFG YGCW YGFF YGHA YOHF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 119_D | 127_T | 3.212 | 1.00 | |
| 119_D | 123_D | 2.872 | 1.00 | |
| 77_A | 80_A | 2.802 | 1.00 | |
| 171_H | 175_G | 2.699 | 1.00 | |
| 150_N | 177_T | 2.55 | 1.00 | |
| 147_K | 190_Q | 2.42 | 1.00 | |
| 32_Q | 36_M | 2.321 | 1.00 | |
| 89_C | 139_I | 2.32 | 1.00 | |
| 21_A | 97_I | 2.29 | 1.00 | |
| 133_S | 180_Y | 2.19 | 1.00 | |
| 152_C | 174_A | 2.185 | 1.00 | |
| 195_A | 251_L | 2.174 | 1.00 | |
| 82_Q | 135_E | 2.174 | 1.00 | |
| 200_A | 228_D | 2.143 | 1.00 | |
| 141_I | 187_Y | 2.139 | 1.00 | |
| 52_K | 55_G | 2.137 | 1.00 | |
| 100_N | 150_N | 2.058 | 1.00 | |
| 37_A | 234_G | 2.028 | 1.00 | |
| 97_I | 240_A | 2.028 | 1.00 | |
| 44_N | 67_E | 1.931 | 1.00 | |
| 85_I | 136_A | 1.92 | 1.00 | |
| 123_D | 127_T | 1.917 | 1.00 | |
| 78_E | 115_R | 1.906 | 1.00 | |
| 137_A | 184_L | 1.888 | 1.00 | |
| 37_A | 237_V | 1.847 | 1.00 | |
| 234_G | 243_A | 1.832 | 1.00 | |
| 48_P | 73_V | 1.831 | 1.00 | |
| 37_A | 41_A | 1.826 | 1.00 | |
| 20_T | 44_N | 1.807 | 1.00 | |
| 30_L | 199_Y | 1.77 | 1.00 | |
| 250_H | 253_V | 1.769 | 1.00 | |
| 129_A | 173_L | 1.767 | 1.00 | |
| 34_F | 236_A | 1.756 | 1.00 | |
| 125_N | 169_T | 1.755 | 1.00 | |
| 36_M | 60_M | 1.748 | 1.00 | |
| 32_Q | 57_T | 1.68 | 1.00 | |
| 235_A | 252_L | 1.675 | 1.00 | |
| 177_T | 193_G | 1.67 | 1.00 | |
| 87_A | 91_R | 1.663 | 1.00 | |
| 32_Q | 60_M | 1.648 | 1.00 | |
| 27_N | 49_S | 1.638 | 1.00 | |
| 26_G | 47_I | 1.627 | 1.00 | |
| 38_L | 240_A | 1.602 | 1.00 | |
| 86_A | 90_E | 1.596 | 1.00 | |
| 54_N | 70_F | 1.588 | 1.00 | |
| 46_F | 92_F | 1.549 | 1.00 | |
| 46_F | 88_C | 1.545 | 1.00 | |
| 41_A | 237_V | 1.543 | 1.00 | |
| 126_L | 172_A | 1.541 | 1.00 | |
| 122_I | 126_L | 1.535 | 1.00 | |
| 69_D | 91_R | 1.527 | 1.00 | |
| 48_P | 84_I | 1.515 | 1.00 | |
| 83_K | 87_A | 1.494 | 1.00 | |
| 37_A | 40_K | 1.472 | 1.00 | |
| 43_A | 97_I | 1.471 | 1.00 | |
| 114_G | 117_D | 1.467 | 1.00 | |
| 82_Q | 86_A | 1.459 | 1.00 | |
| 73_V | 80_A | 1.453 | 1.00 | |
| 20_T | 94_T | 1.448 | 1.00 | |
| 227_G | 246_Y | 1.433 | 1.00 | |
| 99_V | 151_I | 1.423 | 1.00 | |
| 147_K | 192_N | 1.422 | 1.00 | |
| 98_L | 132_L | 1.419 | 1.00 | |
| 55_G | 59_E | 1.414 | 1.00 | |
| 21_A | 38_L | 1.413 | 1.00 | |
| 87_A | 90_E | 1.41 | 1.00 | |
| 115_R | 131_E | 1.394 | 0.99 | |
| 52_K | 72_Q | 1.371 | 0.99 | |
| 194_I | 236_A | 1.356 | 0.99 | |
| 28_S | 202_D | 1.337 | 0.99 | |
| 18_G | 43_A | 1.333 | 0.99 | |
| 81_P | 132_L | 1.332 | 0.99 | |
| 73_V | 84_I | 1.311 | 0.99 | |
| 78_E | 131_E | 1.293 | 0.99 | |
| 35_A | 47_I | 1.275 | 0.99 | |
| 58_K | 62_E | 1.271 | 0.99 | |
| 100_N | 133_S | 1.265 | 0.99 | |
| 71_M | 87_A | 1.262 | 0.99 | |
| 80_A | 83_K | 1.252 | 0.99 | |
| 44_N | 66_V | 1.249 | 0.99 | |
| 199_Y | 227_G | 1.247 | 0.99 | |
| 78_E | 82_Q | 1.246 | 0.98 | |
| 139_I | 143_Q | 1.241 | 0.98 | |
| 127_T | 131_E | 1.234 | 0.98 | |
| 235_A | 254_V | 1.227 | 0.98 | |
| 16_L | 43_A | 1.224 | 0.98 | |
| 21_A | 43_A | 1.222 | 0.98 | |
| 152_C | 193_G | 1.222 | 0.98 | |
| 58_K | 70_F | 1.207 | 0.98 | |
| 133_S | 148_I | 1.204 | 0.98 | |
| 38_L | 43_A | 1.197 | 0.98 | |
| 95_V | 136_A | 1.191 | 0.98 | |
| 33_A | 230_Q | 1.191 | 0.98 | |
| 177_T | 191_V | 1.184 | 0.98 | |
| 33_A | 36_M | 1.182 | 0.98 | |
| 180_Y | 191_V | 1.179 | 0.98 | |
| 115_R | 127_T | 1.156 | 0.97 | |
| 79_G | 83_K | 1.149 | 0.97 | |
| 36_M | 40_K | 1.147 | 0.97 | |
| 59_E | 63_K | 1.146 | 0.97 | |
| 37_A | 233_M | 1.14 | 0.97 | |
| 69_D | 92_F | 1.14 | 0.97 | |
| 59_E | 62_E | 1.137 | 0.97 | |
| 20_T | 46_F | 1.131 | 0.97 | |
| 111_L | 141_I | 1.128 | 0.97 | |
| 122_I | 127_T | 1.102 | 0.96 | |
| 104_I | 124_V | 1.1 | 0.96 | |
| 98_L | 136_A | 1.099 | 0.96 | |
| 106_K | 120_P | 1.093 | 0.96 | |
| 157_Y | 253_V | 1.091 | 0.96 | |
| 22_I | 84_I | 1.083 | 0.96 | |
| 116_A | 120_P | 1.083 | 0.96 | |
| 94_T | 143_Q | 1.078 | 0.95 | |
| 83_K | 86_A | 1.077 | 0.95 | |
| 193_G | 251_L | 1.067 | 0.95 | |
| 71_M | 84_I | 1.061 | 0.95 | |
| 108_N | 117_D | 1.06 | 0.95 | |
| 40_K | 64_Q | 1.057 | 0.95 | |
| 118_W | 127_T | 1.056 | 0.95 | |
| 151_I | 236_A | 1.052 | 0.95 | |
| 130_F | 176_F | 1.048 | 0.94 | |
| 55_G | 58_K | 1.041 | 0.94 | |
| 109_K | 112_D | 1.032 | 0.94 | |
| 76_T | 120_P | 1.029 | 0.94 | |
| 238_F | 247_V | 1.029 | 0.94 | |
| 34_F | 99_V | 1.021 | 0.93 | |
| 166_Y | 170_K | 1.018 | 0.93 | |
| 101_N | 151_I | 1.017 | 0.93 | |
| 174_A | 251_L | 1.017 | 0.93 | |
| 33_A | 229_T | 1.017 | 0.93 | |
| 38_L | 237_V | 1.01 | 0.93 | |
| 47_I | 68_V | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3cxtA | 1 | 1 | 100 | 0.131 | Contact Map | 0.697 |
| 4g81D | 4 | 0.9655 | 100 | 0.139 | Contact Map | 0.808 |
| 4j2hA | 1 | 0.977 | 100 | 0.141 | Contact Map | 0.748 |
| 4iboA | 4 | 1 | 100 | 0.142 | Contact Map | 0.837 |
| 2et6A | 1 | 0.9004 | 100 | 0.142 | Contact Map | 0.723 |
| 2zatA | 4 | 0.9847 | 100 | 0.144 | Contact Map | 0.852 |
| 3lf2A | 4 | 0.9617 | 100 | 0.145 | Contact Map | 0.837 |
| 4egfA | 8 | 0.9923 | 100 | 0.145 | Contact Map | 0.825 |
| 3v8bA | 4 | 1 | 100 | 0.146 | Contact Map | 0.832 |
| 1vl8A | 2 | 0.9962 | 100 | 0.146 | Contact Map | 0.798 |
Sequence Conservation (Image Generated using WebLogo v3)