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YBAT - Inner membrane transport protein YbaT
UniProt: P77400 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13248
Length: 430 (421)
Sequences: 10721
Seq/Len: 25.47
YBAT
Paralog alert: 0.82 [within 20: 0.37] - ratio of genomes with paralogs
Cluster includes: ADIC ANSP ARCD AROP CADB CYCA FRLA GABP GADC LYSP MMUP PHEP PLAP POTE PROY PUUP YBAT YCAM YGJI YIFK YJEH YJEM
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
316_L 327_W 4.231 1.00
143_T 333_V 3.517 1.00
175_G 247_V 3.186 1.00
14_G 220_K 3.097 1.00
308_G 318_N 3.033 1.00
54_G 238_T 2.996 1.00
369_R 373_D 2.954 1.00
361_L 385_T 2.952 1.00
224_V 228_R 2.943 1.00
221_D 224_V 2.784 1.00
319_K 327_W 2.685 1.00
311_R 315_K 2.499 1.00
330_I 334_V 2.468 1.00
256_E 271_P 2.372 1.00
305_D 309_S 2.364 1.00
173_I 177_W 2.361 1.00
276_V 280_I 2.36 1.00
219_V 225_I 2.352 1.00
364_F 384_G 2.334 1.00
15_L 232_V 2.31 1.00
19_V 232_V 2.29 1.00
78_I 310_E 2.256 1.00
382_I 386_L 2.234 1.00
136_L 341_A 2.218 1.00
316_L 319_K 2.117 1.00
63_A 364_F 2.106 1.00
66_R 371_R 2.106 1.00
217_D 309_S 2.083 1.00
15_L 225_I 2.082 1.00
14_G 17_N 2.053 1.00
317_M 331_I 2.049 1.00
218_K 302_N 2.037 1.00
85_L 369_R 2.036 1.00
253_S 256_E 1.967 1.00
143_T 329_N 1.931 1.00
85_L 365_V 1.93 1.00
15_L 19_V 1.929 1.00
82_R 87_N 1.923 1.00
147_S 326_T 1.898 1.00
228_R 232_V 1.897 1.00
369_R 372_H 1.893 1.00
99_L 332_V 1.889 1.00
18_V 219_V 1.88 1.00
55_I 59_F 1.877 1.00
162_G 166_M 1.82 1.00
151_H 155_R 1.811 1.00
147_S 330_I 1.796 1.00
49_A 198_C 1.775 1.00
144_L 148_L 1.772 1.00
380_I 384_G 1.77 1.00
55_I 383_V 1.749 1.00
136_L 337_M 1.735 1.00
92_L 307_M 1.71 1.00
165_M 169_L 1.674 1.00
386_L 390_L 1.647 1.00
51_A 242_I 1.642 1.00
140_A 337_M 1.635 1.00
235_G 239_L 1.632 1.00
19_V 236_V 1.629 1.00
17_N 158_V 1.605 1.00
221_D 228_R 1.601 1.00
139_I 336_I 1.597 1.00
411_I 415_L 1.589 1.00
267_Q 270_S 1.588 1.00
419_I 423_V 1.578 1.00
379_P 383_V 1.56 1.00
13_L 17_N 1.56 1.00
222_P 227_P 1.557 1.00
327_W 331_I 1.555 1.00
38_A 46_T 1.551 1.00
221_D 225_I 1.537 1.00
231_L 235_G 1.525 1.00
300_V 332_V 1.505 1.00
304_M 328_G 1.504 1.00
146_N 294_N 1.496 1.00
215_A 298_F 1.491 1.00
301_F 329_N 1.48 1.00
92_L 95_S 1.472 1.00
315_K 318_N 1.462 1.00
135_A 340_T 1.461 1.00
23_I 236_V 1.457 1.00
322_W 326_T 1.457 1.00
166_M 170_L 1.457 1.00
418_L 422_M 1.456 1.00
267_Q 271_P 1.45 1.00
279_V 283_I 1.442 1.00
84_G 366_V 1.441 1.00
45_S 195_F 1.44 1.00
26_M 237_T 1.426 1.00
81_F 362_A 1.426 1.00
148_L 322_W 1.426 1.00
71_Y 83_R 1.415 1.00
110_A 293_I 1.414 1.00
110_A 139_I 1.411 1.00
81_F 91_S 1.401 0.99
61_G 234_I 1.397 0.99
172_I 243_S 1.384 0.99
175_G 251_D 1.382 0.99
381_L 384_G 1.377 0.99
117_A 134_Y 1.377 0.99
15_L 228_R 1.367 0.99
60_S 364_F 1.361 0.99
385_T 389_L 1.355 0.99
22_G 233_A 1.351 0.99
132_L 136_L 1.346 0.99
225_I 228_R 1.342 0.99
176_V 247_V 1.341 0.99
179_L 250_S 1.34 0.99
142_M 293_I 1.334 0.99
270_S 275_H 1.332 0.99
13_L 154_G 1.328 0.99
136_L 140_A 1.325 0.99
143_T 330_I 1.315 0.99
53_G 202_T 1.315 0.99
39_A 46_T 1.311 0.99
167_I 284_G 1.309 0.99
270_S 278_Y 1.307 0.99
304_M 313_L 1.298 0.99
365_V 385_T 1.297 0.99
68_G 80_F 1.292 0.99
79_D 83_R 1.291 0.99
334_V 338_L 1.285 0.99
61_G 230_F 1.278 0.99
140_A 333_V 1.275 0.99
368_I 382_I 1.262 0.99
48_V 195_F 1.26 0.99
315_K 319_K 1.259 0.99
113_F 286_L 1.251 0.99
274_G 277_G 1.249 0.99
74_N 217_D 1.249 0.99
365_V 369_R 1.246 0.98
47_W 246_L 1.238 0.98
106_I 336_I 1.237 0.98
10_N 323_R 1.234 0.98
63_A 381_L 1.231 0.98
408_I 412_G 1.23 0.98
207_A 356_F 1.23 0.98
150_N 298_F 1.228 0.98
143_T 147_S 1.226 0.98
33_A 112_A 1.219 0.98
378_L 382_I 1.218 0.98
139_I 333_V 1.205 0.98
13_L 18_V 1.2 0.98
91_S 362_A 1.197 0.98
133_L 137_G 1.197 0.98
390_L 393_V 1.191 0.98
93_A 417_S 1.188 0.98
309_S 318_N 1.181 0.98
16_W 20_S 1.179 0.98
239_L 243_S 1.173 0.98
415_L 419_I 1.172 0.98
73_S 79_D 1.171 0.98
367_A 381_L 1.169 0.97
108_M 204_L 1.163 0.97
261_A 267_Q 1.156 0.97
54_G 206_Y 1.153 0.97
361_L 365_V 1.148 0.97
192_S 195_F 1.146 0.97
75_G 78_I 1.145 0.97
16_W 155_R 1.14 0.97
147_S 324_Q 1.137 0.97
38_A 42_M 1.135 0.97
319_K 326_T 1.131 0.97
273_L 277_G 1.129 0.97
51_A 55_I 1.127 0.97
93_A 313_L 1.126 0.97
78_I 306_N 1.123 0.97
393_V 397_Y 1.12 0.96
144_L 147_S 1.116 0.96
66_R 69_A 1.114 0.96
31_I 244_L 1.112 0.96
156_L 160_L 1.108 0.96
171_L 175_G 1.107 0.96
378_L 381_L 1.106 0.96
9_G 305_D 1.104 0.96
64_Y 77_I 1.104 0.96
17_N 155_R 1.101 0.96
210_G 214_N 1.089 0.96
327_W 330_I 1.088 0.96
12_P 151_H 1.084 0.96
62_Y 231_L 1.083 0.96
419_I 422_M 1.083 0.96
338_L 341_A 1.076 0.95
384_G 388_M 1.075 0.95
220_K 225_I 1.071 0.95
28_G 241_Y 1.07 0.95
157_E 294_N 1.069 0.95
243_S 247_V 1.06 0.95
22_G 212_M 1.055 0.95
412_G 416_L 1.052 0.95
255_L 259_K 1.048 0.94
368_I 372_H 1.046 0.94
101_T 356_F 1.044 0.94
81_F 366_V 1.039 0.94
297_L 301_F 1.032 0.94
85_L 366_V 1.03 0.94
169_L 173_I 1.024 0.93
351_V 355_T 1.021 0.93
216_A 226_M 1.021 0.93
48_V 51_A 1.02 0.93
409_W 412_G 1.016 0.93
17_N 154_G 1.015 0.93
18_V 229_A 1.014 0.93
145_F 156_L 1.012 0.93
20_S 158_V 1.011 0.93
408_I 411_I 1.009 0.93
412_G 415_L 1.006 0.93
170_L 174_A 1.005 0.93
354_A 410_I 1.005 0.93
140_A 144_L 1.002 0.92
14_G 151_H 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3giaA10.9861000.263Contact Map0.616
3l1lA10.96981000.317Contact Map0.646
4djkA20.98141000.331Contact Map0.571
3dh4A40.941996.80.908Contact Map0.349
2jlnA10.902396.70.909Contact Map0.417
2xq2A10.944295.40.919Contact Map0.432
4m48A10.953586.20.937Contact Map0.363
2wswA10.830281.80.94Contact Map0.26
2a65A10.944267.20.947Contact Map0.4
4ainA30.88634.50.957Contact Map0.327
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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