| UniProt: | P37769 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12361 | ||
| Length: | 253 (246) | ||
| Sequences: | 50985 | ||
| Seq/Len: | 207.26 |
| KDUD
Paralog alert: 0.89 [within 20: 0.48] - ratio of genomes with paralogs Cluster includes: BDCA ENTA FABG FABI FOLM HCAB HDHA IDNO KDUD SRLD UCPA YBBO YCIK YDFG YGCW YGFF YGHA YOHF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 110_D | 118_K | 3.203 | 1.00 | |
| 110_D | 114_N | 2.923 | 1.00 | |
| 163_S | 167_G | 2.79 | 1.00 | |
| 68_K | 71_G | 2.72 | 1.00 | |
| 142_N | 169_T | 2.599 | 1.00 | |
| 80_V | 130_H | 2.335 | 1.00 | |
| 13_A | 88_I | 2.313 | 1.00 | |
| 139_K | 182_N | 2.31 | 1.00 | |
| 24_Q | 28_L | 2.292 | 1.00 | |
| 73_P | 126_A | 2.251 | 1.00 | |
| 124_S | 172_M | 2.199 | 1.00 | |
| 187_A | 243_T | 2.162 | 1.00 | |
| 132_I | 179_H | 2.145 | 1.00 | |
| 144_A | 166_M | 2.144 | 1.00 | |
| 192_A | 220_L | 2.122 | 1.00 | |
| 29_G | 226_G | 2.075 | 1.00 | |
| 91_N | 142_N | 2.02 | 1.00 | |
| 114_N | 118_K | 2.002 | 1.00 | |
| 88_I | 232_A | 1.973 | 1.00 | |
| 36_D | 58_R | 1.927 | 1.00 | |
| 69_I | 106_E | 1.926 | 1.00 | |
| 128_A | 176_W | 1.903 | 1.00 | |
| 76_L | 127_A | 1.892 | 1.00 | |
| 29_G | 229_V | 1.866 | 1.00 | |
| 40_I | 64_A | 1.847 | 1.00 | |
| 12_V | 36_D | 1.828 | 1.00 | |
| 226_G | 235_A | 1.82 | 1.00 | |
| 29_G | 33_A | 1.819 | 1.00 | |
| 242_Y | 245_A | 1.793 | 1.00 | |
| 28_L | 51_Q | 1.751 | 1.00 | |
| 22_L | 191_M | 1.725 | 1.00 | |
| 120_V | 165_V | 1.72 | 1.00 | |
| 26_M | 228_I | 1.707 | 1.00 | |
| 116_N | 161_S | 1.704 | 1.00 | |
| 169_T | 185_A | 1.691 | 1.00 | |
| 24_Q | 48_T | 1.687 | 1.00 | |
| 24_Q | 51_Q | 1.684 | 1.00 | |
| 78_R | 82_E | 1.679 | 1.00 | |
| 227_P | 244_I | 1.654 | 1.00 | |
| 19_D | 41_N | 1.651 | 1.00 | |
| 18_C | 39_G | 1.62 | 1.00 | |
| 38_V | 83_F | 1.589 | 1.00 | |
| 60_L | 82_E | 1.584 | 1.00 | |
| 117_I | 164_G | 1.573 | 1.00 | |
| 33_A | 229_V | 1.57 | 1.00 | |
| 30_L | 232_A | 1.566 | 1.00 | |
| 77_D | 81_A | 1.564 | 1.00 | |
| 45_P | 61_S | 1.551 | 1.00 | |
| 38_V | 79_A | 1.543 | 1.00 | |
| 40_I | 75_L | 1.535 | 1.00 | |
| 29_G | 32_Q | 1.522 | 1.00 | |
| 113_M | 117_I | 1.506 | 1.00 | |
| 74_A | 78_R | 1.503 | 1.00 | |
| 219_G | 238_Y | 1.481 | 1.00 | |
| 139_K | 184_N | 1.478 | 1.00 | |
| 12_V | 85_H | 1.472 | 1.00 | |
| 64_A | 71_G | 1.466 | 1.00 | |
| 35_C | 88_I | 1.454 | 1.00 | |
| 73_P | 77_D | 1.45 | 1.00 | |
| 105_S | 108_D | 1.444 | 1.00 | |
| 90_V | 143_I | 1.434 | 1.00 | |
| 13_A | 30_L | 1.417 | 1.00 | |
| 89_L | 123_M | 1.41 | 1.00 | |
| 78_R | 81_A | 1.406 | 0.99 | |
| 106_E | 122_F | 1.4 | 0.99 | |
| 46_T | 50_E | 1.372 | 0.99 | |
| 62_L | 78_R | 1.332 | 0.99 | |
| 20_T | 194_N | 1.328 | 0.99 | |
| 64_A | 75_L | 1.328 | 0.99 | |
| 49_I | 53_T | 1.327 | 0.99 | |
| 72_I | 123_M | 1.326 | 0.99 | |
| 69_I | 122_F | 1.322 | 0.99 | |
| 10_G | 35_C | 1.295 | 0.99 | |
| 71_G | 74_A | 1.286 | 0.99 | |
| 69_I | 73_P | 1.284 | 0.99 | |
| 144_A | 185_A | 1.275 | 0.99 | |
| 169_T | 183_V | 1.261 | 0.99 | |
| 49_I | 61_S | 1.255 | 0.99 | |
| 91_N | 124_S | 1.254 | 0.99 | |
| 118_K | 122_F | 1.253 | 0.99 | |
| 124_S | 140_I | 1.244 | 0.98 | |
| 186_I | 228_I | 1.241 | 0.98 | |
| 191_M | 219_G | 1.24 | 0.98 | |
| 30_L | 35_C | 1.239 | 0.98 | |
| 13_A | 35_C | 1.239 | 0.98 | |
| 25_G | 28_L | 1.23 | 0.98 | |
| 27_A | 39_G | 1.23 | 0.98 | |
| 130_H | 134_Q | 1.224 | 0.98 | |
| 227_P | 246_V | 1.224 | 0.98 | |
| 36_D | 57_R | 1.223 | 0.98 | |
| 8_L | 35_C | 1.211 | 0.98 | |
| 25_G | 222_S | 1.207 | 0.98 | |
| 12_V | 38_V | 1.203 | 0.98 | |
| 50_E | 54_A | 1.196 | 0.98 | |
| 28_L | 32_Q | 1.169 | 0.97 | |
| 86_I | 127_A | 1.166 | 0.97 | |
| 172_M | 183_V | 1.145 | 0.97 | |
| 50_E | 53_T | 1.144 | 0.97 | |
| 70_D | 74_A | 1.139 | 0.97 | |
| 29_G | 225_M | 1.132 | 0.97 | |
| 97_R | 111_D | 1.126 | 0.97 | |
| 60_L | 83_F | 1.125 | 0.97 | |
| 89_L | 127_A | 1.12 | 0.96 | |
| 20_T | 44_E | 1.119 | 0.96 | |
| 149_F | 245_A | 1.109 | 0.96 | |
| 113_M | 118_K | 1.105 | 0.96 | |
| 106_E | 118_K | 1.104 | 0.96 | |
| 74_A | 77_D | 1.092 | 0.96 | |
| 102_L | 132_I | 1.091 | 0.96 | |
| 32_Q | 55_L | 1.084 | 0.96 | |
| 95_L | 115_L | 1.076 | 0.95 | |
| 46_T | 49_I | 1.076 | 0.95 | |
| 92_N | 143_I | 1.075 | 0.95 | |
| 100_D | 103_E | 1.074 | 0.95 | |
| 62_L | 75_L | 1.072 | 0.95 | |
| 121_F | 168_V | 1.069 | 0.95 | |
| 107_K | 111_D | 1.067 | 0.95 | |
| 158_Y | 162_K | 1.064 | 0.95 | |
| 67_R | 111_D | 1.061 | 0.95 | |
| 143_I | 228_I | 1.059 | 0.95 | |
| 185_A | 243_T | 1.054 | 0.95 | |
| 99_E | 108_D | 1.046 | 0.94 | |
| 14_V | 75_L | 1.036 | 0.94 | |
| 85_H | 134_Q | 1.035 | 0.94 | |
| 166_M | 243_T | 1.03 | 0.94 | |
| 120_V | 142_N | 1.025 | 0.93 | |
| 36_D | 60_L | 1.022 | 0.93 | |
| 29_G | 222_S | 1.021 | 0.93 | |
| 109_W | 118_K | 1.019 | 0.93 | |
| 26_M | 225_M | 1.014 | 0.93 | |
| 11_K | 87_D | 1.012 | 0.93 | |
| 30_L | 229_V | 1.005 | 0.93 | |
| 124_S | 168_V | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4j2hA | 1 | 0.996 | 100 | 0.073 | Contact Map | 0.742 |
| 4g81D | 4 | 0.996 | 100 | 0.074 | Contact Map | 0.809 |
| 4iboA | 4 | 0.996 | 100 | 0.077 | Contact Map | 0.837 |
| 1vl8A | 2 | 0.996 | 100 | 0.082 | Contact Map | 0.784 |
| 3cxtA | 1 | 0.996 | 100 | 0.083 | Contact Map | 0.686 |
| 4egfA | 8 | 1 | 100 | 0.084 | Contact Map | 0.804 |
| 3v8bA | 4 | 0.996 | 100 | 0.084 | Contact Map | 0.829 |
| 3lf2A | 4 | 0.9881 | 100 | 0.084 | Contact Map | 0.831 |
| 2zatA | 4 | 0.996 | 100 | 0.084 | Contact Map | 0.838 |
| 2ae2A | 2 | 0.9921 | 100 | 0.086 | Contact Map | 0.741 |
Sequence Conservation (Image Generated using WebLogo v3)