| UniProt: | P0ACK8 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10353 | ||
| Length: | 243 (237) | ||
| Sequences: | 3351 | ||
| Seq/Len: | 14.14 |
| FUCR
Paralog alert: 0.83 [within 20: 0.11] - ratio of genomes with paralogs Cluster includes: AGAR DEOR FUCR GATR GLPR SGCR SRLR ULAR YCIT YDJF YGBI YIHW |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 108_L | 206_L | 3.562 | 1.00 | |
| 95_M | 168_L | 3.279 | 1.00 | |
| 86_E | 89_A | 3.052 | 1.00 | |
| 100_D | 193_K | 2.832 | 1.00 | |
| 169_F | 200_A | 2.829 | 1.00 | |
| 137_Q | 144_T | 2.569 | 1.00 | |
| 168_L | 204_L | 2.239 | 1.00 | |
| 12_L | 27_Q | 2.221 | 1.00 | |
| 110_R | 129_E | 2.14 | 1.00 | |
| 204_L | 228_H | 2.12 | 1.00 | |
| 197_L | 221_G | 2.084 | 1.00 | |
| 98_A | 166_I | 1.994 | 1.00 | |
| 168_L | 202_Q | 1.941 | 1.00 | |
| 87_A | 170_I | 1.932 | 1.00 | |
| 166_I | 196_L | 1.926 | 1.00 | |
| 219_R | 222_H | 1.917 | 1.00 | |
| 120_F | 166_I | 1.911 | 1.00 | |
| 87_A | 206_L | 1.869 | 1.00 | |
| 12_L | 16_H | 1.855 | 1.00 | |
| 98_A | 196_L | 1.828 | 1.00 | |
| 93_E | 115_I | 1.827 | 1.00 | |
| 209_K | 232_D | 1.822 | 1.00 | |
| 24_L | 35_I | 1.809 | 1.00 | |
| 197_L | 203_S | 1.803 | 1.00 | |
| 92_E | 95_M | 1.786 | 1.00 | |
| 91_I | 112_L | 1.78 | 1.00 | |
| 99_L | 105_C | 1.776 | 1.00 | |
| 85_R | 111_Q | 1.774 | 1.00 | |
| 202_Q | 228_H | 1.736 | 1.00 | |
| 108_L | 170_I | 1.736 | 1.00 | |
| 81_A | 107_Y | 1.73 | 1.00 | |
| 8_A | 11_D | 1.724 | 1.00 | |
| 119_V | 136_I | 1.705 | 1.00 | |
| 159_S | 162_K | 1.702 | 1.00 | |
| 141_S | 157_L | 1.665 | 1.00 | |
| 222_H | 225_E | 1.66 | 1.00 | |
| 30_V | 35_I | 1.646 | 1.00 | |
| 95_M | 167_D | 1.64 | 1.00 | |
| 84_A | 111_Q | 1.637 | 1.00 | |
| 88_L | 111_Q | 1.609 | 1.00 | |
| 107_Y | 110_R | 1.592 | 1.00 | |
| 76_H | 210_S | 1.588 | 1.00 | |
| 162_K | 195_M | 1.586 | 1.00 | |
| 140_S | 152_Y | 1.572 | 1.00 | |
| 6_Q | 45_Q | 1.563 | 1.00 | |
| 167_D | 201_A | 1.563 | 1.00 | |
| 10_V | 47_K | 1.545 | 1.00 | |
| 101_A | 151_C | 1.541 | 1.00 | |
| 127_C | 140_S | 1.525 | 1.00 | |
| 182_L | 205_L | 1.525 | 1.00 | |
| 8_A | 12_L | 1.503 | 1.00 | |
| 145_L | 152_Y | 1.495 | 1.00 | |
| 76_H | 79_H | 1.488 | 1.00 | |
| 39_L | 55_A | 1.487 | 1.00 | |
| 18_S | 56_K | 1.486 | 1.00 | |
| 141_S | 160_Q | 1.482 | 1.00 | |
| 212_F | 229_I | 1.466 | 1.00 | |
| 94_G | 116_N | 1.463 | 1.00 | |
| 170_I | 204_L | 1.441 | 1.00 | |
| 7_Q | 11_D | 1.428 | 1.00 | |
| 16_H | 23_A | 1.422 | 1.00 | |
| 159_S | 163_S | 1.421 | 1.00 | |
| 10_V | 13_L | 1.418 | 1.00 | |
| 119_V | 130_L | 1.404 | 0.99 | |
| 162_K | 198_K | 1.4 | 0.99 | |
| 33_E | 37_R | 1.397 | 0.99 | |
| 195_M | 198_K | 1.387 | 0.99 | |
| 158_I | 191_D | 1.387 | 0.99 | |
| 195_M | 199_R | 1.383 | 0.99 | |
| 203_S | 226_V | 1.375 | 0.99 | |
| 90_W | 204_L | 1.369 | 0.99 | |
| 90_W | 230_I | 1.362 | 0.99 | |
| 205_L | 226_V | 1.346 | 0.99 | |
| 141_S | 152_Y | 1.328 | 0.99 | |
| 202_Q | 227_T | 1.325 | 0.99 | |
| 88_L | 108_L | 1.307 | 0.99 | |
| 12_L | 19_L | 1.297 | 0.99 | |
| 81_A | 111_Q | 1.294 | 0.99 | |
| 93_E | 116_N | 1.276 | 0.99 | |
| 118_Q | 139_I | 1.247 | 0.99 | |
| 9_I | 24_L | 1.245 | 0.98 | |
| 182_L | 226_V | 1.239 | 0.98 | |
| 8_A | 28_L | 1.238 | 0.98 | |
| 13_L | 57_Y | 1.23 | 0.98 | |
| 84_A | 88_L | 1.224 | 0.98 | |
| 157_L | 192_Y | 1.219 | 0.98 | |
| 69_F | 103_S | 1.215 | 0.98 | |
| 20_T | 23_A | 1.21 | 0.98 | |
| 175_G | 183_W | 1.202 | 0.98 | |
| 144_T | 188_I | 1.198 | 0.98 | |
| 176_I | 212_F | 1.186 | 0.98 | |
| 13_L | 48_I | 1.179 | 0.98 | |
| 80_K | 103_S | 1.175 | 0.98 | |
| 173_C | 220_I | 1.165 | 0.97 | |
| 77_Y | 107_Y | 1.161 | 0.97 | |
| 79_H | 232_D | 1.156 | 0.97 | |
| 19_L | 24_L | 1.148 | 0.97 | |
| 105_C | 108_L | 1.144 | 0.97 | |
| 109_A | 130_L | 1.142 | 0.97 | |
| 173_C | 207_I | 1.14 | 0.97 | |
| 8_A | 27_Q | 1.133 | 0.97 | |
| 88_L | 91_I | 1.133 | 0.97 | |
| 102_S | 105_C | 1.132 | 0.97 | |
| 22_E | 32_K | 1.131 | 0.97 | |
| 51_N | 54_R | 1.128 | 0.97 | |
| 21_T | 39_L | 1.126 | 0.97 | |
| 176_I | 207_I | 1.123 | 0.97 | |
| 12_L | 15_N | 1.104 | 0.96 | |
| 87_A | 230_I | 1.104 | 0.96 | |
| 221_G | 225_E | 1.101 | 0.96 | |
| 173_C | 205_L | 1.1 | 0.96 | |
| 79_H | 209_K | 1.099 | 0.96 | |
| 48_I | 55_A | 1.087 | 0.96 | |
| 113_P | 133_R | 1.077 | 0.95 | |
| 118_Q | 137_Q | 1.076 | 0.95 | |
| 204_L | 230_I | 1.065 | 0.95 | |
| 212_F | 235_Q | 1.058 | 0.95 | |
| 109_A | 129_E | 1.053 | 0.95 | |
| 104_T | 208_D | 1.052 | 0.95 | |
| 194_S | 198_K | 1.044 | 0.94 | |
| 87_A | 108_L | 1.034 | 0.94 | |
| 98_A | 199_R | 1.029 | 0.94 | |
| 141_S | 161_L | 1.016 | 0.93 | |
| 204_L | 227_T | 1.013 | 0.93 | |
| 6_Q | 41_E | 1.006 | 0.93 | |
| 198_K | 225_E | 1.002 | 0.92 | |
| 80_K | 211_K | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3rrlB | 2 | 0.6749 | 100 | 0.509 | Contact Map | 0.58 |
| 1stzA | 3 | 0.9342 | 100 | 0.514 | Contact Map | 0.273 |
| 2w48A | 4 | 0.9671 | 100 | 0.579 | Contact Map | 0.61 |
| 4io1A | 2 | 0.6379 | 100 | 0.599 | Contact Map | 0.69 |
| 4gmkA | 2 | 0.6173 | 100 | 0.612 | Contact Map | 0.74 |
| 3l7oA | 2 | 0.6008 | 100 | 0.613 | Contact Map | 0.731 |
| 1o8bA | 2 | 0.6132 | 100 | 0.616 | Contact Map | 0.584 |
| 1m0sA | 2 | 0.6132 | 99.9 | 0.617 | Contact Map | 0.714 |
| 2pjmA | 4 | 0.6049 | 99.9 | 0.623 | Contact Map | 0.653 |
| 1uj6A | 1 | 0.6049 | 99.9 | 0.623 | Contact Map | 0.655 |
Sequence Conservation (Image Generated using WebLogo v3)