| UniProt: | P31808 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11759 | ||
| Length: | 252 (235) | ||
| Sequences: | 53756 | ||
| Seq/Len: | 228.75 |
| YCIK
Paralog alert: 0.88 [within 20: 0.49] - ratio of genomes with paralogs Cluster includes: BDCA ENTA FABG FABI FOLM HCAB HDHA IDNO KDUD SRLD UCPA YBBO YCIK YDFG YGCW YGFF YGHA YOHF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 118_Q | 126_N | 3.099 | 1.00 | |
| 118_Q | 122_Q | 2.778 | 1.00 | |
| 75_T | 78_N | 2.709 | 1.00 | |
| 170_F | 174_G | 2.656 | 1.00 | |
| 149_F | 176_M | 2.54 | 1.00 | |
| 146_S | 188_R | 2.279 | 1.00 | |
| 26_R | 30_M | 2.275 | 1.00 | |
| 15_I | 95_G | 2.269 | 1.00 | |
| 46_E | 50_R | 2.252 | 1.00 | |
| 87_A | 138_L | 2.21 | 1.00 | |
| 140_L | 186_R | 2.198 | 1.00 | |
| 132_T | 179_L | 2.144 | 1.00 | |
| 80_Q | 134_A | 2.134 | 1.00 | |
| 193_N | 239_T | 2.104 | 1.00 | |
| 151_S | 173_E | 2.102 | 1.00 | |
| 198_R | 216_T | 2.082 | 1.00 | |
| 98_H | 149_F | 2.004 | 1.00 | |
| 31_T | 222_P | 1.994 | 1.00 | |
| 122_Q | 126_N | 1.926 | 1.00 | |
| 136_L | 183_Y | 1.898 | 1.00 | |
| 95_G | 228_M | 1.856 | 1.00 | |
| 76_S | 114_P | 1.826 | 1.00 | |
| 83_A | 135_L | 1.821 | 1.00 | |
| 14_I | 38_T | 1.802 | 1.00 | |
| 31_T | 35_Y | 1.79 | 1.00 | |
| 42_L | 69_L | 1.787 | 1.00 | |
| 31_T | 225_L | 1.764 | 1.00 | |
| 30_M | 55_H | 1.734 | 1.00 | |
| 24_I | 197_T | 1.726 | 1.00 | |
| 238_M | 241_D | 1.701 | 1.00 | |
| 124_N | 168_S | 1.694 | 1.00 | |
| 128_T | 172_T | 1.688 | 1.00 | |
| 26_R | 52_V | 1.681 | 1.00 | |
| 26_R | 55_H | 1.659 | 1.00 | |
| 222_P | 231_D | 1.654 | 1.00 | |
| 28_A | 224_Y | 1.647 | 1.00 | |
| 176_M | 191_C | 1.632 | 1.00 | |
| 85_R | 89_N | 1.631 | 1.00 | |
| 20_A | 41_L | 1.618 | 1.00 | |
| 21_S | 43_G | 1.584 | 1.00 | |
| 45_N | 48_K | 1.582 | 1.00 | |
| 223_L | 240_F | 1.562 | 1.00 | |
| 38_T | 63_Q | 1.546 | 1.00 | |
| 125_V | 171_A | 1.541 | 1.00 | |
| 40_I | 90_Y | 1.535 | 1.00 | |
| 121_M | 125_V | 1.51 | 1.00 | |
| 84_Q | 88_V | 1.496 | 1.00 | |
| 32_Y | 228_M | 1.495 | 1.00 | |
| 49_L | 66_W | 1.489 | 1.00 | |
| 31_T | 34_R | 1.489 | 1.00 | |
| 35_Y | 225_L | 1.449 | 1.00 | |
| 81_Q | 85_R | 1.446 | 1.00 | |
| 14_I | 92_R | 1.446 | 1.00 | |
| 40_I | 86_I | 1.445 | 1.00 | |
| 42_L | 82_L | 1.439 | 1.00 | |
| 69_L | 78_N | 1.427 | 1.00 | |
| 80_Q | 84_Q | 1.425 | 1.00 | |
| 37_A | 95_G | 1.418 | 1.00 | |
| 97_L | 150_T | 1.416 | 1.00 | |
| 50_R | 54_S | 1.403 | 0.99 | |
| 22_D | 200_A | 1.402 | 0.99 | |
| 65_Q | 89_N | 1.398 | 0.99 | |
| 46_E | 68_I | 1.395 | 0.99 | |
| 113_N | 116_V | 1.391 | 0.99 | |
| 15_I | 32_Y | 1.374 | 0.99 | |
| 85_R | 88_V | 1.354 | 0.99 | |
| 114_P | 130_M | 1.339 | 0.99 | |
| 12_D | 37_A | 1.332 | 0.99 | |
| 146_S | 190_N | 1.327 | 0.99 | |
| 96_V | 131_L | 1.322 | 0.99 | |
| 79_C | 131_L | 1.312 | 0.99 | |
| 76_S | 130_M | 1.31 | 0.99 | |
| 151_S | 191_C | 1.309 | 0.99 | |
| 215_K | 234_R | 1.307 | 0.99 | |
| 69_L | 82_L | 1.269 | 0.99 | |
| 53_A | 57_N | 1.258 | 0.99 | |
| 27_E | 30_M | 1.254 | 0.99 | |
| 78_N | 81_Q | 1.253 | 0.99 | |
| 15_I | 37_A | 1.253 | 0.99 | |
| 98_H | 132_T | 1.247 | 0.99 | |
| 67_F | 85_R | 1.246 | 0.98 | |
| 29_A | 41_L | 1.222 | 0.98 | |
| 70_D | 74_C | 1.221 | 0.98 | |
| 132_T | 147_L | 1.221 | 0.98 | |
| 53_A | 66_W | 1.22 | 0.98 | |
| 38_T | 62_R | 1.22 | 0.98 | |
| 76_S | 80_Q | 1.216 | 0.98 | |
| 176_M | 189_V | 1.209 | 0.98 | |
| 126_N | 130_M | 1.207 | 0.98 | |
| 10_L | 37_A | 1.203 | 0.98 | |
| 32_Y | 37_A | 1.195 | 0.98 | |
| 192_I | 224_Y | 1.192 | 0.98 | |
| 138_L | 142_S | 1.187 | 0.98 | |
| 14_I | 40_I | 1.182 | 0.98 | |
| 223_L | 242_A | 1.177 | 0.98 | |
| 93_L | 135_L | 1.172 | 0.98 | |
| 27_E | 218_A | 1.166 | 0.97 | |
| 197_T | 215_K | 1.143 | 0.97 | |
| 54_S | 57_N | 1.133 | 0.97 | |
| 31_T | 221_M | 1.13 | 0.97 | |
| 114_P | 126_N | 1.12 | 0.96 | |
| 77_E | 81_Q | 1.116 | 0.96 | |
| 22_D | 48_K | 1.116 | 0.96 | |
| 179_L | 189_V | 1.115 | 0.96 | |
| 34_R | 59_E | 1.099 | 0.96 | |
| 30_M | 34_R | 1.098 | 0.96 | |
| 102_L | 123_V | 1.097 | 0.96 | |
| 121_M | 126_N | 1.095 | 0.96 | |
| 54_S | 58_E | 1.09 | 0.96 | |
| 96_V | 135_L | 1.088 | 0.96 | |
| 67_F | 82_L | 1.078 | 0.95 | |
| 92_R | 142_S | 1.07 | 0.95 | |
| 110_S | 140_L | 1.068 | 0.95 | |
| 156_R | 241_D | 1.067 | 0.95 | |
| 81_Q | 84_Q | 1.061 | 0.95 | |
| 50_R | 53_A | 1.05 | 0.94 | |
| 129_F | 175_M | 1.04 | 0.94 | |
| 115_Q | 119_D | 1.039 | 0.94 | |
| 165_Y | 169_K | 1.035 | 0.94 | |
| 99_N | 150_T | 1.034 | 0.94 | |
| 191_C | 239_T | 1.03 | 0.94 | |
| 27_E | 217_P | 1.025 | 0.93 | |
| 128_T | 149_F | 1.015 | 0.93 | |
| 108_P | 111_E | 1.01 | 0.93 | |
| 28_A | 221_M | 1.007 | 0.93 | |
| 132_T | 175_M | 1.002 | 0.92 | |
| 226_W | 235_K | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3f1lA | 2 | 1 | 100 | 0.094 | Contact Map | 0.797 |
| 4fn4A | 4 | 0.9563 | 100 | 0.141 | Contact Map | 0.944 |
| 2et6A | 1 | 0.9444 | 100 | 0.141 | Contact Map | 0.735 |
| 1vl8A | 2 | 0.9762 | 100 | 0.141 | Contact Map | 0.798 |
| 3cxtA | 1 | 0.9841 | 100 | 0.142 | Contact Map | 0.706 |
| 2c07A | 1 | 0.9683 | 100 | 0.143 | Contact Map | 0.764 |
| 3v8bA | 4 | 0.9802 | 100 | 0.144 | Contact Map | 0.856 |
| 4j2hA | 1 | 0.9722 | 100 | 0.145 | Contact Map | 0.754 |
| 1iy8A | 8 | 0.9841 | 100 | 0.147 | Contact Map | 0.896 |
| 3lf2A | 4 | 0.9643 | 100 | 0.148 | Contact Map | 0.839 |
Sequence Conservation (Image Generated using WebLogo v3)