| UniProt: | P0ACK5 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10223 | ||
| Length: | 252 (249) | ||
| Sequences: | 3458 | ||
| Seq/Len: | 13.89 |
| DEOR
Paralog alert: 0.83 [within 20: 0.11] - ratio of genomes with paralogs Cluster includes: AGAR DEOR FUCR GATR GLPR SGCR SRLR ULAR YCIT YDJF YGBI YIHW |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 107_I | 206_V | 3.608 | 1.00 | |
| 94_Q | 168_I | 3.309 | 1.00 | |
| 85_L | 88_T | 3.115 | 1.00 | |
| 169_A | 200_A | 2.817 | 1.00 | |
| 99_D | 193_K | 2.755 | 1.00 | |
| 137_R | 144_E | 2.564 | 1.00 | |
| 15_E | 30_L | 2.213 | 1.00 | |
| 168_I | 204_V | 2.178 | 1.00 | |
| 109_E | 129_A | 2.095 | 1.00 | |
| 197_M | 221_G | 2.068 | 1.00 | |
| 204_V | 228_I | 1.994 | 1.00 | |
| 97_F | 166_P | 1.968 | 1.00 | |
| 219_R | 222_D | 1.927 | 1.00 | |
| 228_I | 251_M | 1.909 | 1.00 | |
| 15_E | 19_S | 1.901 | 1.00 | |
| 166_P | 196_A | 1.898 | 1.00 | |
| 168_I | 202_K | 1.897 | 1.00 | |
| 86_A | 206_V | 1.894 | 1.00 | |
| 86_A | 170_F | 1.863 | 1.00 | |
| 120_V | 166_P | 1.861 | 1.00 | |
| 90_V | 111_I | 1.841 | 1.00 | |
| 97_F | 196_A | 1.827 | 1.00 | |
| 209_H | 232_D | 1.817 | 1.00 | |
| 235_P | 240_V | 1.804 | 1.00 | |
| 197_M | 203_H | 1.798 | 1.00 | |
| 11_Q | 14_Q | 1.796 | 1.00 | |
| 91_E | 94_Q | 1.787 | 1.00 | |
| 27_A | 38_I | 1.779 | 1.00 | |
| 202_K | 228_I | 1.777 | 1.00 | |
| 119_A | 136_C | 1.757 | 1.00 | |
| 84_K | 110_A | 1.756 | 1.00 | |
| 98_F | 104_T | 1.754 | 1.00 | |
| 107_I | 170_F | 1.752 | 1.00 | |
| 92_P | 115_I | 1.749 | 1.00 | |
| 80_R | 106_W | 1.727 | 1.00 | |
| 94_Q | 167_D | 1.718 | 1.00 | |
| 87_A | 110_A | 1.696 | 1.00 | |
| 222_D | 225_R | 1.696 | 1.00 | |
| 240_V | 244_Q | 1.684 | 1.00 | |
| 141_C | 157_F | 1.679 | 1.00 | |
| 33_V | 38_I | 1.667 | 1.00 | |
| 83_A | 110_A | 1.661 | 1.00 | |
| 159_Q | 162_N | 1.642 | 1.00 | |
| 75_L | 210_S | 1.614 | 1.00 | |
| 100_C | 151_I | 1.588 | 1.00 | |
| 162_N | 195_W | 1.587 | 1.00 | |
| 167_D | 201_Q | 1.571 | 1.00 | |
| 182_A | 205_L | 1.569 | 1.00 | |
| 106_W | 109_E | 1.562 | 1.00 | |
| 140_L | 152_F | 1.557 | 1.00 | |
| 127_F | 140_L | 1.555 | 1.00 | |
| 9_I | 48_P | 1.552 | 1.00 | |
| 75_L | 78_E | 1.551 | 1.00 | |
| 92_P | 114_E | 1.541 | 1.00 | |
| 42_L | 55_Y | 1.527 | 1.00 | |
| 21_K | 56_I | 1.474 | 1.00 | |
| 13_L | 16_L | 1.471 | 1.00 | |
| 145_F | 152_F | 1.47 | 1.00 | |
| 141_C | 160_T | 1.462 | 1.00 | |
| 170_F | 204_V | 1.46 | 1.00 | |
| 11_Q | 15_E | 1.455 | 1.00 | |
| 159_Q | 163_N | 1.449 | 1.00 | |
| 119_A | 130_L | 1.438 | 1.00 | |
| 93_D | 116_P | 1.429 | 1.00 | |
| 89_L | 230_V | 1.409 | 1.00 | |
| 203_H | 226_F | 1.401 | 0.99 | |
| 36_M | 40_R | 1.398 | 0.99 | |
| 195_W | 199_M | 1.396 | 0.99 | |
| 158_Q | 191_P | 1.388 | 0.99 | |
| 19_S | 26_D | 1.377 | 0.99 | |
| 15_E | 22_L | 1.364 | 0.99 | |
| 141_C | 152_F | 1.364 | 0.99 | |
| 162_N | 198_S | 1.363 | 0.99 | |
| 212_F | 229_V | 1.356 | 0.99 | |
| 89_L | 204_V | 1.354 | 0.99 | |
| 85_L | 251_M | 1.351 | 0.99 | |
| 10_G | 14_Q | 1.335 | 0.99 | |
| 195_W | 198_S | 1.329 | 0.99 | |
| 87_A | 107_I | 1.319 | 0.99 | |
| 241_K | 245_T | 1.313 | 0.99 | |
| 205_L | 226_F | 1.31 | 0.99 | |
| 236_E | 239_Y | 1.281 | 0.99 | |
| 83_A | 87_A | 1.279 | 0.99 | |
| 80_R | 110_A | 1.278 | 0.99 | |
| 182_A | 226_F | 1.276 | 0.99 | |
| 11_Q | 31_L | 1.254 | 0.99 | |
| 12_L | 27_A | 1.25 | 0.99 | |
| 202_K | 227_D | 1.242 | 0.98 | |
| 118_T | 139_F | 1.242 | 0.98 | |
| 144_E | 188_E | 1.233 | 0.98 | |
| 68_L | 102_T | 1.224 | 0.98 | |
| 212_F | 235_P | 1.222 | 0.98 | |
| 173_A | 220_M | 1.222 | 0.98 | |
| 157_F | 192_V | 1.216 | 0.98 | |
| 87_A | 90_V | 1.213 | 0.98 | |
| 175_G | 183_T | 1.206 | 0.98 | |
| 176_V | 212_F | 1.199 | 0.98 | |
| 24_L | 42_L | 1.196 | 0.98 | |
| 79_K | 102_T | 1.176 | 0.98 | |
| 23_H | 26_D | 1.168 | 0.97 | |
| 173_A | 207_V | 1.164 | 0.97 | |
| 108_I | 130_L | 1.161 | 0.97 | |
| 76_V | 106_W | 1.148 | 0.97 | |
| 22_L | 27_A | 1.147 | 0.97 | |
| 11_Q | 30_L | 1.138 | 0.97 | |
| 25_K | 35_E | 1.131 | 0.97 | |
| 78_E | 232_D | 1.13 | 0.97 | |
| 101_G | 104_T | 1.129 | 0.97 | |
| 51_L | 54_G | 1.126 | 0.97 | |
| 221_G | 225_R | 1.122 | 0.97 | |
| 176_V | 207_V | 1.117 | 0.96 | |
| 16_L | 57_V | 1.108 | 0.96 | |
| 173_A | 205_L | 1.107 | 0.96 | |
| 118_T | 137_R | 1.107 | 0.96 | |
| 104_T | 107_I | 1.106 | 0.96 | |
| 92_P | 116_P | 1.091 | 0.96 | |
| 86_A | 230_V | 1.087 | 0.96 | |
| 15_E | 18_R | 1.081 | 0.95 | |
| 9_I | 44_N | 1.067 | 0.95 | |
| 112_D | 133_K | 1.057 | 0.95 | |
| 204_V | 230_V | 1.05 | 0.94 | |
| 17_K | 57_V | 1.044 | 0.94 | |
| 78_E | 209_H | 1.043 | 0.94 | |
| 86_A | 107_I | 1.037 | 0.94 | |
| 103_T | 208_D | 1.035 | 0.94 | |
| 146_H | 189_E | 1.035 | 0.94 | |
| 194_H | 198_S | 1.034 | 0.94 | |
| 161_L | 195_W | 1.023 | 0.93 | |
| 89_L | 251_M | 1.021 | 0.93 | |
| 198_S | 225_R | 1.006 | 0.93 | |
| 79_K | 211_K | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3rrlB | 2 | 0.6667 | 100 | 0.512 | Contact Map | 0.582 |
| 1stzA | 3 | 0.9405 | 100 | 0.519 | Contact Map | 0.264 |
| 4io1A | 2 | 0.631 | 100 | 0.591 | Contact Map | 0.694 |
| 2w48A | 4 | 0.9286 | 100 | 0.595 | Contact Map | 0.615 |
| 3l7oA | 2 | 0.5992 | 100 | 0.597 | Contact Map | 0.727 |
| 4gmkA | 2 | 0.6111 | 100 | 0.598 | Contact Map | 0.731 |
| 1o8bA | 2 | 0.6071 | 100 | 0.602 | Contact Map | 0.57 |
| 1m0sA | 2 | 0.6071 | 100 | 0.608 | Contact Map | 0.711 |
| 1uj6A | 1 | 0.6111 | 100 | 0.61 | Contact Map | 0.654 |
| 1lk5A | 4 | 0.6032 | 100 | 0.611 | Contact Map | 0.736 |
Sequence Conservation (Image Generated using WebLogo v3)