| UniProt: | P0ACL0 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10400 | ||
| Length: | 252 (252) | ||
| Sequences: | 3471 | ||
| Seq/Len: | 13.77 |
| GLPR
Paralog alert: 0.83 [within 20: 0.11] - ratio of genomes with paralogs Cluster includes: AGAR DEOR FUCR GATR GLPR SGCR SRLR ULAR YCIT YDJF YGBI YIHW |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 106_V | 205_V | 3.595 | 1.00 | |
| 93_S | 167_F | 3.242 | 1.00 | |
| 84_K | 87_E | 3.063 | 1.00 | |
| 98_D | 192_K | 2.757 | 1.00 | |
| 168_G | 199_S | 2.754 | 1.00 | |
| 136_R | 143_E | 2.585 | 1.00 | |
| 13_L | 28_H | 2.213 | 1.00 | |
| 167_F | 203_M | 2.156 | 1.00 | |
| 108_H | 128_T | 2.128 | 1.00 | |
| 196_I | 220_G | 2.065 | 1.00 | |
| 96_F | 165_L | 1.987 | 1.00 | |
| 203_M | 227_A | 1.971 | 1.00 | |
| 218_N | 221_S | 1.939 | 1.00 | |
| 227_A | 250_E | 1.918 | 1.00 | |
| 167_F | 201_H | 1.909 | 1.00 | |
| 85_V | 169_I | 1.879 | 1.00 | |
| 119_V | 165_L | 1.863 | 1.00 | |
| 85_V | 205_V | 1.857 | 1.00 | |
| 165_L | 195_I | 1.854 | 1.00 | |
| 13_L | 17_Q | 1.842 | 1.00 | |
| 196_I | 202_V | 1.827 | 1.00 | |
| 89_I | 110_L | 1.816 | 1.00 | |
| 96_F | 195_I | 1.816 | 1.00 | |
| 208_H | 231_D | 1.815 | 1.00 | |
| 25_L | 36_I | 1.797 | 1.00 | |
| 90_P | 93_S | 1.757 | 1.00 | |
| 201_H | 227_A | 1.754 | 1.00 | |
| 97_I | 103_P | 1.75 | 1.00 | |
| 106_V | 169_I | 1.75 | 1.00 | |
| 234_P | 239_M | 1.743 | 1.00 | |
| 91_N | 114_S | 1.74 | 1.00 | |
| 83_R | 109_A | 1.732 | 1.00 | |
| 118_I | 135_F | 1.725 | 1.00 | |
| 9_G | 12_E | 1.723 | 1.00 | |
| 79_E | 105_A | 1.714 | 1.00 | |
| 239_M | 243_T | 1.704 | 1.00 | |
| 93_S | 166_D | 1.697 | 1.00 | |
| 221_S | 224_M | 1.682 | 1.00 | |
| 140_A | 156_T | 1.668 | 1.00 | |
| 158_D | 161_S | 1.666 | 1.00 | |
| 91_N | 113_H | 1.653 | 1.00 | |
| 31_V | 36_I | 1.636 | 1.00 | |
| 86_A | 109_A | 1.636 | 1.00 | |
| 82_A | 109_A | 1.631 | 1.00 | |
| 74_Q | 209_S | 1.618 | 1.00 | |
| 105_A | 108_H | 1.614 | 1.00 | |
| 166_D | 200_R | 1.599 | 1.00 | |
| 99_I | 150_G | 1.581 | 1.00 | |
| 139_L | 151_I | 1.561 | 1.00 | |
| 126_A | 139_L | 1.553 | 1.00 | |
| 161_S | 194_A | 1.55 | 1.00 | |
| 74_Q | 77_E | 1.549 | 1.00 | |
| 181_L | 204_L | 1.547 | 1.00 | |
| 40_L | 56_A | 1.513 | 1.00 | |
| 7_H | 46_Q | 1.512 | 1.00 | |
| 11_I | 14_V | 1.488 | 1.00 | |
| 144_L | 151_I | 1.483 | 1.00 | |
| 11_I | 48_L | 1.476 | 1.00 | |
| 9_G | 13_L | 1.468 | 1.00 | |
| 84_K | 250_E | 1.468 | 1.00 | |
| 118_I | 129_L | 1.464 | 1.00 | |
| 140_A | 159_F | 1.462 | 1.00 | |
| 158_D | 162_Q | 1.441 | 1.00 | |
| 19_Y | 57_A | 1.438 | 1.00 | |
| 169_I | 203_M | 1.409 | 1.00 | |
| 157_L | 190_R | 1.399 | 0.99 | |
| 34_Q | 38_R | 1.381 | 0.99 | |
| 211_F | 228_V | 1.381 | 0.99 | |
| 202_V | 225_V | 1.378 | 0.99 | |
| 204_L | 225_V | 1.377 | 0.99 | |
| 88_Q | 203_M | 1.374 | 0.99 | |
| 140_A | 151_I | 1.369 | 0.99 | |
| 92_G | 115_N | 1.356 | 0.99 | |
| 13_L | 20_V | 1.351 | 0.99 | |
| 194_A | 197_E | 1.346 | 0.99 | |
| 17_Q | 24_E | 1.344 | 0.99 | |
| 161_S | 197_E | 1.342 | 0.99 | |
| 194_A | 198_N | 1.335 | 0.99 | |
| 88_Q | 229_Y | 1.331 | 0.99 | |
| 240_Q | 244_D | 1.321 | 0.99 | |
| 235_P | 238_V | 1.313 | 0.99 | |
| 8_N | 12_E | 1.309 | 0.99 | |
| 86_A | 106_V | 1.308 | 0.99 | |
| 181_L | 225_V | 1.284 | 0.99 | |
| 82_A | 86_A | 1.271 | 0.99 | |
| 79_E | 109_A | 1.261 | 0.99 | |
| 201_H | 226_D | 1.259 | 0.99 | |
| 10_I | 25_L | 1.256 | 0.99 | |
| 211_F | 234_P | 1.254 | 0.99 | |
| 9_G | 29_F | 1.239 | 0.98 | |
| 156_T | 191_T | 1.236 | 0.98 | |
| 117_R | 138_I | 1.231 | 0.98 | |
| 143_E | 187_H | 1.214 | 0.98 | |
| 14_V | 58_L | 1.209 | 0.98 | |
| 67_W | 101_T | 1.193 | 0.98 | |
| 86_A | 89_I | 1.185 | 0.98 | |
| 172_I | 206_V | 1.184 | 0.98 | |
| 14_V | 49_I | 1.182 | 0.98 | |
| 78_K | 101_T | 1.18 | 0.98 | |
| 22_T | 40_L | 1.175 | 0.98 | |
| 175_I | 211_F | 1.173 | 0.98 | |
| 174_G | 182_L | 1.166 | 0.97 | |
| 77_E | 231_D | 1.16 | 0.97 | |
| 172_I | 219_M | 1.156 | 0.97 | |
| 21_S | 24_E | 1.152 | 0.97 | |
| 75_T | 105_A | 1.146 | 0.97 | |
| 100_G | 103_P | 1.144 | 0.97 | |
| 177_S | 180_S | 1.143 | 0.97 | |
| 20_V | 25_L | 1.138 | 0.97 | |
| 107_A | 129_L | 1.131 | 0.97 | |
| 172_I | 204_L | 1.12 | 0.96 | |
| 9_G | 28_H | 1.113 | 0.96 | |
| 117_R | 136_R | 1.107 | 0.96 | |
| 220_G | 224_M | 1.097 | 0.96 | |
| 23_E | 33_P | 1.096 | 0.96 | |
| 13_L | 16_Q | 1.094 | 0.96 | |
| 103_P | 106_V | 1.093 | 0.96 | |
| 175_I | 206_V | 1.091 | 0.96 | |
| 52_H | 55_G | 1.08 | 0.95 | |
| 49_I | 56_A | 1.078 | 0.95 | |
| 85_V | 229_Y | 1.069 | 0.95 | |
| 85_V | 106_V | 1.066 | 0.95 | |
| 91_N | 115_N | 1.051 | 0.94 | |
| 203_M | 229_Y | 1.045 | 0.94 | |
| 77_E | 208_H | 1.042 | 0.94 | |
| 107_A | 128_T | 1.041 | 0.94 | |
| 145_R | 188_E | 1.035 | 0.94 | |
| 102_T | 207_D | 1.022 | 0.93 | |
| 7_H | 42_E | 1.022 | 0.93 | |
| 193_R | 197_E | 1.02 | 0.93 | |
| 203_M | 226_D | 1.01 | 0.93 | |
| 240_Q | 243_T | 1.008 | 0.93 | |
| 197_E | 224_M | 1.007 | 0.93 | |
| 88_Q | 250_E | 1.006 | 0.93 | |
| 138_I | 143_E | 1.003 | 0.93 | |
| 78_K | 210_K | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1stzA | 3 | 0.9405 | 100 | 0.513 | Contact Map | 0.269 |
| 3rrlB | 2 | 0.6706 | 100 | 0.52 | Contact Map | 0.577 |
| 2w48A | 4 | 0.9405 | 100 | 0.58 | Contact Map | 0.605 |
| 4io1A | 2 | 0.6349 | 100 | 0.601 | Contact Map | 0.699 |
| 3l7oA | 2 | 0.6032 | 100 | 0.605 | Contact Map | 0.728 |
| 4gmkA | 2 | 0.6151 | 100 | 0.606 | Contact Map | 0.738 |
| 1o8bA | 2 | 0.6111 | 100 | 0.611 | Contact Map | 0.586 |
| 1m0sA | 2 | 0.6111 | 100 | 0.617 | Contact Map | 0.711 |
| 2o0mA | 1 | 0.9563 | 100 | 0.618 | Contact Map | 0.524 |
| 1lk5A | 4 | 0.6071 | 100 | 0.62 | Contact Map | 0.745 |
Sequence Conservation (Image Generated using WebLogo v3)