| UniProt: | P0A9W0 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12491 | ||
| Length: | 251 (250) | ||
| Sequences: | 3549 | ||
| Seq/Len: | 14.20 |
| ULAR
Paralog alert: 0.83 [within 20: 0.11] - ratio of genomes with paralogs Cluster includes: AGAR DEOR FUCR GATR GLPR SGCR SRLR ULAR YCIT YDJF YGBI YIHW |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 108_L | 204_L | 3.702 | 1.00 | |
| 95_E | 167_W | 3.264 | 1.00 | |
| 86_A | 89_Q | 3.137 | 1.00 | |
| 100_N | 191_E | 2.857 | 1.00 | |
| 168_M | 198_V | 2.748 | 1.00 | |
| 137_S | 144_Q | 2.685 | 1.00 | |
| 13_M | 28_R | 2.323 | 1.00 | |
| 167_W | 202_V | 2.249 | 1.00 | |
| 110_R | 129_Y | 2.221 | 1.00 | |
| 154_S | 157_G | 2.158 | 1.00 | |
| 195_L | 219_S | 2.116 | 1.00 | |
| 202_V | 226_M | 2.095 | 1.00 | |
| 87_A | 204_L | 2.026 | 1.00 | |
| 217_L | 220_R | 1.997 | 1.00 | |
| 233_A | 238_L | 1.984 | 1.00 | |
| 13_M | 17_L | 1.917 | 1.00 | |
| 167_W | 200_K | 1.869 | 1.00 | |
| 87_A | 169_F | 1.869 | 1.00 | |
| 98_V | 194_M | 1.86 | 1.00 | |
| 92_N | 95_E | 1.858 | 1.00 | |
| 99_I | 105_A | 1.85 | 1.00 | |
| 226_M | 249_L | 1.847 | 1.00 | |
| 85_K | 111_E | 1.842 | 1.00 | |
| 25_V | 36_A | 1.836 | 1.00 | |
| 195_L | 201_L | 1.827 | 1.00 | |
| 93_P | 115_K | 1.827 | 1.00 | |
| 200_K | 226_M | 1.787 | 1.00 | |
| 91_V | 112_M | 1.779 | 1.00 | |
| 108_L | 169_F | 1.776 | 1.00 | |
| 81_V | 107_L | 1.775 | 1.00 | |
| 119_I | 136_D | 1.775 | 1.00 | |
| 238_L | 242_E | 1.774 | 1.00 | |
| 9_I | 12_E | 1.77 | 1.00 | |
| 220_R | 223_Q | 1.763 | 1.00 | |
| 165_G | 194_M | 1.754 | 1.00 | |
| 88_S | 111_E | 1.731 | 1.00 | |
| 98_V | 165_G | 1.713 | 1.00 | |
| 107_L | 110_R | 1.696 | 1.00 | |
| 207_S | 230_G | 1.691 | 1.00 | |
| 31_I | 36_A | 1.675 | 1.00 | |
| 76_N | 208_S | 1.655 | 1.00 | |
| 84_A | 111_E | 1.644 | 1.00 | |
| 127_A | 140_I | 1.592 | 1.00 | |
| 76_N | 79_E | 1.567 | 1.00 | |
| 11_L | 48_K | 1.564 | 1.00 | |
| 95_E | 166_H | 1.563 | 1.00 | |
| 7_H | 46_S | 1.553 | 1.00 | |
| 9_I | 13_M | 1.541 | 1.00 | |
| 40_I | 56_A | 1.538 | 1.00 | |
| 11_L | 14_L | 1.515 | 1.00 | |
| 19_F | 57_E | 1.482 | 1.00 | |
| 119_I | 130_L | 1.477 | 1.00 | |
| 120_I | 165_G | 1.456 | 1.00 | |
| 8_Q | 12_E | 1.446 | 1.00 | |
| 90_L | 228_I | 1.443 | 1.00 | |
| 201_L | 224_I | 1.434 | 1.00 | |
| 34_A | 38_R | 1.429 | 1.00 | |
| 17_L | 24_K | 1.427 | 1.00 | |
| 166_H | 199_G | 1.423 | 1.00 | |
| 180_L | 203_V | 1.418 | 1.00 | |
| 90_L | 202_V | 1.41 | 1.00 | |
| 193_K | 197_V | 1.405 | 0.99 | |
| 94_G | 116_P | 1.404 | 0.99 | |
| 169_F | 202_V | 1.396 | 0.99 | |
| 93_P | 116_P | 1.39 | 0.99 | |
| 203_V | 224_I | 1.384 | 0.99 | |
| 13_M | 20_V | 1.363 | 0.99 | |
| 145_Y | 152_T | 1.359 | 0.99 | |
| 86_A | 249_L | 1.357 | 0.99 | |
| 118_Q | 139_I | 1.355 | 0.99 | |
| 193_K | 196_S | 1.352 | 0.99 | |
| 140_I | 152_T | 1.346 | 0.99 | |
| 141_M | 157_G | 1.341 | 0.99 | |
| 88_S | 108_L | 1.339 | 0.99 | |
| 10_L | 25_V | 1.315 | 0.99 | |
| 84_A | 88_S | 1.309 | 0.99 | |
| 200_K | 225_D | 1.308 | 0.99 | |
| 239_Q | 243_A | 1.307 | 0.99 | |
| 234_N | 237_I | 1.294 | 0.99 | |
| 151_I | 157_G | 1.285 | 0.99 | |
| 81_V | 111_E | 1.285 | 0.99 | |
| 88_S | 91_V | 1.284 | 0.99 | |
| 210_I | 227_L | 1.281 | 0.99 | |
| 101_C | 151_I | 1.275 | 0.99 | |
| 151_I | 154_S | 1.255 | 0.99 | |
| 9_I | 29_L | 1.254 | 0.99 | |
| 14_L | 49_L | 1.245 | 0.98 | |
| 180_L | 224_I | 1.241 | 0.98 | |
| 175_L | 210_I | 1.238 | 0.98 | |
| 210_I | 233_A | 1.234 | 0.98 | |
| 69_M | 103_S | 1.224 | 0.98 | |
| 144_Q | 186_L | 1.222 | 0.98 | |
| 102_G | 105_A | 1.221 | 0.98 | |
| 80_K | 103_S | 1.213 | 0.98 | |
| 174_G | 181_Y | 1.207 | 0.98 | |
| 77_H | 107_L | 1.205 | 0.98 | |
| 49_L | 56_A | 1.205 | 0.98 | |
| 20_V | 25_V | 1.202 | 0.98 | |
| 172_G | 218_F | 1.196 | 0.98 | |
| 21_T | 24_K | 1.195 | 0.98 | |
| 23_E | 33_P | 1.187 | 0.98 | |
| 14_L | 58_A | 1.185 | 0.98 | |
| 172_G | 205_V | 1.185 | 0.98 | |
| 22_V | 40_I | 1.174 | 0.98 | |
| 52_V | 55_G | 1.157 | 0.97 | |
| 159_E | 162_L | 1.154 | 0.97 | |
| 219_S | 223_Q | 1.146 | 0.97 | |
| 175_L | 205_V | 1.146 | 0.97 | |
| 202_V | 228_I | 1.141 | 0.97 | |
| 13_M | 16_Q | 1.141 | 0.97 | |
| 158_S | 189_M | 1.141 | 0.97 | |
| 105_A | 108_L | 1.138 | 0.97 | |
| 9_I | 28_R | 1.136 | 0.97 | |
| 79_E | 230_G | 1.119 | 0.96 | |
| 118_Q | 137_S | 1.116 | 0.96 | |
| 87_A | 108_L | 1.1 | 0.96 | |
| 79_E | 207_S | 1.1 | 0.96 | |
| 172_G | 203_V | 1.091 | 0.96 | |
| 192_Q | 196_S | 1.085 | 0.96 | |
| 109_G | 130_L | 1.084 | 0.96 | |
| 104_T | 206_D | 1.08 | 0.95 | |
| 87_A | 228_I | 1.064 | 0.95 | |
| 90_L | 249_L | 1.059 | 0.95 | |
| 109_G | 129_Y | 1.058 | 0.95 | |
| 7_H | 42_K | 1.053 | 0.95 | |
| 239_Q | 242_E | 1.048 | 0.94 | |
| 173_K | 182_K | 1.046 | 0.94 | |
| 139_I | 144_Q | 1.044 | 0.94 | |
| 146_N | 187_T | 1.044 | 0.94 | |
| 80_K | 209_K | 1.035 | 0.94 | |
| 106_F | 125_P | 1.034 | 0.94 | |
| 98_V | 197_V | 1.031 | 0.94 | |
| 154_S | 158_S | 1.031 | 0.94 | |
| 196_S | 223_Q | 1.03 | 0.94 | |
| 83_I | 104_T | 1.01 | 0.93 | |
| 121_T | 127_A | 1.009 | 0.93 | |
| 77_H | 81_V | 1.006 | 0.93 | |
| 12_E | 16_Q | 1.005 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1stzA | 3 | 0.9243 | 100 | 0.514 | Contact Map | 0.259 |
| 3rrlB | 2 | 0.6653 | 100 | 0.527 | Contact Map | 0.597 |
| 2w48A | 4 | 0.9323 | 100 | 0.567 | Contact Map | 0.604 |
| 3l7oA | 2 | 0.5976 | 100 | 0.603 | Contact Map | 0.72 |
| 4io1A | 2 | 0.6295 | 100 | 0.603 | Contact Map | 0.686 |
| 4gmkA | 2 | 0.6096 | 100 | 0.604 | Contact Map | 0.73 |
| 1o8bA | 2 | 0.6056 | 100 | 0.609 | Contact Map | 0.587 |
| 2o0mA | 1 | 0.9562 | 100 | 0.609 | Contact Map | 0.529 |
| 1m0sA | 2 | 0.6056 | 100 | 0.616 | Contact Map | 0.722 |
| 1uj6A | 1 | 0.6096 | 100 | 0.618 | Contact Map | 0.642 |
Sequence Conservation (Image Generated using WebLogo v3)