| UniProt: | P39333 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12528 | ||
| Length: | 237 (234) | ||
| Sequences: | 55017 | ||
| Seq/Len: | 235.12 |
| BDCA
Paralog alert: 0.89 [within 20: 0.50] - ratio of genomes with paralogs Cluster includes: BDCA ENTA FABG FABI FOLM HCAB HDHA IDNO KDUD SRLD UCPA YBBO YCIK YDFG YGCW YGFF YGHA YOHF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 100_D | 108_H | 3.33 | 1.00 | |
| 100_D | 104_K | 3.029 | 1.00 | |
| 151_S | 155_G | 2.896 | 1.00 | |
| 129_I | 157_A | 2.718 | 1.00 | |
| 62_D | 65_A | 2.403 | 1.00 | |
| 9_V | 78_I | 2.401 | 1.00 | |
| 20_A | 24_R | 2.389 | 1.00 | |
| 126_R | 170_T | 2.358 | 1.00 | |
| 114_S | 160_L | 2.267 | 1.00 | |
| 131_G | 154_Q | 2.255 | 1.00 | |
| 41_K | 45_K | 2.252 | 1.00 | |
| 180_D | 205_Q | 2.218 | 1.00 | |
| 175_Q | 228_M | 2.208 | 1.00 | |
| 25_R | 211_G | 2.131 | 1.00 | |
| 104_K | 108_H | 2.115 | 1.00 | |
| 81_V | 129_I | 2.102 | 1.00 | |
| 118_A | 164_F | 2.033 | 1.00 | |
| 78_I | 217_A | 2.017 | 1.00 | |
| 32_N | 54_T | 2.002 | 1.00 | |
| 8_T | 32_N | 1.979 | 1.00 | |
| 36_T | 58_T | 1.929 | 1.00 | |
| 25_R | 214_A | 1.91 | 1.00 | |
| 25_R | 29_D | 1.905 | 1.00 | |
| 18_I | 179_I | 1.854 | 1.00 | |
| 211_G | 220_E | 1.851 | 1.00 | |
| 227_A | 230_T | 1.85 | 1.00 | |
| 63_R | 96_A | 1.81 | 1.00 | |
| 110_P | 153_L | 1.799 | 1.00 | |
| 24_R | 50_E | 1.781 | 1.00 | |
| 106_N | 149_S | 1.778 | 1.00 | |
| 20_A | 47_L | 1.76 | 1.00 | |
| 22_I | 213_V | 1.728 | 1.00 | |
| 157_A | 173_V | 1.718 | 1.00 | |
| 20_A | 50_E | 1.706 | 1.00 | |
| 212_M | 229_H | 1.7 | 1.00 | |
| 67_I | 116_E | 1.691 | 1.00 | |
| 14_G | 35_F | 1.689 | 1.00 | |
| 107_I | 152_A | 1.667 | 1.00 | |
| 34_R | 73_S | 1.649 | 1.00 | |
| 44_A | 55_A | 1.644 | 1.00 | |
| 103_F | 107_I | 1.605 | 1.00 | |
| 26_F | 217_A | 1.594 | 1.00 | |
| 25_R | 28_T | 1.589 | 1.00 | |
| 8_T | 75_A | 1.575 | 1.00 | |
| 29_D | 214_A | 1.569 | 1.00 | |
| 80_V | 130_I | 1.564 | 1.00 | |
| 126_R | 172_N | 1.554 | 1.00 | |
| 40_S | 43_A | 1.552 | 1.00 | |
| 31_A | 78_I | 1.512 | 1.00 | |
| 96_A | 112_H | 1.492 | 1.00 | |
| 16_R | 182_D | 1.491 | 1.00 | |
| 15_S | 37_Y | 1.487 | 1.00 | |
| 95_N | 98_D | 1.478 | 1.00 | |
| 204_G | 223_F | 1.449 | 1.00 | |
| 79_L | 113_A | 1.447 | 1.00 | |
| 9_V | 26_F | 1.433 | 1.00 | |
| 45_K | 49_Q | 1.422 | 1.00 | |
| 48_A | 55_A | 1.417 | 1.00 | |
| 6_G | 31_A | 1.415 | 1.00 | |
| 67_I | 71_R | 1.4 | 0.99 | |
| 81_V | 114_S | 1.385 | 0.99 | |
| 41_K | 57_F | 1.365 | 0.99 | |
| 21_A | 24_R | 1.357 | 0.99 | |
| 131_G | 173_V | 1.34 | 0.99 | |
| 9_V | 31_A | 1.335 | 0.99 | |
| 157_A | 171_I | 1.315 | 0.99 | |
| 114_S | 127_I | 1.304 | 0.99 | |
| 108_H | 112_H | 1.303 | 0.99 | |
| 8_T | 34_R | 1.297 | 0.99 | |
| 21_A | 207_E | 1.288 | 0.99 | |
| 26_F | 31_A | 1.283 | 0.99 | |
| 63_R | 112_H | 1.278 | 0.99 | |
| 179_I | 204_G | 1.277 | 0.99 | |
| 122_P | 167_R | 1.273 | 0.99 | |
| 23_V | 35_F | 1.269 | 0.99 | |
| 212_M | 231_I | 1.258 | 0.99 | |
| 4_F | 31_A | 1.254 | 0.99 | |
| 174_V | 213_V | 1.242 | 0.98 | |
| 76_L | 117_A | 1.24 | 0.98 | |
| 58_T | 65_A | 1.22 | 0.98 | |
| 87_V | 101_R | 1.2 | 0.98 | |
| 160_L | 171_I | 1.193 | 0.98 | |
| 24_R | 28_T | 1.191 | 0.98 | |
| 103_F | 108_H | 1.186 | 0.98 | |
| 79_L | 117_A | 1.182 | 0.98 | |
| 16_R | 43_A | 1.179 | 0.98 | |
| 25_R | 210_A | 1.179 | 0.98 | |
| 32_N | 53_A | 1.148 | 0.97 | |
| 96_A | 108_H | 1.147 | 0.97 | |
| 65_A | 68_D | 1.146 | 0.97 | |
| 45_K | 48_A | 1.141 | 0.97 | |
| 85_I | 105_I | 1.14 | 0.97 | |
| 111_Y | 156_M | 1.134 | 0.97 | |
| 82_N | 130_I | 1.113 | 0.96 | |
| 97_D | 101_R | 1.11 | 0.96 | |
| 61_A | 101_R | 1.108 | 0.96 | |
| 146_Y | 150_K | 1.099 | 0.96 | |
| 89_G | 98_D | 1.093 | 0.96 | |
| 8_T | 73_S | 1.089 | 0.96 | |
| 130_I | 213_V | 1.089 | 0.96 | |
| 90_E | 93_E | 1.089 | 0.96 | |
| 114_S | 156_M | 1.087 | 0.96 | |
| 173_V | 228_M | 1.076 | 0.95 | |
| 110_P | 129_I | 1.073 | 0.95 | |
| 34_R | 56_V | 1.064 | 0.95 | |
| 154_Q | 228_M | 1.059 | 0.95 | |
| 46_R | 50_E | 1.056 | 0.95 | |
| 21_A | 206_P | 1.051 | 0.94 | |
| 7_K | 77_D | 1.047 | 0.94 | |
| 70_V | 117_A | 1.044 | 0.94 | |
| 26_F | 214_A | 1.041 | 0.94 | |
| 27_V | 51_T | 1.04 | 0.94 | |
| 99_I | 108_H | 1.031 | 0.94 | |
| 22_I | 210_A | 1.027 | 0.94 | |
| 25_R | 207_E | 1.027 | 0.94 | |
| 85_I | 101_R | 1.026 | 0.94 | |
| 215_W | 224_V | 1.024 | 0.93 | |
| 66_V | 113_A | 1.022 | 0.93 | |
| 60_S | 109_A | 1.011 | 0.93 | |
| 22_I | 80_V | 1.01 | 0.93 | |
| 18_I | 22_I | 1.009 | 0.93 | |
| 46_R | 49_Q | 1.006 | 0.93 | |
| 16_R | 20_A | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4fgsA | 4 | 0.9916 | 100 | 0.045 | Contact Map | 0.866 |
| 3op4A | 2 | 0.9916 | 100 | 0.045 | Contact Map | 0.798 |
| 4i5fA | 8 | 0.9916 | 100 | 0.047 | Contact Map | 0.899 |
| 4esoA | 4 | 0.9873 | 100 | 0.049 | Contact Map | 0.814 |
| 1vl8A | 2 | 0.9916 | 100 | 0.05 | Contact Map | 0.814 |
| 3grpA | 4 | 0.9916 | 100 | 0.05 | Contact Map | 0.869 |
| 2c07A | 1 | 0.9916 | 100 | 0.052 | Contact Map | 0.771 |
| 2a4kA | 2 | 0.9873 | 100 | 0.052 | Contact Map | 0.685 |
| 4j2hA | 1 | 0.9916 | 100 | 0.053 | Contact Map | 0.754 |
| 3v2gA | 1 | 1 | 100 | 0.054 | Contact Map | 0.741 |
Sequence Conservation (Image Generated using WebLogo v3)