| UniProt: | P52598 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13103 | ||
| Length: | 255 (252) | ||
| Sequences: | 3462 | ||
| Seq/Len: | 13.74 |
| YGBI
Paralog alert: 0.83 [within 20: 0.11] - ratio of genomes with paralogs Cluster includes: AGAR DEOR FUCR GATR GLPR SGCR SRLR ULAR YCIT YDJF YGBI YIHW |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 107_I | 205_V | 3.593 | 1.00 | |
| 94_S | 168_Q | 3.266 | 1.00 | |
| 85_L | 88_S | 3.012 | 1.00 | |
| 169_A | 199_S | 2.754 | 1.00 | |
| 99_D | 192_K | 2.754 | 1.00 | |
| 137_T | 144_A | 2.546 | 1.00 | |
| 13_M | 28_R | 2.261 | 1.00 | |
| 168_Q | 203_V | 2.204 | 1.00 | |
| 109_Q | 129_Y | 2.126 | 1.00 | |
| 196_A | 220_L | 2.061 | 1.00 | |
| 203_V | 227_Q | 2.018 | 1.00 | |
| 97_Y | 166_I | 1.967 | 1.00 | |
| 168_Q | 201_Q | 1.961 | 1.00 | |
| 218_L | 221_P | 1.933 | 1.00 | |
| 227_Q | 250_L | 1.921 | 1.00 | |
| 86_A | 205_V | 1.898 | 1.00 | |
| 166_I | 195_I | 1.895 | 1.00 | |
| 86_A | 170_F | 1.869 | 1.00 | |
| 234_L | 239_S | 1.865 | 1.00 | |
| 120_V | 166_I | 1.857 | 1.00 | |
| 13_M | 17_K | 1.84 | 1.00 | |
| 97_Y | 195_I | 1.823 | 1.00 | |
| 90_V | 111_L | 1.804 | 1.00 | |
| 208_A | 231_D | 1.796 | 1.00 | |
| 107_I | 170_F | 1.789 | 1.00 | |
| 25_L | 36_I | 1.78 | 1.00 | |
| 196_A | 202_R | 1.771 | 1.00 | |
| 201_Q | 227_Q | 1.767 | 1.00 | |
| 91_Q | 94_S | 1.766 | 1.00 | |
| 84_K | 110_H | 1.762 | 1.00 | |
| 119_V | 136_C | 1.757 | 1.00 | |
| 239_S | 243_V | 1.747 | 1.00 | |
| 98_L | 104_T | 1.729 | 1.00 | |
| 9_I | 12_E | 1.729 | 1.00 | |
| 80_A | 106_A | 1.725 | 1.00 | |
| 221_P | 224_E | 1.684 | 1.00 | |
| 141_T | 157_A | 1.683 | 1.00 | |
| 94_S | 167_D | 1.682 | 1.00 | |
| 159_T | 162_R | 1.665 | 1.00 | |
| 92_P | 115_E | 1.655 | 1.00 | |
| 31_V | 36_I | 1.645 | 1.00 | |
| 92_P | 114_M | 1.638 | 1.00 | |
| 87_A | 110_H | 1.629 | 1.00 | |
| 75_A | 209_T | 1.629 | 1.00 | |
| 83_G | 110_H | 1.625 | 1.00 | |
| 106_A | 109_Q | 1.587 | 1.00 | |
| 167_D | 200_R | 1.581 | 1.00 | |
| 100_A | 151_S | 1.575 | 1.00 | |
| 162_R | 194_A | 1.574 | 1.00 | |
| 127_A | 140_H | 1.546 | 1.00 | |
| 75_A | 78_Q | 1.544 | 1.00 | |
| 140_H | 152_C | 1.54 | 1.00 | |
| 11_L | 48_A | 1.536 | 1.00 | |
| 7_R | 46_Q | 1.528 | 1.00 | |
| 181_I | 204_L | 1.512 | 1.00 | |
| 40_L | 56_V | 1.505 | 1.00 | |
| 141_T | 160_M | 1.476 | 1.00 | |
| 85_L | 250_L | 1.475 | 1.00 | |
| 11_L | 14_V | 1.469 | 1.00 | |
| 119_V | 130_L | 1.464 | 1.00 | |
| 145_V | 152_C | 1.454 | 1.00 | |
| 170_F | 203_V | 1.452 | 1.00 | |
| 9_I | 13_M | 1.443 | 1.00 | |
| 159_T | 163_S | 1.44 | 1.00 | |
| 19_I | 57_Q | 1.438 | 1.00 | |
| 211_Y | 228_I | 1.403 | 0.99 | |
| 93_G | 116_S | 1.403 | 0.99 | |
| 89_L | 229_I | 1.402 | 0.99 | |
| 17_K | 24_E | 1.38 | 0.99 | |
| 34_M | 38_R | 1.379 | 0.99 | |
| 158_A | 190_T | 1.373 | 0.99 | |
| 141_T | 152_C | 1.372 | 0.99 | |
| 202_R | 225_F | 1.365 | 0.99 | |
| 194_A | 198_A | 1.358 | 0.99 | |
| 87_A | 107_I | 1.352 | 0.99 | |
| 194_A | 197_S | 1.347 | 0.99 | |
| 162_R | 197_S | 1.342 | 0.99 | |
| 89_L | 203_V | 1.34 | 0.99 | |
| 8_Q | 12_E | 1.337 | 0.99 | |
| 240_R | 244_K | 1.336 | 0.99 | |
| 204_L | 225_F | 1.33 | 0.99 | |
| 13_M | 20_V | 1.306 | 0.99 | |
| 235_P | 238_A | 1.304 | 0.99 | |
| 201_Q | 226_D | 1.269 | 0.99 | |
| 10_I | 25_L | 1.267 | 0.99 | |
| 83_G | 87_A | 1.255 | 0.99 | |
| 9_I | 29_M | 1.254 | 0.99 | |
| 14_V | 58_S | 1.252 | 0.99 | |
| 157_A | 191_V | 1.246 | 0.98 | |
| 181_I | 225_F | 1.244 | 0.98 | |
| 80_A | 110_H | 1.229 | 0.98 | |
| 144_A | 187_D | 1.229 | 0.98 | |
| 68_H | 102_T | 1.223 | 0.98 | |
| 118_T | 139_I | 1.217 | 0.98 | |
| 175_S | 182_S | 1.217 | 0.98 | |
| 211_Y | 234_L | 1.216 | 0.98 | |
| 87_A | 90_V | 1.204 | 0.98 | |
| 176_W | 211_Y | 1.194 | 0.98 | |
| 79_K | 102_T | 1.188 | 0.98 | |
| 14_V | 49_V | 1.17 | 0.97 | |
| 22_I | 40_L | 1.165 | 0.97 | |
| 173_A | 219_A | 1.162 | 0.97 | |
| 49_V | 56_V | 1.152 | 0.97 | |
| 173_A | 206_C | 1.152 | 0.97 | |
| 101_G | 104_T | 1.15 | 0.97 | |
| 21_S | 24_E | 1.148 | 0.97 | |
| 20_V | 25_L | 1.141 | 0.97 | |
| 76_M | 106_A | 1.137 | 0.97 | |
| 86_A | 229_I | 1.136 | 0.97 | |
| 176_W | 206_C | 1.136 | 0.97 | |
| 220_L | 224_E | 1.136 | 0.97 | |
| 173_A | 204_L | 1.128 | 0.97 | |
| 9_I | 28_R | 1.127 | 0.97 | |
| 108_A | 130_L | 1.119 | 0.96 | |
| 52_V | 55_G | 1.117 | 0.96 | |
| 78_Q | 231_D | 1.112 | 0.96 | |
| 23_A | 33_H | 1.11 | 0.96 | |
| 13_M | 16_E | 1.098 | 0.96 | |
| 118_T | 137_T | 1.093 | 0.96 | |
| 104_T | 107_I | 1.083 | 0.96 | |
| 92_P | 116_S | 1.061 | 0.95 | |
| 86_A | 107_I | 1.047 | 0.94 | |
| 103_T | 207_D | 1.045 | 0.94 | |
| 89_L | 250_L | 1.044 | 0.94 | |
| 7_R | 42_K | 1.037 | 0.94 | |
| 146_C | 188_K | 1.031 | 0.94 | |
| 203_V | 229_I | 1.028 | 0.94 | |
| 108_A | 129_Y | 1.026 | 0.94 | |
| 240_R | 243_V | 1.025 | 0.93 | |
| 78_Q | 208_A | 1.024 | 0.93 | |
| 161_L | 194_A | 1.013 | 0.93 | |
| 79_K | 210_K | 1.01 | 0.93 | |
| 193_R | 197_S | 1.003 | 0.93 | |
| 141_T | 161_L | 1.003 | 0.93 | |
| 97_Y | 198_A | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1stzA | 3 | 0.9412 | 100 | 0.508 | Contact Map | 0.266 |
| 3rrlB | 2 | 0.6706 | 100 | 0.509 | Contact Map | 0.565 |
| 2w48A | 4 | 0.9255 | 100 | 0.574 | Contact Map | 0.603 |
| 4io1A | 2 | 0.6353 | 100 | 0.606 | Contact Map | 0.703 |
| 3l7oA | 2 | 0.6039 | 100 | 0.606 | Contact Map | 0.737 |
| 2o0mA | 1 | 0.949 | 100 | 0.607 | Contact Map | 0.522 |
| 4gmkA | 2 | 0.6157 | 100 | 0.608 | Contact Map | 0.744 |
| 1o8bA | 2 | 0.6118 | 100 | 0.615 | Contact Map | 0.595 |
| 1lk5A | 4 | 0.6078 | 100 | 0.621 | Contact Map | 0.746 |
| 1m0sA | 2 | 0.6118 | 100 | 0.621 | Contact Map | 0.725 |
Sequence Conservation (Image Generated using WebLogo v3)