| UniProt: | P0AEK4 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11528 | ||
| Length: | 262 (245) | ||
| Sequences: | 49714 | ||
| Seq/Len: | 202.91 |
| FABI
Paralog alert: 0.89 [within 20: 0.48] - ratio of genomes with paralogs Cluster includes: BDCA ENTA FABG FABI FOLM HCAB HDHA IDNO KDUD SRLD UCPA YBBO YCIK YDFG YGCW YGFF YGHA YOHF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 114_K | 122_Y | 3.28 | 1.00 | |
| 114_K | 118_D | 2.936 | 1.00 | |
| 67_E | 70_S | 2.852 | 1.00 | |
| 164_A | 168_A | 2.788 | 1.00 | |
| 143_T | 170_V | 2.584 | 1.00 | |
| 140_A | 183_R | 2.519 | 1.00 | |
| 79_G | 134_M | 2.369 | 1.00 | |
| 9_I | 87_G | 2.357 | 1.00 | |
| 22_Y | 26_Q | 2.348 | 1.00 | |
| 128_A | 173_M | 2.246 | 1.00 | |
| 72_D | 130_A | 2.223 | 1.00 | |
| 145_S | 167_E | 2.218 | 1.00 | |
| 188_S | 244_V | 2.194 | 1.00 | |
| 193_R | 221_T | 2.194 | 1.00 | |
| 27_A | 227_N | 2.138 | 1.00 | |
| 90_H | 143_T | 2.088 | 1.00 | |
| 87_G | 233_C | 2.076 | 1.00 | |
| 118_D | 122_Y | 1.985 | 1.00 | |
| 132_R | 177_M | 1.961 | 1.00 | |
| 75_F | 131_C | 1.96 | 1.00 | |
| 68_D | 110_R | 1.943 | 1.00 | |
| 27_A | 230_A | 1.896 | 1.00 | |
| 8_R | 34_E | 1.892 | 1.00 | |
| 27_A | 31_E | 1.885 | 1.00 | |
| 227_N | 236_L | 1.867 | 1.00 | |
| 20_I | 192_I | 1.847 | 1.00 | |
| 136_N | 180_E | 1.846 | 1.00 | |
| 38_T | 63_C | 1.843 | 1.00 | |
| 120_S | 162_A | 1.809 | 1.00 | |
| 243_E | 246_H | 1.803 | 1.00 | |
| 124_F | 166_L | 1.801 | 1.00 | |
| 24_I | 229_A | 1.786 | 1.00 | |
| 77_E | 81_V | 1.704 | 1.00 | |
| 170_V | 186_A | 1.704 | 1.00 | |
| 228_S | 245_V | 1.691 | 1.00 | |
| 76_A | 80_K | 1.638 | 1.00 | |
| 34_E | 57_S | 1.637 | 1.00 | |
| 31_E | 230_A | 1.615 | 1.00 | |
| 14_V | 37_F | 1.613 | 1.00 | |
| 28_M | 233_C | 1.611 | 1.00 | |
| 36_A | 78_L | 1.587 | 1.00 | |
| 36_A | 82_W | 1.578 | 1.00 | |
| 117_H | 121_S | 1.575 | 1.00 | |
| 38_T | 74_M | 1.556 | 1.00 | |
| 59_I | 81_V | 1.546 | 1.00 | |
| 121_S | 165_S | 1.536 | 1.00 | |
| 33_A | 87_G | 1.525 | 1.00 | |
| 73_T | 77_E | 1.525 | 1.00 | |
| 27_A | 30_R | 1.523 | 1.00 | |
| 109_T | 112_G | 1.522 | 1.00 | |
| 49_E | 53_A | 1.507 | 1.00 | |
| 220_V | 239_G | 1.497 | 1.00 | |
| 72_D | 76_A | 1.494 | 1.00 | |
| 63_C | 70_S | 1.491 | 1.00 | |
| 15_A | 39_Y | 1.478 | 1.00 | |
| 8_R | 84_K | 1.477 | 1.00 | |
| 110_R | 126_A | 1.467 | 1.00 | |
| 88_F | 127_M | 1.441 | 1.00 | |
| 9_I | 28_M | 1.439 | 1.00 | |
| 77_E | 80_K | 1.432 | 1.00 | |
| 26_Q | 54_Q | 1.43 | 1.00 | |
| 89_V | 144_L | 1.428 | 1.00 | |
| 140_A | 185_N | 1.414 | 1.00 | |
| 6_G | 33_A | 1.402 | 0.99 | |
| 187_I | 229_A | 1.366 | 0.99 | |
| 68_D | 126_A | 1.334 | 0.99 | |
| 71_I | 127_M | 1.329 | 0.99 | |
| 45_K | 49_E | 1.328 | 0.99 | |
| 25_A | 37_F | 1.316 | 0.99 | |
| 63_C | 74_M | 1.307 | 0.99 | |
| 70_S | 73_T | 1.306 | 0.99 | |
| 4_L | 33_A | 1.301 | 0.99 | |
| 90_H | 128_A | 1.297 | 0.99 | |
| 18_L | 195_L | 1.293 | 0.99 | |
| 192_I | 220_V | 1.292 | 0.99 | |
| 122_Y | 126_A | 1.273 | 0.99 | |
| 61_L | 77_E | 1.272 | 0.99 | |
| 145_S | 186_A | 1.27 | 0.99 | |
| 68_D | 72_D | 1.266 | 0.99 | |
| 228_S | 247_V | 1.255 | 0.99 | |
| 28_M | 33_A | 1.255 | 0.99 | |
| 23_G | 223_E | 1.247 | 0.99 | |
| 49_E | 52_A | 1.235 | 0.98 | |
| 23_G | 26_Q | 1.231 | 0.98 | |
| 9_I | 33_A | 1.23 | 0.98 | |
| 128_A | 141_L | 1.225 | 0.98 | |
| 42_D | 62_Q | 1.214 | 0.98 | |
| 170_V | 184_V | 1.211 | 0.98 | |
| 85_F | 131_C | 1.21 | 0.98 | |
| 173_M | 184_V | 1.209 | 0.98 | |
| 26_Q | 30_R | 1.197 | 0.98 | |
| 110_R | 122_Y | 1.167 | 0.97 | |
| 69_A | 73_T | 1.162 | 0.97 | |
| 27_A | 226_G | 1.161 | 0.97 | |
| 48_V | 60_V | 1.158 | 0.97 | |
| 88_F | 131_C | 1.145 | 0.97 | |
| 50_E | 54_Q | 1.145 | 0.97 | |
| 59_I | 82_W | 1.143 | 0.97 | |
| 8_R | 36_A | 1.142 | 0.97 | |
| 117_H | 122_Y | 1.112 | 0.96 | |
| 111_E | 115_I | 1.107 | 0.96 | |
| 94_F | 119_I | 1.106 | 0.96 | |
| 22_Y | 50_E | 1.102 | 0.96 | |
| 61_L | 74_M | 1.095 | 0.96 | |
| 150_E | 246_H | 1.091 | 0.96 | |
| 73_T | 76_A | 1.086 | 0.96 | |
| 125_V | 169_N | 1.081 | 0.95 | |
| 96_P | 115_I | 1.08 | 0.95 | |
| 113_F | 122_Y | 1.072 | 0.95 | |
| 186_A | 244_V | 1.067 | 0.95 | |
| 91_S | 144_L | 1.065 | 0.95 | |
| 10_L | 74_M | 1.062 | 0.95 | |
| 144_L | 229_A | 1.061 | 0.95 | |
| 231_F | 240_I | 1.061 | 0.95 | |
| 66_A | 115_I | 1.058 | 0.95 | |
| 24_I | 89_V | 1.058 | 0.95 | |
| 28_M | 230_A | 1.054 | 0.95 | |
| 167_E | 244_V | 1.038 | 0.94 | |
| 24_I | 226_G | 1.038 | 0.94 | |
| 47_R | 50_E | 1.036 | 0.94 | |
| 103_D | 106_N | 1.035 | 0.94 | |
| 48_V | 52_A | 1.034 | 0.94 | |
| 23_G | 222_I | 1.021 | 0.93 | |
| 159_M | 163_K | 1.016 | 0.93 | |
| 20_I | 24_I | 1.015 | 0.93 | |
| 22_Y | 51_F | 1.015 | 0.93 | |
| 128_A | 169_N | 1.014 | 0.93 | |
| 27_A | 223_E | 1.012 | 0.93 | |
| 218_R | 224_D | 1.009 | 0.93 | |
| 51_F | 55_L | 1.006 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3grkA | 8 | 0.9962 | 100 | 0.121 | Contact Map | 0.77 |
| 1vl8A | 2 | 0.9427 | 100 | 0.124 | Contact Map | 0.8 |
| 4egfA | 8 | 0.9427 | 100 | 0.128 | Contact Map | 0.833 |
| 2p91A | 4 | 0.9885 | 100 | 0.128 | Contact Map | 0.829 |
| 2rhcB | 2 | 0.9427 | 100 | 0.132 | Contact Map | 0.833 |
| 4j2hA | 1 | 0.9466 | 100 | 0.133 | Contact Map | 0.752 |
| 3v8bA | 4 | 0.9504 | 100 | 0.134 | Contact Map | 0.835 |
| 2c07A | 1 | 0.9313 | 100 | 0.135 | Contact Map | 0.74 |
| 3lf2A | 4 | 0.9466 | 100 | 0.136 | Contact Map | 0.856 |
| 1iy8A | 8 | 0.9504 | 100 | 0.136 | Contact Map | 0.875 |
Sequence Conservation (Image Generated using WebLogo v3)