| UniProt: | P0AFS3 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13189 | ||
| Length: | 240 (236) | ||
| Sequences: | 51112 | ||
| Seq/Len: | 216.58 |
| FOLM
Paralog alert: 0.89 [within 20: 0.49] - ratio of genomes with paralogs Cluster includes: BDCA ENTA FABG FABI FOLM HCAB HDHA IDNO KDUD SRLD UCPA YBBO YCIK YDFG YGCW YGFF YGHA YOHF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 103_A | 111_N | 3.293 | 1.00 | |
| 103_A | 107_Q | 2.961 | 1.00 | |
| 61_T | 64_G | 2.855 | 1.00 | |
| 157_A | 161_N | 2.774 | 1.00 | |
| 136_H | 163_T | 2.642 | 1.00 | |
| 132_S | 175_K | 2.506 | 1.00 | |
| 73_L | 123_L | 2.435 | 1.00 | |
| 9_I | 81_A | 2.349 | 1.00 | |
| 20_L | 24_W | 2.324 | 1.00 | |
| 66_M | 119_A | 2.276 | 1.00 | |
| 117_N | 166_F | 2.249 | 1.00 | |
| 180_A | 230_S | 2.202 | 1.00 | |
| 138_T | 160_D | 2.202 | 1.00 | |
| 185_L | 209_G | 2.159 | 1.00 | |
| 25_H | 215_D | 2.095 | 1.00 | |
| 84_H | 136_H | 2.078 | 1.00 | |
| 81_A | 221_L | 2.069 | 1.00 | |
| 107_Q | 111_N | 2.012 | 1.00 | |
| 121_E | 170_L | 1.995 | 1.00 | |
| 69_A | 120_L | 1.953 | 1.00 | |
| 62_N | 99_A | 1.941 | 1.00 | |
| 25_H | 29_Q | 1.916 | 1.00 | |
| 25_H | 218_D | 1.913 | 1.00 | |
| 36_S | 57_A | 1.896 | 1.00 | |
| 8_P | 32_P | 1.85 | 1.00 | |
| 229_R | 232_P | 1.838 | 1.00 | |
| 215_D | 224_C | 1.799 | 1.00 | |
| 18_I | 184_I | 1.776 | 1.00 | |
| 22_L | 217_V | 1.766 | 1.00 | |
| 109_H | 155_S | 1.766 | 1.00 | |
| 113_P | 159_L | 1.759 | 1.00 | |
| 71_E | 75_S | 1.743 | 1.00 | |
| 216_L | 231_F | 1.738 | 1.00 | |
| 163_T | 178_S | 1.712 | 1.00 | |
| 15_G | 37_Y | 1.662 | 1.00 | |
| 14_G | 35_V | 1.66 | 1.00 | |
| 31_Q | 81_A | 1.659 | 1.00 | |
| 110_V | 158_A | 1.654 | 1.00 | |
| 29_Q | 218_D | 1.633 | 1.00 | |
| 70_D | 74_K | 1.622 | 1.00 | |
| 34_I | 76_T | 1.616 | 1.00 | |
| 106_M | 110_V | 1.605 | 1.00 | |
| 34_I | 72_V | 1.593 | 1.00 | |
| 26_F | 221_L | 1.586 | 1.00 | |
| 53_Q | 75_S | 1.579 | 1.00 | |
| 36_S | 68_F | 1.561 | 1.00 | |
| 67_A | 71_E | 1.544 | 1.00 | |
| 25_H | 28_N | 1.525 | 1.00 | |
| 208_P | 225_F | 1.505 | 1.00 | |
| 57_A | 64_G | 1.503 | 1.00 | |
| 98_L | 101_V | 1.497 | 1.00 | |
| 66_M | 70_D | 1.492 | 1.00 | |
| 8_P | 78_G | 1.47 | 1.00 | |
| 83_L | 137_F | 1.465 | 1.00 | |
| 9_I | 26_F | 1.462 | 1.00 | |
| 82_I | 116_L | 1.461 | 1.00 | |
| 99_A | 115_L | 1.456 | 1.00 | |
| 132_S | 177_N | 1.443 | 1.00 | |
| 71_E | 74_K | 1.441 | 1.00 | |
| 40_H | 56_Q | 1.384 | 0.99 | |
| 62_N | 115_L | 1.374 | 0.99 | |
| 57_A | 68_F | 1.361 | 0.99 | |
| 65_V | 116_L | 1.358 | 0.99 | |
| 23_A | 35_V | 1.354 | 0.99 | |
| 64_G | 67_A | 1.345 | 0.99 | |
| 55_I | 71_E | 1.337 | 0.99 | |
| 62_N | 66_M | 1.317 | 0.99 | |
| 84_H | 117_N | 1.315 | 0.99 | |
| 138_T | 178_S | 1.311 | 0.99 | |
| 179_I | 217_V | 1.305 | 0.99 | |
| 184_I | 208_P | 1.304 | 0.99 | |
| 216_L | 233_L | 1.292 | 0.99 | |
| 9_I | 31_Q | 1.286 | 0.99 | |
| 111_N | 115_L | 1.281 | 0.99 | |
| 20_L | 46_G | 1.261 | 0.99 | |
| 163_T | 176_V | 1.257 | 0.99 | |
| 21_A | 24_W | 1.25 | 0.99 | |
| 79_L | 120_L | 1.249 | 0.99 | |
| 26_F | 31_Q | 1.247 | 0.99 | |
| 39_T | 42_P | 1.239 | 0.98 | |
| 117_N | 134_I | 1.231 | 0.98 | |
| 21_A | 211_K | 1.226 | 0.98 | |
| 166_F | 176_V | 1.222 | 0.98 | |
| 63_D | 67_A | 1.201 | 0.98 | |
| 24_W | 28_N | 1.197 | 0.98 | |
| 99_A | 111_N | 1.187 | 0.98 | |
| 53_Q | 76_T | 1.181 | 0.98 | |
| 82_I | 120_L | 1.172 | 0.98 | |
| 219_Y | 226_V | 1.16 | 0.97 | |
| 25_H | 214_I | 1.151 | 0.97 | |
| 106_M | 111_N | 1.143 | 0.97 | |
| 95_G | 125_R | 1.14 | 0.97 | |
| 55_I | 68_F | 1.14 | 0.97 | |
| 35_V | 52_A | 1.137 | 0.97 | |
| 90_M | 104_C | 1.134 | 0.97 | |
| 88_A | 108_I | 1.134 | 0.97 | |
| 143_E | 232_P | 1.132 | 0.97 | |
| 67_A | 70_D | 1.117 | 0.96 | |
| 100_D | 104_C | 1.111 | 0.96 | |
| 32_P | 53_Q | 1.11 | 0.96 | |
| 10_L | 68_F | 1.107 | 0.96 | |
| 8_P | 34_I | 1.1 | 0.96 | |
| 114_Y | 162_M | 1.1 | 0.96 | |
| 44_I | 54_C | 1.098 | 0.96 | |
| 44_I | 48_I | 1.096 | 0.96 | |
| 92_E | 101_V | 1.084 | 0.96 | |
| 45_D | 48_I | 1.083 | 0.96 | |
| 60_S | 104_C | 1.08 | 0.95 | |
| 93_K | 96_A | 1.077 | 0.95 | |
| 178_S | 230_S | 1.076 | 0.95 | |
| 137_F | 217_V | 1.074 | 0.95 | |
| 24_W | 50_A | 1.059 | 0.95 | |
| 45_D | 49_N | 1.051 | 0.94 | |
| 206_T | 212_E | 1.05 | 0.94 | |
| 152_Y | 156_K | 1.05 | 0.94 | |
| 26_F | 218_D | 1.048 | 0.94 | |
| 102_L | 111_N | 1.042 | 0.94 | |
| 85_N | 137_F | 1.041 | 0.94 | |
| 22_L | 83_L | 1.034 | 0.94 | |
| 160_D | 230_S | 1.031 | 0.94 | |
| 113_P | 136_H | 1.031 | 0.94 | |
| 117_N | 162_M | 1.03 | 0.94 | |
| 59_F | 112_T | 1.023 | 0.93 | |
| 143_E | 180_A | 1.021 | 0.93 | |
| 18_I | 22_L | 1.012 | 0.93 | |
| 16_R | 20_L | 1.01 | 0.93 | |
| 22_L | 214_I | 1.01 | 0.93 | |
| 123_L | 127_H | 1.009 | 0.93 | |
| 21_A | 210_E | 1.008 | 0.93 | |
| 55_I | 75_S | 1.007 | 0.93 | |
| 40_H | 54_C | 1.007 | 0.93 | |
| 25_H | 211_K | 1.005 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3pk0A | 4 | 0.9917 | 100 | 0.063 | Contact Map | 0.772 |
| 2c07A | 1 | 0.9875 | 100 | 0.065 | Contact Map | 0.751 |
| 1vl8A | 2 | 0.9917 | 100 | 0.065 | Contact Map | 0.789 |
| 4g81D | 4 | 0.9958 | 100 | 0.065 | Contact Map | 0.821 |
| 3rihA | 4 | 0.9917 | 100 | 0.066 | Contact Map | 0.831 |
| 3op4A | 2 | 0.9875 | 100 | 0.067 | Contact Map | 0.764 |
| 4j2hA | 1 | 0.9875 | 100 | 0.068 | Contact Map | 0.755 |
| 4iboA | 4 | 0.9917 | 100 | 0.068 | Contact Map | 0.843 |
| 4egfA | 8 | 0.9958 | 100 | 0.07 | Contact Map | 0.831 |
| 3grpA | 4 | 0.9875 | 100 | 0.071 | Contact Map | 0.894 |
Sequence Conservation (Image Generated using WebLogo v3)