| UniProt: | P33368 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12019 | ||
| Length: | 253 (243) | ||
| Sequences: | 52317 | ||
| Seq/Len: | 215.30 |
| YOHF
Paralog alert: 0.89 [within 20: 0.48] - ratio of genomes with paralogs Cluster includes: BDCA ENTA FABG FABI FOLM HCAB HDHA IDNO KDUD SRLD UCPA YBBO YCIK YDFG YGCW YGFF YGHA YOHF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 105_R | 113_D | 3.128 | 1.00 | |
| 105_R | 109_T | 2.863 | 1.00 | |
| 158_H | 162_G | 2.709 | 1.00 | |
| 63_N | 66_E | 2.686 | 1.00 | |
| 137_N | 164_T | 2.527 | 1.00 | |
| 75_I | 125_Q | 2.295 | 1.00 | |
| 134_R | 177_L | 2.287 | 1.00 | |
| 5_A | 83_V | 2.273 | 1.00 | |
| 37_E | 41_K | 2.248 | 1.00 | |
| 16_K | 20_L | 2.244 | 1.00 | |
| 68_A | 121_I | 2.177 | 1.00 | |
| 119_S | 167_M | 2.166 | 1.00 | |
| 127_V | 174_H | 2.137 | 1.00 | |
| 139_T | 161_G | 2.133 | 1.00 | |
| 187_A | 213_A | 2.11 | 1.00 | |
| 182_A | 236_S | 2.079 | 1.00 | |
| 21_L | 219_S | 2.045 | 1.00 | |
| 86_N | 137_N | 1.979 | 1.00 | |
| 109_T | 113_D | 1.949 | 1.00 | |
| 83_V | 225_C | 1.939 | 1.00 | |
| 28_D | 53_R | 1.903 | 1.00 | |
| 123_A | 171_L | 1.89 | 1.00 | |
| 64_L | 101_F | 1.863 | 1.00 | |
| 71_L | 122_A | 1.862 | 1.00 | |
| 32_T | 59_L | 1.822 | 1.00 | |
| 21_L | 222_V | 1.821 | 1.00 | |
| 21_L | 25_Q | 1.802 | 1.00 | |
| 4_V | 28_D | 1.797 | 1.00 | |
| 14_I | 186_I | 1.754 | 1.00 | |
| 219_S | 228_G | 1.742 | 1.00 | |
| 235_Q | 238_I | 1.729 | 1.00 | |
| 115_A | 160_L | 1.703 | 1.00 | |
| 20_L | 46_E | 1.696 | 1.00 | |
| 2_A | 27_F | 1.696 | 1.00 | |
| 111_D | 156_A | 1.686 | 1.00 | |
| 18_C | 221_V | 1.669 | 1.00 | |
| 73_K | 77_R | 1.66 | 1.00 | |
| 16_K | 46_E | 1.658 | 1.00 | |
| 164_T | 180_A | 1.653 | 1.00 | |
| 16_K | 43_T | 1.639 | 1.00 | |
| 30_G | 78_L | 1.582 | 1.00 | |
| 10_S | 31_I | 1.578 | 1.00 | |
| 55_E | 77_R | 1.578 | 1.00 | |
| 220_L | 237_L | 1.569 | 1.00 | |
| 11_D | 33_W | 1.544 | 1.00 | |
| 72_E | 76_Q | 1.54 | 1.00 | |
| 40_A | 56_I | 1.538 | 1.00 | |
| 27_F | 83_V | 1.527 | 1.00 | |
| 30_G | 74_L | 1.527 | 1.00 | |
| 25_Q | 222_V | 1.52 | 1.00 | |
| 22_L | 225_C | 1.518 | 1.00 | |
| 112_V | 159_A | 1.507 | 1.00 | |
| 108_F | 112_V | 1.49 | 1.00 | |
| 32_T | 70_A | 1.489 | 1.00 | |
| 21_L | 24_Q | 1.481 | 1.00 | |
| 69_L | 73_K | 1.462 | 1.00 | |
| 35_S | 39_G | 1.443 | 1.00 | |
| 59_L | 66_E | 1.441 | 1.00 | |
| 4_V | 80_R | 1.435 | 1.00 | |
| 68_A | 72_E | 1.433 | 1.00 | |
| 100_A | 103_E | 1.43 | 1.00 | |
| 85_V | 138_I | 1.426 | 1.00 | |
| 134_R | 179_N | 1.425 | 1.00 | |
| 73_K | 76_Q | 1.388 | 0.99 | |
| 84_L | 118_C | 1.379 | 0.99 | |
| 41_K | 45_R | 1.377 | 0.99 | |
| 212_G | 231_Y | 1.376 | 0.99 | |
| 101_F | 117_L | 1.371 | 0.99 | |
| 37_E | 58_Q | 1.36 | 0.99 | |
| 12_S | 189_P | 1.359 | 0.99 | |
| 5_A | 22_L | 1.353 | 0.99 | |
| 44_A | 48_V | 1.338 | 0.99 | |
| 67_G | 118_C | 1.315 | 0.99 | |
| 59_L | 70_A | 1.299 | 0.99 | |
| 64_L | 117_L | 1.294 | 0.99 | |
| 57_V | 73_K | 1.287 | 0.99 | |
| 86_N | 119_S | 1.274 | 0.99 | |
| 64_L | 68_A | 1.254 | 0.99 | |
| 66_E | 69_L | 1.252 | 0.99 | |
| 139_T | 180_A | 1.249 | 0.99 | |
| 164_T | 178_V | 1.242 | 0.98 | |
| 17_E | 20_L | 1.24 | 0.98 | |
| 186_I | 212_G | 1.238 | 0.98 | |
| 5_A | 27_F | 1.237 | 0.98 | |
| 181_V | 221_V | 1.233 | 0.98 | |
| 17_E | 215_H | 1.231 | 0.98 | |
| 113_D | 117_L | 1.225 | 0.98 | |
| 22_L | 27_F | 1.215 | 0.98 | |
| 44_A | 56_I | 1.214 | 0.98 | |
| 125_Q | 129_Q | 1.208 | 0.98 | |
| 19_A | 31_I | 1.204 | 0.98 | |
| 28_D | 52_V | 1.201 | 0.98 | |
| 119_S | 135_I | 1.194 | 0.98 | |
| 220_L | 239_V | 1.17 | 0.97 | |
| 4_V | 30_G | 1.152 | 0.97 | |
| 20_L | 24_Q | 1.143 | 0.97 | |
| 45_R | 49_S | 1.141 | 0.97 | |
| 81_I | 122_A | 1.139 | 0.97 | |
| 45_R | 48_V | 1.138 | 0.97 | |
| 21_L | 218_A | 1.126 | 0.97 | |
| 167_M | 178_V | 1.121 | 0.97 | |
| 12_S | 39_G | 1.117 | 0.96 | |
| 55_E | 78_L | 1.114 | 0.96 | |
| 108_F | 113_D | 1.104 | 0.96 | |
| 65_P | 69_L | 1.104 | 0.96 | |
| 92_T | 106_K | 1.099 | 0.96 | |
| 84_L | 122_A | 1.098 | 0.96 | |
| 57_V | 70_A | 1.097 | 0.96 | |
| 24_Q | 50_H | 1.083 | 0.96 | |
| 69_L | 72_E | 1.082 | 0.96 | |
| 101_F | 113_D | 1.08 | 0.95 | |
| 102_D | 106_K | 1.077 | 0.95 | |
| 116_F | 163_L | 1.076 | 0.95 | |
| 90_A | 110_V | 1.076 | 0.95 | |
| 35_S | 38_E | 1.076 | 0.95 | |
| 97_L | 127_V | 1.075 | 0.95 | |
| 80_R | 129_Q | 1.073 | 0.95 | |
| 144_H | 238_I | 1.06 | 0.95 | |
| 87_N | 138_I | 1.053 | 0.95 | |
| 28_D | 55_E | 1.046 | 0.94 | |
| 6_I | 70_A | 1.042 | 0.94 | |
| 94_A | 103_E | 1.04 | 0.94 | |
| 95_P | 98_D | 1.033 | 0.94 | |
| 41_K | 44_A | 1.032 | 0.94 | |
| 62_G | 106_K | 1.03 | 0.94 | |
| 17_E | 214_T | 1.028 | 0.94 | |
| 180_A | 236_S | 1.025 | 0.93 | |
| 18_C | 218_A | 1.022 | 0.93 | |
| 153_Y | 157_K | 1.017 | 0.93 | |
| 138_I | 221_V | 1.016 | 0.93 | |
| 104_W | 113_D | 1.008 | 0.93 | |
| 22_L | 222_V | 1.006 | 0.93 | |
| 115_A | 137_N | 1.003 | 0.93 | |
| 119_S | 163_L | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2c07A | 1 | 0.9605 | 100 | 0.104 | Contact Map | 0.749 |
| 3oidA | 4 | 0.9921 | 100 | 0.108 | Contact Map | 0.871 |
| 1vl8A | 2 | 0.9644 | 100 | 0.109 | Contact Map | 0.79 |
| 4bnwA | 4 | 0.9644 | 100 | 0.11 | Contact Map | 0.778 |
| 4ag3A | 4 | 0.9644 | 100 | 0.11 | Contact Map | 0.801 |
| 3rihA | 4 | 0.9881 | 100 | 0.111 | Contact Map | 0.801 |
| 3ftpA | 4 | 0.9644 | 100 | 0.111 | Contact Map | 0.85 |
| 3cxtA | 1 | 0.9881 | 100 | 0.111 | Contact Map | 0.692 |
| 1xq1A | 1 | 0.9921 | 100 | 0.112 | Contact Map | 0.646 |
| 1zemA | 8 | 0.9486 | 100 | 0.113 | Contact Map | 0.844 |
Sequence Conservation (Image Generated using WebLogo v3)