| UniProt: | P36930 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12162 | ||
| Length: | 259 (257) | ||
| Sequences: | 3458 | ||
| Seq/Len: | 13.46 |
| GATR
Paralog alert: 0.83 [within 20: 0.11] - ratio of genomes with paralogs Cluster includes: AGAR DEOR FUCR GATR GLPR SGCR SRLR ULAR YCIT YDJF YGBI YIHW |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 114_I | 212_V | 3.637 | 1.00 | |
| 101_M | 175_L | 3.29 | 1.00 | |
| 92_A | 95_K | 3.054 | 1.00 | |
| 106_D | 199_S | 2.811 | 1.00 | |
| 176_M | 206_A | 2.787 | 1.00 | |
| 144_T | 151_T | 2.529 | 1.00 | |
| 15_L | 30_V | 2.21 | 1.00 | |
| 175_L | 210_I | 2.199 | 1.00 | |
| 116_E | 136_A | 2.111 | 1.00 | |
| 203_V | 227_L | 2.067 | 1.00 | |
| 210_I | 234_I | 1.998 | 1.00 | |
| 104_I | 173_A | 1.996 | 1.00 | |
| 175_L | 208_K | 1.974 | 1.00 | |
| 93_A | 177_F | 1.942 | 1.00 | |
| 225_Q | 228_P | 1.925 | 1.00 | |
| 234_I | 257_I | 1.909 | 1.00 | |
| 15_L | 19_Q | 1.906 | 1.00 | |
| 127_I | 173_A | 1.901 | 1.00 | |
| 173_A | 202_M | 1.9 | 1.00 | |
| 93_A | 212_V | 1.894 | 1.00 | |
| 104_I | 202_M | 1.847 | 1.00 | |
| 215_S | 238_D | 1.841 | 1.00 | |
| 97_I | 118_L | 1.809 | 1.00 | |
| 27_L | 38_I | 1.804 | 1.00 | |
| 98_H | 101_M | 1.803 | 1.00 | |
| 208_K | 234_I | 1.799 | 1.00 | |
| 203_V | 209_V | 1.799 | 1.00 | |
| 105_L | 111_T | 1.789 | 1.00 | |
| 241_V | 246_K | 1.786 | 1.00 | |
| 126_V | 143_I | 1.76 | 1.00 | |
| 114_I | 177_F | 1.756 | 1.00 | |
| 11_K | 14_Q | 1.752 | 1.00 | |
| 91_Q | 117_G | 1.75 | 1.00 | |
| 87_N | 113_L | 1.75 | 1.00 | |
| 101_M | 174_D | 1.749 | 1.00 | |
| 246_K | 250_Q | 1.73 | 1.00 | |
| 228_P | 231_K | 1.723 | 1.00 | |
| 94_V | 117_G | 1.698 | 1.00 | |
| 99_E | 121_A | 1.691 | 1.00 | |
| 99_E | 122_K | 1.679 | 1.00 | |
| 166_R | 169_Q | 1.674 | 1.00 | |
| 148_C | 164_A | 1.67 | 1.00 | |
| 90_A | 117_G | 1.668 | 1.00 | |
| 82_A | 216_S | 1.663 | 1.00 | |
| 33_A | 38_I | 1.656 | 1.00 | |
| 107_S | 158_S | 1.64 | 1.00 | |
| 174_D | 207_N | 1.621 | 1.00 | |
| 113_L | 116_E | 1.611 | 1.00 | |
| 169_Q | 201_A | 1.603 | 1.00 | |
| 147_V | 159_M | 1.577 | 1.00 | |
| 82_A | 85_P | 1.57 | 1.00 | |
| 9_R | 48_K | 1.558 | 1.00 | |
| 134_A | 147_V | 1.544 | 1.00 | |
| 42_L | 58_A | 1.539 | 1.00 | |
| 13_I | 50_V | 1.532 | 1.00 | |
| 21_T | 59_A | 1.494 | 1.00 | |
| 92_A | 257_I | 1.49 | 1.00 | |
| 189_I | 211_A | 1.484 | 1.00 | |
| 11_K | 15_L | 1.479 | 1.00 | |
| 148_C | 167_S | 1.472 | 1.00 | |
| 13_I | 16_V | 1.464 | 1.00 | |
| 152_V | 159_M | 1.463 | 1.00 | |
| 166_R | 170_D | 1.455 | 1.00 | |
| 19_Q | 26_D | 1.429 | 1.00 | |
| 126_V | 137_L | 1.423 | 1.00 | |
| 211_A | 232_I | 1.419 | 1.00 | |
| 36_A | 40_A | 1.403 | 0.99 | |
| 209_V | 232_I | 1.401 | 0.99 | |
| 177_F | 210_I | 1.393 | 0.99 | |
| 10_N | 14_Q | 1.392 | 0.99 | |
| 100_G | 123_N | 1.386 | 0.99 | |
| 148_C | 159_M | 1.385 | 0.99 | |
| 165_E | 197_S | 1.381 | 0.99 | |
| 96_M | 236_I | 1.371 | 0.99 | |
| 218_F | 235_I | 1.369 | 0.99 | |
| 201_A | 205_A | 1.363 | 0.99 | |
| 94_V | 114_I | 1.355 | 0.99 | |
| 96_M | 210_I | 1.353 | 0.99 | |
| 15_L | 22_V | 1.351 | 0.99 | |
| 169_Q | 204_T | 1.333 | 0.99 | |
| 201_A | 204_T | 1.329 | 0.99 | |
| 90_A | 94_V | 1.325 | 0.99 | |
| 247_L | 251_K | 1.323 | 0.99 | |
| 12_I | 27_L | 1.276 | 0.99 | |
| 125_T | 146_V | 1.275 | 0.99 | |
| 242_S | 245_D | 1.27 | 0.99 | |
| 16_V | 60_K | 1.263 | 0.99 | |
| 208_K | 233_D | 1.259 | 0.99 | |
| 189_I | 232_I | 1.256 | 0.99 | |
| 87_N | 117_G | 1.239 | 0.98 | |
| 164_A | 198_I | 1.236 | 0.98 | |
| 182_G | 190_T | 1.223 | 0.98 | |
| 11_K | 31_F | 1.222 | 0.98 | |
| 86_K | 109_S | 1.22 | 0.98 | |
| 180_A | 211_A | 1.219 | 0.98 | |
| 94_V | 97_I | 1.216 | 0.98 | |
| 183_I | 218_F | 1.207 | 0.98 | |
| 16_V | 51_V | 1.206 | 0.98 | |
| 75_F | 109_S | 1.205 | 0.98 | |
| 51_V | 58_A | 1.182 | 0.98 | |
| 108_G | 111_T | 1.176 | 0.98 | |
| 22_V | 27_L | 1.174 | 0.98 | |
| 85_P | 238_D | 1.173 | 0.98 | |
| 83_S | 113_L | 1.172 | 0.98 | |
| 180_A | 226_V | 1.167 | 0.97 | |
| 218_F | 241_V | 1.167 | 0.97 | |
| 24_V | 42_L | 1.165 | 0.97 | |
| 23_L | 26_D | 1.16 | 0.97 | |
| 180_A | 213_L | 1.159 | 0.97 | |
| 54_F | 57_G | 1.151 | 0.97 | |
| 151_T | 195_G | 1.138 | 0.97 | |
| 96_M | 257_I | 1.138 | 0.97 | |
| 183_I | 213_L | 1.136 | 0.97 | |
| 115_A | 137_L | 1.136 | 0.97 | |
| 93_A | 236_I | 1.135 | 0.97 | |
| 25_Q | 35_E | 1.117 | 0.96 | |
| 111_T | 114_I | 1.114 | 0.96 | |
| 227_L | 231_K | 1.108 | 0.96 | |
| 99_E | 123_N | 1.101 | 0.96 | |
| 110_T | 214_D | 1.096 | 0.96 | |
| 125_T | 144_T | 1.094 | 0.96 | |
| 85_P | 215_S | 1.093 | 0.96 | |
| 15_L | 18_E | 1.092 | 0.96 | |
| 11_K | 30_V | 1.09 | 0.96 | |
| 115_A | 136_A | 1.085 | 0.96 | |
| 93_A | 114_I | 1.083 | 0.96 | |
| 247_L | 250_Q | 1.052 | 0.95 | |
| 210_I | 236_I | 1.042 | 0.94 | |
| 17_N | 60_K | 1.039 | 0.94 | |
| 200_G | 204_T | 1.038 | 0.94 | |
| 86_K | 217_K | 1.037 | 0.94 | |
| 9_R | 44_F | 1.022 | 0.93 | |
| 204_T | 231_K | 1.015 | 0.93 | |
| 7_E | 10_N | 1.008 | 0.93 | |
| 14_Q | 18_E | 1.008 | 0.93 | |
| 89_I | 110_T | 1.003 | 0.93 | |
| 181_D | 191_T | 1.002 | 0.92 | |
| 112_M | 132_P | 1.002 | 0.92 | |
| 97_I | 177_F | 1.001 | 0.92 | |
| 168_L | 201_A | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1stzA | 3 | 0.9382 | 100 | 0.494 | Contact Map | 0.274 |
| 3rrlB | 2 | 0.6486 | 100 | 0.518 | Contact Map | 0.586 |
| 2w48A | 4 | 0.9112 | 100 | 0.564 | Contact Map | 0.599 |
| 4io1A | 2 | 0.6139 | 100 | 0.6 | Contact Map | 0.697 |
| 3l7oA | 2 | 0.5869 | 100 | 0.606 | Contact Map | 0.73 |
| 4gmkA | 2 | 0.5985 | 100 | 0.606 | Contact Map | 0.744 |
| 1o8bA | 2 | 0.5946 | 100 | 0.612 | Contact Map | 0.598 |
| 2o0mA | 1 | 0.9537 | 100 | 0.614 | Contact Map | 0.525 |
| 1m0sA | 2 | 0.5907 | 100 | 0.617 | Contact Map | 0.717 |
| 1lk5A | 4 | 0.5869 | 100 | 0.62 | Contact Map | 0.755 |
Sequence Conservation (Image Generated using WebLogo v3)