| UniProt: | P15047 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10259 | ||
| Length: | 248 (240) | ||
| Sequences: | 48734 | ||
| Seq/Len: | 203.06 |
| ENTA
Paralog alert: 0.89 [within 20: 0.48] - ratio of genomes with paralogs Cluster includes: BDCA ENTA FABG FABI FOLM HCAB HDHA IDNO KDUD SRLD UCPA YBBO YCIK YDFG YGCW YGFF YGHA YOHF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 97_Q | 105_G | 3.278 | 1.00 | |
| 97_Q | 101_A | 2.971 | 1.00 | |
| 55_D | 58_Q | 2.859 | 1.00 | |
| 149_A | 153_S | 2.764 | 1.00 | |
| 128_T | 155_A | 2.62 | 1.00 | |
| 125_A | 168_R | 2.473 | 1.00 | |
| 67_L | 117_Q | 2.395 | 1.00 | |
| 19_Y | 23_L | 2.352 | 1.00 | |
| 8_V | 75_A | 2.341 | 1.00 | |
| 130_A | 152_K | 2.264 | 1.00 | |
| 111_F | 158_V | 2.239 | 1.00 | |
| 60_A | 113_Q | 2.232 | 1.00 | |
| 173_S | 237_D | 2.212 | 1.00 | |
| 178_D | 214_R | 2.189 | 1.00 | |
| 119_R | 165_S | 2.16 | 1.00 | |
| 24_A | 220_N | 2.102 | 1.00 | |
| 75_A | 226_A | 2.054 | 1.00 | |
| 78_N | 128_T | 2.048 | 1.00 | |
| 63_C | 114_T | 1.978 | 1.00 | |
| 31_K | 44_Y | 1.971 | 1.00 | |
| 101_A | 105_G | 1.956 | 1.00 | |
| 115_M | 162_L | 1.94 | 1.00 | |
| 24_A | 223_L | 1.925 | 1.00 | |
| 56_A | 93_K | 1.921 | 1.00 | |
| 7_N | 31_K | 1.908 | 1.00 | |
| 24_A | 28_A | 1.905 | 1.00 | |
| 35_F | 51_M | 1.847 | 1.00 | |
| 17_I | 177_T | 1.817 | 1.00 | |
| 236_Q | 239_V | 1.815 | 1.00 | |
| 107_A | 151_L | 1.809 | 1.00 | |
| 103_N | 147_S | 1.797 | 1.00 | |
| 21_T | 222_I | 1.795 | 1.00 | |
| 220_N | 229_L | 1.781 | 1.00 | |
| 155_A | 171_V | 1.756 | 1.00 | |
| 221_T | 238_I | 1.749 | 1.00 | |
| 65_R | 69_E | 1.695 | 1.00 | |
| 13_A | 34_G | 1.687 | 1.00 | |
| 14_G | 36_D | 1.674 | 1.00 | |
| 64_Q | 68_A | 1.658 | 1.00 | |
| 25_F | 226_A | 1.638 | 1.00 | |
| 100_F | 104_V | 1.61 | 1.00 | |
| 28_A | 223_L | 1.606 | 1.00 | |
| 33_T | 70_T | 1.602 | 1.00 | |
| 104_V | 150_A | 1.595 | 1.00 | |
| 33_T | 66_L | 1.59 | 1.00 | |
| 35_F | 62_V | 1.554 | 1.00 | |
| 30_A | 75_A | 1.534 | 1.00 | |
| 24_A | 27_E | 1.533 | 1.00 | |
| 60_A | 64_Q | 1.529 | 1.00 | |
| 61_Q | 65_R | 1.526 | 1.00 | |
| 46_F | 69_E | 1.522 | 1.00 | |
| 51_M | 58_Q | 1.507 | 1.00 | |
| 92_S | 95_D | 1.501 | 1.00 | |
| 7_N | 72_R | 1.497 | 1.00 | |
| 213_A | 232_H | 1.49 | 1.00 | |
| 93_K | 109_N | 1.468 | 1.00 | |
| 76_L | 110_L | 1.463 | 1.00 | |
| 8_V | 25_F | 1.452 | 1.00 | |
| 65_R | 68_A | 1.432 | 1.00 | |
| 77_V | 129_V | 1.428 | 1.00 | |
| 5_G | 30_A | 1.421 | 1.00 | |
| 125_A | 170_N | 1.42 | 1.00 | |
| 15_K | 180_D | 1.415 | 1.00 | |
| 39_F | 50_V | 1.394 | 0.99 | |
| 22_A | 34_G | 1.394 | 0.99 | |
| 172_V | 222_I | 1.375 | 0.99 | |
| 59_V | 110_L | 1.353 | 0.99 | |
| 56_A | 109_N | 1.351 | 0.99 | |
| 177_T | 213_A | 1.34 | 0.99 | |
| 51_M | 62_V | 1.327 | 0.99 | |
| 31_K | 43_Q | 1.318 | 0.99 | |
| 58_Q | 61_Q | 1.306 | 0.99 | |
| 56_A | 60_A | 1.294 | 0.99 | |
| 49_E | 65_R | 1.292 | 0.99 | |
| 221_T | 240_V | 1.281 | 0.99 | |
| 130_A | 171_V | 1.274 | 0.99 | |
| 78_N | 111_F | 1.267 | 0.99 | |
| 105_G | 109_N | 1.267 | 0.99 | |
| 3_F | 30_A | 1.264 | 0.99 | |
| 117_Q | 121_Q | 1.263 | 0.99 | |
| 8_V | 30_A | 1.262 | 0.99 | |
| 20_A | 216_Q | 1.246 | 0.98 | |
| 73_L | 114_T | 1.241 | 0.98 | |
| 111_F | 126_I | 1.239 | 0.98 | |
| 158_V | 169_C | 1.238 | 0.98 | |
| 25_F | 30_A | 1.229 | 0.98 | |
| 20_A | 23_L | 1.217 | 0.98 | |
| 93_K | 105_G | 1.196 | 0.98 | |
| 155_A | 169_C | 1.196 | 0.98 | |
| 89_D | 119_R | 1.186 | 0.98 | |
| 57_A | 61_Q | 1.185 | 0.98 | |
| 34_G | 45_P | 1.169 | 0.97 | |
| 23_L | 27_E | 1.153 | 0.97 | |
| 24_A | 219_A | 1.144 | 0.97 | |
| 46_F | 70_T | 1.143 | 0.97 | |
| 84_R | 98_Q | 1.138 | 0.97 | |
| 38_A | 41_Q | 1.137 | 0.97 | |
| 76_L | 114_T | 1.134 | 0.97 | |
| 100_F | 105_G | 1.13 | 0.97 | |
| 7_N | 33_T | 1.13 | 0.97 | |
| 135_H | 239_V | 1.118 | 0.96 | |
| 94_E | 98_Q | 1.112 | 0.96 | |
| 72_R | 121_Q | 1.108 | 0.96 | |
| 49_E | 62_V | 1.097 | 0.96 | |
| 86_G | 95_D | 1.093 | 0.96 | |
| 108_F | 154_L | 1.091 | 0.96 | |
| 82_I | 102_V | 1.087 | 0.96 | |
| 61_Q | 64_Q | 1.08 | 0.95 | |
| 96_W | 105_G | 1.076 | 0.95 | |
| 9_W | 62_V | 1.074 | 0.95 | |
| 79_A | 129_V | 1.058 | 0.95 | |
| 47_A | 50_V | 1.056 | 0.95 | |
| 129_V | 222_I | 1.054 | 0.95 | |
| 21_T | 77_V | 1.05 | 0.94 | |
| 171_V | 237_D | 1.048 | 0.94 | |
| 54_A | 98_Q | 1.048 | 0.94 | |
| 224_F | 233_I | 1.039 | 0.94 | |
| 87_A | 90_Q | 1.032 | 0.94 | |
| 152_K | 237_D | 1.029 | 0.94 | |
| 25_F | 223_L | 1.024 | 0.93 | |
| 53_V | 106_G | 1.024 | 0.93 | |
| 144_Y | 148_K | 1.022 | 0.93 | |
| 24_A | 216_Q | 1.021 | 0.93 | |
| 46_F | 49_E | 1.02 | 0.93 | |
| 111_F | 154_L | 1.013 | 0.93 | |
| 15_K | 19_Y | 1.011 | 0.93 | |
| 31_K | 46_F | 1.011 | 0.93 | |
| 17_I | 21_T | 1.01 | 0.93 | |
| 20_A | 215_P | 1.005 | 0.93 | |
| 211_K | 217_E | 1.004 | 0.93 | |
| 21_T | 219_A | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1vl8A | 2 | 0.9597 | 100 | 0.052 | Contact Map | 0.782 |
| 2c07A | 1 | 0.9476 | 100 | 0.057 | Contact Map | 0.741 |
| 3lf2A | 4 | 0.996 | 100 | 0.058 | Contact Map | 0.84 |
| 3op4A | 2 | 0.9516 | 100 | 0.058 | Contact Map | 0.767 |
| 4j2hA | 1 | 0.9637 | 100 | 0.059 | Contact Map | 0.742 |
| 4iinA | 4 | 0.9476 | 100 | 0.059 | Contact Map | 0.854 |
| 4egfA | 8 | 0.9597 | 100 | 0.06 | Contact Map | 0.829 |
| 4dqxA | 4 | 0.9798 | 100 | 0.06 | Contact Map | 0.861 |
| 4ag3A | 4 | 0.9516 | 100 | 0.06 | Contact Map | 0.809 |
| 4bnwA | 4 | 0.9516 | 100 | 0.06 | Contact Map | 0.774 |
Sequence Conservation (Image Generated using WebLogo v3)