| UniProt: | P77806 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13531 | ||
| Length: | 386 (378) | ||
| Sequences: | 19697 | ||
| Seq/Len: | 52.11 |
| YBDL
Paralog alert: 0.93 [within 20: 0.27] - ratio of genomes with paralogs Cluster includes: AAT ALAA ALAC ARNB AVTA CSDA HIS8 ISCS MALY RFFA SERC SUFS TYRB YBDL YDCR YJIR |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 53_A | 57_A | 3.089 | 1.00 | |
| 157_A | 194_G | 2.98 | 1.00 | |
| 296_R | 300_D | 2.831 | 1.00 | |
| 117_E | 138_I | 2.815 | 1.00 | |
| 182_Q | 186_A | 2.803 | 1.00 | |
| 97_T | 103_A | 2.783 | 1.00 | |
| 297_Q | 373_E | 2.671 | 1.00 | |
| 81_E | 87_Q | 2.638 | 1.00 | |
| 312_E | 325_D | 2.55 | 1.00 | |
| 46_R | 50_E | 2.522 | 1.00 | |
| 116_D | 165_R | 2.459 | 1.00 | |
| 340_W | 344_E | 2.452 | 1.00 | |
| 112_V | 137_G | 2.33 | 1.00 | |
| 250_A | 255_S | 2.299 | 1.00 | |
| 75_A | 282_R | 2.293 | 1.00 | |
| 378_A | 382_R | 2.285 | 1.00 | |
| 345_H | 385_Q | 2.19 | 1.00 | |
| 181_Q | 184_D | 2.162 | 1.00 | |
| 245_V | 277_L | 2.157 | 1.00 | |
| 301_I | 377_L | 2.145 | 1.00 | |
| 186_A | 190_Q | 2.144 | 1.00 | |
| 50_E | 54_H | 2.139 | 1.00 | |
| 333_D | 336_E | 2.084 | 1.00 | |
| 71_A | 278_A | 2.084 | 1.00 | |
| 378_A | 381_E | 2.042 | 1.00 | |
| 74_E | 78_Q | 1.998 | 1.00 | |
| 105_Y | 109_T | 1.99 | 1.00 | |
| 74_E | 90_A | 1.885 | 1.00 | |
| 300_D | 304_N | 1.874 | 1.00 | |
| 117_E | 140_K | 1.866 | 1.00 | |
| 192_I | 199_V | 1.862 | 1.00 | |
| 303_V | 307_N | 1.851 | 1.00 | |
| 304_N | 308_E | 1.842 | 1.00 | |
| 305_A | 381_E | 1.832 | 1.00 | |
| 200_I | 231_V | 1.823 | 1.00 | |
| 303_V | 315_P | 1.82 | 1.00 | |
| 150_R | 184_D | 1.819 | 1.00 | |
| 154_Q | 187_A | 1.816 | 1.00 | |
| 166_L | 200_I | 1.798 | 1.00 | |
| 305_A | 308_E | 1.779 | 1.00 | |
| 183_A | 186_A | 1.766 | 1.00 | |
| 305_A | 380_A | 1.766 | 1.00 | |
| 122_D | 141_R | 1.751 | 1.00 | |
| 70_Q | 74_E | 1.748 | 1.00 | |
| 157_A | 187_A | 1.747 | 1.00 | |
| 270_N | 273_A | 1.746 | 1.00 | |
| 132_I | 137_G | 1.737 | 1.00 | |
| 82_R | 285_P | 1.733 | 1.00 | |
| 196_E | 227_R | 1.718 | 1.00 | |
| 204_V | 233_S | 1.715 | 1.00 | |
| 75_A | 78_Q | 1.699 | 1.00 | |
| 78_Q | 282_R | 1.689 | 1.00 | |
| 100_A | 231_V | 1.686 | 1.00 | |
| 152_D | 155_E | 1.666 | 1.00 | |
| 301_I | 373_E | 1.651 | 1.00 | |
| 107_A | 200_I | 1.651 | 1.00 | |
| 187_A | 190_Q | 1.645 | 1.00 | |
| 155_E | 159_L | 1.642 | 1.00 | |
| 155_E | 158_A | 1.639 | 1.00 | |
| 54_H | 279_D | 1.638 | 1.00 | |
| 248_C | 258_I | 1.635 | 1.00 | |
| 301_I | 305_A | 1.63 | 1.00 | |
| 77_A | 90_A | 1.622 | 1.00 | |
| 107_A | 229_V | 1.62 | 1.00 | |
| 10_S | 113_R | 1.606 | 1.00 | |
| 307_N | 313_I | 1.603 | 1.00 | |
| 117_E | 161_S | 1.581 | 1.00 | |
| 349_A | 365_I | 1.573 | 1.00 | |
| 76_I | 247_Y | 1.555 | 1.00 | |
| 35_L | 379_A | 1.553 | 1.00 | |
| 129_A | 133_A | 1.551 | 1.00 | |
| 88_P | 249_V | 1.529 | 1.00 | |
| 49_Q | 53_A | 1.529 | 1.00 | |
| 118_V | 132_I | 1.528 | 1.00 | |
| 145_Q | 184_D | 1.521 | 1.00 | |
| 345_H | 382_R | 1.51 | 1.00 | |
| 289_L | 293_D | 1.504 | 1.00 | |
| 372_K | 375_T | 1.498 | 1.00 | |
| 339_Q | 343_Q | 1.493 | 1.00 | |
| 117_E | 164_T | 1.477 | 1.00 | |
| 303_V | 322_L | 1.47 | 1.00 | |
| 336_E | 340_W | 1.458 | 1.00 | |
| 160_L | 191_A | 1.452 | 1.00 | |
| 71_A | 282_R | 1.451 | 1.00 | |
| 192_I | 197_I | 1.446 | 1.00 | |
| 302_L | 322_L | 1.437 | 1.00 | |
| 76_I | 96_V | 1.429 | 1.00 | |
| 117_E | 163_R | 1.425 | 1.00 | |
| 93_D | 252_A | 1.424 | 1.00 | |
| 50_E | 53_A | 1.424 | 1.00 | |
| 153_W | 191_A | 1.421 | 1.00 | |
| 157_A | 195_H | 1.418 | 1.00 | |
| 305_A | 384_R | 1.414 | 1.00 | |
| 182_Q | 216_A | 1.405 | 0.99 | |
| 51_R | 279_D | 1.403 | 0.99 | |
| 190_Q | 194_G | 1.402 | 0.99 | |
| 190_Q | 193_A | 1.398 | 0.99 | |
| 75_A | 278_A | 1.396 | 0.99 | |
| 334_D | 353_S | 1.386 | 0.99 | |
| 80_T | 249_V | 1.382 | 0.99 | |
| 77_A | 94_I | 1.374 | 0.99 | |
| 182_Q | 221_H | 1.372 | 0.99 | |
| 108_I | 168_I | 1.357 | 0.99 | |
| 69_V | 275_L | 1.356 | 0.99 | |
| 289_L | 292_P | 1.353 | 0.99 | |
| 229_V | 248_C | 1.351 | 0.99 | |
| 381_E | 385_Q | 1.348 | 0.99 | |
| 305_A | 309_S | 1.346 | 0.99 | |
| 91_D | 252_A | 1.342 | 0.99 | |
| 338_C | 349_A | 1.339 | 0.99 | |
| 78_Q | 82_R | 1.328 | 0.99 | |
| 122_D | 143_A | 1.319 | 0.99 | |
| 184_D | 187_A | 1.316 | 0.99 | |
| 324_V | 367_L | 1.3 | 0.99 | |
| 108_I | 132_I | 1.29 | 0.99 | |
| 302_L | 380_A | 1.286 | 0.99 | |
| 308_E | 384_R | 1.284 | 0.99 | |
| 153_W | 187_A | 1.279 | 0.99 | |
| 303_V | 313_I | 1.274 | 0.99 | |
| 129_A | 141_R | 1.273 | 0.99 | |
| 336_E | 339_Q | 1.271 | 0.99 | |
| 229_V | 250_A | 1.269 | 0.99 | |
| 120_C | 139_V | 1.266 | 0.99 | |
| 67_T | 73_R | 1.265 | 0.99 | |
| 118_V | 166_L | 1.264 | 0.99 | |
| 95_T | 255_S | 1.262 | 0.99 | |
| 73_R | 77_A | 1.257 | 0.99 | |
| 76_I | 94_I | 1.247 | 0.99 | |
| 52_L | 276_A | 1.247 | 0.99 | |
| 341_L | 383_L | 1.245 | 0.98 | |
| 307_N | 315_P | 1.242 | 0.98 | |
| 102_E | 262_H | 1.238 | 0.98 | |
| 54_H | 58_Q | 1.234 | 0.98 | |
| 191_A | 195_H | 1.233 | 0.98 | |
| 167_V | 197_I | 1.228 | 0.98 | |
| 323_L | 352_L | 1.224 | 0.98 | |
| 293_D | 296_R | 1.222 | 0.98 | |
| 305_A | 377_L | 1.22 | 0.98 | |
| 46_R | 49_Q | 1.214 | 0.98 | |
| 119_I | 164_T | 1.212 | 0.98 | |
| 157_A | 191_A | 1.21 | 0.98 | |
| 294_F | 373_E | 1.205 | 0.98 | |
| 108_I | 112_V | 1.197 | 0.98 | |
| 183_A | 187_A | 1.19 | 0.98 | |
| 143_A | 155_E | 1.19 | 0.98 | |
| 193_A | 223_Q | 1.186 | 0.98 | |
| 377_L | 381_E | 1.186 | 0.98 | |
| 234_F | 277_L | 1.183 | 0.98 | |
| 67_T | 259_R | 1.181 | 0.98 | |
| 80_T | 247_Y | 1.18 | 0.98 | |
| 112_V | 118_V | 1.172 | 0.98 | |
| 299_R | 303_V | 1.169 | 0.97 | |
| 89_D | 252_A | 1.167 | 0.97 | |
| 191_A | 197_I | 1.166 | 0.97 | |
| 294_F | 297_Q | 1.163 | 0.97 | |
| 145_Q | 152_D | 1.159 | 0.97 | |
| 304_N | 307_N | 1.158 | 0.97 | |
| 325_D | 364_L | 1.155 | 0.97 | |
| 373_E | 377_L | 1.15 | 0.97 | |
| 182_Q | 220_A | 1.15 | 0.97 | |
| 333_D | 362_H | 1.149 | 0.97 | |
| 257_E | 260_K | 1.148 | 0.97 | |
| 111_L | 198_F | 1.142 | 0.97 | |
| 161_S | 164_T | 1.139 | 0.97 | |
| 109_T | 135_S | 1.137 | 0.97 | |
| 232_S | 247_Y | 1.135 | 0.97 | |
| 98_A | 102_E | 1.133 | 0.97 | |
| 169_L | 188_L | 1.133 | 0.97 | |
| 293_D | 297_Q | 1.133 | 0.97 | |
| 103_A | 248_C | 1.132 | 0.97 | |
| 71_A | 275_L | 1.118 | 0.96 | |
| 199_V | 218_V | 1.113 | 0.96 | |
| 49_Q | 57_A | 1.101 | 0.96 | |
| 256_A | 260_K | 1.101 | 0.96 | |
| 347_V | 383_L | 1.099 | 0.96 | |
| 160_L | 197_I | 1.098 | 0.96 | |
| 94_I | 249_V | 1.095 | 0.96 | |
| 72_L | 96_V | 1.088 | 0.96 | |
| 154_Q | 158_A | 1.085 | 0.96 | |
| 186_A | 221_H | 1.083 | 0.96 | |
| 337_F | 365_I | 1.079 | 0.95 | |
| 189_W | 199_V | 1.075 | 0.95 | |
| 111_L | 166_L | 1.074 | 0.95 | |
| 71_A | 74_E | 1.073 | 0.95 | |
| 198_F | 229_V | 1.073 | 0.95 | |
| 119_I | 142_M | 1.072 | 0.95 | |
| 40_P | 295_Y | 1.071 | 0.95 | |
| 186_A | 224_L | 1.071 | 0.95 | |
| 298_K | 301_I | 1.068 | 0.95 | |
| 304_N | 377_L | 1.059 | 0.95 | |
| 110_A | 261_V | 1.057 | 0.95 | |
| 279_D | 283_A | 1.057 | 0.95 | |
| 114_N | 136_G | 1.057 | 0.95 | |
| 211_S | 317_E | 1.057 | 0.95 | |
| 77_A | 89_D | 1.051 | 0.94 | |
| 10_S | 13_P | 1.045 | 0.94 | |
| 157_A | 161_S | 1.044 | 0.94 | |
| 341_L | 349_A | 1.044 | 0.94 | |
| 299_R | 369_F | 1.041 | 0.94 | |
| 51_R | 55_H | 1.036 | 0.94 | |
| 300_D | 315_P | 1.036 | 0.94 | |
| 52_L | 56_V | 1.035 | 0.94 | |
| 103_A | 231_V | 1.033 | 0.94 | |
| 286_E | 290_A | 1.033 | 0.94 | |
| 302_L | 376_L | 1.031 | 0.94 | |
| 375_T | 378_A | 1.03 | 0.94 | |
| 262_H | 266_T | 1.028 | 0.94 | |
| 119_I | 167_V | 1.024 | 0.93 | |
| 70_Q | 90_A | 1.02 | 0.93 | |
| 93_D | 225_R | 1.017 | 0.93 | |
| 124_S | 170_N | 1.006 | 0.93 | |
| 89_D | 93_D | 1.005 | 0.93 | |
| 189_W | 228_A | 1.005 | 0.93 | |
| 279_D | 282_R | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1u08A | 2 | 0.9974 | 100 | 0.263 | Contact Map | 0.71 |
| 1yizA | 2 | 0.9974 | 100 | 0.28 | Contact Map | 0.741 |
| 3fvsA | 2 | 0.9922 | 100 | 0.283 | Contact Map | 0.72 |
| 1vp4A | 2 | 0.9793 | 100 | 0.284 | Contact Map | 0.797 |
| 3e2yA | 2 | 0.9793 | 100 | 0.285 | Contact Map | 0.732 |
| 2o0rA | 2 | 0.987 | 100 | 0.288 | Contact Map | 0.711 |
| 4je5A | 3 | 0.9793 | 100 | 0.288 | Contact Map | 0.718 |
| 2x5dA | 4 | 0.9948 | 100 | 0.289 | Contact Map | 0.768 |
| 1gd9A | 2 | 0.9793 | 100 | 0.293 | Contact Map | 0.793 |
| 1j32A | 2 | 0.9689 | 100 | 0.297 | Contact Map | 0.793 |
Sequence Conservation (Image Generated using WebLogo v3)