| UniProt: | P0AEK2 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11318 | ||
| Length: | 244 (241) | ||
| Sequences: | 55339 | ||
| Seq/Len: | 229.62 |
| FABG
Paralog alert: 0.89 [within 20: 0.50] - ratio of genomes with paralogs Cluster includes: BDCA ENTA FABG FABI FOLM HCAB HDHA IDNO KDUD SRLD UCPA YBBO YCIK YDFG YGCW YGFF YGHA YOHF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 104_N | 112_S | 3.128 | 1.00 | |
| 104_N | 108_E | 2.864 | 1.00 | |
| 156_A | 160_G | 2.776 | 1.00 | |
| 62_D | 65_S | 2.677 | 1.00 | |
| 135_T | 162_S | 2.62 | 1.00 | |
| 8_A | 82_I | 2.292 | 1.00 | |
| 132_R | 175_T | 2.284 | 1.00 | |
| 74_R | 124_A | 2.277 | 1.00 | |
| 19_R | 23_E | 2.26 | 1.00 | |
| 39_E | 43_Q | 2.23 | 1.00 | |
| 137_G | 159_I | 2.178 | 1.00 | |
| 67_E | 120_A | 2.169 | 1.00 | |
| 126_M | 172_R | 2.133 | 1.00 | |
| 118_S | 165_L | 2.117 | 1.00 | |
| 85_N | 135_T | 2.116 | 1.00 | |
| 180_A | 234_T | 2.081 | 1.00 | |
| 185_E | 211_G | 2.033 | 1.00 | |
| 82_I | 223_A | 1.971 | 1.00 | |
| 24_T | 217_N | 1.959 | 1.00 | |
| 31_K | 52_N | 1.949 | 1.00 | |
| 108_E | 112_S | 1.941 | 1.00 | |
| 122_M | 169_V | 1.9 | 1.00 | |
| 70_L | 121_V | 1.884 | 1.00 | |
| 63_P | 100_D | 1.832 | 1.00 | |
| 35_T | 58_L | 1.824 | 1.00 | |
| 7_I | 31_K | 1.81 | 1.00 | |
| 24_T | 28_R | 1.804 | 1.00 | |
| 17_I | 184_I | 1.788 | 1.00 | |
| 24_T | 220_A | 1.764 | 1.00 | |
| 217_N | 226_E | 1.734 | 1.00 | |
| 114_V | 158_L | 1.723 | 1.00 | |
| 233_E | 236_H | 1.718 | 1.00 | |
| 110_N | 154_A | 1.714 | 1.00 | |
| 23_E | 48_Y | 1.707 | 1.00 | |
| 19_R | 45_I | 1.676 | 1.00 | |
| 72_K | 76_E | 1.669 | 1.00 | |
| 14_S | 36_A | 1.659 | 1.00 | |
| 38_S | 41_G | 1.649 | 1.00 | |
| 19_R | 48_Y | 1.639 | 1.00 | |
| 21_I | 219_V | 1.634 | 1.00 | |
| 162_S | 178_V | 1.627 | 1.00 | |
| 33_I | 77_F | 1.604 | 1.00 | |
| 218_A | 235_L | 1.601 | 1.00 | |
| 13_A | 34_G | 1.6 | 1.00 | |
| 111_L | 157_G | 1.587 | 1.00 | |
| 54_K | 76_E | 1.582 | 1.00 | |
| 42_A | 55_G | 1.571 | 1.00 | |
| 25_L | 223_A | 1.53 | 1.00 | |
| 33_I | 73_I | 1.515 | 1.00 | |
| 71_E | 75_A | 1.514 | 1.00 | |
| 107_I | 111_L | 1.506 | 1.00 | |
| 24_T | 27_A | 1.485 | 1.00 | |
| 28_R | 220_A | 1.481 | 1.00 | |
| 84_V | 136_I | 1.472 | 1.00 | |
| 35_T | 69_V | 1.46 | 1.00 | |
| 7_I | 79_E | 1.454 | 1.00 | |
| 39_E | 57_M | 1.451 | 1.00 | |
| 68_S | 72_K | 1.438 | 1.00 | |
| 15_R | 187_D | 1.438 | 1.00 | |
| 58_L | 65_S | 1.432 | 1.00 | |
| 132_R | 177_N | 1.431 | 1.00 | |
| 30_A | 82_I | 1.429 | 1.00 | |
| 99_K | 102_E | 1.416 | 1.00 | |
| 100_D | 116_R | 1.407 | 0.99 | |
| 67_E | 71_E | 1.406 | 0.99 | |
| 210_G | 229_Y | 1.387 | 0.99 | |
| 83_L | 117_L | 1.374 | 0.99 | |
| 72_K | 75_A | 1.367 | 0.99 | |
| 8_A | 25_L | 1.363 | 0.99 | |
| 5_G | 30_A | 1.348 | 0.99 | |
| 43_Q | 47_D | 1.331 | 0.99 | |
| 66_I | 117_L | 1.33 | 0.99 | |
| 85_N | 118_S | 1.32 | 0.99 | |
| 63_P | 116_R | 1.319 | 0.99 | |
| 46_S | 55_G | 1.296 | 0.99 | |
| 58_L | 69_V | 1.29 | 0.99 | |
| 56_L | 72_K | 1.284 | 0.99 | |
| 65_S | 68_S | 1.277 | 0.99 | |
| 8_A | 30_A | 1.272 | 0.99 | |
| 20_A | 23_E | 1.272 | 0.99 | |
| 137_G | 178_V | 1.27 | 0.99 | |
| 118_S | 133_I | 1.264 | 0.99 | |
| 63_P | 67_E | 1.26 | 0.99 | |
| 162_S | 176_V | 1.253 | 0.99 | |
| 179_V | 219_V | 1.235 | 0.98 | |
| 184_I | 210_G | 1.229 | 0.98 | |
| 3_F | 30_A | 1.226 | 0.98 | |
| 31_K | 51_A | 1.223 | 0.98 | |
| 112_S | 116_R | 1.209 | 0.98 | |
| 124_A | 128_K | 1.206 | 0.98 | |
| 22_A | 34_G | 1.205 | 0.98 | |
| 20_A | 213_Q | 1.198 | 0.98 | |
| 218_A | 237_V | 1.186 | 0.98 | |
| 25_L | 30_A | 1.183 | 0.98 | |
| 15_R | 41_G | 1.169 | 0.97 | |
| 80_V | 121_V | 1.15 | 0.97 | |
| 7_I | 33_I | 1.135 | 0.97 | |
| 56_L | 69_V | 1.125 | 0.97 | |
| 23_E | 27_A | 1.121 | 0.97 | |
| 165_L | 176_V | 1.118 | 0.96 | |
| 96_M | 126_M | 1.118 | 0.96 | |
| 79_E | 128_K | 1.116 | 0.96 | |
| 107_I | 112_S | 1.114 | 0.96 | |
| 64_A | 68_S | 1.113 | 0.96 | |
| 91_R | 105_D | 1.112 | 0.96 | |
| 83_L | 121_V | 1.094 | 0.96 | |
| 54_K | 77_F | 1.092 | 0.96 | |
| 31_K | 54_K | 1.087 | 0.96 | |
| 43_Q | 46_S | 1.084 | 0.96 | |
| 151_Y | 155_K | 1.084 | 0.96 | |
| 100_D | 112_S | 1.076 | 0.95 | |
| 9_L | 69_V | 1.076 | 0.95 | |
| 101_E | 105_D | 1.072 | 0.95 | |
| 24_T | 216_A | 1.07 | 0.95 | |
| 68_S | 71_E | 1.07 | 0.95 | |
| 115_F | 161_F | 1.06 | 0.95 | |
| 89_I | 109_T | 1.059 | 0.95 | |
| 86_N | 136_I | 1.058 | 0.95 | |
| 61_T | 105_D | 1.048 | 0.94 | |
| 142_T | 236_H | 1.044 | 0.94 | |
| 118_S | 161_F | 1.034 | 0.94 | |
| 94_L | 97_R | 1.031 | 0.94 | |
| 44_A | 48_Y | 1.023 | 0.93 | |
| 93_N | 102_E | 1.013 | 0.93 | |
| 26_A | 49_L | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3op4A | 2 | 1 | 100 | 0.05 | Contact Map | 0.753 |
| 2c07A | 1 | 0.9959 | 100 | 0.052 | Contact Map | 0.749 |
| 4bnwA | 4 | 1 | 100 | 0.054 | Contact Map | 0.778 |
| 4ag3A | 4 | 1 | 100 | 0.054 | Contact Map | 0.797 |
| 1vl8A | 2 | 1 | 100 | 0.056 | Contact Map | 0.799 |
| 3grpA | 4 | 1 | 100 | 0.057 | Contact Map | 0.863 |
| 4iinA | 4 | 0.9959 | 100 | 0.058 | Contact Map | 0.845 |
| 3ftpA | 4 | 1 | 100 | 0.058 | Contact Map | 0.849 |
| 3lylA | 4 | 1 | 100 | 0.06 | Contact Map | 0.809 |
| 3rihA | 4 | 1 | 100 | 0.063 | Contact Map | 0.806 |
Sequence Conservation (Image Generated using WebLogo v3)