| UniProt: | P52037 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12971 | ||
| Length: | 247 (241) | ||
| Sequences: | 54563 | ||
| Seq/Len: | 226.40 |
| YGFF
Paralog alert: 0.88 [within 20: 0.49] - ratio of genomes with paralogs Cluster includes: BDCA ENTA FABG FABI FOLM HCAB HDHA IDNO KDUD SRLD UCPA YBBO YCIK YDFG YGCW YGFF YGHA YOHF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 105_N | 113_T | 3.225 | 1.00 | |
| 105_N | 109_S | 2.882 | 1.00 | |
| 161_G | 165_T | 2.832 | 1.00 | |
| 62_D | 65_Q | 2.671 | 1.00 | |
| 139_N | 167_T | 2.593 | 1.00 | |
| 136_A | 180_R | 2.329 | 1.00 | |
| 4_A | 82_A | 2.298 | 1.00 | |
| 15_R | 19_L | 2.254 | 1.00 | |
| 67_V | 121_E | 2.252 | 1.00 | |
| 119_C | 170_L | 2.214 | 1.00 | |
| 36_L | 40_Q | 2.196 | 1.00 | |
| 127_A | 177_Q | 2.182 | 1.00 | |
| 141_S | 164_D | 2.176 | 1.00 | |
| 185_R | 240_F | 2.151 | 1.00 | |
| 190_Y | 217_Q | 2.132 | 1.00 | |
| 20_L | 223_Q | 2.084 | 1.00 | |
| 109_S | 113_T | 2.056 | 1.00 | |
| 85_N | 139_N | 1.99 | 1.00 | |
| 123_V | 174_V | 1.966 | 1.00 | |
| 82_A | 229_L | 1.956 | 1.00 | |
| 63_E | 101_A | 1.935 | 1.00 | |
| 20_L | 226_V | 1.893 | 1.00 | |
| 27_T | 52_K | 1.882 | 1.00 | |
| 70_F | 122_A | 1.874 | 1.00 | |
| 31_N | 58_A | 1.854 | 1.00 | |
| 239_S | 242_D | 1.834 | 1.00 | |
| 20_L | 24_E | 1.831 | 1.00 | |
| 3_I | 27_T | 1.816 | 1.00 | |
| 13_I | 189_I | 1.76 | 1.00 | |
| 223_Q | 232_K | 1.739 | 1.00 | |
| 111_N | 159_S | 1.735 | 1.00 | |
| 19_L | 45_L | 1.731 | 1.00 | |
| 115_Y | 163_I | 1.693 | 1.00 | |
| 167_T | 183_C | 1.68 | 1.00 | |
| 17_T | 225_I | 1.667 | 1.00 | |
| 15_R | 42_V | 1.657 | 1.00 | |
| 26_Y | 82_A | 1.637 | 1.00 | |
| 15_R | 45_L | 1.634 | 1.00 | |
| 35_N | 38_A | 1.626 | 1.00 | |
| 9_G | 30_V | 1.619 | 1.00 | |
| 224_A | 241_I | 1.603 | 1.00 | |
| 21_L | 229_L | 1.582 | 1.00 | |
| 24_E | 226_V | 1.558 | 1.00 | |
| 39_A | 55_V | 1.554 | 1.00 | |
| 31_N | 69_M | 1.541 | 1.00 | |
| 112_V | 162_A | 1.532 | 1.00 | |
| 108_L | 112_V | 1.527 | 1.00 | |
| 10_S | 32_Y | 1.526 | 1.00 | |
| 58_A | 65_Q | 1.492 | 1.00 | |
| 216_G | 235_Y | 1.485 | 1.00 | |
| 20_L | 23_Q | 1.473 | 1.00 | |
| 136_A | 182_N | 1.471 | 1.00 | |
| 101_A | 117_L | 1.47 | 1.00 | |
| 3_I | 79_P | 1.457 | 1.00 | |
| 84_V | 140_V | 1.454 | 1.00 | |
| 36_L | 57_Q | 1.426 | 1.00 | |
| 100_T | 103_R | 1.42 | 1.00 | |
| 83_L | 118_C | 1.403 | 0.99 | |
| 63_E | 117_L | 1.38 | 0.99 | |
| 11_R | 192_E | 1.378 | 0.99 | |
| 4_A | 21_L | 1.377 | 0.99 | |
| 67_V | 71_T | 1.369 | 0.99 | |
| 66_V | 118_C | 1.365 | 0.99 | |
| 43_M | 47_T | 1.355 | 0.99 | |
| 85_N | 119_C | 1.325 | 0.99 | |
| 4_A | 26_Y | 1.324 | 0.99 | |
| 40_Q | 44_N | 1.304 | 0.99 | |
| 58_A | 69_M | 1.301 | 0.99 | |
| 65_Q | 68_A | 1.3 | 0.99 | |
| 63_E | 67_V | 1.296 | 0.99 | |
| 113_T | 117_L | 1.289 | 0.99 | |
| 141_S | 183_C | 1.287 | 0.99 | |
| 71_T | 74_D | 1.283 | 0.99 | |
| 16_A | 19_L | 1.282 | 0.99 | |
| 3_I | 29_A | 1.277 | 0.99 | |
| 167_T | 181_V | 1.274 | 0.99 | |
| 16_A | 219_E | 1.26 | 0.99 | |
| 43_M | 55_V | 1.259 | 0.99 | |
| 119_C | 137_I | 1.258 | 0.99 | |
| 184_V | 225_I | 1.242 | 0.98 | |
| 224_A | 243_L | 1.233 | 0.98 | |
| 21_L | 26_Y | 1.223 | 0.98 | |
| 73_I | 125_R | 1.217 | 0.98 | |
| 108_L | 113_T | 1.199 | 0.98 | |
| 27_T | 51_G | 1.191 | 0.98 | |
| 18_A | 30_V | 1.184 | 0.98 | |
| 125_R | 129_K | 1.183 | 0.98 | |
| 189_I | 216_G | 1.176 | 0.98 | |
| 146_R | 242_D | 1.163 | 0.97 | |
| 27_T | 54_F | 1.154 | 0.97 | |
| 56_L | 69_M | 1.152 | 0.97 | |
| 97_E | 127_A | 1.151 | 0.97 | |
| 11_R | 38_A | 1.15 | 0.97 | |
| 83_L | 122_A | 1.146 | 0.97 | |
| 72_A | 76_H | 1.145 | 0.97 | |
| 20_L | 222_A | 1.144 | 0.97 | |
| 19_L | 23_Q | 1.131 | 0.97 | |
| 170_L | 181_V | 1.13 | 0.97 | |
| 80_L | 122_A | 1.125 | 0.97 | |
| 54_F | 76_H | 1.117 | 0.96 | |
| 44_N | 48_Q | 1.113 | 0.96 | |
| 102_E | 106_R | 1.108 | 0.96 | |
| 64_N | 68_A | 1.107 | 0.96 | |
| 86_N | 140_V | 1.095 | 0.96 | |
| 116_F | 166_L | 1.095 | 0.96 | |
| 23_Q | 49_A | 1.092 | 0.96 | |
| 101_A | 113_T | 1.088 | 0.96 | |
| 40_Q | 43_M | 1.085 | 0.96 | |
| 61_S | 106_R | 1.078 | 0.95 | |
| 29_A | 76_H | 1.077 | 0.95 | |
| 89_I | 110_T | 1.076 | 0.95 | |
| 44_N | 47_T | 1.067 | 0.95 | |
| 104_I | 113_T | 1.058 | 0.95 | |
| 164_D | 240_F | 1.057 | 0.95 | |
| 79_P | 129_K | 1.045 | 0.94 | |
| 95_T | 98_N | 1.045 | 0.94 | |
| 156_Y | 160_K | 1.041 | 0.94 | |
| 94_C | 103_R | 1.038 | 0.94 | |
| 16_A | 218_A | 1.033 | 0.94 | |
| 5_L | 69_M | 1.033 | 0.94 | |
| 183_C | 240_F | 1.029 | 0.94 | |
| 119_C | 166_L | 1.027 | 0.94 | |
| 54_F | 75_Q | 1.019 | 0.93 | |
| 140_V | 225_I | 1.018 | 0.93 | |
| 21_L | 226_V | 1.017 | 0.93 | |
| 146_R | 185_R | 1.013 | 0.93 | |
| 115_Y | 139_N | 1.011 | 0.93 | |
| 17_T | 222_A | 1.007 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1zemA | 8 | 0.9757 | 100 | 0.044 | Contact Map | 0.84 |
| 1vl8A | 2 | 0.9757 | 100 | 0.047 | Contact Map | 0.79 |
| 2c07A | 1 | 0.9514 | 100 | 0.048 | Contact Map | 0.737 |
| 4j2hA | 1 | 0.9757 | 100 | 0.051 | Contact Map | 0.733 |
| 3v8bA | 4 | 0.9798 | 100 | 0.053 | Contact Map | 0.834 |
| 3cxtA | 1 | 0.9555 | 100 | 0.053 | Contact Map | 0.678 |
| 4iboA | 4 | 0.9757 | 100 | 0.055 | Contact Map | 0.834 |
| 4bnwA | 4 | 0.9595 | 100 | 0.055 | Contact Map | 0.77 |
| 4ag3A | 4 | 0.9717 | 100 | 0.055 | Contact Map | 0.8 |
| 3gafA | 8 | 0.9717 | 100 | 0.056 | Contact Map | 0.824 |
Sequence Conservation (Image Generated using WebLogo v3)