| UniProt: | P77721 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13482 | ||
| Length: | 252 (251) | ||
| Sequences: | 3501 | ||
| Seq/Len: | 13.95 |
| YDJF
Paralog alert: 0.83 [within 20: 0.11] - ratio of genomes with paralogs Cluster includes: AGAR DEOR FUCR GATR GLPR SGCR SRLR ULAR YCIT YDJF YGBI YIHW |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 108_L | 206_L | 3.58 | 1.00 | |
| 95_T | 168_I | 3.234 | 1.00 | |
| 86_K | 89_P | 3.024 | 1.00 | |
| 169_M | 200_A | 2.758 | 1.00 | |
| 100_D | 193_K | 2.728 | 1.00 | |
| 137_K | 144_E | 2.582 | 1.00 | |
| 13_M | 28_I | 2.211 | 1.00 | |
| 168_I | 204_A | 2.159 | 1.00 | |
| 197_I | 221_A | 2.06 | 1.00 | |
| 204_A | 228_Y | 1.994 | 1.00 | |
| 98_A | 166_V | 1.967 | 1.00 | |
| 110_K | 130_V | 1.917 | 1.00 | |
| 219_Q | 222_D | 1.905 | 1.00 | |
| 87_A | 170_V | 1.877 | 1.00 | |
| 168_I | 202_E | 1.867 | 1.00 | |
| 87_A | 206_L | 1.862 | 1.00 | |
| 121_L | 166_V | 1.842 | 1.00 | |
| 166_V | 196_M | 1.841 | 1.00 | |
| 13_M | 17_D | 1.841 | 1.00 | |
| 25_L | 36_I | 1.819 | 1.00 | |
| 98_A | 196_M | 1.8 | 1.00 | |
| 197_I | 203_V | 1.793 | 1.00 | |
| 209_H | 232_D | 1.782 | 1.00 | |
| 228_Y | 251_V | 1.76 | 1.00 | |
| 92_D | 95_T | 1.756 | 1.00 | |
| 85_R | 111_L | 1.742 | 1.00 | |
| 91_I | 112_L | 1.737 | 1.00 | |
| 235_P | 240_I | 1.735 | 1.00 | |
| 99_A | 105_V | 1.73 | 1.00 | |
| 9_A | 12_Q | 1.73 | 1.00 | |
| 202_E | 228_Y | 1.73 | 1.00 | |
| 81_Q | 107_E | 1.708 | 1.00 | |
| 222_D | 225_H | 1.707 | 1.00 | |
| 93_N | 115_R | 1.702 | 1.00 | |
| 240_I | 244_K | 1.696 | 1.00 | |
| 120_L | 136_I | 1.677 | 1.00 | |
| 141_T | 157_T | 1.673 | 1.00 | |
| 108_L | 170_V | 1.671 | 1.00 | |
| 95_T | 167_D | 1.67 | 1.00 | |
| 93_N | 116_S | 1.666 | 1.00 | |
| 159_E | 162_R | 1.656 | 1.00 | |
| 31_V | 36_I | 1.65 | 1.00 | |
| 88_L | 111_L | 1.624 | 1.00 | |
| 107_E | 110_K | 1.617 | 1.00 | |
| 101_S | 151_S | 1.595 | 1.00 | |
| 162_R | 195_T | 1.59 | 1.00 | |
| 76_F | 210_S | 1.586 | 1.00 | |
| 167_D | 201_T | 1.581 | 1.00 | |
| 84_A | 111_L | 1.581 | 1.00 | |
| 182_A | 205_L | 1.575 | 1.00 | |
| 140_S | 152_L | 1.551 | 1.00 | |
| 76_F | 79_E | 1.544 | 1.00 | |
| 7_I | 46_E | 1.532 | 1.00 | |
| 124_S | 127_A | 1.532 | 1.00 | |
| 40_L | 56_A | 1.53 | 1.00 | |
| 9_A | 13_M | 1.491 | 1.00 | |
| 145_L | 152_L | 1.477 | 1.00 | |
| 11_K | 48_F | 1.459 | 1.00 | |
| 141_T | 160_I | 1.456 | 1.00 | |
| 159_E | 163_R | 1.442 | 1.00 | |
| 170_V | 204_A | 1.423 | 1.00 | |
| 11_K | 14_V | 1.42 | 1.00 | |
| 19_K | 57_V | 1.414 | 1.00 | |
| 203_V | 226_I | 1.397 | 0.99 | |
| 34_E | 38_R | 1.379 | 0.99 | |
| 141_T | 152_L | 1.372 | 0.99 | |
| 17_D | 24_N | 1.365 | 0.99 | |
| 158_K | 191_E | 1.363 | 0.99 | |
| 128_I | 131_L | 1.352 | 0.99 | |
| 195_T | 199_Q | 1.341 | 0.99 | |
| 90_F | 204_A | 1.337 | 0.99 | |
| 8_Q | 12_Q | 1.335 | 0.99 | |
| 195_T | 198_R | 1.33 | 0.99 | |
| 90_F | 230_I | 1.325 | 0.99 | |
| 205_L | 226_I | 1.317 | 0.99 | |
| 13_M | 20_V | 1.316 | 0.99 | |
| 212_F | 229_I | 1.316 | 0.99 | |
| 86_K | 251_V | 1.311 | 0.99 | |
| 126_E | 131_L | 1.298 | 0.99 | |
| 88_L | 108_L | 1.279 | 0.99 | |
| 119_T | 139_V | 1.274 | 0.99 | |
| 125_A | 128_I | 1.273 | 0.99 | |
| 241_A | 245_D | 1.27 | 0.99 | |
| 162_R | 198_R | 1.269 | 0.99 | |
| 84_A | 88_L | 1.266 | 0.99 | |
| 202_E | 227_N | 1.247 | 0.99 | |
| 81_Q | 111_L | 1.245 | 0.98 | |
| 94_K | 117_G | 1.244 | 0.98 | |
| 212_F | 235_P | 1.239 | 0.98 | |
| 236_G | 239_W | 1.237 | 0.98 | |
| 10_I | 25_L | 1.234 | 0.98 | |
| 14_V | 58_L | 1.233 | 0.98 | |
| 182_A | 226_I | 1.233 | 0.98 | |
| 157_T | 192_I | 1.213 | 0.98 | |
| 9_A | 29_F | 1.208 | 0.98 | |
| 128_I | 140_S | 1.207 | 0.98 | |
| 175_G | 183_L | 1.207 | 0.98 | |
| 127_A | 131_L | 1.196 | 0.98 | |
| 173_C | 220_L | 1.185 | 0.98 | |
| 80_K | 103_S | 1.181 | 0.98 | |
| 14_V | 49_L | 1.179 | 0.98 | |
| 77_Y | 107_E | 1.172 | 0.98 | |
| 144_E | 188_A | 1.171 | 0.98 | |
| 88_L | 91_I | 1.169 | 0.97 | |
| 176_L | 212_F | 1.164 | 0.97 | |
| 102_S | 105_V | 1.154 | 0.97 | |
| 22_V | 40_L | 1.154 | 0.97 | |
| 21_T | 24_N | 1.148 | 0.97 | |
| 173_C | 207_V | 1.143 | 0.97 | |
| 20_V | 25_L | 1.143 | 0.97 | |
| 79_E | 232_D | 1.141 | 0.97 | |
| 69_F | 103_S | 1.135 | 0.97 | |
| 176_L | 207_V | 1.129 | 0.97 | |
| 23_S | 33_E | 1.124 | 0.97 | |
| 87_A | 230_I | 1.118 | 0.96 | |
| 49_L | 56_A | 1.116 | 0.96 | |
| 105_V | 108_L | 1.114 | 0.96 | |
| 9_A | 28_I | 1.106 | 0.96 | |
| 173_C | 205_L | 1.098 | 0.96 | |
| 221_A | 225_H | 1.095 | 0.96 | |
| 52_T | 55_G | 1.091 | 0.96 | |
| 13_M | 16_N | 1.068 | 0.95 | |
| 79_E | 209_H | 1.065 | 0.95 | |
| 125_A | 131_L | 1.058 | 0.95 | |
| 119_T | 137_K | 1.057 | 0.95 | |
| 194_K | 198_R | 1.056 | 0.95 | |
| 124_S | 131_L | 1.053 | 0.95 | |
| 104_T | 208_D | 1.044 | 0.94 | |
| 87_A | 108_L | 1.036 | 0.94 | |
| 204_A | 230_I | 1.032 | 0.94 | |
| 15_A | 58_L | 1.03 | 0.94 | |
| 12_Q | 16_N | 1.019 | 0.93 | |
| 198_R | 225_H | 1.013 | 0.93 | |
| 80_K | 211_K | 1.011 | 0.93 | |
| 241_A | 244_K | 1.007 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1stzA | 3 | 0.9405 | 100 | 0.498 | Contact Map | 0.267 |
| 3rrlB | 2 | 0.6627 | 100 | 0.518 | Contact Map | 0.572 |
| 2w48A | 4 | 0.9365 | 100 | 0.562 | Contact Map | 0.582 |
| 4io1A | 2 | 0.631 | 100 | 0.588 | Contact Map | 0.694 |
| 3l7oA | 2 | 0.5992 | 100 | 0.594 | Contact Map | 0.721 |
| 4gmkA | 2 | 0.6111 | 100 | 0.596 | Contact Map | 0.725 |
| 1o8bA | 2 | 0.6071 | 100 | 0.597 | Contact Map | 0.571 |
| 1m0sA | 2 | 0.6071 | 100 | 0.605 | Contact Map | 0.711 |
| 1uj6A | 1 | 0.6111 | 100 | 0.607 | Contact Map | 0.663 |
| 1lk5A | 4 | 0.6032 | 100 | 0.607 | Contact Map | 0.736 |
Sequence Conservation (Image Generated using WebLogo v3)