| UniProt: | P0AAF1 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10753 | ||
| Length: | 439 (428) | ||
| Sequences: | 11026 | ||
| Seq/Len: | 25.76 |
| POTE
Paralog alert: 0.82 [within 20: 0.39] - ratio of genomes with paralogs Cluster includes: ADIC ANSP ARCD AROP CADB CYCA FRLA GABP GADC LYSP MMUP PHEP PLAP POTE PROY PUUP YBAT YCAM YGJI YIFK YJEH YJEM |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 312_I | 324_Q | 4.215 | 1.00 | |
| 136_T | 330_V | 3.506 | 1.00 | |
| 168_G | 244_V | 3.213 | 1.00 | |
| 304_S | 314_S | 3.091 | 1.00 | |
| 315_R | 324_Q | 3.029 | 1.00 | |
| 10_G | 217_E | 2.972 | 1.00 | |
| 221_R | 225_I | 2.943 | 1.00 | |
| 49_A | 235_A | 2.92 | 1.00 | |
| 373_I | 377_V | 2.904 | 1.00 | |
| 218_N | 221_R | 2.851 | 1.00 | |
| 307_G | 311_K | 2.514 | 1.00 | |
| 129_I | 338_L | 2.505 | 1.00 | |
| 365_I | 396_A | 2.457 | 1.00 | |
| 253_E | 267_Q | 2.434 | 1.00 | |
| 327_L | 331_I | 2.425 | 1.00 | |
| 368_M | 395_G | 2.396 | 1.00 | |
| 216_V | 222_N | 2.373 | 1.00 | |
| 312_I | 315_R | 2.365 | 1.00 | |
| 301_K | 305_D | 2.349 | 1.00 | |
| 15_T | 229_G | 2.328 | 1.00 | |
| 89_N | 303_S | 2.308 | 1.00 | |
| 317_T | 323_V | 2.307 | 1.00 | |
| 11_V | 229_G | 2.288 | 1.00 | |
| 393_F | 397_M | 2.225 | 1.00 | |
| 166_I | 170_F | 2.192 | 1.00 | |
| 73_G | 306_E | 2.138 | 1.00 | |
| 272_E | 276_V | 2.13 | 1.00 | |
| 58_A | 368_M | 2.117 | 1.00 | |
| 11_V | 222_N | 2.085 | 1.00 | |
| 214_D | 305_D | 2.071 | 1.00 | |
| 61_K | 375_Q | 2.068 | 1.00 | |
| 215_V | 298_Q | 2.044 | 1.00 | |
| 313_F | 328_T | 1.999 | 1.00 | |
| 80_F | 369_A | 1.998 | 1.00 | |
| 77_E | 82_K | 1.966 | 1.00 | |
| 11_V | 15_T | 1.948 | 1.00 | |
| 10_G | 13_Q | 1.947 | 1.00 | |
| 80_F | 373_I | 1.943 | 1.00 | |
| 136_T | 326_M | 1.936 | 1.00 | |
| 14_L | 216_V | 1.923 | 1.00 | |
| 77_E | 85_N | 1.915 | 1.00 | |
| 225_I | 229_G | 1.91 | 1.00 | |
| 5_K | 316_V | 1.892 | 1.00 | |
| 144_R | 148_Q | 1.875 | 1.00 | |
| 50_V | 54_A | 1.872 | 1.00 | |
| 140_F | 323_V | 1.867 | 1.00 | |
| 250_P | 253_E | 1.837 | 1.00 | |
| 373_I | 376_K | 1.836 | 1.00 | |
| 93_G | 329_I | 1.829 | 1.00 | |
| 140_F | 327_L | 1.823 | 1.00 | |
| 129_I | 334_S | 1.822 | 1.00 | |
| 137_V | 141_G | 1.767 | 1.00 | |
| 158_I | 162_V | 1.746 | 1.00 | |
| 155_W | 159_I | 1.732 | 1.00 | |
| 50_V | 394_V | 1.714 | 1.00 | |
| 390_F | 394_V | 1.703 | 1.00 | |
| 128_T | 337_A | 1.697 | 1.00 | |
| 397_M | 401_Y | 1.666 | 1.00 | |
| 44_S | 195_S | 1.658 | 1.00 | |
| 13_Q | 151_S | 1.652 | 1.00 | |
| 90_Y | 421_G | 1.651 | 1.00 | |
| 88_A | 366_L | 1.645 | 1.00 | |
| 423_T | 427_L | 1.628 | 1.00 | |
| 133_W | 334_S | 1.628 | 1.00 | |
| 218_N | 225_I | 1.616 | 1.00 | |
| 415_S | 419_F | 1.612 | 1.00 | |
| 389_N | 393_F | 1.607 | 1.00 | |
| 228_L | 232_L | 1.598 | 1.00 | |
| 132_L | 333_Q | 1.585 | 1.00 | |
| 232_L | 236_V | 1.572 | 1.00 | |
| 76_A | 88_A | 1.565 | 1.00 | |
| 15_T | 233_G | 1.554 | 1.00 | |
| 263_L | 266_A | 1.549 | 1.00 | |
| 263_L | 267_Q | 1.549 | 1.00 | |
| 300_F | 325_G | 1.545 | 1.00 | |
| 81_G | 84_G | 1.544 | 1.00 | |
| 219_P | 224_P | 1.544 | 1.00 | |
| 218_N | 222_N | 1.52 | 1.00 | |
| 9_M | 13_Q | 1.517 | 1.00 | |
| 317_T | 321_A | 1.517 | 1.00 | |
| 296_I | 329_I | 1.504 | 1.00 | |
| 324_Q | 328_T | 1.501 | 1.00 | |
| 139_N | 290_L | 1.481 | 1.00 | |
| 388_A | 392_A | 1.476 | 1.00 | |
| 22_M | 234_A | 1.463 | 1.00 | |
| 46_L | 239_I | 1.462 | 1.00 | |
| 319_V | 323_V | 1.461 | 1.00 | |
| 212_N | 294_F | 1.458 | 1.00 | |
| 275_K | 279_A | 1.452 | 1.00 | |
| 311_K | 314_S | 1.45 | 1.00 | |
| 76_A | 366_L | 1.449 | 1.00 | |
| 133_W | 330_V | 1.432 | 1.00 | |
| 297_A | 326_M | 1.432 | 1.00 | |
| 387_V | 391_V | 1.403 | 0.99 | |
| 56_A | 231_T | 1.403 | 0.99 | |
| 80_F | 84_G | 1.396 | 0.99 | |
| 412_L | 416_I | 1.395 | 0.99 | |
| 54_A | 394_V | 1.39 | 0.99 | |
| 389_N | 392_A | 1.383 | 0.99 | |
| 9_M | 147_G | 1.38 | 0.99 | |
| 331_I | 335_G | 1.379 | 0.99 | |
| 141_G | 319_V | 1.374 | 0.99 | |
| 48_T | 199_T | 1.369 | 0.99 | |
| 136_T | 327_L | 1.366 | 0.99 | |
| 11_V | 225_I | 1.363 | 0.99 | |
| 58_A | 392_A | 1.359 | 0.99 | |
| 19_M | 233_G | 1.349 | 0.99 | |
| 369_A | 373_I | 1.343 | 0.99 | |
| 159_I | 163_G | 1.339 | 0.99 | |
| 104_A | 289_L | 1.332 | 0.99 | |
| 423_T | 426_G | 1.329 | 0.99 | |
| 135_C | 289_L | 1.321 | 0.99 | |
| 66_S | 78_Y | 1.318 | 0.99 | |
| 395_G | 399_S | 1.315 | 0.99 | |
| 55_L | 368_M | 1.314 | 0.99 | |
| 257_S | 263_L | 1.303 | 0.99 | |
| 18_T | 230_G | 1.302 | 0.99 | |
| 63_G | 75_Y | 1.294 | 0.99 | |
| 222_N | 225_I | 1.29 | 0.99 | |
| 165_C | 240_V | 1.287 | 0.99 | |
| 266_A | 271_P | 1.284 | 0.99 | |
| 160_P | 280_L | 1.282 | 0.99 | |
| 86_F | 90_Y | 1.28 | 0.99 | |
| 125_G | 129_I | 1.279 | 0.99 | |
| 311_K | 315_R | 1.273 | 0.99 | |
| 301_K | 316_V | 1.269 | 0.99 | |
| 132_L | 330_V | 1.269 | 0.99 | |
| 316_V | 320_D | 1.268 | 0.99 | |
| 387_V | 390_F | 1.258 | 0.99 | |
| 9_M | 14_L | 1.257 | 0.99 | |
| 300_F | 309_F | 1.255 | 0.99 | |
| 240_V | 244_V | 1.255 | 0.99 | |
| 315_R | 323_V | 1.253 | 0.99 | |
| 6_S | 320_D | 1.253 | 0.99 | |
| 56_A | 227_V | 1.248 | 0.99 | |
| 51_G | 398_Y | 1.246 | 0.98 | |
| 90_Y | 309_F | 1.245 | 0.98 | |
| 172_F | 247_G | 1.243 | 0.98 | |
| 419_F | 423_T | 1.243 | 0.98 | |
| 305_D | 314_S | 1.242 | 0.98 | |
| 111_G | 127_A | 1.24 | 0.98 | |
| 396_A | 400_F | 1.238 | 0.98 | |
| 266_A | 274_G | 1.235 | 0.98 | |
| 129_I | 133_W | 1.233 | 0.98 | |
| 365_I | 369_A | 1.215 | 0.98 | |
| 136_T | 140_F | 1.214 | 0.98 | |
| 79_A | 370_A | 1.211 | 0.98 | |
| 69_S | 214_D | 1.21 | 0.98 | |
| 269_F | 273_V | 1.195 | 0.98 | |
| 270_T | 273_V | 1.192 | 0.98 | |
| 68_K | 74_G | 1.187 | 0.98 | |
| 143_A | 294_F | 1.186 | 0.98 | |
| 204_L | 360_N | 1.183 | 0.98 | |
| 126_L | 130_G | 1.181 | 0.98 | |
| 104_A | 132_L | 1.179 | 0.98 | |
| 390_F | 393_F | 1.175 | 0.98 | |
| 140_F | 321_A | 1.174 | 0.98 | |
| 42_I | 243_N | 1.174 | 0.98 | |
| 34_L | 41_S | 1.167 | 0.97 | |
| 372_V | 393_F | 1.161 | 0.97 | |
| 168_G | 248_I | 1.155 | 0.97 | |
| 49_A | 203_F | 1.147 | 0.97 | |
| 369_A | 396_A | 1.139 | 0.97 | |
| 83_S | 422_W | 1.137 | 0.97 | |
| 70_G | 73_G | 1.135 | 0.97 | |
| 413_Y | 416_I | 1.132 | 0.97 | |
| 422_W | 426_G | 1.132 | 0.97 | |
| 8_K | 144_R | 1.132 | 0.97 | |
| 12_V | 16_I | 1.131 | 0.97 | |
| 140_F | 317_T | 1.124 | 0.97 | |
| 137_V | 140_F | 1.119 | 0.96 | |
| 12_V | 148_Q | 1.113 | 0.96 | |
| 43_I | 192_V | 1.11 | 0.96 | |
| 247_G | 250_P | 1.109 | 0.96 | |
| 324_Q | 327_L | 1.107 | 0.96 | |
| 169_W | 244_V | 1.103 | 0.96 | |
| 180_S | 183_P | 1.102 | 0.96 | |
| 61_K | 64_M | 1.1 | 0.96 | |
| 46_L | 50_V | 1.098 | 0.96 | |
| 74_G | 78_Y | 1.091 | 0.96 | |
| 236_V | 240_V | 1.089 | 0.96 | |
| 13_Q | 148_Q | 1.088 | 0.96 | |
| 107_A | 282_V | 1.084 | 0.96 | |
| 76_A | 370_A | 1.082 | 0.96 | |
| 392_A | 395_G | 1.076 | 0.95 | |
| 73_G | 302_S | 1.068 | 0.95 | |
| 59_F | 72_M | 1.064 | 0.95 | |
| 217_E | 222_N | 1.061 | 0.95 | |
| 317_T | 320_D | 1.059 | 0.95 | |
| 220_E | 382_P | 1.058 | 0.95 | |
| 149_I | 153_T | 1.056 | 0.95 | |
| 8_K | 217_E | 1.053 | 0.95 | |
| 358_V | 414_G | 1.047 | 0.94 | |
| 18_T | 209_A | 1.044 | 0.94 | |
| 150_S | 290_L | 1.042 | 0.94 | |
| 14_L | 226_A | 1.041 | 0.94 | |
| 43_I | 46_L | 1.036 | 0.94 | |
| 53_M | 57_W | 1.033 | 0.94 | |
| 76_A | 84_G | 1.033 | 0.94 | |
| 207_E | 211_A | 1.032 | 0.94 | |
| 153_T | 287_G | 1.031 | 0.94 | |
| 293_Q | 297_A | 1.028 | 0.94 | |
| 13_Q | 147_G | 1.026 | 0.94 | |
| 416_I | 420_L | 1.024 | 0.93 | |
| 57_W | 228_L | 1.022 | 0.93 | |
| 10_G | 144_R | 1.02 | 0.93 | |
| 164_L | 265_F | 1.02 | 0.93 | |
| 416_I | 419_F | 1.018 | 0.93 | |
| 213_T | 223_V | 1.016 | 0.93 | |
| 120_S | 123_Q | 1.013 | 0.93 | |
| 17_L | 212_N | 1.01 | 0.93 | |
| 62_C | 371_L | 1.008 | 0.93 | |
| 173_S | 176_L | 1.005 | 0.93 | |
| 93_G | 300_F | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3l1lA | 1 | 0.9954 | 100 | 0.272 | Contact Map | 0.688 |
| 3giaA | 1 | 0.9636 | 100 | 0.311 | Contact Map | 0.59 |
| 4djkA | 2 | 0.9772 | 100 | 0.344 | Contact Map | 0.605 |
| 3dh4A | 4 | 0.9544 | 98.1 | 0.889 | Contact Map | 0.417 |
| 2xq2A | 1 | 0.9499 | 97.7 | 0.899 | Contact Map | 0.499 |
| 2jlnA | 1 | 0.8998 | 97.6 | 0.9 | Contact Map | 0.401 |
| 2a65A | 1 | 0.9476 | 95.2 | 0.923 | Contact Map | 0.459 |
| 4m48A | 1 | 0.9567 | 90.3 | 0.936 | Contact Map | 0.394 |
| 2wswA | 1 | 0.8132 | 89.8 | 0.936 | Contact Map | 0.261 |
| 4c7rA | 3 | 0.9134 | 53.7 | 0.954 | Contact Map | 0.347 |
Sequence Conservation (Image Generated using WebLogo v3)